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DNA and RNA Isolation Techniques: Market Developments, Growth Areas and Opportunities 2014 - Product Image

DNA and RNA Isolation Techniques: Market Developments, Growth Areas and Opportunities 2014

  • ID: 2770787
  • January 2014
  • Region: Global
  • 153 Pages
  • BioPharm Reports (VennBio Ltd.)

Extraction methods used to isolate DNA and RNA are fundamental to most studies carried out in the molecular biology field. These molecules are isolated prior to downstream processing for a wide range of applications, from fundamental research to routine diagnostic and therapeutic decision-making. In the past, methods used to extract nucleic acids were often complex, time-consuming, labour-intensive and limited in throughput. Today, many specialized methods are available to scientists, from conventional solution-based approaches, to solid-phase systems that are often used in commercial kits.

Developments in this field are allowing scientists to evaluate new techniques in their own areas of application. Some of these are also amenable to automation, an increasing requirement in many of today’s laboratories. Biopharm Reports has carried out a global market study of DNA and RNA isolation techniques involving the participation of 227 experienced end-users in this field. Participants mean 'years of experience' in the use of DNA and RNA isolation techniques was 14.4 years and the findings of this study provide a wealth of information relevant to suppliers in this field. In particular, READ MORE >

Index

Executive Summary

Chapter 1. Background
1.1 Introduction
1.2 Background
1.3 Study Questions

Chapter 2. Study Participants
Summary
2.1 This Chapter
2.2 Market Questions
2.3 Countries
2.4 Regions
2.5 Participant Positions
2.6 Participant Experience
2.7 Participant Organisations
2.8 Participant Fields
2.9 Discussion and Opportunities

Chapter 3. DNA and RNA Forms
Summary
3.1 This Chapter
3.2 Market Questions
3.3 Current DNA and RNA Forms
3.4 Other Forms
3.5 Future DNA and RNA Forms
3.6 Other Forms
3.7 Comparative Analysis
3.8 Discussion and Opportunities

Chapter 4. Solutions-Phase vs. Solid-Phase Methods
Summary
4.1 This Chapter
4.2 Market Questions
4.3 Current Solution-Phase vs. Solid-Phase
4.4 Other Techniques
4.5 Future Solution-Phase vs. Solid-Phase
4.6 Other Techniques
4.7 Discussion and Opportunities

Chapter 5. Kit vs. Non-Kit Methods
Summary
5.1 This Chapter
5.2 Market Questions
5.3 Current Kit vs. Non-Kit Methods
5.4 Future Kit vs. Non-Kit Methods
5.5 Current use of Kits in all Nucleic Acid (NA) Forms
5.6 Future use of Kits in all Nucleic Acid Forms
5.7 Current use of Non-Kit Methods for all Nucleic Acid Forms
5.8 Future use of Non-Kit Methods for all Nucleic Acid Forms
5.9 Current Other Methods Overall
5.10 Future Other Methods Overall
5.11 Current Methods for Genomic DNA
5.12 Future Methods for Genomic DNA
5.13 Current Methods for MicroRNA
5.14 Future Methods for MicroRNA
5.15 Current Methods for mRNA
5.16 Future Methods for mRNA
5.17 Current Methods for Ribosomal RNA (rRNA)
5.18 Future Methods for Ribosomal RNA (rRNA)
5.19 Current Methods for SiRNA
5.20 Future Methods for SiRNA
5.21 Current Methods for snRNA
5.22 Future Methods for snRNA
5.23 Current Methods for tRNA
5.24 Future Methods for tRNA
5.25 Main Method
5.26 Discussion and Opportunities

Chapter 6. Solution-Phase DNA/RNA Isolation (Non-Kits)
Summary
6.1 This Chapter
6.2 Market Questions
6.3 Current Preferred Methods
6.4 Current Preferred Suppliers
6.5 Future Preferred Methods
6.6 Future Preferred Suppliers
6.7 Advantages and Disadvantages
6.8 Discussion and Opportunities

Chapter 7. Solid-Phase DNA/RNA Isolation (Non-Kits)
7.1 This Chapter
7.2 Market Questions
7.3 Current Preferred Methods
7.4 Current Preferred Suppliers
7.5 Future Preferred Methods
7.6 Future Preferred Suppliers
7.7 Advantages and Disadvantages
7.8 Discussion and Opportunities

Chapter 8. Isolation Kits
8.1 This Chapter
8.2 Market Questions
8.3 DNA Kits - Current Preferred Suppliers
8.4 DNA - Current Preferred Kits
8.5 DNA Kits – Future Preferred Suppliers
8.6 DNA - Future Preferred Kits
8.7 RNA Kits - Current Preferred Suppliers
8.8 Current Preferred RNA Kits
8.9 RNA Kits – Future Preferred Suppliers
8.10 RNA - Future Preferred Kits
8.11 Advantages and Disadvantages
8.12 Discussion and Opportunities

Chapter 9. Automation
9.1 This Chapter
9.2 Market Questions
9.3 Use of Automated Methods
9.4 Current Automated Methods
9.5 Future Automated Methods
9.6 DNA Isolation - Preferred Companies
9.7 DNA Isolation - Methods
9.8 RNA isolation - Preferred Companies
9.9 RNA isolation - Methods
9.10 Discussion and Opportunities

Chapter 10. Applications
10.1 This Chapter
10.2 Market Questions
10.3 Current Applications
10.4 Future Applications
10.5 Discussion and Opportunities

Chapter 11. Therapeutic Areas
11.1 This Chapter
11.2 Market Questions
11.3 Therapeutic Areas
11.4 Discussion and Opportunities

Chapter 12. Purpose
12.1 This Chapter
12.2 Market Questions
12.3 Specialist Areas
12.4 Purpose
12.5 Discussion and Opportunities

Chapter 13. Samples
13.1 This Chapter
13.2 Market Questions
13.3 Study Samples
13.4 Discussion and Opportunities

Chapter 14. Disease Biomarkers
14.1 This Chapter
14.2 Market Questions
14.3 Study of Disease Biomarkers
14.4 Current Disease Biomarkers
14.5 Future Disease Biomarkers
14.6 Biomarker utility
14.7 Discussion and Opportunities

Chapter 15. Budgets and Expenditure
15.1 This Chapter
15.2 Market Questions
15.3 Cost per Sample (Non-Kit)
15.4 Cost per Sample (Kit)
15.5 Current Budget Breakdown
15.6 Future Budgets
15.7 Discussion and Opportunities

Chapter 16. Consumables
16.1 This Chapter
16.2 Market Questions
16.3 Consumables
16.4 Discussion and Opportunities

Chapter 17. Discussion and Opportunities
17.1 Discussion and Opportunities

Appendices

Figures

Figure 2.1 Top ten countries and the percentages of individuals who participated in DNA RNA 2014
Figure 2.2 Regions and associated percentages of individuals who participated in DNA RNA 2014
Figure 2.3 Professional positions (and %) of individuals who participated in DNA RNA 2014
Figure 2.4 Participants' 'years of experience' in the use of techniques to extract DNA and RNA (Study DNA RNA 2014)
Figure 2.5 Organisation types indicated by participants in DNA RNA 2014
Figure 2.6 Field types indicated by participants in DNA RNA 2014
Figure 3.1 Current nucleic acid forms studied by participants in DNA RNA 2014
Figure 3.2 Nucleic acid forms anticipated to be studied in three years from now, by participants in DNA RNA 2014
Figure 4.1 Current techniques used for the isolation of DNA or RNA, indicated by participants in DNA RNA 2014
Figure 4.2 Future techniques used for the isolation of DNA or RNA, indicated by participants in DNA RNA 2014
Figure 5.1 Overall current use of kit and non-kit methods for the isolation of DNA and RNA, reported by participants in DNA RNA 2014
Figure 5.2 Overall anticipated use of kit and non-kit methods for the isolation of DNA and RNA in three years from now, reported by participants in DNA RNA 2014
Figure 5.3 Current use of kits for the isolation of all nucleic acid forms, reported by participants in DNA RNA 2014
Figure 5.4 Anticipated use of kits for the isolation of all nucleic acid forms in three years from now, reported by participants in DNA RNA 2014
Figure 5.5 Current use of non-kit methods or the isolation of all nucleic acid forms, reported by participants in DNA RNA 2014
Figure 5.6 Anticipated use of non-kit methods or the isolation of all nucleic acid forms in three years from now, reported by participants in DNA RNA 2014
Figure 5.7 Current use of other isolation methods for all NA forms, reported by participants in DNA RNA 2014
Figure 5.8 Use of other isolation methods for all NA forms in three years from now, reported by participants in DNA RNA 2014
Figure 5.9 Current isolation methods for genomic DNA, reported by participants in DNA RNA 2014
Figure 5.10 Anticipated use of isolation methods for genomic DNA in three years from now, reported by participants in DNA RNA 2014
Figure 5.11 Current isolation methods for microRNA, reported by participants in DNA RNA 2014
Figure 5.12 Isolation methods anticipated to be used for microRNA in three years from now , reported by participants in DNA RNA 2014
Figure 5.13 Current isolation methods for microRNA, reported by participants in DNA RNA 2014
Figure 5.14 Isolation methods anticipated to be used for microRNA in three years from now, reported by participants in DNA RNA 2014
Figure 5.15 Current isolation methods for ribosomal RNA, reported by participants in DNA RNA 2014
Figure 5.16 Isolation methods anticipated to be used for ribosomal RNA in three years from now, reported by participants in DNA RNA 2014
Figure 5.17 Current isolation methods for SiRNA, reported by participants in DNA RNA 2014
Figure 5.18 Isolation methods anticipated to be used for SiRNA in three years from now, reported by participants in DNA RNA 2014
Figure 5.19 Current isolation methods for snRNA, reported by participants in DNA RNA 2014
Figure 5.20 Isolation methods anticipated to be used for snRNA in three years from now, reported by participants in DNA RNA 2014
Figure 5.21 Current isolation methods for tRNA, reported by participants in DNA RNA 2014
Figure 5.22 Isolation methods anticipated to be used for tRNA in three years from now, reported by participants in DNA RNA 2014
Figure 5.23 Main methods used for the isolation of DNA and RNA, reported by participants in DNA RNA 2014
Figure 5.24 Changes in the use of Kit and Non-Kit methods over the next three years (2014 – 2016), reported by participants in DNA RNA 2014
Figure 6.1 The top five current solution phase (non-kit) methods for the extraction of DNA/RNA, reported by participants in DNA RNA 2014
Figure 6.2 Top current preferred suppliers of solution phase (non-kit) products for the extraction of DNA/RNA, reported by participants in DNA RNA 2014
Figure 6.3 The top five preferred solution-phase (non-kit) methods for the isolation
of DNA/RNA in three years from now, reported by participants in DNA RNA 2014
Figure 6.4 Top preferred suppliers of solution phase (non-kit) methods for the isolation of
DNA/RNA in three years from now, reported by participants in DNA RNA 2014
Figure 6.5 Advantages of solution phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Figure 6.6 Disadvantages of solution phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Figure 7.1 Top current preferred solid-phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Figure 7.2 Top current preferred suppliers of solid-phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Figure 7.3 Top anticipated preferred solid-phase (non-kit) methods for the isolation of DNA/RNA in three years from now, reported by participants in DNA RNA 2014
Figure 7.4 Top anticipated preferred suppliers of solid-phase (non-kit) methods for the isolation
of DNA/RNA in three years from now, reported by participants in DNA RNA 2014
Figure 7.5 Advantages of solid-phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Figure 7.6 Disadvantages of solid-phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Figure 8.1 Preferred current suppliers of kits for isolating DNA, reported by participants in DNA RNA 2014
Figure 8.2 Preferred anticipated future suppliers of kits for isolating DNA, reported by participants in DNA RNA 2014
Figure 8.3 Current preferred suppliers of kits for isolating RNA, reported by participants in DNA RNA 2014
Figure 8.4 Future preferred suppliers of kits for isolating RNA, reported by participants in DNA RNA 2014
Figure 8.5 The advantages of using DNA and RNA isolation kits, reported by participants in DNA RNA 2014
Figure 8.6 The disadvantages of using DNA and RNA isolation kits, reported by participants in DNA RNA 2014
Figure 9.1 The use of automated methods for the isolation of DNA and RNA, reported by participants in DNA RNA 2014
Figure 9.2 The current percentage of DNA and RNA isolation methods that are automated, indicated by participants in DNA RNA 2014 who use automated methods
Figure 9.3 The percentage of DNA/RNA isolation methods anticipated to be automated in three
years from now, indicated by participants in DNA RNA 2014 who use automated methods
Figure 9.4 Top five preferred companies for the automation of DNA isolation, indicated by participants in DNA RNA 2014 who currently use automated methods
Figure 9.5 Top three preferred companies for the automation of RNA isolation, indicated by participants in DNA RNA 2014 who currently use automated methods
Figure 10.1 Top current applications associated with DNA and RNA isolation methods, used by participants in DNA RNA 2014
Figure 10.2 Top applications associated with DNA and RNA isolation methods that are
anticipated to be used in three years from now, by participants in DNA RNA 2014
Figure 11.1 Top therapeutic areas associated with DNA and RNA isolation methods used by participants in DNA RNA 2014
Figure 12.1 Top specialist areas associated with the use of DNA and RNA isolation methods, reported by participants in DNA RNA 2014
Figure 12.2 Top purposes or reasons associated with the use of DNA and RNA isolation methods, reported by participants in DNA RNA 2014
Figure 13.1 Top study samples processed using DNA and RNA isolation methods used by participants in DNA RNA 2014
Figure 14.1 The study of disease biomarkers associated with the use of DNA and RNA isolation methods, indicated by participants in DNA RNA 2014
Figure 14.1 Top current disease biomarkers associated with the use of DNA and RNA isolation methods, indicated by participants in DNA RNA 2014
Figure 14.2 Top disease biomarkers associated with the use of DNA and RNA isolation methods anticipated to be studied three years from now, indicated by participants in DNA RNA 2014
Figure 14.3 Top disease biomarkers clinical utilities relating to their use of DNA and RNA isolation methods, indicated by participants in DNA RNA 2014
Figure 15.1 Per-sample non-kits costs and associated percentages of end-users, indicated by participants in DNA RNA 2014
Figure 15.2 Per-sample kits costs and associated percentages of end-users, indicated by participants in DNA RNA 2014
Figure 15.3 Budget costing areas relating to the isolation of DNA and RNA, indicated by participants in DNA RNA 2014
Figure 16.1 Top three consumables (by cost) in the isolation of DNA or RNA, indicated by participants in DNA RNA 2014
Appendix 1. Top three consumables (by cost) used in the isolation of DNA or RNA, indicated by participants in DNA RNA 2014

Tables

Table 2.1 Countries, percentages and numbers (No) of individuals who participated in DNA RNA 2014
Table 2.1 Countries, percentages and numbers (No) of individuals who participated in DNA RNA 2014
Table 2.2 Regions, associated percentages and numbers (No) of individuals who participated in DNA RNA 2014
Table 2.3 Professional positions (% and number, No) of individuals who participated in DNA RNA 2014
Table 2.4 Participants' 'years of experience' in the use of techniques to extract DNA and RNA (Study DNA RNA 2014)
Table 2.4 Participants' 'years of experience' in the use of techniques to extract DNA and RNA (Study DNA RNA 2014)
Table 2.5 Organisation types indicated by participants in DNA RNA 2014
Table 2.6 Field types indicated by participants in DNA RNA 2014
Table 2.7 Other field types indicated by participants in DNA RNA 2014
Table 3.1 Current nucleic acid forms (as % total) and those anticipated to be studied
three years from now (as a % of total), indicated by participants in DNA RNA 2014
Table 6.1 Current solution-phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Table 6.2 Current preferred suppliers of solution phase (non-kit) products for the extraction of DNA/RNA, reported by participants in DNA RNA 2014
Table 6.3 Preferred solution-phase (non-kit) methods for the isolation of DNA/RNA in three years from now, reported by participants in DNA RNA 2014
Table 6.4 Preferred suppliers of solution phase (non-kit) methods for the isolation of
DNA/RNA in three years from now, reported by participants in DNA RNA 2014
Table 6.5 Advantages of solution phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Table 6.6 Disadvantages of solution phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Table 7.1 Current preferred solid-phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Table 7.2 Current preferred suppliers of solid-phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Table 7.3 Anticipated preferred solid-phase (non-kit) methods for the isolation of DNA/RNA in three years from now, reported by participants in DNA RNA 2014
Table 7.4 Anticipated preferred suppliers of solid-phase (non-kit) methods for the isolation
of DNA/RNA in three years from now, reported by participants in DNA RNA 2014
Table 7.5 Advantages of solid-phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Table 7.6 Disadvantages of solid-phase (non-kit) methods for the isolation of DNA/RNA, reported by participants in DNA RNA 2014
Table 8.1 Preferred current suppliers of kits for isolating DNA, reported by participants in DNA RNA 2014
Table 8.2 Preferred kits currently for isolating DNA, reported by participants in DNA RNA 2014
Table 8.3 Preferred anticipated future suppliers of kits for isolating DNA, reported by participants in DNA RNA 2014
DNA RNA 2014
Table 8.4 Future preferred kits for isolating DNA reported by participants in DNA RNA 2014
Continued Table 8.4 Future preferred kits for isolating DNA, reported by participants in DNA RNA 2014 Continued Table 8.4 Future preferred kits for isolating
DNA, reported by participants in DNA RNA 2014
Table 8.5 Current preferred suppliers of kits for isolating RNA, reported by participants in DNA RNA 2014
Table 8.6 Current preferred kits for isolating RNA, reported by participants in DNA RNA 2014
Table 8.7 Future preferred suppliers of kits for isolating RNA, reported by participants in DNA RNA 2014
Table 8.8 Future preferred suppliers of kits for isolating RNA, reported by participants in DNA RNA 2014
Table 9.1 Preferred companies for the automation of DNA isolation, indicated by participants in DNA RNA 2014 who currently use automated methods
Table 9.2 Automation platforms and companies for DNA isolation, indicated by participants in DNA RNA 2014
Table 9.3 Preferred companies for the automation of RNA isolation, indicated by participants in DNA RNA 2014 who currently use automated methods
Table 9.4 Automation methods and companies for RNA isolation, indicated by participants in DNA RNA 2014
Table 10.1 Current applications associated with DNA and RNA isolation methods, used by participants in DNA RNA 2014
Table 10.2 Applications associated with DNA and RNA isolation methods that are anticipated to be used in three years from now, by participants in DNA RNA 2014
Table 11.1 Therapeutic areas associated with DNA and RNA isolation methods used by participants in DNA RNA 2014
Table 12.1 Specialist areas associated with the use of DNA and RNA isolation methods, reported by participants in DNA RNA 2014
Table 12.2 Purposes or reasons associated with the use of DNA and RNA isolation methods, reported by participants in DNA RNA 2014
Table 13.1 Study samples processed using DNA and RNA isolation methods used by participants in DNA RNA 2014
Table 14.1 Current disease biomarkers associated with the use of DNA and RNA isolation methods, indicated by participants in DNA RNA 2014
Table 14.2 Disease biomarkers associated with the use of DNA and RNA isolation methods anticipated to be studied three years from now, indicated by participants in DNA RNA 2014
Table 14.3 Disease biomarkers clinical utilities relating to their use of DNA and RNA isolation methods, indicated by participants in DNA RNA 2014
Table 15.1 Per-sample non-kits costs and associated percentages of end-users, indicated by participants in DNA RNA 2014
Table 15.2 Per-sample kits costs and associated percentages of end-users, indicated by participants in DNA RNA 2014
Table 15.3 Budget costing areas relating to the isolation of DNA and RNA, indicated by participants in DNA RNA 2014
Table 15.4 Future overall budget relating to the isolation of DNA and RNA, indicated by participants in DNA RNA 2014
Table 16.1 Top three consumables (by cost) used in the isolation of DNA or RNA, indicated by participants in DNA RNA 2014
Appendix 1. Top three consumables (by cost) used in the isolation of DNA or RNA, indicated by participants in DNA RNA 2014

Market findings from this study are based on 'real world' laboratory data, provided by research scientists and clinicians who routinely use nucleic acid isolation methods.

This study investigated 45 market areas on current activities, recent developments and trends, anticipated future growth, shrinkage and opportunities. Its findings provide market information on the current and developing use of nucleic acid isolation methods and assist companies selling into these markets to respond to laboratory users’ current needs and their future plans.

Biopharm Reports specialises in carrying out market studies of techniques and applications used in life science laboratories and clinics. All our studies involve the participation of scientists and clinicians and investigate in-depth, key areas of their current use of specialised laboratory techniques, and their plans for using these techniques over the next three years.

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