The 'epi-(Greek for 'over', 'above')genome', with its rich cache of highly regulated, structural modifications-including DNA methylation, histone modifications and histone variants-defines the moldings and three-dimensional structures of the genomic material inside the cell nucleus and serves, literally, as a molecular bridge linking the environment to the genetic materials in our brain cells. Due to technological and scientific advances in the field, the field of neuroepigenetics is currently one of the hottest topics in the basic and clinical neurosciences. The volume captures some of this vibrant and exciting new research, and conveys to the reader an up-to-date discussion on the role of epigenetics across the lifespan of the human brain in health and disease.
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Table of Contents
- The Epigenetic Basis of Memory Formation and Storage
Timothy J. Jarome, Jasmyne S. Thomas and Farah D. Lubin - Epigenetics in Post-Traumatic Stress Disorder.
Carina Rampp, Elisabeth B. Binder and Nadine Provençal - Histone-Mediated Epigenetics in Addiction
Leah N. Hitchcock and K. Matthew Lattal - Modeling the Molecular Epigenetic Profile of Psychosis in Prenatally Stressed Mice
Alessandro Guidotti, Erbo Dong, Patricia Tueting and Dennis R. Grayson - Epigenetics of Depression
Sermsak Lolak, Pim Suwannarat and Robert H. Lipsky - Epigenetic Factors and Intellectual Disability: The Rubinstein-Taybi Syndrome as a Paradigm of Neurodevelopmental Disorder with Epigenetic Origin
Jose P. Lopez-Atalaya, Luis M. Valor and Angel Barco - The Intergenerational Effects of Early Adversity
Janina Galler and Danielle Galler Rabinowitz - The Future of Neuroepigenetics in the Human Brain
Amanda Mitchell, Panos Roussos, Cyril Peter, Nadejda Tsankova and Schahram Akbarian
