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The European Markets For PCR Technologies - Product Image

The European Markets For PCR Technologies

  • Published: September 2014
  • Region: Europe
  • 205 Pages
  • AcuBiz Consulting Sdn Bhd
The European market, which accounted for approximately 29% of the global demand for PCR technologies, is expected to grow at a CAGR of 7.2% during 2013-2018.

FEATURED COMPANIES

  • Abacus Diagnostica Oy
  • Ares Bioscience GmbH
  • biomers.net GmbH
  • Eurogentec S.A.
  • highQu GmbH
  • Promega Corporation
  • MORE

Since its invention three decades ago, PCR has evolved to become one of the fundamental technology platforms in life sciences sector. The application segments of this platform are still expanding, driven by the expiry of key PCR patents. The demand for fast, accurate, and affordable diagnosis tests in the healthcare segment has been another key driver of the PCR market. The rising investments in the field of companion diagnostics have also been boosting the demand for PCR. Food safety testing is another significant end-use segment of the technology, driven by both consumer demand and regulatory requirements.

In this report “The European Markets for PCR Technologies”, analysts identify the market dynamics in Europe and forecast the potential of the market. The European market, which accounted for approximately 29% of the global demand for PCR technologies, is expected to grow at a CAGR of 7.2% during 2013-2018. The report estimates the market size of the key product and application segments of PCR and forecasts the growth based on market dynamics of these segments, which can impact the demand for PCR. Various technology segments are also analysed in detail.

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INTRODUCTION
Study Goal and Outline
Rationale for this Study
Targeted Audience
Market Definition and Scope
Information Sources and Methodologies
Customization of this study
Disclaimer

EXECUTIVE SUMMARY

CHAPTER 1: OVERVIEW
Definition of Polymerase Chain Reaction
History of PCR
Table 1: Timeline of PCR Technology History (1983 – 2013)
Table 2: Timeline of Real-Time PCR History
Table 3: Timeline of Digital PCR History
The Concept
Important Considerations
Table 4: Some Important Factors to be Considered while Planning PCR Experiments
PCR Platforms – Popular and Emerging
Allele-specific PCR (ASPCR)
Amplified Fragment Length Polymorphisms PCR (AFLP-PCR)
Assembly PCR
Asymmetric PCR
Capillary PCR
Colony PCR
Table 5: Key Players and Their Products in the Field of Colony PCR
Digital PCR (dPCR)
Table 6: Key Players and Their Products in the Field of Digital PCR
Direct PCR
Table 7: Key Players and Their Products in the Field of Direct PCR
Hot-Start PCR
Table 8: Key Players and Their Products in the Field of Hot-Start PCR
In Situ PCR
Table 9: Key Players and Their Products in the Field of In Situ PCR
Inter-Simple Sequence Repeat PCR (ISSR-PCR)
Inverse PCR
Long PCR
Table 10: Key Players and Their Products in the Field of Long PCR
Long Accurate PCR (LA PCR)
Table 11: Key Players and Their Products in the Field of Long Accurate PCR
Methylation-Specific PCR
Table 12: Key Players and Their Products in the Field of Methylation-Specific PCR
Mini Primer PCR
Multiplex PCR
Table 13: Key Players and Their Products in the Field of Multiplex PCR
Nanoparticle Assisted PCR (Nano PCR)
Nested PCR
Table 14: Key Players and Their Products in the Field of Nested PCR
Overlap-Extension PCR (OE-PCR)
Quantitative Fluorescence PCR (QF-PCR)
Table 15: Key Players and Their Products in the Field of Quantitative Fluorescence PCR
Random Amplified Polymorphic DNA (RAPD) PCR
Table 16: Key Players and Their Products in the Field of Random Amplified Polymorphic DNA PCR
Real-Time PCR
Table 17: Commonly Used Detection Chemistries in Real-Time PCR
Table 18: Key Players and Their Products in the Field of Real-Time PCR
Repetitive Sequence-Based PCR (rep-PCR)
Reverse Transcription PCR (RT-PCR)
Table 19: Key Players and Their Products in the Field of Reverse Transcription PCR
Single Cell PCR
Table 20: Key Players and Their Products in the Field of Single Cell PCR
Solid Phase PCR
Thermal Asymmetric Interlaced PCR (TAIL-PCR)
Touchdown PCR
Universal Fast Walking PCR (UFW)
Table 21: Key Players and Their Products in the Field of Universal Fast Walking PCR
End-Use Segments of PCR
Medical Diagnostics Segments
Cancer
Table 22: Key Players Offering PCR-Based Cancer Diagnostics Products in the Market
Infectious Diseases
Table 23: Key Players Offering PCR-Based Diagnostics Products Targeting Human Infections
Prenatal Diagnostics
Table 24: Key Players Offering PCR-Based Pre-natal Diagnostics Products in the Market
Food Safety Testing, Agricultural, and Environmental Segments
Food-Borne and Water-Borne Infections
Table 25: Common Commercial Systems Used for Food Pathogen Detection
I. Campylobacter and its subspecies (Campylobacter spp.)
Table 26: International Standards and Guidelines for Campylobacter spp. Identification
Table 27: Key Players Offering PCR-Based Kits to Detect Campylobacter and Its Subspecies
II. Escherichia coli (E.coli)
Table 28: International Standards and Guidelines for Escherichia coli Detection
Table 29: Key Players Offering PCR-Based kits to Detect Pathogenic Escherichia coli and Its Subspecies
III. Listeria monocytogenes and its subspecies (Listeria spp.)
Table 30: International Standards and Guidelines for Listeria Detection
Table 31: Key Players Offering PCR-Based kits to Detect Listeria monocytogenes and Its Subspecies
IV. Salmonella and its Subspecies (Salmonella spp.)
Table 32: International Standards and Guidelines for Salmonella Detection
Table 33: Key Players Offering PCR-Based kits to Detect Salmonella and Its Subspecies
V. Other Food-Borne and Water-Borne Pathogens
Table 34: Key Players Offering PCR-Based kits to Detect Other Selected Food-Borne and Water-Borne Pathogens
Veterinary Infection Diagnostics
Table 35: Key Players Offering PCR-Based Veterinary Diagnostics Products
Plant Infection Diagnostics
Table 36: Key Players Offering PCR-Based Diagnostics Products Targeting Plant Infections
GMO Foods/Plants Testing
Table 37: Key Players Offering PCR-Based Kits to Detect GMO Foods/Plants in the Market
Food Allergens and Animal Species in Food
Table 38: Key Players Offering PCR-Based Kits to Detect Food Allergens and Animal Species in Food in the Market
Forensic Sciences
Table 39: Key Players Offering PCR-Based Human Identity and Forensic Testing Products in the Market
Life Sciences Research
miRNA Analysis
Table 40: Key Players Offering Products for MicroRNA Analysis Involving PCR Technology
Mutations Detection
Table 41: Key Players Offering PCR-Based Mutations Detection Products
SNP Detection and Genotyping
Table 42: Key Players Offering PCR-Based Products for SNPs Detection and Genotyping
Sequencing
Table 43: Key Players Offering PCR-Based Sequencing Products
Application of PCR in NGS Library Quantification
Table 44: Key Players Offering NGS Library Quantification Products that Incorporate PCR Technology
Genetic Fingerprinting
Table 45: Key Players Offering PCR-Related Products for Genotyping/DNA Fingerprinting
Site-Directed Mutagenesis (SDM)
Table 46: Key Players Offering PCR-Based Site-Directed Mutagenesis Products
Market Trends
Widening Application Scope
Patent Expiries Promoting Investments in the Sector in the European Union
Table 47: Basic PCR Patents Expired in 28 March 2005 in USA
Table 48: Key Patents in Selected PCR Market Segments and their Expiry Dates in USA
Dominance of PCR over Alternative Pathogen Diagnostics Options
Technological Advancements Enabling High Throughput as well as Point-of-Care (POC) Diagnostics
Advent of Digital PCR
Strong Growth Trends in Single-Cell Analysis (SCA)
Rising Demand for Molecular Diagnostics
Rising Food Safety Testing Regulations
Market Drivers
Table 49: Market Drivers of the European Union PCR Market
Market Challenges
Table 50: Market Restraints of the European Union PCR Markets
Rising Merger and Acquisition Trends
Table 51: Key Mergers and Acquisitions during the Past Five Years Relevant in PCR Market (2010-2014)

CHAPTER 2: INDUSTRY STRUCTURE
The Global PCR Technology Markets
Table 52: Global PCR Technology Markets, By Value (USD, Million)
Figure 1: Market Shares and Forecasts of PCR Technology Market Segments
The Demand for PCR Technologies in Europe
Table 53: PCR Market Segments and their Growth Trends in Europe, By Value (USD, Million)
Analysis of Key End-Use Segments
Table 54: Global PCR Technologies Demand by End-Use Segments, by Value (USD, Million)
Table 55: PCR Technologies Demand by End-Use Segments in Europe, by Value (USD, Million)
Medical Diagnostics
Food, Agriculture, etc.
Life Sciences Research
Figure 2: Market Shares and Forecasts of PCR Technologies Demand in Europe by End-Use Segments

CHAPTER 3: LEGISLATION AND REGULATION
MIQE Guidelines and RDML
Regulatory Landscape of PCR Technologies in Medical Diagnostics Fields
Table 56: Regulatory Agencies Responsible for Molecular Diagnostics in Europe
Table 57: Key Laws and Regulations Influencing PCR-based Medical Diagnostics Markets in Europe
Regulatory Landscape of PCR Technologies Targeting Food and Agricultural Segments
Table 58: Main International Agencies Involved in Food Safety Aspects
Table 59: Selected Regulatory Agencies Responsible for Food Safety and GMO Testing in the EU
Table 60: Food Safety Laws and Regulations Influencing PCR Technologies Markets in the EU

CHAPTER 4: TECHNOLOGY TREND ANALYSIS
Automation of PCR
Touch-screen Options for Ease-of-Use
Networking and Remote Controlling Capabilities
Low Throughput Systems
Lab-On-A-Chip Formats and Portability
Application of Microelectromechanical Systems (MEMS) and Convection Principles in PCR
Automated High Throughput Instruments for Large Scale Applications
Table 61: Selected Companies Enabling High Throughput in qPCR
Table 62: Comparison of the Reaction Formats of Selected Real-Time PCR Instruments in the Market
Evolution in Heating Technologies for Efficient Thermal Cycling
Table 63: Comparison of the Thermal Modules of Selected Commercial Real-Time PCR Systems
Speed
Detectors
Light Source
Table 64: Comparison of the Optical Modules of Selected Real-Time PCR Systems in the Market
Improving Multiplexing Efficiency
Table 65: Technical Approaches Adopted for Limiting Off-Target Amplification in Multiplex qPCR Assays
Fluorescence Chemistry
TaqMan Probe
Molecular Beacons and Scorpions
Table 66: Fluorescence Chemistry and Multiplex Capability of Selected qPCR Systems in the Market
The Early Adopters of dPCR
Widening Scope within Molecular Biology Platforms

CHAPTER 5: COMPANY PROFILES
Abacus Diagnostica Oy
Abbott Laboratories
Figure 3: Abbott Revenue Shares, by Business Segments, 2013
ADNucleis
Affymetrix, Inc.
Table 67: Affymetrix Revenue Shares, by Business Unit, 2013
Figure 4: Affymetrix Revenue Shares, by Product Category, 2013
Agilent Technologies, Inc.
Figure 5: Agilent Technologies Revenue Shares, by Business Group, 2013
AlphaHelix Molecular Diagnostics AB
Altona Diagnostics GmbH
Ampliqon A/S
Analytik Jena AG
AnDiaTec GmbH & Co. KG
Ares Bioscience GmbH
Bibby Scientific Limited
bioMérieux S.A.
Bio-Rad Laboratories, Inc.
Figure 6: Bio-Rad Laboratories Revenue Shares, by Region, 2013
Table 68: Bio-Rad Laboratories Revenue Shares, by Segment, 2013
BioCat GmbH
Biogazelle N.V.
BioGene Ltd.
Bioline Reagents Limited
Biolytix AG
biomers.net GmbH
BIORON GmbH / BIORON Diagnostics GmbH
Biotools Biotechnological and Medical Laboratories S.A.
BJS Biotechnologies Ltd.
Cepheid, Inc.
Table 69: Clinical and Non-Clinical Revenue Shares, 2013
Figure 7: Cepheid Revenue Shares, by Region, 2013
CLONIT srl
CONGEN Biotechnologie GmbH
Devyser AB
Ecoli s.r.o
ELITech Group
Enigma Diagnostics Limited
Eppendorf AG
Figure 8: Eppendorf Revenue Shares, by Region, 2013
Eurogentec S.A.
Exiqon A/S
F. Hoffmann-La Roche Ltd.
Table 70: Roche Diagnostics – Main Businesses and their Revenues, 2013
Figure 9: Roche Diagnostics Revenue Shares, by Region, 2013
Table 71: Selected PCR-Based Companion Diagnostics under Development by Roche
Fluorogenics Ltd.
G-Storm
GeneON GmbH
Genekam Biotechnology AG
GENOMICA S.A.U.
highQu GmbH
inno-train Diagnostik GmbH
Labtech International Ltd.
LGC Genomics Ltd.
LIPSDIAG GmbH
Merck Millipore International
Figure 10: Merck Millipore Revenue Shares, by Region, 2013
Table 72: Merck Millipore Revenue Shares, by Business Segments, 2013
MoBiTec GmbH
Multiplicom N.V.
NimaGen B.V.
PathoFinder B.V.
PEQLAB Biotechnologie GmbH
PrimerDesign Ltd.
Promega Corporation
QIAGEN N.V.
Figure 11: Revenue Distribution by Customer Categories, QIAGEN, 2013
Table 73: Geographic Distribution of QIAGEN Revenues, 2012-2013 (USD, Million)
Sacace Biotechnologies Srl
Sigma-Aldrich Corporation
Table 74: Main Business Units of Sigma-Aldrich and Their Revenue Shares, 2013
Figure 12: Revenue Shares of Sigma-Aldrich Business Units, by Region, 2013
Solis BioDyne
STARLAB Switzerland
TAG Copenhagen A/S
Takara Bio, Inc.
Figure 13: Takara Bio Revenue Shares, by Business Segment, Fiscal Year 2013a
Table 75: Takara Bio Revenue Shares, by Business Segment, Fiscal Year 2013a
Thermo Fisher Scientific, Inc.
Figure 14: Thermo Fisher Scientific Revenue Shares, by Region, 2013
Figure 15: Life Technologies Revenue Shares, by Region, 2012
Table 76: Thermo Fisher Scientific Revenue Shares, by Business Segments, 2013a
Toyobo Co., Ltd
Table 77: Toyobo Revenue Shares, by Business Segment, Fiscal Year 2013a

GLOSSARY

List of Tables

Table 1: Timeline of PCR Technology History (1983 – 2013)
Table 2: Timeline of Real-Time PCR History
Table 3: Timeline of Digital PCR History
Table 4: Some Important Factors to be Considered while Planning PCR Experiments
Table 5: Key Players and Their Products in the Field of Colony PCR
Table 6: Key Players and Their Products in the Field of Digital PCR
Table 7: Key Players and Their Products in the Field of Direct PCR
Table 8: Key Players and Their Products in the Field of Hot-Start PCR
Table 9: Key Players and Their Products in the Field of In Situ PCR
Table 10: Key Players and Their Products in the Field of Long PCR
Table 11: Key Players and Their Products in the Field of Long Accurate PCR
Table 12: Key Players and Their Products in the Field of Methylation-Specific PCR
Table 13: Key Players and Their Products in the Field of Multiplex PCR
Table 14: Key Players and Their Products in the Field of Nested PCR
Table 15: Key Players and Their Products in the Field of Quantitative Fluorescence PCR
Table 16: Key Players and Their Products in the Field of Random Amplified Polymorphic DNA PCR
Table 17: Commonly Used Detection Chemistries in Real-Time PCR
Table 18: Key Players and Their Products in the Field of Real-Time PCR
Table 19: Key Players and Their Products in the Field of Reverse Transcription PCR
Table 20: Key Players and Their Products in the Field of Single Cell PCR
Table 21: Key Players and Their Products in the Field of Universal Fast Walking PCR
Table 22: Key Players Offering PCR-Based Cancer Diagnostics Products in the Market
Table 23: Key Players Offering PCR-Based Diagnostics Products Targeting Human Infections
Table 24: Key Players Offering PCR-Based Pre-natal Diagnostics Products in the Market
Table 25: Common Commercial Systems Used for Food Pathogen Detection
Table 26: International Standards and Guidelines for Campylobacter spp. Identification
Table 27: Key Players Offering PCR-Based Kits to Detect Campylobacter and Its Subspecies
Table 28: International Standards and Guidelines for Escherichia coli Detection
Table 29: Key Players Offering PCR-Based kits to Detect Pathogenic Escherichia coli and Its Subspecies
Table 30: International Standards and Guidelines for Listeria Detection
Table 31: Key Players Offering PCR-Based kits to Detect Listeria monocytogenes and Its Subspecies
Table 32: International Standards and Guidelines for Salmonella Detection
Table 33: Key Players Offering PCR-Based kits to Detect Salmonella and Its Subspecies
Table 34: Key Players Offering PCR-Based kits to Detect Other Selected Food-Borne and Water-Borne Pathogens
Table 35: Key Players Offering PCR-Based Veterinary Diagnostics Products
Table 36: Key Players Offering PCR-Based Diagnostics Products Targeting Plant Infections
Table 37: Key Players Offering PCR-Based Kits to Detect GMO Foods/Plants in the Market
Table 38: Key Players Offering PCR-Based Kits to Detect Food Allergens and Animal Species in Food in the Market
Table 39: Key Players Offering PCR-Based Human Identity and Forensic Testing Products in the Market
Table 40: Key Players Offering Products for MicroRNA Analysis Involving PCR Technology
Table 41: Key Players Offering PCR-Based Mutations Detection Products
Table 42: Key Players Offering PCR-Based Products for SNPs Detection and Genotyping
Table 43: Key Players Offering PCR-Based Sequencing Products
Table 44: Key Players Offering NGS Library Quantification Products that Incorporate PCR Technology
Table 45: Key Players Offering PCR-Related Products for Genotyping/DNA Fingerprinting
Table 46: Key Players Offering PCR-Based Site-Directed Mutagenesis Products
Table 47: Basic PCR Patents Expired in 28 March 2005 in USA
Table 48: Key Patents in Selected PCR Market Segments and their Expiry Dates in USA
Table 49: Market Drivers of the European Union PCR Market
Table 50: Market Restraints of the European Union PCR Markets
Table 51: Key Mergers and Acquisitions during the Past Five Years Relevant in PCR Market (2010-2014)
Table 52: Global PCR Technology Markets, By Value (USD, Million)
Table 53: PCR Market Segments and their Growth Trends in Europe, By Value (USD, Million)
Table 54: Global PCR Technologies Demand by End-Use Segments, by Value (USD, Million)
Table 55: PCR Technologies Demand by End-Use Segments in Europe, by Value (USD, Million)
Table 56: Regulatory Agencies Responsible for Molecular Diagnostics in Europe
Table 57: Key Laws and Regulations Influencing PCR-based Medical Diagnostics Markets in Europe
Table 58: Main International Agencies Involved in Food Safety Aspects
Table 59: Selected Regulatory Agencies Responsible for Food Safety and GMO Testing in the EU
Table 60: Food Safety Laws and Regulations Influencing PCR Technologies Markets in the EU
Table 61: Selected Companies Enabling High Throughput in qPCR
Table 62: Comparison of the Reaction Formats of Selected Real-Time PCR Instruments in the Market
Table 63: Comparison of the Thermal Modules of Selected Commercial Real-Time PCR Systems
Table 64: Comparison of the Optical Modules of Selected Real-Time PCR Systems in the Market
Table 65: Technical Approaches Adopted for Limiting Off-Target Amplification in Multiplex qPCR Assays
Table 66: Fluorescence Chemistry and Multiplex Capability of Selected qPCR Systems in the Market
Table 67: Affymetrix Revenue Shares, by Business Unit, 2013
Table 68: Bio-Rad Laboratories Revenue Shares, by Segment, 2013
Table 69: Clinical and Non-Clinical Revenue Shares, 2013
Table 70: Roche Diagnostics – Main Businesses and their Revenues, 2013
Table 71: Selected PCR-Based Companion Diagnostics under Development by Roche
Table 72: Merck Millipore Revenue Shares, by Business Segments, 2013
Table 73: Geographic Distribution of QIAGEN Revenues, 2012-2013 (USD, Million)
Table 74: Main Business Units of Sigma-Aldrich and Their Revenue Shares, 2013
Table 75: Takara Bio Revenue Shares, by Business Segment, Fiscal Year 2013a
Table 76: Thermo Fisher Scientific Revenue Shares, by Business Segments, 2013a
Table 77: Toyobo Revenue Shares, by Business Segment, Fiscal Year 2013a

List of Figures

Figure 1: Market Shares and Forecasts of PCR Technology Market Segments
Figure 2: Market Shares and Forecasts of PCR Technologies Demand in Europe by End-Use Segments
Figure 3: Abbott Revenue Shares, by Business Segments, 2013
Figure 4: Affymetrix Revenue Shares, by Product Category, 2013
Figure 5: Agilent Technologies Revenue Shares, by Business Group, 2013
Figure 6: Bio-Rad Laboratories Revenue Shares, by Region, 2013
Figure 7: Cepheid Revenue Shares, by Region, 2013
Figure 8: Eppendorf Revenue Shares, by Region, 2013
Figure 9: Roche Diagnostics Revenue Shares, by Region, 2013
Figure 10: Merck Millipore Revenue Shares, by Region, 2013
Figure 11: Revenue Distribution by Customer Categories, QIAGEN, 2013
Figure 12: Revenue Shares of Sigma-Aldrich Business Units, by Region, 2013
Figure 13: Takara Bio Revenue Shares, by Business Segment, Fiscal Year 2013a
Figure 14: Thermo Fisher Scientific Revenue Shares, by Region, 2013
Figure 15: Life Technologies Revenue Shares, by Region, 2012

- ADNucleis
- Abacus Diagnostica Oy
- Abbott Laboratories
- Affymetrix, Inc.
- Agilent Technologies, Inc.
- AlphaHelix Molecular Diagnostics AB
- Altona Diagnostics GmbH
- Ampliqon A/S
- AnDiaTec GmbH & Co. KG
- Analytik Jena AG
- Ares Bioscience GmbH
- BIORON GmbH / BIORON Diagnostics GmbH
- BJS Biotechnlogies Ltd.
- Bibby Scientific Limited
- Bio-Rad Laboratories, Inc.
- BioCat GmbH
- BioGene Ltd.
- Biogazelle N.V.
- Bioline Reagents Limited
- Biolytix AG
- Biotools Biotechnological and Medical Laboratories S.A.
- CLONIT srl
- CONGEN Biotechnologie GmbH
- Cepheid, Inc.
- Devyser AB
- ELITech Group
- Ecoli s.r.o
- Enigma Diagnostics Limited
- Eppendorf AG
- Eurogentec S.A.
- Exiqon A/S
- F. Hoffmann-La Roche Ltd.
- Fluorogenics Ltd.
- G-Storm
- GENOMICA S.A.U.
- GeneON GmbH
- Genekam Biotechnology AG
- LGC Genomics Ltd.
- LIPSDIAG GmbH
- Labtech International Ltd.
- Merck Millipore International
- MoBiTec GmbH
- Multiplicom N.V.
- NimaGen B.V.
- PEQLAB Biotechnologie GmbH
- PathoFinder B.V.
- PrimerDesign Ltd.
- Promega Corporation
- QIAGEN N.V.
- STARLAB Switzerland
- Sacace Biotechnologies Srl
- Sigma-Aldrich Corporation
- Solis BioDyne
- TAG Copenhagen A/S
- Takara Bio, Inc.
- Thermo Fisher Scientific, Inc.
- Toyobo Co., Ltd
- bioMérieux S.A.
- biomers.net GmbH
- highQu GmbH
- inno-train Diagnostik GmbH

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