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Antibacterial Market Survey: Analyses and ForecastsTechnology, Sales and Company Profiles
ADIS, Nov 2002


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Over the past several years, infectious disease management has become an increasing challenge for practicing physicians. Management of bacterial infection has become difficult due to the emergence of drug-resistant bacteria. There has been an alarming increase in the number of resistant Gram-positive organisms over the last 5 years. These Gram-positive organisms include: Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecium, Enterococcus faecalis, and Streptococcus pneumoniae. Reports from several centralized agencies that follow bacterial resistance trends indicate that the prevalence of methicillin-resistant S. aureus (Mrsa) has increased from 25 to 37% and vancomycin-resistant E. faecium (VRE) from 35 to 65% in the last 3 years alone. These resistant organisms represent a major cause of morbidity and mortality in hospitalized patients with infections. The problem of resistant Gram-positive organisms is not limited to the hospitalized patient. Outpatients have also been affected with the emergence of penicillin-resistant S. pneumoniae (Prsp), a cause of community-acquired pneumonia.



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