Trafficking of GPCRs. Progress in Molecular Biology and Translational Science Volume 132

Table of Contents

1. Arrestins: Critical Players in Trafficking of Many GPCRs
   Vsevolod V. Gurevich and Eugenia V. Gurevich
2. Regulation of GPCR Trafficking by Ubiquitin
   Justine E. Kennedy and Adriano Marchese
3. Rhodopsin Trafficking and Mistrafficking: Signals, Molecular Components and Mechanisms
   Ina Nemet, Philip Ropelewski and Yoshikazu Imanishi
4. Intracellular Trafficking of Neuropeptide Y Receptors
   Karin Mörl and Annette G. Beck-Sickinger
5. Insights into Serotonin Receptor Trafficking: Cell Membrane Targeting and Internalization
   Michèle Darmon, Sana Al Awabdh , Michel-Boris Emerit  and Justine Masson 
6. Calcium-Sensing Receptor: Trafficking, Endocytosis, Recycling and Importance of    Interacting Proteins
   Kausik Ray
7. Trafficking of ß Adrenergic Receptors: Implications in Intracellular Receptor Signaling
   Qin Fu and Yang K. Xiang
8. Post-endocytic sorting of Adrenergic and Opioid Receptors: New Mechanisms and Functions.
   Shanna L. Bowman and Manojkumar A. Puthenveedu
9. a2 Adrenergic Receptor Trafficking as a Therapeutic Target in Antidepressant Drug Action
   Christopher Cottingham, Craig J. Ferryman and Qin Wang
10. Regulation of a2B-Adrenerigc Receptor Export Trafficking by Specific Motifs
    Guangyu Wu, Jason E. Davis and Maoxiang Zhang
11. Temperature-Sensitive Intracellular Traffic of ?2c-Adrenergic Receptor
    Catalin M. Filipeanu
12. N-Terminal Signal Peptides of G Protein-Coupled Receptors: Significance for Receptor Biosynthesis, Trafficking and Signal Transduction
    Claudia Rutz, Wolfgang Klein and Ralf Schülein
13. Regulation of GPCR Anterograde Trafficking by Molecular Chaperones and Motifs 
    Brent Young, Jaime Wertman and Denis J. Dupré
    

Authors

Guangyu Wu Georgia Regents University. Dr. Guangyu Wu, the editor of this book, is a professor in the Department of Pharmacology and Toxicology at the Medical College of Georgia, Georgia Regents University. The long term goal of Dr. Wu's research effort is to define the molecular mechanisms underlying the intracellular trafficking and signal propagation of GPCRs. Dr. Wu's research at the earlier stages, as a graduate student and a post-doctoral fellow, was mainly on the GPCR pharmacology and signal transduction pathways. Since starting his own laboratory in the Department of Pharmacology at Louisiana State University Health Sciences Center New Orleans, Dr. Wu has focused his research on the regulation of GPCR export from the endoplasmic reticulum through the Golgi apparatus to the cell surface through studying the function of well-defined transport machinery at different intracellular organelles and defining specific motifs embedded within the receptors that direct receptor export from the ER/Golgi or cell surface transport.