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Chronic Pain - Pipeline Review, H1 2015

  • ID: 3112053
  • February 2015
  • 344 pages
  • Global Markets Direct
1 of 4

FEATURED COMPANIES

  • AbbVie Inc.
  • AstraZeneca PLC
  • Cytogel Pharma, LLC
  • Johnson & Johnson
  • Moberg Pharma AB
  • Pfizer Inc.
  • MORE

Chronic Pain - Pipeline Review, H1 2015

Summary

This, ‘Chronic Pain - Pipeline Review, H1 2015’, provides an overview of the Chronic Pain’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Chronic Pain, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Chronic Pain and special features on late-stage and discontinued projects.

This report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from This proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by This team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes READ MORE >

Note: Product cover images may vary from those shown
2 of 4

FEATURED COMPANIES

  • AbbVie Inc.
  • AstraZeneca PLC
  • Cytogel Pharma, LLC
  • Johnson & Johnson
  • Moberg Pharma AB
  • Pfizer Inc.
  • MORE

List of Tables
List of Figures
Introduction
REPORT COVERAGE
Chronic Pain Overview
Therapeutics Development
Pipeline Products for Chronic Pain - Overview
Pipeline Products for Chronic Pain - Comparative Analysis
Chronic Pain - Therapeutics under Development by Companies
Chronic Pain - Therapeutics under Investigation by Universities/Institutes
Chronic Pain - Pipeline Products Glance
Late Stage Products
Clinical Stage Products
Early Stage Products
Unknown Stage Products
Chronic Pain - Products under Development by Companies
Chronic Pain - Products under Investigation by Universities/Institutes
Chronic Pain - Companies Involved in Therapeutics Development
AbbVie Inc.
Acadia Pharmaceuticals Inc.
Adynxx, Inc.
Akron Molecules AG
Allergan, Inc.
arGEN-X BV
Astellas Pharma Inc.
Astraea Therapeutics, LLC
AstraZeneca PLC
BCN Peptides, S.A.
BioDelivery Sciences International, Inc.
Bionomics Limited
Cara Therapeutics, Inc.
ChironWells GmbH
Chromocell Corporation
Collegium Pharmaceutical, Inc.
CoLucid Pharmaceuticals, Inc.
Convergence Pharmaceuticals Ltd.
Creabilis SA
Cytogel Pharma, LLC
Daewoong Pharmaceutical Co., Ltd.
Daiichi Sankyo Company, Limited
Dompe Farmaceutici S.p.A.
DURECT Corporation
Egalet Corporation
Eli Lilly and Company
Endo Pharmaceuticals Inc.
Glenmark Pharmaceuticals Ltd.
Grunenthal GmbH
Johnson & Johnson
Kareus Therapeutics, SA
Kineta, Inc.
Kymab Limited
Laboratorios Del Dr. Esteve S.A.
Lohocla Research Corporation
Merck & Co., Inc.
Mertiva AB
Mesoblast Limited
Moberg Pharma AB
Mundipharma International Limited
Nanomerics Ltd
Nektar Therapeutics
Neura Therapeutik, LLC
Nippon Shinyaku Co., Ltd.
Orion Oyj
Pain Therapeutics, Inc.
Pfizer Inc.
Phosphagenics Limited
Purdue Pharma L.P.
Relmada Therapeutics, Inc.
Rottapharm SpA
Santen Pharmaceutical Co., Ltd.
Sea4Us
Shionogi & Co., Ltd.
Signature Therapeutics, Inc
Snowdon Inc.
Syntrix Biosystems, Inc.
Teikoku Pharma USA, Inc.
Teva Pharmaceutical Industries Limited
Trevena, Inc.
UMeWorld Limited
Zynerba Pharmaceuticals, Inc.
Chronic Pain - Therapeutics Assessment
Assessment by Monotherapy Products
Assessment by Combination Products
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Drug Profiles
(celecoxib + tramadol hydrochloride) - Drug Profile
(oxycodone hydrochloride + naltrexone) ER - Drug Profile
A-836339 - Drug Profile
AAT-008 - Drug Profile
AGN-XX/YY - Drug Profile
AKR-201 - Drug Profile
APR-102 - Drug Profile
ARX-8203 - Drug Profile
ASP-7962 - Drug Profile
AXS-01 - Drug Profile
AXS-03 - Drug Profile
AYX-1 - Drug Profile
AYX-2 - Drug Profile
BBI-11008 - Drug Profile
bupivacaine hydrochloride - Drug Profile
buprenorphine hydrochloride - Drug Profile
buprenorphine hydrochloride depot - Drug Profile
buprenorphine hydrochloride ER - Drug Profile
cebranopadol - Drug Profile
celecoxib - Drug Profile
CNV-3000164 - Drug Profile
CNV-3000223 - Drug Profile
Conjugated Stigmine Program - Drug Profile
CR-701 - Drug Profile
CR-845 - Drug Profile
CRB-0022 - Drug Profile
CRB-0089 - Drug Profile
CT-340 - Drug Profile
Cyt-1010 - Drug Profile
DD-04107 - Drug Profile
dexmedetomidine hydrochloride - Drug Profile
DF-2593A - Drug Profile
Drugs for Chronic Pain and Inflammation - Drug Profile
Drugs for Chronic Pelvic Pain - Drug Profile
DS-1971 - Drug Profile
duloxetine hydrochloride DR - Drug Profile
DWJ-208 - Drug Profile
E-52862 - Drug Profile
Egalet-003 - Drug Profile
flurbiprofen - Drug Profile
FY-101C - Drug Profile
FY-103B - Drug Profile
GBR-900 - Drug Profile
Gene Therapy to Activate Endomorphin 2 for Chronic Pain - Drug Profile
Gene Therapy to Activate Mu Opioid Receptor for Chronic Pain - Drug Profile
GIBH-1014 - Drug Profile
grapiprant - Drug Profile
HS-731 - Drug Profile
hydrocodone bitartrate - Drug Profile
hydrocodone bitartrate ER - Drug Profile
hydrocodone bitartrate ER - Drug Profile
hydrocodone bitartrate ER - Drug Profile
hydromorphone hydrochloride - Drug Profile
Kindolor - Drug Profile
KY-1017 - Drug Profile
LEVI-04 - Drug Profile
levorphanol tartrate ER - Drug Profile
lexanopadol - Drug Profile
mirogabalin - Drug Profile
Monoclonal Antibodies for Chronic Pain - Drug Profile
Monoclonal Antibodies to Block Nav1.7 for Chronic Pain - Drug Profile
morphine sulfate ER - Drug Profile
MPC-06ID - Drug Profile
NET-END - Drug Profile
NKTR-181 - Drug Profile
NL-001 - Drug Profile
NL-002 - Drug Profile
NM-0127 - Drug Profile
Omnitram - Drug Profile
onabotulinumtoxin A - Drug Profile
OSX-300 - Drug Profile
OSX-300 Backups - Drug Profile
oxycodone ER - Drug Profile
oxycodone hydrochloride ER - Drug Profile
oxycodone hydrochloride ER - Drug Profile
oxycodone hydrochloride ER - Drug Profile
oxycodone hydrochloride ER - Drug Profile
oxymorphone hydrochloride - Drug Profile
oxymorphone hydrochloride ER - Drug Profile
palmidrol - Drug Profile
Peptide to Block Calcium Channel for CNS Disorders - Drug Profile
Peptides to Inhibit Ion Channel for Chronic Pain - Drug Profile
PF-05089771 - Drug Profile
PF-06372865 - Drug Profile
PF-329 - Drug Profile
PF-6129 - Drug Profile
PF-614 - Drug Profile
PFR-03088 - Drug Profile
PFR-03318 - Drug Profile
PFR-03321 - Drug Profile
PFR-03323 - Drug Profile
PFR-03325 - Drug Profile
PFR-06158 - Drug Profile
PFR-06177 - Drug Profile
PRC-062 - Drug Profile
Prostatic Acid Phosphatase - Drug Profile
PTI-202 - Drug Profile
PTI-721 - Drug Profile
SA-14867 - Drug Profile
Small Molecule Agonizing ER-Beta for Neurology and Pain - Drug Profile
Small Molecule for Central Nervous System - Drug Profile
Small Molecule for Chronic Pain - Drug Profile
Small Molecule for Neuropathic Pain and Inflammatory Pain - Drug Profile
Small Molecule to Agonize mGlu2/3 for Chronic Pain - Drug Profile
Small Molecule to Antagonize TRPA1 for Chronic Pain - Drug Profile
Small Molecule to Block Cav2.2 Channel for Chronic Pain - Drug Profile
Small Molecule to Inhibit ASK-1 for Chronic Pain - Drug Profile
Small Molecule to Inhibit GPR-84 for Chronic Pain - Drug Profile
Small Molecule to Inhibit mPGES-1 for Chronic Pain - Drug Profile
Small Molecule to Inhibit P2Y14 for Chronic Pain - Drug Profile
Small Molecule to Modulate Ion Channel for Chronic Pain - Drug Profile
Small Molecules to Activate KCNQ Channels for Chronic Pain and CNS disorder - Drug Profile
Small Molecules to Activate Mu Opioid Receptor for Chronic Pain - Drug Profile
Small Molecules to Agonize NOP for Pain - Drug Profile
Small Molecules to Antagonize NMDA Receptor and CHRNA7 for CNS - Drug Profile
Small Molecules to Antagonize P2X3 for Chronic Pain - Drug Profile
Small Molecules to Antagonize Tyrosine Kinase Receptor A for Chronic Pain - Drug Profile
Small Molecules to Block Cav2.2 Channel for Chronic Pain - Drug Profile
Small Molecules to Block Cav2.2 Channel for Chronic Pain - Drug Profile
Small Molecules to Block HCN1 Channel for Chronic Neuropathic Pain - Drug Profile
Small Molecules to Block Nav 1.7 Channels for Chronic And Neuropathic Pain - Drug Profile
Small Molecules to Block Nav1.7 for Pain - Drug Profile
Small Molecules to Block TRPA1 and TRPV1 for CNS - Drug Profile
Small Molecules to Block TRPV1 for Chronic and Neuropathic Pain - Drug Profile
SND-121 Prodrug - Drug Profile
sufentanil citrate - Drug Profile
Synthetic Peptide to Inhibit CRMP-2 Protein for Pain - Drug Profile
tapentadol hydrochloride - Drug Profile
tramadol hydrochloride SR - Drug Profile
TROX-1 - Drug Profile
TRV-734 - Drug Profile
U-2902 - Drug Profile
UMB-425 - Drug Profile
V-116517 - Drug Profile
VLNX-4975 - Drug Profile
YYC-301 - Drug Profile
ZEP-3 - Drug Profile
ZYN-001 - Drug Profile
Chronic Pain - Recent Pipeline Updates
Chronic Pain - Dormant Projects
Chronic Pain - Discontinued Products
Chronic Pain - Product Development Milestones
Featured News & Press Releases
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer

List of Tables
Number of Products under Development for Chronic Pain, H1 2015
Number of Products under Development for Chronic Pain - Comparative Analysis, H1 2015
Number of Products under Development by Companies, H1 2015
Number of Products under Development by Companies, H1 2015 (Contd..1)
Number of Products under Development by Companies, H1 2015 (Contd..2)
Number of Products under Development by Companies, H1 2015 (Contd..3)
Number of Products under Development by Companies, H1 2015 (Contd..4)
Number of Products under Development by Companies, H1 2015 (Contd..5)
Number of Products under Investigation by Universities/Institutes, H1 2015
Comparative Analysis by Late Stage Development, H1 2015
Comparative Analysis by Clinical Stage Development, H1 2015
Comparative Analysis by Early Stage Development, H1 2015
Comparative Analysis by Unknown Stage Development, H1 2015
Products under Development by Companies, H1 2015
Products under Development by Companies, H1 2015 (Contd..1)
Products under Development by Companies, H1 2015 (Contd..2)
Products under Development by Companies, H1 2015 (Contd..3)
Products under Development by Companies, H1 2015 (Contd..4)
Products under Development by Companies, H1 2015 (Contd..5)
Products under Development by Companies, H1 2015 (Contd..6)
Products under Development by Companies, H1 2015 (Contd..7)
Products under Investigation by Universities/Institutes, H1 2015
Chronic Pain - Pipeline by AbbVie Inc., H1 2015
Chronic Pain - Pipeline by Acadia Pharmaceuticals Inc., H1 2015
Chronic Pain - Pipeline by Adynxx, Inc., H1 2015
Chronic Pain - Pipeline by Akron Molecules AG, H1 2015
Chronic Pain - Pipeline by Allergan, Inc., H1 2015
Chronic Pain - Pipeline by arGEN-X BV, H1 2015
Chronic Pain - Pipeline by Astellas Pharma Inc., H1 2015
Chronic Pain - Pipeline by Astraea Therapeutics, LLC, H1 2015
Chronic Pain - Pipeline by AstraZeneca PLC, H1 2015
Chronic Pain - Pipeline by BCN Peptides, S.A., H1 2015
Chronic Pain - Pipeline by BioDelivery Sciences International, Inc., H1 2015
Chronic Pain - Pipeline by Bionomics Limited, H1 2015
Chronic Pain - Pipeline by Cara Therapeutics, Inc., H1 2015
Chronic Pain - Pipeline by ChironWells GmbH, H1 2015
Chronic Pain - Pipeline by Chromocell Corporation, H1 2015
Chronic Pain - Pipeline by Collegium Pharmaceutical, Inc., H1 2015
Chronic Pain - Pipeline by CoLucid Pharmaceuticals, Inc., H1 2015
Chronic Pain - Pipeline by Convergence Pharmaceuticals Ltd., H1 2015
Chronic Pain - Pipeline by Creabilis SA, H1 2015
Chronic Pain - Pipeline by Cytogel Pharma, LLC, H1 2015
Chronic Pain - Pipeline by Daewoong Pharmaceutical Co., Ltd., H1 2015
Chronic Pain - Pipeline by Daiichi Sankyo Company, Limited, H1 2015
Chronic Pain - Pipeline by Dompe Farmaceutici S.p.A., H1 2015
Chronic Pain - Pipeline by DURECT Corporation, H1 2015
Chronic Pain - Pipeline by Egalet Corporation, H1 2015
Chronic Pain - Pipeline by Eli Lilly and Company, H1 2015
Chronic Pain - Pipeline by Endo Pharmaceuticals Inc., H1 2015
Chronic Pain - Pipeline by Glenmark Pharmaceuticals Ltd., H1 2015
Chronic Pain - Pipeline by Grunenthal GmbH, H1 2015
Chronic Pain - Pipeline by Johnson & Johnson, H1 2015
Chronic Pain - Pipeline by Kareus Therapeutics, SA, H1 2015
Chronic Pain - Pipeline by Kineta, Inc., H1 2015
Chronic Pain - Pipeline by Kymab Limited, H1 2015
Chronic Pain - Pipeline by Laboratorios Del Dr. Esteve S.A., H1 2015
Chronic Pain - Pipeline by Lohocla Research Corporation, H1 2015
Chronic Pain - Pipeline by Merck & Co., Inc., H1 2015
Chronic Pain - Pipeline by Mertiva AB, H1 2015
Chronic Pain - Pipeline by Mesoblast Limited, H1 2015
Chronic Pain - Pipeline by Moberg Pharma AB, H1 2015
Chronic Pain - Pipeline by Mundipharma International Limited, H1 2015
Chronic Pain - Pipeline by Nanomerics Ltd, H1 2015
Chronic Pain - Pipeline by Nektar Therapeutics, H1 2015
Chronic Pain - Pipeline by Neura Therapeutik, LLC, H1 2015
Chronic Pain - Pipeline by Nippon Shinyaku Co., Ltd., H1 2015
Chronic Pain - Pipeline by Orion Oyj, H1 2015
Chronic Pain - Pipeline by Pain Therapeutics, Inc., H1 2015
Chronic Pain - Pipeline by Pfizer Inc., H1 2015
Chronic Pain - Pipeline by Phosphagenics Limited, H1 2015
Chronic Pain - Pipeline by Purdue Pharma L.P., H1 2015
Chronic Pain - Pipeline by Relmada Therapeutics, Inc., H1 2015
Chronic Pain - Pipeline by Rottapharm SpA, H1 2015
Chronic Pain - Pipeline by Santen Pharmaceutical Co., Ltd., H1 2015
Chronic Pain - Pipeline by Sea4Us, H1 2015
Chronic Pain - Pipeline by Shionogi & Co., Ltd., H1 2015
Chronic Pain - Pipeline by Signature Therapeutics, Inc, H1 2015
Chronic Pain - Pipeline by Snowdon Inc., H1 2015
Chronic Pain - Pipeline by Syntrix Biosystems, Inc., H1 2015
Chronic Pain - Pipeline by Teikoku Pharma USA, Inc., H1 2015
Chronic Pain - Pipeline by Teva Pharmaceutical Industries Limited, H1 2015
Chronic Pain - Pipeline by Trevena, Inc., H1 2015
Chronic Pain - Pipeline by UMeWorld Limited, H1 2015
Chronic Pain - Pipeline by Zynerba Pharmaceuticals, Inc., H1 2015
Assessment by Monotherapy Products, H1 2015
Assessment by Combination Products, H1 2015
Number of Products by Stage and Target, H1 2015
Number of Products by Stage and Mechanism of Action, H1 2015
Number of Products by Stage and Route of Administration, H1 2015
Number of Products by Stage and Molecule Type, H1 2015
Chronic Pain Therapeutics - Recent Pipeline Updates, H1 2015
Chronic Pain - Dormant Projects, H1 2015
Chronic Pain - Dormant Projects (Contd..1), H1 2015
Chronic Pain - Dormant Projects (Contd..2), H1 2015
Chronic Pain - Dormant Projects (Contd..3), H1 2015
Chronic Pain - Dormant Projects (Contd..4), H1 2015
Chronic Pain - Dormant Projects (Contd..5), H1 2015
Chronic Pain - Dormant Projects (Contd..6), H1 2015
Chronic Pain - Discontinued Products, H1 2015
Chronic Pain - Discontinued Products (Contd..1), H1 2015

List of Figures
Number of Products under Development for Chronic Pain, H1 2015
Number of Products under Development for Chronic Pain - Comparative Analysis, H1 2015
Number of Products under Development by Companies, H1 2015
Number of Products under Investigation by Universities/Institutes, H1 2015
Comparative Analysis by Late Stage Development, H1 2015
Comparative Analysis by Clinical Stage Development, H1 2015
Comparative Analysis by Early Stage Products, H1 2015
Assessment by Monotherapy Products, H1 2015
Assessment by Combination Products, H1 2015
Number of Products by Top 10 Targets, H1 2015
Number of Products by Stage and Top 10 Targets, H1 2015
Number of Products by Top 10 Mechanism of Actions, H1 2015
Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015
Number of Products by Top 10 Routes of Administration, H1 2015
Number of Products by Stage and Top 10 Routes of Administration, H1 2015
Number of Products by Top 10 Molecule Types, H1 2015
Number of Products by Stage and Top 10 Molecule Types, H1 2015

Note: Product cover images may vary from those shown
3 of 4

AbbVie Inc.
Acadia Pharmaceuticals Inc.
Adynxx, Inc.
Akron Molecules AG
Allergan, Inc.
arGEN-X BV
Astellas Pharma Inc.
Astraea Therapeutics, LLC
AstraZeneca PLC
BCN Peptides, S.A.
BioDelivery Sciences International, Inc.
Bionomics Limited
Cara Therapeutics, Inc.
ChironWells GmbH
Chromocell Corporation
Collegium Pharmaceutical, Inc.
CoLucid Pharmaceuticals, Inc.
Convergence Pharmaceuticals Ltd.
Creabilis SA
Cytogel Pharma, LLC
Daewoong Pharmaceutical Co., Ltd.
Daiichi Sankyo Company, Limited
Dompe Farmaceutici S.p.A.
DURECT Corporation
Egalet Corporation
Eli Lilly and Company
Endo Pharmaceuticals Inc.
Glenmark Pharmaceuticals Ltd.
Grunenthal GmbH
Johnson & Johnson
Kareus Therapeutics, SA
Kineta, Inc.
Kymab Limited
Laboratorios Del Dr. Esteve S.A.
Lohocla Research Corporation
Merck & Co., Inc.
Mertiva AB
Mesoblast Limited
Moberg Pharma AB
Mundipharma International Limited
Nanomerics Ltd
Nektar Therapeutics
Neura Therapeutik, LLC
Nippon Shinyaku Co., Ltd.
Orion Oyj
Pain Therapeutics, Inc.
Pfizer Inc.
Phosphagenics Limited
Purdue Pharma L.P.
Relmada Therapeutics, Inc.
Rottapharm SpA
Santen Pharmaceutical Co., Ltd.
Sea4Us
Shionogi & Co., Ltd.
Signature Therapeutics, Inc
Snowdon Inc.
Syntrix Biosystems, Inc.
Teikoku Pharma USA, Inc.
Teva Pharmaceutical Industries Limited
Trevena, Inc.
UMeWorld Limited
Zynerba Pharmaceuticals, Inc.

Note: Product cover images may vary from those shown
4 of 4
Note: Product cover images may vary from those shown

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