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World Pharmacogenomics — Future of Healthcare Industry 2009™


Description: The study on World Pharmacogenomics — Future of Healthcare Industry 2009™ includes the identification of novel genomic targets for drug development, the clinical applications of genomics science, potential benefits of pharmacogenomics, effect of genetic variability on drug toxicity and efficacy.

Importantly, this market research report integrate new developments in genomics and proteomics to clinical medicine, pharmacology, and therapeutics and assess the trends, developments and challenges that the industry faces.


Contents: 1. ASSESSING PHARMACOGENOMICS TECHNOLOGY AND PHARMACEUTICAL INDUSTRY
1.1. THE PHARMACEUTICAL INDUSTRY TODAY
1.2. BLOCKBUSTER DRUG SALES BY PHARMACEUTICAL SECTOR (2005)
1.3. COST OF DRUG DISCOVERY AND PHARMACOGENOMICS
1.4. FUTURE OF PHARMACOGENOMICS IN DRUG DEVELOPMENT

2. GLOBAL MARKET FOR PHARMACOGENOMICS DEVICES AND DIAGNOSTIC TOOLS
2.1. MARKET FOR MICROARRAYS (2004-2009)
2.1.1 Types of Microarrays
2.1.1.1 Nanochip Arrays
2.1.1.2 Bead Arrays
2.1.1.3 Nanoparticles Arrays
2.1.2 Market Demand for Microarrays in Pharmacogenomics
2.2. MARKET FOR PCR ARRAYS (2004-2009)
2.2.1 Types of PCR Array Technologies
2.2.1.1 LightCycler
2.2.1.2 TaqMan Technology
2.2.1.3 Invader
2.2.1.4 ReadIt Depolymerixation Assay
2.2.1.5 Tag-It Mutation Assay
2.2.2 Market Demand for PCR-Assays (2004-2009)
2.3. IN SITU ANALYSIS

3. DEMAND FOR PHARMACOGENOMICS TREATMENT, BY DISEASE APPLICATIONS (2004-2009)
3.1. CARDIOVASCULAR DISEASE
3.2. BREAST CANCER
3.3. LEUKEMIA
3.4. HIV/AIDS
3.5. GENETIC RESISTANCE TESTING AND PHARMACOGENOMICS

4. PHARMACOGENOMICS PATENT ANALYSIS AND IPO
4.1. PHARMACOGENOMICS PATENTS, BY APPLICATION CATEGORY
4.2. PHARMACOGENOMICS PATENTS, BY DISEASE
4.3. PHARMACOGENOMICS PATENTS, BY REGIONAL DISTRIBUTION

5. PHARMACOGENOMICS RESEARCH AND APPLICATION, BY REGION
5.1. UNITED STATES
5.2. EUROPEAN UNION
5.3. JAPAN
5.4. OTHER REGIONS

6. PHARMACOGENOMICS AND DRUG METABOLISM
6.1. DRUG METABOLISM BY CYTOCHROMES
6.2. P-450 ISOZYMES AND PHARMACEUTICALS
6.2.1 P450 Isozyme CYP3A
6.2.2 P450 Isozyme CYP2D6
6.2.3 P450 Isozyme CYP2C9
6.2.4 P450 Isozyme 2C19
6.2.5 P450 Isozyme 1A2
6.3. GLOBAL MARKET FOR AMPLICHIP ARRAYS
6.4. COMPETITION WITH PHENOTYPIC ASSAY

7. COMPANY PROFILES
7.1. AFFYMETRIX INC.
7.1.1 Sales Revenue by Region and Product Type, 2005
7.1.2 Research and Development Expenses
7.1.3 New Products Launches and Issues
7.2. AGILENT TECHNOLOGIES, INC.
7.2.1 Sales and Revenue, By Region and Types of Products 2004
7.2.2 Research And Development Expenses
7.2.3 New Product Launches and Initiatives
7.3. THIRD WAVE TECHNOLOGIES, INC
7.3.1 Sales and Revenue, By Region and Product Type 2004
7.3.2 Research and Development Revenues
7.3.3 Products Launches and Initiatives
7.4. NANOGEN INC.
7.4.1 Sales and Revenue, by Region and Product Type, 2004
7.4.2 Research and Development Revenues
7.4.3 Product Launches and Initiatives
7.5. OTHER COMPETITORS
7.5.1 Applied Biosystems
7.5.2 GE Healthcare
7.5.3 Sequenom Inc.
7.5.4 Molecular Devices Corporation
7.5.5 Illumina
7.5.6 Incyte Corporation
7.5.7 deCODE genetics, Inc.
7.5.8 Caliper Life Sciences
7.5.9 Orchid BioSciences, Inc.
7.5.10 Beckman Coulter, Inc.
7.5.11 Quest Diagnostics Incorporated

List of Tables:
Table 1:1 - Blockbuster Drug Sales, By Major Pharmaceutical Companies, 2004
Table 2:1 - World Market For Microarrays In Pharmacogenomics By Type, Through 2009 (Aagr %Age)
Table 2:2: World Market For Pcr-Assays, By Type, 2001-2009 (Aagr %Age)
Table 2:3 - World Market For In Situ, By Type, 2001-2009 (Aagr %Age)
Table 3:1 - Total Number Of Cardiovascular Cases Diagnosed And Reported Death, 2005
Table 3:2 - Leading Products In 2004 By Global Pharmaceutical Sales
Table 3:3 - World Gleevec Market Value, By Region, In Million Dollars, 2001-2009
Table 3:4 - Market For Hiv Resistance Testing Worldwide, By Region, (Aagr %Age) 2003-2009
Table 6:1 - World Market For Amplichip-Assays, By Type, 2001-2009 (Aagr %Age)
Table 7:1 - Affymetrix Inc. Sales Revenue By Region And Product Type, 2004
Table 7:2 - Research Revenue, For Three Months Ended September 30, 2004-2005, In Millions
Table 7:3 - Agilent Technologies Inc., Sales Revenue By Region And Product Type, 2004
Table 7:4 - Research Revenue, For Three Months Ended July 31, 2004-2005, In Millions
Table 7:5 - Third Wave Technologies., Sales Revenue By Region And Product Type, 2004
Table 7:6 - Third Wave Technologies Research Revenue, For Three Months Ended September 31, 2004-2005, In Millions
Table 7:7 - Nanogen Sales Revenue By Region And Product Type, 2004
Table 7:8 - Nanogen Research Revenue, For Three Months Ended September31, 2004-2005, In Millions

List of Figures:
Figure 1:1 - Total Pharmaceutical Excipients Market Revenue, In %Age, 2004-2008
Figure 1:2 - Cost Of Developing New Drugs, In Percentage, 2005
Figure 1:3 - Attrition Rates Of New Compounds In The Drug Development Processes, In %Age, 2004
Figure 1:4 - How Pharmacogenomics Can Streamline Future Clinical Trials
Figure 2:1 - Demand For Pharmacogenomics Diagnostic Tools Worldwide, By Type, 2004-2009
Figure 2:2: World Biochips Market, In Billion Dollars, 2001-2009
Figure 2:3 - World Market For Microarrays In Pharmacogenomics By Type, In ($Million), 2001-2009
Figure 2:4 - World Market For Pcr-Assays In Pharmacogenomics By Type, In ($Million), 2001-2009
Figure 3:1 - Number Of Cardiovascular Death, By Gender (Deaths Per 100,000 Population), 2000-2005
Figure 3:2 - World Statin Market Value, In Billion Dollars, 2005-2009
Figure 3:3 - Estimated Breast Cancer Cases/Deaths Worldwide, By Region, Per 100, 000 Population (2000-2004)
Figure 3:4 - World Market For Herceptin, By Region, ($ Millions), 2001-2009
Figure 3:5 - Leukemia Survival Rates, By Type, In Percentage Change, 2005
Figure 3:6- Regional Statistics For Hiv & Aids, End Of 2005, In Millions
Figure 3:7-Market For Hiv Resistance Testing Worldwide, By Region, ($ Million) 2003-2009
Figure 4:1-Number Of Pharmacogenomics Patents Filed And %Age Share, By Technology – 2005
Figure 4:2-Number Of Patents Application Filed, By Disease Target, 2005
Figure 4:3-Total Pharmacogenomics Patents By Assignee, January 2004- January 2005
Figure 4:4-Number Of Patents Filed, By Region (In Percentage), 2005
Figure 6:1-Drug Metabolism Enzymes And Frequency Of Their Mutations In Ethnic Population
Figure 6:2-Major Cytochrome P450 Isozymes
Figure 6:3-Global Market For Amplichip Arrays In Diagnostic Use By Region, Through 2009 ($ Millions)


Summary: Chapter – I: Assessing Pharmacogenomics Technology and Healthcare
- An Overview on the changing pharmacogenomics market over the period of 10 years
- How the recent pharmaceutical industry and businesses are shaping up?
- Listing of Sales of Blockbuster Drug by pharmaceutical companies, 2005
- How the costs of new drugs are assessed? Attrition rates of new Compounds in the Drug Development Processes?
- What is the future of Pharmacogenomics in Drug Development Processes?
- Study on how Pharmacogenomics Research streamline future drug discovery

Chapter – II: Global Market for Pharmacogenomics Devices and Application
- Demand for Pharmacogenomics Diagnostic Tools Worldwide
- Key Factors that contributed to the growth for Pharmacogenomics demand
- Types and Uses of Microarrays and Demand Analysis for Microarrays in Pharmacogenomics research
- Demand Analysis for Biochips Arrays in MEMS sector
- World Market For PCR-Assays and usage in Pharmacogenomics Research
- Study of In-situ, PCR and Microarrays in Pharmacogenomics

Chapter – III: Demand for Pharmacogenomics Treatment, by Applications - 2009
- Examining the role of Pharmacogenomics in specific disease application
- Statistical analysis of total number of Cardiovascular Death, by Gender and reported cases
- Market Demand for Statin, Lipitor and Zucor Drugs
- Pharmacogenomics and Breast Cancer Treatment, estimated number of cases and demand for Nerceptin
- Leukemia Survival Rates and Pharmacogenomics
- Pharmacogenomics in HIV/AIDS Treatment
- Genetic Resistance Testing and Pharmacogenomics
- Market For HIV Resistance Testing Worldwide, by million-dollar usage.

Chapter – IV: Patents And Commercialization Issues
- Estimation of Total Patents filed (2004-2006)
- Number of Patents Application filed, by Disease Target
- Total Pharmacogenomics Patents By Assignee
- Number of Patents Filed, by Region

Chapter – V: Pharmacogenomics Research and Application, By Region

Chapter – VI: Pharmacogenomics and Drug Metabolism
- A Study on the Drug Metabolism Enzymes and Mutation Frequency
- Study of Drug Metabolism by Types and Enzymes (Cyctochromes, P-450, P450 Izyomes, Isozyme CPY2D6, CPY2C9, 2C19
- Market Demand for Ampliclips and Application
- Global Market For Amplichip Arrays In Diagnostic Use By Region

Chapter – VII: Major Company Profiles and Research

Chapter – VIII: Appendices


Companies Mentioned - Affymetrix Inc. - Agilent Technologies, Inc. - Third Wave Technologies, Inc - Nanogen Inc. - Applied Biosystems - GE Healthcare - Sequenom Inc. - Molecular Devices Corporation - Illumina - Incyte Corporation - deCODE genetics, Inc. - Caliper Life Sciences - Orchid BioSciences, Inc. - Beckman Coulter, Inc. - Quest Diagnostics Incorporated


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