Drug Targets for Breast Cancer - Market Research Reports - Research and Markets

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Drug Targets for Breast Cancer

Description:

Breast Cancer treatment is undergoing major transition. New targeted therapies are emerging that target cancer cells and spare healthy cells, resulting in reduced side effects. These developments have arisen following at least two decades of research into the molecular mechanisms that underlie cancer phenotypes.

This Drug Targets for Breast Cancer Report seeks to explore and systematically analyze both drug targets and associated therapeutics in current clinical development relating to breast cancer. Four major classes of breast cancer therapeutics are a particular focus - endocrine therapy, 'innovative' therapy, immunotherapy and chemotherapy. Several of the mainstream technologies utilized in breast cancer drug discovery are explored. Additionally, the therapeutic and market potential of each therapy type is investigated. This Report includes an up to date review of pipeline and market developments in the breast cancer therapeutics field.

Questions Answered

- Who is currently developing breast cancer therapeutics?
- What are the key drug targets that underlie such developments and which have the most therapeutic and commercial potential?
- How is breast cancer treatment changing?
- What are the relative merits of approved breast cancer therapeutics?
- What are the competitive advantages of new-generation breast cancer drugs?
- Where are the main challenges in breast cancer drug development?
- Are there any breast cancer patient sub-groups presently underserved by current and emerging therapies?
- Where are the opportunities relating to breast cancer drug development?
- What are the future prospects for breast cancer therapeutics?

Key Reasons to Purchase

- Determine what is new in breast cancer therapeutics by review of clinical developments in current pharmaceutical pipelines.
- Assess the therapeutic potential of breast cancer therapeutics by understanding the underlying drug targets and technology that that have facilitated drug development
- Assess the market potential of breast cancer therapeutics from maps of the current market landscape, an evaluation of the success of approved breast cancer therapeutics, and consideration of relevant future market projections.
- Get an up-to-date perspective on breast cancer drug development with a systematic review of each breast cancer therapy type
- Identify the key technological platforms currently utilized in breast cancer drug discovery.
- Look inside 15 companies involved in breast cancer drug discovery, including their product pipelines, financial standing, partnerships & alliances, and more
- Obtain a current industry snapshot of breast cancer drug discovery from a short survey conducted in parallel with the writing of this report.
- Gain insight into current challenges in breast cancer drug discovery through in-depth interviews with four industry experts.

Market Opportunities

There are approximately 50 breast cancer drugs in current development. Each of the four drug therapy categories identified in this report are witnessing significant developments. Market opportunities in this space include:

- Invest in basic research to establish a sound knowledge base on emerging breast cancer drug targets and their associated biology
- Develop model systems for clinical investigation of breast cancer to broaden applicability of breast cancer therapeutics and simplify clinical development.
- Develop technology platforms for development of targeted therapies with reduced side effects.
- Develop diagnostic tests for use with new therapies so that treatment regimes can be tailored for a specific patient.
- Investigate the possibility of cross-indications of breast cancer therapeutics to increase therapeutic value.
- Focus on breast cancer patient sub-groups that represent highest areas of unmet medical needs

Contents:

1 Executive Summary
Breast Cancer
Breast Cancer Therapeutics
Breast Cancer Targets
Breast Cancer Technologies
Breast Cancer Markets
Future Perspectives and Breast Cancer

2 Introduction
Current Needs and Breast Cancer Therapeutics
Breast Cancer Epidemiology
Breast Cancer Treatment and Historical Milestones
Breast Cancer Types
Causes and Risk Factors
Diagnostics, Biomarkers and Genetics
Awareness and Education
Breast Cancer Treatment
Breast Cancer Drug Targets and Therapeutics
Objectives and Scope

3 Targets and Therapeutics in Breast Cancer Endocrine Therapy
Introduction
Estrogen and the Estrogen Receptor
Estrogen, The Estrogen Receptor and Breast Cancer
Approved and Emerging Pipeline Endocrine Therapies
Combination Endocrine Therapies

4 Targets and Therapeutics in Breast Cancer 'Innovative' Therapy
Introduction
Targeting Growth Factors
Targeting Angiogenesis
Targeting Farnesylation
Targeting the MEK Pathway
Targeting the mTOR Pathway
Targeting Apoptosis
Targeting DNA Synthesis and Repair
Targeting the Proteosome

5 Targets and Therapeutics in Breast Cancer Immunotherapy
Breast Cancer Vaccines
Adjuvants in Breast Cancer Vaccines
Monoclonal Antibodies

6 Targets and Therapeutics in Breast Cancer Chemotherapy
Introduction
Historical Timeline
Approved Breast Cancer Chemotherapy
Emerging Breast Cancer Chemotherapy
Combination Therapy

7 Technology and Breast Cancer
Gene Cloning and Characterization
Functional Genomics and RNAi
Gene Arrays
Diagnostics and Biomarkers
Population Genetics
Drug Delivery

8 The Breast Cancer Market
The Market Landscape
Endocrine Therapies
Innovative Therapies
Immunotherapy
Chemotherapy

9 Future Perspectives
R&D Challenges
Opportunities
Breast cancer treatment of the future
Breast cancer patients

10 Company Profiles: Agendia, AstraZeneca, Genentech, Therion Biologics, Dendreon, American Pharmaceutical Partners, ViRexx, Bristol Myers Squibb, Novartis

11 Interviews

Companies Mentioned

- Agendia - AstraZeneca - Genentech - Therion Biologics - Dendreon - American Pharmaceutical Partners - ViRexx - Bristol Myers Squibb - Novartis

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