Contents:

POC MANUFACTURERS 3M Medical Diagnostics Products Agreements Abaxis Clinical Chemistry Analyser Agreements Research and Development Financials Revenue by Geographic Region, Fiscal 2007 Revenue by Product Category, Fiscal 2007 Abbott Diagnostics i-STAT 1 Agreements Financials Abbott Diagnostics – Product Sales, 2004-2006 Accumetrics Platelet Function Analysers ACRONGENOMICS BioLED Technology Agreements Aerscher Diagnostics HemaPrompt and HemaPrompt FG Alfa Scientific Designs Instant-View Drug Screen Tests Agreements AMDL DR-70 Combination Immunogene Therapy (CIT) Amnisure International AmniSure PROM Test Litigation Analyte Works Ltd POC Theranostics Arkray POC Clinical Chemistry Electrolyte Analyser Blood Ammonia Meter Urinalysis AT First Diagnostic FirstVue inSTIcheck Audit Diagnostics Liqui-Stat Wet Chemistry POC System Hb-Stat Axis-Shield Instruments Diabetes Tests Inflammation Tests Coagulation Tests Afinion Pipeline Short-Term Agreements Financials Point-of-Care Sales Analysis (£ thousand) British Biocell International BBI Enzymes Agreements BD Diagnostics Flu Tests Respiratory Syncytial Virus TestsMeningitis Tests Strep A Tests H. pylori C.difficile Vaginitis Test BD GeneOhm Products Acquisitions New Chinese Manufacturing Plant for Rapid Diagnostic Products Financials Operating Results by Division, 2003-2006 (US$ million)* Beckman Coulter Physician Office Instruments Rapid Test Kits for Primary Care Pregnancy Tests Infectious Disease Tests Acquisitions Financials bioLytical Laboratories IDE Study for INSTI kit Comparison of HIV-Test Products Biomerica Home Diagnostic Products Pregnancy Tests Financials BioMérieux Rapid Tests Cardiovascular Critical Care Agreements Equity Investment Divestments Financials Restructuring Strategic Plan 2007–2012 Income Statement, 2005-2006 Breakdown of Sales, 2005-2006, EUR million Bio-Rad Laboratories Diabetes Monitoring Drugs-of-abuse Testing HIV Tests Acquisitions Supply Agreement Financials BioSafe Self-Testing Kits Branan Medical Drugs-of-Abuse Testing Agreements CARE Products Professional Tests Home Use Chembio Diagnostics HIV Research and Development Agreements Financials CHEMPAQ Chempaq XBC Church & Dwight First Response Early Result Pregnancy Test First Response Easy-Read Ovulation Predictor Test Answer Pregnancy and Ovulation Tests Agreements Clinical Data Inc Clinical Chemistry Coagulation Analyser Diagnostic Test Group (RAC Medical) FOB Testing Strep A Pregnancy H.pylori Follicle Stimulating Hormone Urine Test Infectious Mononucleosis Test Glucose Urine Strips EUMED Biotechnology EUsure Blood Glucose Monitoring System EUkare Blood Glucose Monitoring System cHPV Detection System Fisher Healthcare Own Brand Diagnostic Products Agreements Financials FlexSite diagnostics HbA1c Test Microalbumin Test Genzyme Diagnostics Point of Care Tests Development Projects Helena Laboratories Point of Care Haemostasis Coagulation FOB Testing Hema Diagnostic Systems Home Access Health Corporation Home Diagnostic Tests Horiba ABX Medical Diagnostic Instruments and Systems - Major Products New Reagent Plant Agreements Financials IND Diagnostic Fertility Tests Infectious Disease Tests (Hepatitis B, Hepatitis C and HIV) Sexually Transmitted Disease Tests Tumour Marker Tests Cardiac Marker Tests Drugs-of-Abuse Tests Urinalysis Reagent Tests Urine Analyser Instrumentation Laboratory Blood Gas/CO-Oximetry/Electrolytes/Metabolites Haemostasis Coagulation CO-Oximetry Information Management Agreements Supply Agreement International Technidyne Corp Hospital POC Coagulation Hospital POC Blood Gas Alternate Site Diagnostics Haemoglobin Testing Agreements Financials Inverness Medical Innovations Professional Diagnostic Products Inverness Medical Professional Rapid Diagnostics - Product Revenue* 2002-2006 (US$ million) Point-of-Care Tests Consumer Diagnostics - Fertility/Pregnancy IMA Pregnancy/Fertility Product Revenue*, 2002-2006, US$ million. Acquisitions Equity Investments Joint Venture Agreements Research and Development Financials Inverness Medical Financial Results - YTD Fiscal 2007 Iris Diagnostics Urine Chemistry Analyser for Physician Offices Agreements Financials Jant Pharmacal Infectious Disease Tests Pregnancy and Fertility Cardiac Screening Products Drugs-of-Abuse Hypothyroidism Screening Rapid UTI Screen Sleep Apnoea Screen Lifestyle Choices Ltd Triple Hormone Ovarian Reserve Test Matritech Bladder Cancer Test Agreements Financials Comparison of Revenue, 2005-2006 Medical Automation Systems RALS-Plus Agreements Acquisitions MedMira Laboratories HIV and Hepatitis C Tests HIV Tests Hepatitis B Test Hepatitis C Test H. pylori Test Acquisitions Agreements Patents Financials Menarini Diagnostics Medtronic ACT Plus Automated Coagulation Timer System HMS PLUS Haemostasis Management System Financials MCM Corporation Cardiac Infarction Test Meridian Bioscience E.coli Test C.difficile Test H. pylori Test RSV Test Strep A Test Financials MYCROLAB MycroCARD Miniaturised Diagnostic Testing System Nanogen Test for CHF Tests for ACS and AMI Drugs-of-Abuse Test In Development Agreements Acquisitions. Financials Nanosphere Verigene System Focus Areas Agreements Nova Biomedical Blood Gas Critical Care Analysers Nova Electrolyte/Chemistry Analysers Data Management Supply Agreements Omega Pharma Home Pregnancy Test OraSure Technologies HIV Tests Drugs of Abuse Agreements Supply Agreements Research and Development Financials Orion Diagnostica Point-of-Care Tests Financials OrSense Haemoglobin Monitoring Ortho-Clinical Diagnostics Clinical Chemistry Analyser Financials OPTI Medical Blood Gas Analysis Point-Of-Care CO-Oximeter Financials Polymedco Point of Care/Rapid Diagnostics Polymer Technology Systems (PTS) CardioChek P.A System (Professional System) Prima Biomedical One Step Rapid Tests Quantitative Rapid Tests Urinalysis Blood Glucose Rapid Tests Instruments PreMD Inc PREVU Point of Care Skin Sterol Test Cancer Tests Agreements Financials Princeton BioMeditech Home Pregnancy Tests Infectious Disease Tests Drugs of Abuse Tests Tumour Marker Tests Cardiac Marker Tests Agreements Probe Scientific MicroEye Blood Analysis Device Agreements Proteome Systems DiagnostIQ Agreements Diagnostic test for Ovarian Cancer Quest Diagnostics HemoCue POC products Focus Diagnostics’ POC Products. Enterix’POC Products Acquisitions Agreements Quidel Corporation Products Research and Development Agreements Acquisitions Financials Radiometer Blood Gas Analysers Quality Control IT Systems QA Support Agreements Group Purchasing Organisation (GPO) Partners Financials Remel Xpect Rapid Diagnostic Tests Oxoid PBP2 Test Financials Response Biomedical Corp RAMP System Cardiac Markers Influenza Agreements Financials Roche Diagnostics Coagulation Monitoring Systems Cardiac Markers Hospital Blood Gas/Electrolytes Multi-parameter Clinical Chemistry Analysers Urinalysis Point of Care Data Management Financials Roche Point-of Care Diagnostics' Sales, 2004-2006 (SFr million) Roche Point-of Care Diagnostics' Sales*, 2004-2006 (US$ million) Roche Point-of Care Diagnostics' Sales*, 2004-2006 (US$ million) Roche Diagnostics Division, 2006 Results Rohto Pharmaceutical Pregnancy Test Kit Ovulation Test Kit Runbio Biotech Fertility Tests Infectious Diseases Tumour Marker Tests Sexually-Transmitted Disease Tests Drugs-of-abuse Tests SA Scientific Fertility Infectious Diseases Siemens Medical Solutions Diagnostics POC Product Line Dade Behring Products Acquisitions Agreements Supply Agreements Financials SIENCO Platelet Function Analyser Data Management Stanbio Laboratory POC Haematology Analysers Rapid Tests Infectious Diseases Agreements Syntron Bioresearch Blood Glucose Testing Drugs-of-abuse testing Cholesterol Tests Fertility Tests Sysmex Haematology Analysers Influenza Test Coagulation Analyser Agreements Financials Telcor Point Of Care Testing (POCT) Information System Tosoh Bioscience Benchtop Immunoassay Analysers AIA-600 II Trinity Biotech POC Infectious Disease Tests Comparison of POC HIV Tests POC Pregnancy Acquisitions Agreements Litigation Settlement Financials Via Medical VIA Blood Gas and Chemistry Monitor VIA LVM Neonatal System VIA Blood Glucose Monitoring System WayPoint Biomedical OTC Market Professional Point of Care Tests International Products Agreements References POC Market Overview Executive Summary IV D Market Figure 1: Global IVD Market by Geographic Region 2007 US$33.6 Billion. Figure 2: IVD Market Leaders Figure 3: EDMA 2006 IVD Market Estimates Figure 4: POCT Relative to the Global IVD Market, 2007 Figure 5: Global POCT Market by Geographic Region 2007 US$11.32 billion POC Market Sectors Figure 6: POC Market by Segment, excluding Blood Glucose Testing, 2007, Total US$3.87 billion POC Testing in the US POC Testing in Europe Figure 7: European Point of Care Market 2007 (US$3.44 billion) POC Growth Drivers Healthcare Trends Demographic Changes Advantages of POC Testing Social Pressure Industry Pressure Technology Advancements Challenges to POC Cost Issues Interfacing/Connectivity Issues Regulatory Compliance and Quality Control Central Laboratory Competition Summary - Future Advances in POC Emerging POC Technologies Nucleic Acid Lateral Flow (NALF) Fluorescence Reader Systems University of Illinois - DNA-Gold Nanoparticle Technology Probe Scientific Pharmacogenetic Testing AMDL Blood Glucose Market Table 1: WHO Diabetes Prevalence Estimates Table 2: Prevalence of Diabetes in Selected Countries in the WHO European Region Diabetes BGM Technologies Figure 8: Leading Manufacturers’ Diabetes Care Revenues* 2004-2006 (US$ million) Table 3: Leading Manufacturers’ Diabetes Care Revenues 2004-2006 (US$ million) Table 4: Leading Manufacturers’ Diabetes Care Revenues – First Nine Months of Fiscal 2007 (US$ million) BGM Market and Market Leaders. Continuous Glucose Monitoring Systems Medtronic DexCom Abbott Diabetes Care Menarini Diagnostics PreciSense Summarised One Day Pilot – Clinical Results Summarised Pre-clinical Results (2006) Funding Long-Term Glucose Biosensors Sensors for Medicine & Science (SMSI) DexCom Animas Non-Invasive BGM technologies OrSense AiMedics Calisto Medical GlucoLight Corporation Glucon GluMetrics Integrity Applications Kumetrix Lein Applied Diagnostics LighTouch Medical Luminous Medical iSense NIR Diagnostics NIBGM Oculir Pindi Products Sensors for Medicine & Science Echo Therapeutics (formerly Sontra Medical). SpectRx Synthetic Blood International (SYBD) VeraLight Freedom Meditech Sensys Medical Solianis Monitoring Current Blood Glucose Monitoring Systems Roche Diabetes Care Roche Diabetes Care Sales – First Nine Months of Fiscal 2007 (SFr million) Roche Diabetes Care Sales 2005-2006 (SFr million) LifeScan (J&J) Abbott Diabetes Care Abbott Diabetes Care – Product Sales, First Nine Months of Fiscal 2007 Abbott Diabetes Care – Product Sales, 2004-2006 Bayer Diabetes Care Ascensia Sales – First Nine Months of Fiscal 2007 (EUR Million) Arkray Menarini Diagnostics Home Glucose Testing Home Diagnostics, Inc Medtronic Diabetes 77 Electronica Kft Blood Glucose Meters LiteLink Wireless Data Download Device AgaMatrix WaveSense Jazz Apex Biotechnology Diabetech EUMED Biotechnology Glucoplus HMD Bio Medical HemoCue AB Nova Biomedical TaiDoc Technology Corporation US Diagnostics HbA1c Testing Professional HbA1C Systems Self-Testing HbA1c Systems POC Cardiology Diagnos tics POC Coagulation Testing PT/INR Testing in the US PT/INR Testing in Europe Table 5: Reimbursement for PT/INR Testing in Europe PT/INR POC Market Leaders PT/INR Analysers POC Cardiac Marker Market Most Frequently Used Cardiac Markers Cardiac Marker - Market Leaders C-reactive protein (CRP) POC Blood Gas/Electrolytes Market Radiometer Siemens Medical Solutions Diagnostics Roche Diagnostics Nova Biomedical Instrumentation Laboratory International Technidyne Corporation Abbott Diagnostics OPTI Medical (formerly Osmetech) Blood Gas and Chemistry Monitors POC Clinical Chemistry/Urinalysis Blood Chemistry Analysers Urinalysis Iris International Arkray Hypoguard (Arkray) POC Cholesterol Testing Table 5: Initial classification based on total cholesterol and HDL cholesterol POC Haematology POC Haematology Analysers POC Haemoglobin Analysers POC Platelet Function Analaysers POC Infectious Disease Test Market. HAI s HIV Table 6: Regional HIV/AIDS Statistics Table 7: National Hospital Ambulatory Medical Survey 2002 Emergency Department Summary (USA) Table 8: Comparison of POC HIV Tests Currently Available HIV Tests for the POC Market Tuberculosis Hepatitis B Hepatitis B Tests Hepatitis C Influenza Table 9: Flu A & B Tests - Performance Comparison: Sensitivity and Specificity Respiratory Syncytial Virus Table 10: RSV Performance Comparison: Sensitivity and Specificity S. aureus and MRSA Streptococcal Infectious Disease tests Strep B Tests C.difficile Tests Other Infectious Disease Tests H. pylori Mononucleosis Tests Malaria Tests POC Drugs-of-Abuse Testing Inverness Medical Princeton BioMeditech Dade Behring (Siemens) Alfa Scientific Bio-Rad Branan Medical IND Diagnostics Instant Technologies WayPoint Biomedical POC Tumou r Marker Tests FOB Testing PSA and Other Tumour Marker Tests POC Pregn ancy /Fertility Market Figure 9: Global Pregnancy and Fertility Market Inverness Medical Pregnancy/Fertility Product Revenues Home Pregnancy Tests Professional Pregnancy Tests Fertility Tests POINT-OF-CARE DATA MANAGEMENT Medical Automation Systems Abbott Diagnostics Instrumentation LaboratoryMenarini Diagnostics References Table of Contents

Companies Mentioned

- Abaxis - Piccolo - bioMérieux SA - PSS World Medical - Chatani - Abbott Diagnostics - i-STAT - Axis-Shield - OraSure - Accumetrics - ACON Laboratories - MedSurge Medical - SpotChem EZ - Eli Lilly - Roche Diagnostics - Branan Medical - Church & Dwight - Quidel - Vitalab Fibron - Dade Behring - ZyCare - ABX Pentra - Bayer Diagnostics - Iris International - ITI Scotland Limited - Lifestream Technologies - Omega Pharma