Cholesterol & Other Cardiovascular Testing - Global Strategic Business Report - Market Research Reports

Contents:

CHOLESTEROL AND OTHER CARDIOVASCULAR TESTING
A GLOBAL STRATEGIC BUSINESS REPORT

CONTENTS

1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS 1
Study Reliability and Reporting Limitations 1
Disclaimers 2
Data Interpretation & Reporting Level 3
Quantitative Techniques & Analytics 3
Product Definitions and Scope of Study 3
Lipid Panel Test/Complete Lipid Profile 3
Total Cholesterol Test 4
HDL Cholesterol Test 4
Apolipoprotein B 4
Other Apolipoprotein Tests 4

2. INDUSTRY OVERVIEW 5
Global Market Outlook 5
Tests Conducted Worldwide 5
Analysis by Geographic Region 5
Analysis by Product Segment 6
Home/OTC Cholesterol Test Kits Market: A Review 6
Growth Drivers 6
Aging Population Drives Home Testing Market 6
Extensive Awareness Campaigns for Common People 6
Global In-Vitro Diagnostic Products Market: An Overview 7
Growth Trends 8
Table 1: Global In-Vitro Diagnostics Products Market (2007):
Percentage Breakdown of Value Sales for North America,
Europe, Japan and Rest of World (includes corresponding
Graph/Chart) 8
Established Players Dominate the Fragmented Market 8
Table 2: Leading Players in the Global In-Vitro Diagnostics
Market (2009): Percentage Breakdown of Value Sales for Roche
Diagnostics, Abbott Diagnostics, Ortho/ LifeScan,
Bayer/Siemens, Beckman Coulter, BD, Dade Behring, bioMerieux
and Others (includes corresponding Graph/Chart) 9
Cardiac IVD Market to Grow 9

3. AN INSIGHT INTO CARDIOVASCULAR DISEASES 10
The Heart of Heart Problems 10
Types of Cardiovascular Diseases/Disorders 10
Coronary Artery Disease 10
Hyperlipidemia - An Important Risk Factor of Heart Disease 10
Hypertension - The Silent Killer 11
Two-Pronged Approach to Counter CVD 12
Cardiovascular Risk Assessment 12
Reality Check 12

4. GOOD & BAD OF CHOLESTEROL 14
Blood Cholesterol - The Principal Cardiac Risk Marker 14
Types of Cholesterol 14
Total Cholesterol (TC) 14
High Density Lipoprotein (HDL) 15
Low Density Lipoprotein (LDL) / Very Low Density Lipoprotein
(VLDL) 15
Triglycerides (TRG) 15
Glucose (GLU) 15
Alanine Aminotransferase (ALT) 15
Outcomes of High Blood Cholesterol 15
Atherosclerosis 15
Coronary Heart Disease (CHD) 15
Risk Factors and Risk Levels 16
Risk Factors 16
Risk Levels 16
Risk Level Based on Total Cholesterol Concentration 16
LDL-Cholesterol Risk Levels 16
HDL-Cholesterol Risk Levels 17
Triglyceride Risk Levels 17

5. CHOLESTEROL TESTING & CVD RISK ASSESSMENT TECHNIQUES 18
Cholesterol Testing 18
Need for Cholesterol Testing 18
Candidates for Cholesterol Testing 18
Test Procedure 19
Time of Testing - Crucial for Heart Disease Patients 19
Types of Cholesterol Testing 20
Lipid Panel Test/Lipid Profile 20
Total Cholesterol Test 21
HDL Cholesterol Test 21
Apolipoprotein Tests 21
Apolipoprotein A-1 Test 21
Apolipoprotein B100 Test 22
ApoE Genotyping Test 22
Apolipoprotein CII 22
Other Cholesterol Markers 22
LDL Cholesterol Testing 22
LDL Cholesterol Test - The First Cholesterol Testing Method 22
Triglycerides/VLDL Cholesterol Testing 23
RLP Cholesterol 23
Non Instrumented Technologies 23
Heart Disease Diagnosis Tests 23
Non-Invasive Tests 24
Invasive Tests 24
Other CVD Markers 24
Creatine Kinase MB 25
Troponin T and Troponin I 25
Myoglobin 25
P-selectin Profile 25
C-reactive Protein 26
Endothelial Dysfunction 26
Homocysteine 26
Plasminogen Activator Inhibitor-1 27
s-100 Protein 27
Thrombus Precursor Protein 28
Other Cardiac Markers 28

6. POINT OF CARE & HOME CHOLESTEROL TESTING 29
Point of Care (POC) Medical Diagnostics 29
Table 3: Global Point of Care Diagnostics Market (2008):
Percentage Breakdown of Value Sales by Segment - Hospital
Labs, Commercial Labs, Self Testing and Point of Care
(includes corresponding Graph/Chart) 29
POC Testing Market 29
Table 4: Global Cholesterol Point-of-Care Rapid Tests Market
(2009): Market Shares of Leading Players by Value Sales for
Inverness Medical, Roche, Abaxis, and Others (includes
corresponding Graph/Chart) 30
Development of Home Cholesterol Testing Kits 30
Cholesterol and Other Cardiovascular Test Kits Offered by
Leading Companies 30

7. CHOLESTEROL CONTROL & TREATMENT MODALITIES 31
Prevention is Better than Cure 31
Dietary Therapy 31
Healthy Diet 31
Exercises 32
Drug Therapy 32
Classification of Cholesterol Lowering Drugs 32
Bile Acid Sequestrants 32
Nicotinic Acid 33
HMG CoA Reductase Inhibitors (Statins) 33
Other Drugs (Fibric Acids and Probucol) 33
Testing After Commencing Drug Therapy 33

8. PRODUCT INTRODUCTIONS/INNOVATIONS 35
SpectraCell Laboratories Launches Lp-PLA2 Test 35
Polymer Technology Launches Cardio Diagnostic Analyzer 35
Digital Division Introduces Cholesterol Screening Locator 35
Interleukin Genetics Unveils Improved Test Report Format for
Heart Health Genetic Test 35
Axis-Shield to Develop Lipid Panel Test for Afinion™ Point-of
-Care System 36
Home Access Health Launches CheckUp America Cholesterol Panel 36

9. PRODUCT INNOVATIONS/LAUNCHES IN RECENT PAST- A PERSPECTIVE BUILDER 37
Cholestech Launches Lipid Profile*ALT Test Cassette 37
Home Access Health Develops an Algorithm for Home Test 37
Cholestech Unveils Innovative Dermatology Kit 37
Beckman Coulter Unveils UniCel® DxI 600 Access® Immunoassay
System 38
Polymer Technology Systems Launches Direct LDL Cholesterol Test 38
Dade Behring Unveils CardioPhase® hsCRP Test 39
PTS Introduces First Ever Direct LDL Cholesterol Test 39

10. RECENT INDUSTRY ACTIVITY 40
Miraculins Acquires PreMD’s PREVU(i) Skin Cholesterol Test Assets 40
Kardia Health Systems Partners with TomTec Imaging Systems 40
BioMérieux Takes Over Meikang Biotech 40
Inverness Medical Innovations Adopts New Name 40
Aurora Health Care Partners with Celera 41
iZumi Bio Merges Business with Pierian to Create iPierian 41
Medical Technologies Collaborates with NASA for Cardiovascular
Testing 41
Berkeley HeartLabs Inks Agreements with Geisinger Medical
Center and Proven Diagnostics 42
ARCA biopharma and Nuvelo Complete Merger 42
Thermo Fisher Scientific Acquires B.R.A.H.M.S. 42
Mediscience Technology Corporation Acquires SensiVida Medical
Systems 42
Medrad Merges Operations with Possis Medical 42
Roche Inks Agreement with Response Biomedical 43
Dynatek Dalta Scientific Instruments Inks Agreement with State
Food and Drug Administration 43
Abbott’s TRILIPIX Receives Approval from FDA 43
Signalife Establishes Signalcare 43
Amic Inks Licensing Deal with Roche Diagnostics 44
GE Healthcare Collaborates with Boston Scientific 44
TRICARE Includes Atherotech’s VAP® Test 44
PreMD Receives NSE Letter from US FDA for POC Skin Cholesterol
Test 45
Amic Gains License for Roche’s Cardiac Marker 45
Acrongenomics and Molecular Vision Enter into Joint
Collaboration Agreement 45
diaDexus and Fisher HealthCare Sign Agreement 45

11. CORPORATE ACTIVITY IN RECENT PAST - A PERSPECTIVE BUILDER 47
Beckman Coulter Partners for Cardiovascular Research Project 47
Siemens Acquires Bayer’s Diagnostic Division 47
Response Biomedical Gains Approval to Sell RAMII® NT- proBNP Test 47
Endothelix Obtains FDA Approval for VENDYS® Cardiovascular Test 48
Cholestech Receives CLIA Waived Status for Lipid Profile ALT
Test Panel 48
Kellogg Partners with Omron Healthcare and BIOSAFE® 48
Siemens Acquires Dade Behring 49
Inverness Medical Innovations Concludes Cholestech Acquisition 49
QuantRX Biomedical Increases Stake in FluoroPharma 49
Celera Takes Over Berkeley HeartLab 50
Inverness Medical Innovations Completes Acquisition of HemoSense 50
LipoScience and BioReference Announce Collaboration 50
PreMD and AstraZeneca Sign Distribution Agreement 51
Atherotech Reaches an Agreement with Source Scientific 51
Siemens Acquires Diagnostic Products Corporation 51
Nanogen Acquires Spectral’s Cardiac Test Division 52
Instant Technologies Takes Over Accu-Stat Diagnostics 52
Source Scientific and Atherotech Collaborate for VAP Test Devices 52
Abbott Receives Non-exclusive Sublicense for Diagnostic Use of
PIGF 53
Cholestech to Supply LDX® System to Mexican Ministry of
Communications & Tranportation 53

12. FOCUS ON SELECT PLAYERS 54
AccuTech, LLC (US) 54
Alere, Inc.(US) 54
Biosite, Inc. (US) 55
Cholestech Corporation (US) 55
Axis-Shield Plc (UK) 56
Beckman Coulter, Inc. (US) 56
F. Hoffmann-La Roche Ltd (Switzerland) 56
Home Access Health Corporation (US) 57
Polymer Technology Systems, Inc. (US) 57
Siemens Healthcare Diagnostics, Inc. (US) 58

13. GLOBAL MARKET PERSPECTIVE 59
Table 5: World Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Geographic
Region - US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America and Rest of World Independently Analyzed
with Annual Sales Figures in Million Units for Years 2007
through 2015 (includes corresponding Graph/Chart) 59

Table 6: World Historic Review for Cholesterol & Other
Cardiovascular Testing by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Latin America,
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 60

Table 7: World 11-Year Perspective for Cholesterol & Other
Cardiovascular Testing by Geographic Region - Percentage
Breakdown of Unit Sales for US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Latin America and Rest of
World Markets for Years 2005, 2010 & 2015 (includes
corresponding Graph/Chart) 61

Table 8: World Recent Past, Current & Future Analysis for
Lipid Panel Test/Complete Lipid Profile Testing by Geographic
Region -United States, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America, and Rest of World
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2007 through 2015 (includes corresponding
Graph/Chart) 62

Table 9: World Historic Review for Lipid Panel Test/Complete
Lipid Profile Testing by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Latin America
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 63

Table 10: World 11-Year Perspective for Lipid Panel Test/
Complete Lipid Profile Testing by Geographic Region -
Percentage Breakdown of Unit Sales for US, Canada, Japan,
Europe, Asia-Pacific (excluding Japan), Latin America, and
Rest of World Markets for Years 2005, 2010 & 2015 (includes
corresponding Graph/Chart) 64

Table 11: World Recent Past, Current & Future Analysis for
Total Cholesterol Testing by Geographic Region - United
States, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America, and Rest of World Independently Analyzed with
Annual Sales Figures in Million Units for Years 2007 through
2015 (includes corresponding Graph/Chart) 65

Table 12: World Historic Review for Total Cholesterol Testing
by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2000 through 2006 (includes corresponding
Graph/Chart) 66

Table 13: World 11-Year Perspective for Total Cholesterol
Testing by Geographic Region - Percentage Breakdown of Unit
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Markets for Years
2005, 2010 & 2015 (includes corresponding Graph/Chart) 67

Table 14: World Recent Past, Current & Future Analysis for HDL
Cholesterol Testing by Geographic Region - United States,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America, and Rest of World Independently Analyzed with Annual
Sales Figures in Million Units for Years 2007 through 2015
(includes corresponding Graph/Chart) 68

Table 15: World Historic Review for HDL Cholesterol Testing by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2000 through 2006 (includes corresponding
Graph/Chart) 69

Table 16: World 11-Year Perspective for HDL Cholesterol
Testing by Geographic Region - Percentage Breakdown of Unit
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Markets for Years
2005, 2010 & 2015 (includes corresponding Graph/Chart) 70

Table 17: World Recent Past, Current & Future Analysis for
Apolipoprotein B Tests by Geographic Region - United States,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America, and Rest of World Independently Analyzed with Annual
Sales Figures in Million Units for Years 2007 through 2015
(includes corresponding Graph/Chart) 71

Table 18: World Historic Review for Apolipoprotein B Tests by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2000 through 2006 (includes corresponding
Graph/Chart) 72

Table 19: World 11-Year Perspective for Apolipoprotein B Tests
by Geographic Region - Percentage Breakdown of Unit Sales for
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America, and Rest of World Markets for Years 2005, 2010 &
2015 (includes corresponding Graph/Chart) 73

Table 20: World Recent Past, Current & Future Analysis for
Other Apolipoprotein Tests by Geographic Region - United
States, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America, and Rest of World Independently Analyzed with
Annual Sales Figures in Million Units for Years 2007 through
2015 (includes corresponding Graph/Chart) 74

Table 21: World Historic Review for Other Apolipoprotein Tests
by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2000 through 2006 (includes corresponding
Graph/Chart) 75

Table 22: World 11-Year Perspective for Other Apolipoprotein
Tests by Geographic Region - Percentage Breakdown of Unit
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Markets for Years
2005, 2010 & 2015 (includes corresponding Graph/Chart) 76

14. THE UNITED STATES 77
A.Market Analysis 77
Market Outlook 77
In-Vitro Diagnostic Products Market: A Snapshot 77
Cardiovascular Market: Startling Statistics 77
Table 23: Prevalence of Cardiovascular Disease (CVD) in the
US: Population by Disease Type (in 000s) (includes
corresponding Graph/Chart) 78
Cholesterol Testing - NCEP Recommendations Spurs Potential 78
Trends and Issues 79
Innovations Drive the Usage of Cardiovascular Monitoring
Systems 79
Sterols and Stanols: Cholesterol-Lowering Products 79
Cholesterol POCT Market: An Overview 79
Table 24: US Cholesterol Point-of-Care Testing (2009):
Market Shares of Leading Players by Value Sales for
Inverness Medical, Polymer Technology Systems, and Roche
Diagnostics (includes corresponding Graph/Chart) 80
Increasing Cardiovascular Ailments Drive Sales of Home Test
Devices 80
Table 25: US Recent Past, Current & Future Analysis for
Home Cholesterol Monitoring Kits Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2007
through 2015 (includes corresponding Graph/Chart) 80

Table 26: US Historic Review for Home Cholesterol
Monitoring Kits Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2000 through 2000
(includes corresponding Graph/Chart) 81
B.Market Analytics 81
Table 27: US Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment - Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 81

Table 28: US Historic Review for Cholesterol & Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 82

Table 29: US 11-Year Perspective for Cholesterol & Other
Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 83

15. CANADA 84
Market Analysis 84
Table 30: Canadian Recent Past, Current & Future Analysis
for Cholesterol & Other Cardiovascular Testing by Product
Segment - Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 84

Table 31: Canadian Historic Review for Cholesterol & Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 85

Table 32: Canadian 11-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 86

16. JAPAN 87
Market Analysis 87
Table 33: Japanese Recent Past, Current & Future Analysis
for Cholesterol & Other Cardiovascular Testing by Product
Segment - Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 87

Table 34: Japanese Historic Review for Cholesterol & Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 88

Table 35: Japanese 11-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 89

17. EUROPE 90
A.Market Analysis 90
Market Outlook 90
Home Cholesterol Monitoring Kits Market in Western Europe 91
Table 36: Western Europe Recent Past, Current & Future
Analysis for Home Cholesterol Monitoring Kits Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2007 through 2015 (includes corresponding Graph/Chart) 91

Table 37: Western Europe Historic Review for Home
Cholesterol Monitoring Kits Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2006 (includes corresponding Graph/Chart) 91
B.Market Analytics 92
Table 38: European Recent Past, Current & Future Analysis
for Cholesterol & Other Cardiovascular Testing by Geographic
Region - France, Germany, Italy, UK, Spain, Russia and Rest
of Europe Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2007 through 2015
(includes corresponding Graph/Chart) 92

Table 39: European Historic Review for Cholesterol & Other
Cardiovascular Testing by Geographic Region - France,
Germany, Italy, UK, Spain, Russia and Rest of Europe Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2000 through 2006 (includes corresponding
Graph/Chart) 93

Table 40: European 11-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Geographic Region -
Percentage Breakdown of Unit Sales for France, Germany,
Italy, UK, Spain, Russia and Rest of Europe Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 94

Table 41: European Recent Past, Current & Future Analysis
for Cholesterol & Other Cardiovascular Testing by Product
Segment - Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 95

Table 42: European Historic Review for Cholesterol & Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 96

Table 43: European 11-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 97

17a. FRANCE 98
Market Analysis 98
Table 44: French Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment - Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 98

Table 45: French Historic Review for Cholesterol & Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 99

Table 46: French 11-Year Perspective for Cholesterol & Other
Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 100

17b. GERMANY 101
Market Analysis 101
Table 47: German Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 101

Table 48: German Historic Review for Cholesterol & Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 102

Table 49: German 11-Year Perspective for Cholesterol & Other
Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 103

17c. ITALY 104
Market Analysis 104
Table 50: Italian Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 104

Table 51: Italian Historic Review for Cholesterol & Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 105

Table 52: Italian 11-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 106

17d. UNITED KINGDOM 107
Market Analysis 107
Table 53: UK Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 107

Table 54: UK Historic Review for Cholesterol & Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 108

Table 55: UK 11-Year Perspective for Cholesterol & Other
Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 109

17e. SPAIN 110
Market Analysis 110
Table 56: Spanish Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 110

Table 57: Spanish Historic Review for Cholesterol & Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2006
(includes corresponding Graph/Chart) 111

Table 58: Spanish 11-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 112

17f. REST OF EUROPE 113
Market Analysis 113
Table 59: Rest of Europe Recent Past, Current & Future
Analysis for Cholesterol & Other Cardiovascular Testing by
Product Segment - Lipid Panel Test/Complete Lipid Profile,
Total Cholesterol Test, HDL Cholesterol Test, Apolipoprotein
B, and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 113

Table 60: Rest of Europe Historic Review for Cholesterol &
Other Cardiovascular Testing by Product Segment - Lipid
Panel Test/Complete Lipid Profile, Total Cholesterol Test,
HDL Cholesterol Test, Apolipoprotein B, and Other
Apolipoprotein Tests Markets Independently Analyzed with
Annual Sales Figures in Million Units for Years 2000 through
2006 (includes corresponding Graph/Chart) 114

Table 61: Rest of Europe 11-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment -
Percentage Breakdown of Unit Sales for Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets for Years 2005, 2010 & 2015 (includes
corresponding Graph/Chart) 115

18. ASIA-PACIFIC 116
Market Analysis 116
Table 62: Asia-Pacific Recent Past, Current & Future
Analysis for Cholesterol & Other Cardiovascular Testing by
Product Segment - Lipid Panel Test/Complete Lipid Profile,
Total Cholesterol Test, HDL Cholesterol Test, Apolipoprotein
B, and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 116

Table 63: Asia-Pacific Historic Review for Cholesterol &
Other Cardiovascular Testing by Product Segment - Lipid
Panel Test/Complete Lipid Profile, Total Cholesterol Test,
HDL Cholesterol Test, Apolipoprotein B, and Other
Apolipoprotein Tests Markets Independently Analyzed with
Annual Sales Figures in Million Units for Years 2000 through
2006 (includes corresponding Graph/Chart) 117

Table 64: Asia-Pacific 11-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 118

19. LATIN AMERICA 119
Market Analysis 119
Table 65: Latin America Recent Past, Current & Future
Analysis for Cholesterol & Other Cardiovascular Testing by
Product Segment - Lipid Panel Test/ Complete Lipid Profile,
Total Cholesterol Test, HDL Cholesterol Test, Apolipoprotein
B, and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 119

Table 66: Latin America Historic Review for Cholesterol &
Other Cardiovascular Testing by Product Segment - Lipid
Panel Test/Complete Lipid Profile, Total Cholesterol Test,
HDL Cholesterol Test, Apolipoprotein B, and Other
Apolipoprotein Tests Markets Independently Analyzed with
Annual Sales Figures in Million Units for Years 2000 through
2006 (includes corresponding Graph/Chart) 120

Table 67: Latin America 11-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment -
Percentage Breakdown of Unit Sales for Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets for Years 2005, 2010 & 2015 (includes
corresponding Graph/Chart) 121

20. REST OF WORLD 122
Market Analysis 122
Table 68: Rest of World Recent Past, Current & Future
Analysis for Cholesterol & Other Cardiovascular Testing by
Product Segment - Lipid Panel Test/Complete Lipid Profile,
Total Cholesterol Test, HDL Cholesterol Test, Apolipoprotein
B, and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2007 through 2015 (includes corresponding Graph/Chart) 122

Table 69: Rest of World Historic Review for Cholesterol &
Other Cardiovascular Testing by Product Segment - Lipid
Panel Test/Complete Lipid Profile, Total Cholesterol Test,
HDL Cholesterol Test, Apolipoprotein B, and Other
Apolipoprotein Tests Markets Independently Analyzed with
Annual Sales Figures in Million Units for Years 2000 through
2006 (includes corresponding Graph/Chart) 123

Table 70: Rest of World 11-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment -
Percentage Breakdown of Unit Sales for Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets for Years 2005, 2010 & 2015 (include
corresponding Graph/Chart) 124

COMPETITIVE LANDSCAPE

Total Companies Profiled: 42 (including Divisions/Subsidiaries - 52)

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Region/Country Players
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The United States 35
Canada 1
Japan 4
Europe 9
Germany 1
The United Kingdom 4
Italy 1
Rest of Europe 3
Asia-Pacific (Excluding Japan) 3
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