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Cholesterol and Other Cardiovascular Testing - Global Strategic Business Report


Description: This report analyzes the worldwide markets for Cholesterol & Other Cardiovascular Testing in Millions of Units. The specific product segments analyzed are Lipid Panel Test/Complete Lipid Profile, Total Cholesterol Test, HDL Cholesterol Test, and Apolipoprotein B. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World. Annual forecasts are provided for each region and product segment for the period of 2000 through 2010. The report profiles 43 companies including many key and niche players worldwide such as AccuTech, LLC, Axis-Shield PLC, Biosite Inc., Cholestech Corporation, Dade Behring, Home Access Health, Lifestream Technologies, Inc., and Roche Diagnostics. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

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Contents: CHOLESTEROL AND OTHER CARDIOVASCULAR TESTING
A GLOBAL STRATEGIC BUSINESS REPORT


CONTENTS



I.INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability And Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-2
Quantitative Techniques & Analytics I-2
Product Definitions And Scope Of Study I-3
Lipid Panel Test/Complete Lipid Profile I-3
Total Cholesterol Test I-3
HDL Cholesterol Test I-3
Apolipoprotein B I-3
Other Apolipoprotein Tests I-3

II.
1. Industry Overview II-1
Global Market Outlook II-1
Cholesterol Testing to Witness No-Holds Barred Growth II-1
Tests Conducted Worldwide II-1
Analysis by Geographic Region II-1
Analysis by Product Segment II-2
Home/OTC Cholesterol Test Kits Market Set for Double-Digit
Growth II-2
Growth Drivers II-2
Aging Population Drives Home Testing Market II-2
Extensive Awareness Campaigns for Common People II-3
Global In-Vitro Diagnostic Products Market: An Overview II-3
Growth Trends II-4
Table 1: World In-Vitro Diagnostic (IVD) Testing Market
(2004): Percentage Breakdown by Value Sales for United
States, Europe, Japan, Asia-Pacific, and Rest of World
(includes corresponding Graph/Chart) II-5
Established Players Dominate a Fragmented Industry II-5
Table 2: Leading Players in the Worldwide In-
VitroDiagnostics Market (2004): Percentage Breakdown by
Value Sales for Roche, Abbott, J & J/Ortho, Bayer, Beckman
Coulter, Dade Behring, and Others (includes corresponding
Graph/Chart) II-5
Worldwide Home IVD Products Market
An Overview II-6

2. An Insight into Cardiovascular Diseases II-7
The Heart of Heart Problems II-7
Types of Cardiovascular Diseases/Disorders II-7
Coronary Artery Disease II-7
Hyperlipidemia
An Important Risk Factor of Heart Disease II-7
Hypertension
The Silent Killer II-8
Two-Pronged Approach to Counter CVD II-9
Cardiovascular Risk Assessment II-9

3. The Good & Bad of Cholesterol II-10
Blood Cholesterol
The Principal Cardiac Risk Marker II-10
Types of Cholesterol II-10
Total Cholesterol (TC) II-10
High Density Lipoprotein (HDL) II-10
Low Density Lipoprotein (LDL) / Very Low Density Lipoprotein
(VLDL) II-11
Triglycerides (TRG) II-11
Glucose (GLU) II-11
Alanine Aminotransferase (ALT) II-11
Outcomes of High Blood Cholesterol II-11
Atherosclerosis II-11
Coronary Heart Disease (CHD) II-11
Risk Factors and Risk Levels II-11
Risk Factors II-11
Risk Levels II-12
Risk Level Based on Total Cholesterol Concentration II-12
LDL-Cholesterol Risk Levels II-12
HDL-Cholesterol Risk Levels II-12
Triglyceride Risk Levels II-12

4. Cholesterol Testing & CVD Risk Assessment Techniques II-13
Cholesterol Testing II-13
Need for Cholesterol Testing II-13
Candidates for Cholesterol Testing II-13
Test Procedure II-14
Time of Testing
Crucial for Heart Disease Patients II-14
Types of Cholesterol Testing II-15
Lipid Panel Test/Lipid Profile II-15
Total Cholesterol Test II-15
HDL Cholesterol Test II-16
Apolipoprotein Tests II-16
Apolipoprotein A-1 Test II-16
Apolipoprotein B100 Test II-16
ApoE Genotyping Test II-17
Apolipoprotein CII II-17
Table 3: Prices of Cholesterol Tests by Type II-17
Other Cholesterol Markers II-17
LDL Cholesterol Testing II-17
LDL Cholesterol Test
The First Cholesterol Testing Method II-17
Triglycerides/VLDL Cholesterol Testing II-18
RLP Cholesterol II-18
Non Instrumented Technologies II-18
Heart Disease Diagnosis Tests II-18
Non-Invasive Tests II-18
Invasive Tests II-19
Other CVD Markers II-19
Creatine Kinase MB II-19
Troponin T and Troponin I II-20
Myoglobin II-20
P-selectin Profile II-20
C-reactive Protein II-21
Endothelial Dysfunction II-21
Homocysteine II-21
Plasminogen Activator Inhibitor-1 II-22
s-100 Protein II-22
Thrombus Precursor Protein II-22
Other Cardiac Markers II-23

5. Point-of-Care & Home Cholesterol Testing
A Budding Market II-24
Point of Care (POC) Medical Diagnostics II-24
Table 4: World Home Point-of-Care (POC) Testing
ProductsMarket (2004): Percentage Breakdown of Value Sales by
Region
United States, Europe, Japan, and Rest of World
(includes corresponding Graph/Chart) II-24
POC Cardiac Testing II-24
Table 5: Leading Players in the Worldwide POC Cardiac
Testing Market (2004): Percentage Breakdown of Value Sales
for Biosite, Dade Behring, Spectral Diagnostics, Roche, and
Others (includes corresponding Graph/Chart) II-25
Development of Home Cholesterol Testing Kits II-25
Table 6: Cholesterol and Other Cardiovascular Test Kits
Offered by Leading Companies II-25

6. Cholesterol Control & Treatment Modalities II-26
Prevention is Better than Cure II-26
Dietary Therapy II-26
Healthy Diet II-26
Exercises II-27
Drug Therapy II-27
Classification of Cholesterol Lowering Drugs II-27
Bile Acid Sequestrants II-27
Nicotinic Acid II-27
HMG CoA Reductase Inhibitors (Statins) II-28
Other Drugs (Fibric Acids and Probucol) II-28
New and Effective Drugs Being Developed II-28
Side Effects of Cholesterol Lowering Drugs II-29
Gemfibrozil II-29
HMG-CoA Reductase Inhibitors II-29
All cholesterol reducing drugs II-30
Testing After Commencing Drug Therapy II-30

7. An Overview of the Cardiovascular Drugs Market II-31
A Glance at Cardiovascular Drugs Market II-31
Leading Players II-32
Table 7: Leading Players in the Worldwide Cardiovascular
Drugs Market (2003 & 2004)
Percentage Breakdown of Value
Sales for Pfizer, Merck, Bristol-Myers Squibb, Novartis,
AstraZeneca/Takeda, and Others (includes corresponding
Graph/Chart) II-32
Cholesterol-Lowering Drugs Market II-32
Leading Players II-33
Table 8: Leading Brands in the Worldwide Cholesterol
Reducing Drugs Market (2004): Percentage Breakdown of
Value Sales for Lipitor (Pfizer Inc.), Zocor (Merck Inc.),
Pravachol (Bristol-MyersSquibb Co.) and Others (includes
corresponding Graph/Chart) II-33

8. Product Launches/Developments II-34
Dade Behring Unveils CardioPhase(R) hsCRP Test II-34
PTS to Distribute First Ever Direct LDL Cholesterol Test II-34
Liposcience Reinstates Blood Cholesterol Test II-34
Akers Launches TrII-Cholesterol Test II-34
Dade Behring Unveils Homocysteine Test on BN(TM) Systems II-34
Axis-Shield Introduces BNP Assay for IMx® system of Abbott II-35
Roche Unveils Cardiac pro-BNP Test II-35
Accutech Introduces a new Diagnostic Test called CholesTrak
for Women II-35
Martek Devises a new Technique to Discrete DHA Residue From
Triglycerides II-35
Quantimetrix Unveils a new Diagnostic Test for Determining
the Cholesterol Levels II-36
AccuTech Launches Cholesterol Reduction System Kit II-36
Cholestech Introduces ALT II-36
Matsushita Develops Compact Cholesterol Sensor II-36

9. Recent Industry Activity II-37
Nanogen Acquires Spectral’s Cardiac Test Division II-37
Instant Technologies Takes Over Accu-Stat Diagnostics II-37
Source Scientific and Atherotech Collaborate for VAP Test
Devices II-37
Abbott Receives Non-exclusive Sublicense for Diagnostic Use
of PIGF II-37
Cholestech to Supply LDX® System to Mexican Ministry of
Communications & Tranportation II-37
PTS Enters into a Distribution Agreement with Medical Home
Products II-38
Olympus’ AU3000i to Expand Market for Bayer’s BNP Assay II-38
PTS to Provide Test Strips to Lifestream Technologies for New
Cholesterol/HDL Test II-38
Skylight Biotech to Start Cholesterol Testing Center for Animals II-38
FDA Grants CLIA Waiver for Biosite’s Triage(R) BNP Test II-38
Response Biomedical Wins Nonexclusive License Rights for NT
-proBNP and Troponin T II-39
Medicure Gains Licensing Rights of Cholesterol- Lowering
Technology II-39
Atherotech Collaborates with Resverlogix Corp II-39
IMI Enters into an Agreement with McNeil II-39
Nymox Pharmaceutical Receives Patent for Saliva Cholesterol Test II-39
LabCorp Ties Up with Atherotech to Offer VAP Cholesterol Test II-39
ABAXIS Bags FDA Approval for Three Assays II-40
Cholestech Obtains Approval to Market its Cholestech GDX™
System in Canada II-40
Cholestech Sells WellCheck Subsidiary to ImpactHealth II-40
IMI and McNeil Inks Agreement II-41
Quaker Oats Joins Hands with Biosafe to Promote Cholesterol
Testing II-41
Agreement Between Cholestech and Bayer II-41
Cholestech Concludes Two Agreements with Sankyo Pharma II-41
Johnson & Johnson Acquires Heartport II-41
Distribution Agreement Between Cholestech and Moore Medical II-42
Cholestech Signs US$1 Million Contract with GMR II-42
Atherotech Strikes a Deal with Healthsouth II-42
Incyte Genomics Forms Alliance with 2 Netherlands Institutes II-42
European Patent for Cholestech II-42
RiceX Awards Rights to NutraStar II-43
BioMec Forms New Subsidiary II-43
Cholestech Buys Health Net II-43
Lifestream Obtains Marketing Approval for its Home Cholesterol
Testing Device II-43
Polymer Receives FDA Approval to Market its HDL- Cholesterol
Test Strips II-43
Shield and Axis Merge to form Axis-Shield II-43
Baxter Spins Off Cardiovascular Division II-43

10. Focus on Select Global Players II-44
AccuTech, LLC (US) II-44
Axis-Shield Plc (UK) II-44
Biosite Inc. (US) II-45
Cholestech Corporation (US) II-45
Dade Behring, Inc. (US) II-45
Home Access Health II-46
Lifestream Technologies, Inc. (US) II-46
Roche Diagnostics (Switzerland) II-47

11. Global Market Perspective II-48
Table 9: World Recent Past, Current & Future Market Analysis
for Cholesterol & Other Cardiovascular Testing by Geographic
Region
US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America and Rest of World Independently
Analyzed with Annual Sales Figures in Million Units for Years
2000 through 2010 (includes corresponding Graph/Chart) II-48

Table 10: World 10-Year Perspective for Cholesterol & Other
Cardiovascular Testing by Geographic Region
Percentage
Breakdown of Unit Sales for US, Canada, Japan, Europe, Asia-
Pacific (excluding Japan), Latin America and Rest of World
Markets for Years 2000, 2005 & 2010 (includes corresponding
Graph/Chart) II-48

Table 11: World Recent Past, Current & Future Market Analysis
for Lipid Panel Test/Complete Lipid Profile Test by Geographic
Region -United States, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America, and Rest of World
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2000 through 2010 (includes corresponding
Graph/Chart) II-49

Table 12: World 10-Year Perspective for Lipid Panel Test/
Complete Lipid Profile Test by Geographic Region
Percentage
Breakdown of Unit Sales for US, Canada, Japan, Europe, Asia-
Pacific (excluding Japan), Latin America, and Rest of World
Markets for Years 2000, 2005 & 2010 (includes corresponding
Graph/Chart) II-49

Table 13: World Recent Past, Current & Future Market Analysis
for Total Cholesterol Testing by Geographic Region -United
States, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America, and Rest of World Independently Analyzed with
Annual Sales Figures in Million Units for Years 2000 through
2010 (includes corresponding Graph/Chart) II-50

Table 14: World 10-Year Perspective for Total Cholesterol
Testing by Geographic Region
Percentage Breakdown of Unit
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Markets for Years
2000, 2005 & 2010 (includes corresponding Graph/Chart) II-50

Table 15: World Recent Past, Current & Future Market Analysis
for HDL Cholesterol Testing by Geographic Region -United
States, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America, and Rest of World Independently Analyzed with
Annual Sales Figures in Million Units for Years 2000 through
2010 (includes corresponding Graph/Chart) II-51

Table 16: World 10-Year Perspective for HDL Cholesterol
Testing by Geographic Region
Percentage Breakdown of Unit
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Markets for Years
2000, 2005 & 2010 (includes corresponding Graph/Chart) II-51

Table 17: World Recent Past, Current & Future Market Analysis
for Apolipoprotein B Tests by Geographic Region -United
States, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America, and Rest of World Independently Analyzed with
Annual Sales Figures in Million Units for Years 2000 through
2010 (includes corresponding Graph/Chart) II-52

Table 18: World 10-Year Perspective for Apolipoprotein B
Tests by Geographic Region
Percentage Breakdown of Unit
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Markets for Years
2000, 2005 & 2010 (includes corresponding Graph/Chart) II-52

Table 19: World Recent Past, Current & Future Market Analysis
for Other Apolipoprotein Tests by Geographic Region -United
States, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America, and Rest of World Independently Analyzed with
Annual Sales Figures in Million Units for Years 2000 through
2010 (includes corresponding Graph/Chart) II-53

Table 20: World 10-Year Perspective for Other Apolipoprotein
Tests by Geographic Region
Percentage Breakdown of Unit
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Markets for Years
2000, 2005 & 2010 (includes corresponding Graph/Chart) II-53


III. MARKET

1. The United States III-1
A.Market Analysis III-1
Market Outlook III-1
Commanding A Third of the World’s Cholesterol
Testing Market III-1
Cardiovascular Market: Startling Statistics III-1
Table 21: Prevalence of Cardiovascular Disease (CVD) in
the US: Population by Disease Type (in 000s) (includes
corresponding Graph/Chart) III-2
Cholesterol Testing
NCEP Recommendations Spurs Potential III-2
Trends and Issues III-3
POC Lipid Profiling Flourishes under New Guidelines III-3
Need for Immediate and Accurate Heart Attack Diagnosis III-3
Awareness Brings Change III-3
Cardiovascular In Vitro Diagnostics: An Overview III-4
Point-of-Care Testing Market
An Overview III-4
Technological Developments Steer the Home Health Care Market III-4
Home Diagnostic Products Market: An Overview III-5
Home Cholesterol Testing Market
An Overview III-5
Table 22: US Recent Past, Current & Future Analysisfor
Home/ OTC Cholesterol Test Kits: Annual Sales Figures in
US$ Million for Years 2000 through2010 (includes
corresponding Graph/Chart) III-5
Key Players III-6
AccuTech, LLC III-6
Biosite Inc. III-6
Cholestech Corporation III-6
Dade Behring, Inc. III-7
Home Access Health III-7
Lifestream Technologies, Inc. III-8
Product Developments: Historic III-8
Product Launches III-9
Product Launches: Historic III-11
Strategic Developments III-13
Strategic Developments: Historic III-18
B.Market Analytics III-20
Table 23: US Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment
Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2000 through 2010 (includes corresponding Graph/Chart) III-20

Table 24: US 10-Year Perspective for Cholesterol & Other
Cardiovascular Testing by Product Segment
Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets
for 2000, 2005 & 2010 (includes corresponding Graph/Chart) III-20

2. Canada III-21
A.Market Analysis III-21
Market Outlook III-21
Strategic Developments III-21
B.Market Analytics III-22
Table 25: Canadian Recent Past, Current & Future Analysis
for Cholesterol & Other Cardiovascular Testing by Product
Segment
Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2000 through 2010 (includes corresponding Graph/
Chart) III-22

Table 26: Canadian 10-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment -
Percentage Breakdown of Unit Sales for Lipid Panel Test/
Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other
Apolipoprotein Tests Markets for 2000, 2005 & 2010
(includes corresponding Graph/Chart) III-23

3. Japan III-24
A.Market Analysis III-24
Market Outlook III-24
Leading the Volume Growth III-24
Home/OTC Cholesterol Testing Market III-24
Table 27: Japanese Recent Past, Current & Future Analysis
for Home/ OTC Cholesterol Test Kits Market: Annual Sales
Figures in US$ Million for Years 2000 through 2010
(includes corresponding Graph/Chart) III-24
Product Launches III-25
Strategic Corporate Development III-25
B.Market Analytics III-26
Table 28: Japanese Recent Past, Current & Future Analysis
for Cholesterol & Other Cardiovascular Testing by Product
Segment
Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2000 through 2010 (includes corresponding Graph/Chart) III-26

Table 29: Japanese 10-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment
Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
2000, 2005 & 2010 (includes corresponding Graph/Chart) III-26

4. Europe III-27
A.Market Analysis III-27
Market Outlook III-27
Germany Leads in Size and Growth III-27
Strategic Corporate Developments III-27
Point of Care Diagnostics Market Overview III-28
Table 30: European Home Point-of-Care (POC) Diagnostics
Market (2004): Annual Sales Estimates in US$ Million by
Country/ Region
Germany, France, Italy, Spain, United
Kingdom, and Rest of Europe lncludes corresponding Graph/
Chart) III-28
Home/OTC Cholesterol Testing Market in Western Europe III-28
Table 31: Western Europe Market for Home/ OTC Cholesterol
Test Kits- Recent Past, Current & Future Analysis: Annual
Sales Figures in US$ Million for Years 2000 through 2010
(includes corresponding Graph/Chart) III-28
B.Market Analytics III-29
Table 32: European Recent Past, Current & Future Analysis
for Cholesterol & Other Cardiovascular Testing by Geographic
Region
France, Germany, Italy, UK, Spain, Russia & Rest of
Europe Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2010
(includes corresponding Graph/Chart) III-29

Table 33: European 10-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Geographic Region -
Percentage Breakdown of Unit Sales for France, Germany,
Italy, UK, Spain, Russia & Rest of Europe Markets for 2000,
2005 & 2010 (includes corresponding Graph/Chart) III-29

Table 34: European Recent Past, Current & Future Analysis
for Cholesterol & Other Cardiovascular Testing by Product
Segment
Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2000 through 2010 (includes corresponding Graph/Chart) III-30

Table 35: European 10-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment
Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
2000, 2005 & 2010 (includes corresponding Graph/Chart) III-30

4a. France III-31
A.Market Analysis III-31
Market Outlook III-31
Cardiovascular Diagnostics Equipment Market
An Overview III-31
Functional Analysis Equipment Market
An Overview III-31
Factors Influencing Demand for Functional Analysis Equipment III-31
B.Market Analytics III-32
Table 36: French Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment
Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2000 through 2010 (includes corresponding Graph/Chart) III-32

Table 37: French 10-Year Perspective for Cholesterol & Other
Cardiovascular Testing by Product Segment
Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
2000, 2005 & 2010 (includes corresponding Graph/Chart) III-32

4b. Germany III-33
A.Market Analysis III-33
Market Outlook III-33
Strategic Corporate Development III-33
B.Market Analytics III-33
Table 38: German Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2000 through 2010 (includes corresponding Graph/Chart) III-33

Table 39: German 10-Year Perspective for Cholesterol & Other
Cardiovascular Testing by Product Segment
Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
2000, 2005 & 2010 (includes corresponding Graph/Chart) III-34

4c. Italy III-35
A.Market Analysis III-35
Market Outlook III-35
B.Market Analytics III-35
Table 40: Italian Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2000 through 2010 (includes corresponding Graph/Chart) III-35

Table 41: Italian 10-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment
Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
2000, 2005 & 2010 (includes corresponding Graph/Chart) III-36

4d. United Kingdom III-37
A.Market Analysis III-37
Market Outlook III-37
Axis-Shield Plc
A key Player III-37
Product Launches III-37
B.Market Analytics III-38
Table 42: UK Recent Past, Current & Future Analysis for
Cholesterol & Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2000 through 2010 (includes corresponding Graph/
Chart) III-38

Table 43: UK 10-Year Perspective for Cholesterol & Other
Cardiovascular Testing by Product Segment
Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
2000, 2005 & 2010 (includes corresponding Graph/Chart) III-38

4e. Spain III-39
A.Market Analysis III-39
Market Outlook III-39
B.Market Analytics III-39
Table 44: Spanish Recent Past, Current & Future Analysis
for Cholesterol & Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2000 through 2010 (includes corresponding Graph/Chart) III-39

Table 45: Spanish 10-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment
Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
2000, 2005 & 2010 (includes corresponding Graph/Chart) III-40

4f. Russia III-41
A.Market Analysis III-41
Market Outlook III-41
B.Market Analytics III-41
Table 46: Russian Recent Past, Current & Future Analysis
for Cholesterol & Other Cardiovascular Testing by Product
Segment
Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2000 through 2010 (includes corresponding Graph/Chart) III-41

Table 47: Russian 10-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment
Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
2000, 2005 & 2010 (includes corresponding Graph/Chart) III-42

4g. Rest of Europe III-43
A.Market Analysis III-43
Market Outlook III-43
Austria
Healthy Outlook III-43
Health Care System in Poland
An Overview III-43
Medical Equipment Market Overview III-43
Production of Medical Equipment III-44
Roche Diagnostics
A Key Player III-44
Product Launches
Historic III-44
Product Launch III-45
Strategic Corporate Development III-45
B.Market Analytics III-46
Table 48: Rest of Europe Market for Cholesterol & Other
Cardiovascular Testing
Recent Past, Current & Future
Analysis by Product Segment for Lipid Panel Test/Complete
Lipid Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Test Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2000 through 2010 (includes corresponding
Graph/Chart) III-46

Table 49: Rest of Europe 10-Year Perspective for Cholesterol
& Other Cardiovascular Testing by Product Segment -
Percentage Breakdown of Unit Sales for Lipid Panel Test/
Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets for 2000, 2005 & 2010 (includes corresponding
Graph/Chart) III-46

5. Asia-Pacific III-47
A.Market Analysis III-47
Market Outlook III-47
Chinese Diagnostic Equipment Market III-47
Underdeveloped Health Care System III-47
Dominance of US Companies III-47
Opportunities Abound III-48
Cardiovascular Equipment/Devices Market in Hong Kong III-48
Categorization of Health Care Services III-48
Imports Scenario III-49
B.Market Analytics III-49
Table 50: Asia-Pacific Market for Cholesterol & Other
Cardiovascular Testing
Recent Past, Current & Future
Analysis by Product Segment for Lipid Panel Test/Complete
Lipid Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Test Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2000 through 2010 (includes corresponding
Graph/Chart) III-49

Table 51: Asia-Pacific 10-Year Perspective for Cholesterol &
Other Cardiovascular Testing by Product Segment
Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
2000, 2005 & 2010 (includes corresponding Graph/Chart) III-50

6. Latin America III-51
A.Market Analysis III-51
B.Market Analytics III-51
Table 52: Latin American Market for Cholesterol & Other
Cardiovascular Testing
Recent Past, Current & Future
Analysis by Product Segment for Lipid Panel Test/
CompleteLipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Test Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2000 through 2010
(includes corresponding Graph/Chart) III-51

Table 53: Latin American 10-Year Perspective for Cholesterol
& Other Cardiovascular Testing by Product Segment -
Percentage Breakdown of Unit Sales for Lipid Panel Test/
Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets for 2000, 2005 & 2010 (includes corresponding
Graph/Chart) III-52

7. Rest of World III-53
A.Market Analysis III-53
Market Outlook III-53
B.Market Analytics III-53
Table 54: Rest of World Market for Cholesterol & Other
Cardiovascular Testing
Recent Past, Current & Future
Analysis by Product Segment for Lipid Panel Test/Complete
Lipid Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Test Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2000 through 2010 (includes corresponding
Graph/Chart) III-53

Table 55: Rest of World 10-Year Perspective for Cholesterol
& Other Cardiovascular Testing by Product Segment -
Percentage Breakdown of Unit Sales for Lipid Panel Test/
Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets for 2000, 2005 & 2010 (includes corresponding
Graph/Chart) III-54


IV. COMPETITION

1. Abbott Diagnostics Division of Abbott Laboratories (USA) IV-1
2. Accu-Stat Diagnostics (USA) IV-12
3. Accutech LLC (USA) IV-13
4. Akers Biosciences, Inc. (USA) IV-14
5. Alfa Wassermann SpA (Italy) IV-16
Alfa Wassermann, Inc. (USA) IV-17
6. Analox Instruments Ltd. (UK) IV-18
Analox Instruments USA, Inc. (USA) IV-20
7. Apex Biotechnology Corporation (Taiwan) IV-22
8. Atherotech, Inc. (USA) IV-23
9. Axis-Shield PLC (UK) IV-25
Table 56: Annual Sales Analysis: 2004-2005 (In £
million) IV-25

Table 57: Annual Sales Analysis by Segment: 2004-2005
(In £ million) IV-25
10. Bio-Rad Laboratories, Inc. (USA) IV-28
Table 58: First Quarter Sales Analysis: 2005-2006 (Q1)
(In US$ million) IV-29

Table 59: First Quarter Sales Analysis by Segment:
2005-2006 (Q1) (In US$ million) IV-29

Table 60: Annual Sales Analysis: 2004-2005 (In US$
million) IV-30

Table 61: Quarterly Sales Analysis: 2004-2005 (In US$
million) IV-30

Table 62: Annual Sales Analysis by Product Segment:
2004-2005 (In US$ million) IV-30

Table 63: Annual Sales Analysis by Geographic Region:
2004-2005 (In US$ million) IV-30
11. Biosite, Inc. (USA) IV-40
Table 64: First Quarter Sales Analysis: 2005-2006 (Q1)
(In US$ million) IV-41

Table 65: Annual Sales Analysis: 2004-2005 (In US$
million) IV-41

Table 66: Quarterly Sales Analysis: 2004-2005 (In US$
million) IV-41
12. Capricorn Products, Inc. (USA) IV-45
13. Chematics, Inc. (USA) IV-46
14. Chemicon International, Inc. (USA) IV-47
15. Cholestech Corporation (USA) IV-52
Table 67: First Quarter Sales Analysis: 2006-2007 (Q1)
(In US$ million) IV-52

Table 68: Annual Sales Analysis: 2004-2006 (In US$
million) IV-53
16. Cliniqa Corporation (USA) IV-55
17. Dade Behring, Inc. (USA) IV-57
Table 69: Half Yearly Sales Analysis: 2005-2006 (H1)
(In US$ million) IV-58

Table 70: Half Yearly Sales Analysis by Segment: 2005-
2006 (H1) (In US$ million) IV-59
Table 71: Half Yearly Sales Analysis by Geographical
Region: 2005-2006 (H1) (In US$ million) IV-59
Table 72: Annual Sales Analysis: 2004-2005 (In US$
million) IV-59

Table 73: Quarterly Sales Analysis: 2004-2005 (In US$
million) IV-59

Table 74: Annual Sales Analysis by Segment: 2004-2005
(In US$ million) IV-60

Table 75: Annual Sales Analysis By Geographical Region:
2004-2005 (In US$ million) IV-60
18. Denka Seiken Co., Ltd. (Japan) IV-81
19. Diagnostic Chemicals Limited (Canada) IV-87
20. Equal Diagnostics (USA) IV-89
21. Exocell, Inc. (USA) IV-90
22. Genzyme Corporation (USA) IV-91
Table 76: First Quarter Sales Analysis: 2005-2006 (Q1)
(In US$ billion) IV-94

Table 77: Annual Sales Analysis: 2004-2005 (In US$
billion) IV-94

Table 78: Quarterly Sales Analysis: 2004-2005 (In US$
billion) IV-94

Table 79: Annual Sales Analysis by Segment: 2004-2005
(In US$ billion) IV-95

Table 80: Annual Sales Analysis by Geographic Region:
2004-2005 (In US$ billion) IV-95
23. Helena Laboratories, Inc. (USA) IV-100
24. Hemagen Diagnostics, Inc. (USA) IV-103
Table 81: Half-Yearly Sales Analysis: 2005-2006 (H1)
(In US$ million) IV-103

Table 82: Half-Yearly Sales Analysis by Geographic
Region: 2005-2006 (H1) (In US$ million) IV-103

Table 83: Annual Sales Analysis: 2004-2005 (In US$
million) IV-104

Table 84: Annual Sales Analysis by Geographic Region:
2004-2005 (In US$ million) IV-104
25. Home Access Health Corporation (USA) IV-105
26. Invitrogen Corporation (USA) IV-106
Table 85: Half Yearly Sales Analysis: 2005-2006 (H1)
(In US$ million) IV-107

Table 86: Half Yearly Sales Analysis by Quarter: 2005-
2006 (H1) (In US$ million) IV-107

Table 87: Annual Sales Analysis: 2004-2005 (In US$
million) IV-107

Table 88: Quarterly Sales Analysis: 2004-2005 (In US$
million) IV-108

Table 89: Annual Sales Analysis by Segment: 2004-2005
(In US$ million) IV-108
27. Johnson & Johnson (USA) IV-115
Table 90: First Quarter Sales Analysis: 2005-2006 (Q1)
(In US$ billion) IV-116

Table 91: First Quarter Sales Analysis by Segment:
2005-2006 (Q1) (In US$ billion) IV-117
Table 92: First Quarter Sales Analysis by Geographic
Region: 2005-2006 (Q1) (In US$ billion) IV-117
Ortho-Clinical Diagnostics (USA) IV-123
28. Kamiya Biomedical Company (USA) IV-125
29. Lifestream Technologies, Inc. (USA) IV-127
30. Liposcience, Inc. (USA) IV-129
31. Medical Home Products, Inc. (USA) IV-131
32. Nanogen, Inc. (USA) IV-132
Table 93: First Quarter Sales Analysis: 2005-2006 (Q1)
(In US$ million) IV-132

Table 94: Annual Sales Analysis: 2004-2005 (In US$
million) IV-133

Table 95: Quarterly Sales Analysis: 2004-2005 (In US$
million) IV-133
33. Olympus Europa GmbhH (Germany) IV-136
34. Polymer Technology Systems, Inc. (USA) IV-138
35. Quantimetrix Corporation (USA) IV-140
36. Response Biomedical Corporation (Canada) IV-143
Table 96: Annual Sales Analysis: 2004-2005 (In Can$
million) IV-143

Table 97: Quarterly Sales Analysis: 2004-2005 (In Can$
million) IV-144
37. Roche Diagnostics (Schweiz) AG (Switzerland) IV-146
Roche Diagnostics Corporation (USA) IV-149
Roche Diagnostics India Pvt., Ltd. (India) IV-150
38. Siemens Medical Solutions (USA) IV-152
39. Skylight Biotech, Inc. (Japan) IV-154
40. Source Scientific, LLC (USA) IV-155
41. Terumo Corporation (Japan) IV-156
Table 98: Annual Sales Analysis: 2004-2005 (In ¥
million) IV-156

Table 99: Annual Sales Analysis by Segment: 2004-2005
(In ¥ million) IV-156
Terumo Medical Corporation (USA) IV-161
Terumo Cardiovascular Systems Corporation (USA) IV-161
42. The Binding Site Ltd. (UK) IV-163
43. Wako Chemicals USA, Inc. (USA) IV-166



Companies Mentioned - Abbott Diagnostics (USA) - Accutech LLC (USA) - Alfa Wassermann SpA (Italy) - Analox Instruments, Ltd (UK) - Apex Biotechnology Corporation (Taiwan) - Atherotech, Inc (USA) - Axis-Shield PLC (UK) - Bio-Rad Laboratories, Inc (USA) - Biosite, Inc (USA) - Capricorn Products, Inc (USA) - Chematics, Inc (USA) - Chemicon International, Inc (USA) - Cholestech Corporation (USA) - Cliniqa Corporation (USA) - Dade Behring, Inc (USA) - Denka Seiken Co, Ltd (Japan) - Diagnostic Chemicals Limited (Canada) - Equal Diagnostics (USA) - Exocell, Inc (USA) - Genzyme Corporation (USA) - Helena Laboratories, Inc (USA) - Hemagen Diagnostics, Inc (USA) - Home Access Health Corporation (USA) - Invitrogen Corporation (USA) - Johnson & Johnson (USA) - Kamiya Biomedical Co (USA) - Lifestream Technologies, Inc (USA) - Medical Innovations International, Inc (USA) - Nichols Institute Diagnostics (USA) - Polymer Technology Systems, Inc (USA) - Quantimetrix Corporation (USA) - Roche Diagnostics (Schweiz) AG (Switzerland) - Terumo Corporation (Japan) - The Binding Site Ltd (UK) - Wako Chemicals USA, Inc (USA)


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