Flow Cytometry - Global Strategic Business Report

This report analyzes the worldwide markets for Flow Cytometry in US$ Million. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, and Latin America. Annual estimates and forecasts are provided for the period 2010 through 2018. A six-year historic analysis is also provided for these markets. The report profiles 39 companies including many key and niche players such as Advanced Analytical Technologies, Inc., Amnis Corporation, Bangs Laboratories, Inc., Beckman Coulter, Inc., Becton, Dickinson and Company, Accuri Cytometers, Inc., Becton Dickinson India Pvt. Ltd., Cytek Development, Inc., eBioscience, Inc., Life Technologies Corporation, Luminex Corp., Merck Millipore, Partec GmbH, PointCare Technologies, Inc., Sony Biotechnology, Inc., and TTP LabTech Ltd. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain.

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I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-2
Quantitative Techniques & Analytics I-3
Product Definition and Scope of Study I-3
Flow Cytometers I-3
Consumables I-3

II. Executive Summary

1. INDUSTRY OVERVIEW AND OUTLOOK II-1
A Primer II-1
Current & Future Analysis II-1
Growth Barriers II-2
Research & Clinical Laboratories - Largest End-Use Segments II-2
Instrumentation and Reagents - Major Revenue Generators II-2
Technological Advances Boost Cytometric System Sales II-2
Large-Scale Screening Operations - Untapped Domain II-2

2. COMPETITIVE SCENARIO II-4
Table 1: Leading Players in the Global Flow Cytometers Market
(2011): Percentage Breakdown of Value Sales for Becton
Dickinson and Company (BD), Danaher/Beckman Coulter, and
Others (includes corresponding Graph/Chart) II-4

Table 2: Select Flow Cytometers Offered by Leading Players II-5
Leading Software Providers II-5
Flow Cytometry Data Analysis - Related Software by Select
Companies II-6

3. FLOW CYTOMETRY - AN INSIGHT II-7
Introduction to Flow Cytometry II-7
Bulk Analysis II-8
Single Cell Analysis II-8
Background and Development II-8
Flow Cytometry Products II-8
Consumables/Reagents II-8
Flow Cytometers II-9
Fluidics System II-9
Optical System II-9
Electronics System II-10
Fluorescence II-10
Light Scatter II-10
Brief Overview of Flow Cytometry Procedure II-10
Benefits of Flow Cytometer II-10

4. TECHNOLOGY OVERVIEW II-12
Laser Scanning Cytometry - Fundamental Breakthrough II-12
Microfabricated Fluorescence-Activated Cell Sorter II-13
Image Cytometry - Complementary Technique II-13
New Flow Cytometers from Japanese and American Scientists II-14

5. AREAS OF APPLICATION II-15
Versatile Use II-15
Table 3: Global Flow Cytometers Market (2011): Percentage
Breakdown of Value Sales by End-Use Industry - Academia,
Hospitals & Clinics, Contract Research Organization (CRO),
Government Research, and Others (includes corresponding
Graph/Chart) II-15
Clinical Applications II-15
Research Applications II-16
Drug Discovery II-16
Biomedical Research II-16
Fetal Cell Separation II-17
Stem Cell Sorting II-17
Marine Biology and Environmental Sciences II-17
Microbiology II-17

6. PRODUCT INTRODUCTIONS/INNOVATIONS II-18
Becton, Dickinson Introduces BD FACSJazz Cell Sorting System II-18
Beckman Coulter Life Sciences Upgrades Gallios Flow Cytometers
with 561 NM Laser Option II-18
Partec Introduces CyFlow Cube 6 and CyFlow Cube 8 Flow Cytometers II-18
Diagnostic Chips Launches Flow Cytometer Lab-on-a-Chip Device II-19
Bangs Laboratories Launches SureCount™ Particle Count Standards II-19
Bangs Laboratories Launches New Flow Cytometry Products II-19
BD Biosciences Introduces New Flexible Seven Laser Flow
Cytometry System II-20
iCyt Mission Technology Introduces SYNERGY and ECLIPSE II-20
BD Biosciences Introduces BD FACSAria-III Optical Flow Cytometer II-21
BD Biosciences Introduces BD LSRFortessa™ Cell Analyzer II-21

7. PRODUCT INNOVATIONS/LAUNCHES IN RECENT PAST - A PERSPECTIVE
BUILDER II-22
Miltenyi Biotec Introduces MACSQuant analyzer II-22
Amnis Introduces ImageStreamX II-22
Beckman Coulter Rolls Out Gallios Flow Cytometer II-22
Applied Biosystems Unveils Acoustic Focusing Cytometer II-22
Union Biometrica Launches Large Particle Flow Cytometers II-23
Millipore Unveils Guava easyCyte Flow Cytometer II-23
Beckman Coulter Rolls out New Flow Cytometer II-23
Beckman Coulter Introduces Kaluza Flow Cytometry Analysis
Software II-24
BD Biosciences Introduces BD FACSLink™ LIS Interface Solution
in US II-24
Beckman Coulter Combines Quanta™ SC MPL with Robotics II-24
BD Biosciences Introduces BD FACSAria™ II II-25
Beckman Coulter Launches Q-Check Program II-25
Millipore Launches FlowCellect™ Chemokine Receptor Surface
Expression Quantification Kits II-25
Millipore Launches FlowCellect Kits II-26
Accuri Cytometers Introduces Csampler II-26
Applied Cytometry Introduces VenturiOne Software II-26
Millipore Unveils a Series of Benchtop Flow Cytometry Systems II-26
Accuri Cytometers Rolls Out Accuri C6 Flow Cytometer System II-27

8. RECENT INDUSTRY ACTIVITY II-28
BD Takes Over Accuri Cytometers II-28
Beckman Coulter Acquires Blue Ocean Biomedical II-28
Danaher Acquires Beckman Coulter II-28
Merck Millipore Enters into Agreement to Take Over Amnis II-28
Merck Takes Over Millipore II-29
Sony Acquires iCyt Mission Technology II-29
IncellDx Signs Deal with Accuri II-29
BD Biosciences Signs Deal with ReaMetrix II-30

9. CORPORATE ACTIVITY IN RECENT PAST - A PERSPECTIVE BUILDER II-31
Millipore Takes Over Guava Technologies II-31
Dako Reagent Partnership Division and Fisher HealthCare Sign
Agreement II-31
Beckman Coulter Collaborates with Propel Labs II-31
Beckman to Market CompuCyte Cytometers II-31
BD Biosciences Purchases Cytopeia II-32
Gene Company Inks Agreement with Amnis II-32
Guava Technologies Enters into Agreement with Hudson Control II-32
Accuri Cytometers and De Novo Software Sign Licensing Agreement II-33
Guava Technologies Enters into Partnership with Millipore II-33
Invitrogen Takes Over Acoustic Cytometry Systems II-33

10. FOCUS ON SELECT GLOBAL PLAYERS II-34
Advanced Analytical Technologies, Inc. (US) II-34
Amnis Corporation (US) II-34
Bangs Laboratories, Inc. (US) II-34
Beckman Coulter, Inc. (US) II-34
Becton, Dickinson and Company (US) II-35
Accuri Cytometers, Inc. (US) II-36
Becton Dickinson India Pvt. Ltd II-36
Cytek Development, Inc. (US) II-36
eBioscience, Inc. (US) II-37
Life Technologies Corporation (US) II-37
Luminex Corp. (US) II-37
Merck Millipore (Germany) II-37
Partec GmbH (Germany) II-38
PointCare Technologies, Inc. (US) II-38
Sony Biotechnology, Inc. (US) II-38
TTP LabTech Ltd. (The United Kingdom) II-39

11. GLOBAL MARKET PERSPECTIVE II-40
Table 4: World Recent Past, Current & Future Analysis for Flow
Cytometry by Geographic Region - US, Canada, Japan, Europe,
Asia-Pacific and Latin America Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2010
through 2018 (includes corresponding Graph/Chart) II-40

Table 5: World Historic Review for Flow Cytometry by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific,
and Latin America Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2004 through 2009
(includes corresponding Graph/Chart) II-41

Table 6: World 15-Year Perspective for Flow Cytometry by
Geographic Region - Percentage Breakdown of Value Sales for
US, Canada, Japan, Europe, Asia-Pacific, and Latin America
Markets for Years 2004, 2011 & 2018 (includes corresponding
Graph/Chart) II-42

III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
Current & Future Analysis III-1
An Insight III-1
Table 7: Leading Players in the US Flow Cytometry Market
(2011): Percentage Breakdwon of Sales for Becton Dickinson,
Beckman Coulter, and Others (includes corresponding
Graph/Chart) III-1
Product Launches III-1
Strategic Corporate Developments III-4
Key Regional Players III-7
B.Market Analytics III-11
Table 8: US Recent Past, Current & Future Analysis for Flow
Cytometry Market - Annual Sales Figures in US$ Million for
Years 2010 through 2018 (includes corresponding Graph/Chart) III-11

Table 9: US Historic Review for Flow Cytometry Market -
Annual Sales Figures in US$ Million for Years 2004 through
2009 (includes corresponding Graph/Chart) III-12

2. CANADA III-13
Market Analysis III-13
Table 10: Canadian Recent Past, Current & Future Analysis
for Flow Cytometry Market - Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-13

Table 11: Canadian Historic Review for Flow Cytometry Market
- Annual Sales Figures in US$ Million for Years 2004 through
2009 (includes corresponding Graph/Chart) III-14

3. JAPAN III-15
Market Analysis III-15
Table 12: Japanese Recent Past, Current & Future Analysis
for Flow Cytometry Market - Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-15

Table 13: Japanese Historic Review for Flow Cytometry Market
- Annual Sales Figures in US$ Million for Years 2004 through
2009 (includes corresponding Graph/Chart) III-16

4. EUROPE III-17
Market Analysis III-17
Table 14: European Recent Past, Current & Future Analysis
for Flow Cytometry by Geographic Region - France, Germany,
Italy, UK, and Rest of Europe Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2010
through 2018 (includes corresponding Graph/Chart) III-18

Table 15: European Historic Review for Flow Cytometry by
Geographic Region - France, Germany, Italy, UK, and Rest of
Europe Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2004 through 2009 (includes
corresponding Graph/Chart) III-19

Table 16: European 15-Year Perspective for Flow Cytometry by
Geographic Region - Percentage Breakdown of Value Sales for
France, Germany, Italy, UK, and Rest of Europe Markets for
Years 2004, 2011 & 2018 (includes corresponding Graph/Chart) III-20

4a. FRANCE III-21
Market Analysis III-21
Table 17: French Recent Past, Current & Future Analysis for
Flow Cytometry Market - Annual Sales Figures in US$ Million
for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-21

Table 18: French Historic Review for Flow Cytometry Market -
Annual Sales Figures in US$ Million for Years 2004 through
2009 (includes corresponding Graph/Chart) III-22

4b. GERMANY III-23
A.Market Analysis III-23
Product Launches III-23
Select Key Players III-24
B.Market Analytics III-25
Table 19: German Recent Past, Current & Future Analysis for
Flow Cytometry Market - Annual Sales Figures in US$ Million
for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-25

Table 20: German Historic Review for Flow Cytometry Market -
Annual Sales Figures in US$ Million for Years 2004 through
2009 (includes corresponding Graph/Chart) III-26

4c. ITALY III-27
Market Analysis III-27
Table 21: Italian Recent Past, Current & Future Analysis for
Flow Cytometry Market - Annual Sales Figures in US$ Million
for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-27

Table 22: Italian Historic Review for Flow Cytometry Market
- Annual Sales Figures in US$ Million for Years 2004 through
2009 (includes corresponding Graph/Chart) III-28

4d. THE UNITED KINGDOM III-29
A.Market Analysis III-29
Product Launch III-29
Select Key Player III-29
B.Market Analytics III-30
Table 23: UK Recent Past, Current & Future Analysis for Flow
Cytometry Market - Annual Sales Figures in US$ Million for
Years 2010 through 2018 (includes corresponding Graph/Chart) III-30

Table 24: UK Historic Review for Flow Cytometry Market -
Annual Sales Figures in US$ Million for Years 2004 through
2009 (includes corresponding Graph/Chart) III-31

4e. REST OF EUROPE III-32
Market Analysis III-32
Table 25: Rest of Europe Recent Past, Current & Future
Analysis for Flow Cytometry Market - Annual Sales Figures in
US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-32

Table 26: Rest of Europe Historic Review for Flow Cytometry
Market - Annual Sales Figures in US$ Million for Years 2004
through 2009 (includes corresponding Graph/Chart) III-33

5. ASIA-PACIFIC III-34
A.Market Analysis III-34
Current & Future Analysis III-34
India III-34
Table 27: Flow Cytometry Market in India (2010): Percentage
Breakdown of Sales by End-Use Industry - Life Sciences,
Clinical Research and Pharmaceutical (includes
corresponding Graph/Chart) III-34
Key Player III-35
B.Market Analytics III-36
Table 28: Asia-Pacific Recent Past, Current & Future
Analysis for Flow Cytometry Market - Annual Sales Figures in
US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-36

Table 29: Asia-Pacific Historic Review for Flow Cytometry
Market - Annual Sales Figures in US$ Million for Years 2004
through 2009 (includes corresponding Graph/Chart) III-37

6. LATIN AMERICA III-38
Market Analysis III-38
Table 30: Latin American Recent Past, Current & Future
Analysis for Flow Cytometry Market - Annual Sales Figures in
US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-38

Table 31: Latin American Historic Review for Flow Cytometry
Market - Annual Sales Figures in US$ Million for Years 2004
through 2009 (includes corresponding Graph/Chart) III-39

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 39 (including Divisions/Subsidiaries - (61)

The United States (34)
Canada (1)
Japan (2)
Europe (14)
- France (1)
- Germany (4)
- The United Kingdom (6)
- Rest of Europe (3)
Asia-Pacific (Excluding Japan) (9)
Latin America (1)

Defined as a method of examining physical and chemical characteristics of cells or other biological particles, flow cytometry combines optical and fluorescence detection techniques with specialized fluidics, electronics and computer technology. Biological particles including cell subsets, DNA, cells, bacteria and surface antigens are identified by fluorescent labeling of extra or intracellular markers using marker-specific antibodies. Flow cytometry is used in clinical as well as research settings, for the analysis of both fixed and live samples of cells. In clinical settings, flow cytometry is used for prognosis and diagnosis of diseases such as HIV and cancer, assessing organ transplants as well as optimization of therapy. In research settings, the technique is used in a number of applications including RNA/DNA analysis, cell viability assays, drug resistance profiling in malignancies, signal transduction assays, immunophenotyping and cell viability assays among others. The technology is also used in several other research applications such as drug discovery, stem cell sorting, marine biology and environmental sciences, and microbiology.

Presently, the global demand for small-sized, robust and high throughput flow cytometers designed for use in a number of clinical and research applications is dominant. Growth drivers expected to propel the flow cytometry market include imminent prospects in immunology, biochemistry, microbiology, cytogenetics, chemical engineering, agronomy, molecular biology, and cytology applications. Also, innovations in the areas of stem cell research, monoclonal antibodies, marine biology, computer science, electronics and fluorochrome chemistry are likely to encourage market growth.

Long-term growth in the market would stem from development of next generation, point-of-care, compact systems. In terms of sophistication, newer integrated systems are increasingly incorporating innovative features, functions, and applications. Newer instruments from leading players designed to meet the high productivity requirements of researchers feature sorting rates of up to 70,000 events/second. Several modern cytometers are equipped with varying fluorescence detectors and lasers, which enable labeling of multiple antibodies. A few recently launched instruments are also capable of taking digital images of individual cells. Despite the rapid growth forecast, lack of awareness is the main drawback for flow cytometers. Though a number of technologically advanced flow cytometers are available in the market, several end-users are still not aware of the upgraded versions.

As stated by the new market research report on Flow Cytometry, the US represents the largest regional market for Flow Cytometers accounting for a majority share in the revenues generated in the global market. Asia-Pacific represents the fastest growing regional market with annual revenue from the region exhibiting a CAGR of about 11.6% over the analysis period. Despite being a relatively small market, demand for advanced medical and analytical equipment is witnessing steady growth in countries such as India, driven by advances in biotechnology and pharmaceuticals sectors. The trend is exemplified by rise in imports of specific R&D equipment such as biotech and pharmaceutical R&D equipment, pharmaceuticals reference studies as well as certain life saving drugs and medical products.

Global Industry Analysts ©

- Advanced Analytical Technologies, Inc. (USA)
- Amnis Corporation (USA)
- Apogee Flow Systems (UK)
- Applied Cytometry Systems (UK)
- Bangs Laboratories, Inc. (USA)
- Beckman Coulter, Inc. (USA)
- Beckman Coulter Canada, Inc. (Canada)
- Becton, Dickinson and Company (USA)
- BD Biosciences (USA)
- Accuri Cytometers, Inc. (USA)
- BD Biosciences Division (Belgium)
- Becton Dickinson India Pvt., Ltd. (India)
- Clarient, Inc. (USA)
- CompuCyte Corporation (USA)
- Cytek Development, Inc. (USA)
- Cytobuoy BV (The Netherlands)
- Dako Denmark A/S (Denmark)
- Dako North America, Inc. (USA)
- Dako Cytomation Pty., Ltd. (Australia)
- Dako Reagent Partnership Division (UK)
- Dako UK Ltd. (UK)
- De Novo Software (USA)
- eBioscience, Inc. (USA)
- Fluid Imaging Technologies (USA)
- Furukawa Electric Co., Ltd.(Japan)
- Health Discovery Corporation (USA)
- Intellicyt Corporation (USA)
- Life Technologies Corporation (USA)
- Applied Biosystems, Inc. (USA)
- Invitrogen Corporation (USA)
- Luminex Corporation (USA)
- Marker Gene Technologies, Inc. (USA)
- Merck Millipore GmbH (Germany)
- EMD Millipore (USA)
- Miltenyi Biotec GmbH (Germany)
- Partec GmbH (Germany)
- Phoenix Flow Systems (USA)
- PointCare Technologies, Inc. (USA)
- Polysciences, Inc. (USA)
- R&D Systems, Inc. (USA)
- Roche Applied Science (USA)
- SanTung Instruments Co., Ltd. (Taiwan)
- Sony Biotechnology, Inc. (USA)
- Sysmex Corporation (Japan)
- Jinan Sysmex Medical Electronics Co., Ltd. (China)
- Sysmex (Thailand) Co., Ltd. (Thailand)
- Sysmex America, Inc. (USA)
- Sysmex Do Brasil Industria E Comercio Ltda (Brazil)
- Sysmex Europe GmbH (Germany)
- Sysmex France Sarl (France)
- Sysmex Hong Kong Ltd. (Hong Kong)
- Sysmex Malaysia Sdn Bhd (Malaysia)
- Sysmex Asia Pacific Pte., Ltd. (Singapore)
- Sysmex UK Ltd. (UK)
- Thermo Fisher Scientific, Inc. (USA)
- Transasia Bio-Medicals Ltd. (India)
- Tree Star, Inc. - FlowJo (USA)
- TTP Labtech Ltd. (UK)
- Union Biometrica, Inc. (USA)
- Vector Laboratories, Inc. (USA)
- Verity Software House (USA)