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Proteomics - Global Strategic Business Report Product Image

Proteomics - Global Strategic Business Report

  • Published: October 2012
  • Region: Global
  • 636 Pages
  • Global Industry Analysts, Inc

This report analyzes the worldwide markets for Proteomics in US$ Million by the following Product Segments: Expression Proteomics, Functional Proteomics, and Structural Proteomics. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, and Rest of World. Annual estimates and forecasts are provided for the period of 2010 through 2015. Also, a six-year historic analysis is provided for these markets. The report profiles 111 companies including many key and niche players such as ActivX Biosciences, Inc., Adnexus Therapeutics, Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Bruker Daltonics, Inc., Caprion Proteomics, Inc., Digilab Genomic Solutions, Inc., Dionex Corporation, GE Healthcare, Geneva Bioinformatics S.A., Hybrigenics SA, Life Technologies Corporation, Millipore Corp., PerkinElmer, Inc., Caliper Life Sciences, Shimadzu Biotech, Sigma-Aldrich Corporation, Thermo Fisher Scientific, Waters Corp., Xencor Inc., and Zyomyx, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain.

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I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-2
Quantitative Techniques & Analytics I-3
Product Definitions and Scope of Study I-3
Expression Proteomics I-3
Functional Proteomics I-3
Structural Proteomics I-4

II. Executive Summary

1. GLOBAL MARKET OVERVIEW II-1
Proteomics - The Current Spotlight II-1
Market Drivers II-1
Transition from Genomics to Proteomics II-1
Industrialization of Proteomics Research II-2
International Initiatives Light-up Proteomics Market II-2
Factors Limiting Market Growth II-2
Economic Recession Impact on the Life Sciences Industry in
Retrospect II-2
Biotechnology Sector - Affected by Collapse of Capital Market II-3
Tough Times for Market Participants II-3
Proteomics Technologies: Growing in Significance II-4
Transformation of Drug Discovery through Proteomics and Genomics II-5
Proteomics: A Critical Drug Discovery Tool II-5
China All Set To Play a Major Role in the Proteomics Industry II-6
Global Proteomics Sample Preparation Market - On a Growth Curve II-7
Challenges Facing Proteomics Sample Preparation Market II-7
Challenges Facing Proteomics Industry II-7
Protein Chemistry and its Complexities II-7
Integration of Data & Equipment II-7
Data Validation - A Burning Issue II-8
Standardization & Consistency - A Prime Concern II-8
Incomplete and Disorganized Data II-8

2. INDUSTRY COMPETITION II-9
Industry Participants II-9
Proteomics Market Worldwide: Competitive Landscape II-9
Proteomics Supplier Market II-9
Tool Providers: Leading the Proteomics Market II-10
Applied Biosystems-Invitrogenc Corporation Merger - A Key
Development II-10
Challenges Ahead II-11
Designing a Novel Business Model II-11
Role of Contract Research Organizations - All Set to Increase
in Proteomics II-11

3. PRODUCT AND TECHNOLOGY OVERVIEW II-12
Proteins, Proteome and Proteomics!!! - What are They? II-12
Proteomics - An Introduction II-12
Genesis of Proteomics II-13
Tales From Times Gone By II-13
Components of Proteomics II-13
Expression Proteomics II-13
Functional Proteomics II-14
Cell-map Proteomics II-14
Structural Proteomics II-14
Technologies and Proteomics II-14
Proteomics and Genomics II-15
Proteomics and Genomics: A Comparison II-15
Protein Production Pathway: From Gene Expression to
Functional Protein with Controls II-15
From Genomics to Proteomics II-16
Functional Genomics and Proteomics II-16
Push From Genomic Information II-17
An Insight into Proteomics Data Type and their
Characteristics / Features II-17
Standard Proteomics Approach II-17
Sample Preparation - Step I II-18
Protein Separation - Step II II-18
Protein Visualization II-18
Protein Expression Analysis-Step III II-18
Protein Identification - Step IV II-19
Data Storage and Processing - Step V II-19

4. OVERVIEW OF PROTEOMICS TECHNOLOGIES II-20
A Snapshot of Various Proteomics Tools II-20
An Insight into Various Proteomics Technologies and their
Application Areas II-20
Protein Separation II-20
2-Dimensional Gel Electrophoresis (2DGE) II-20
Protein Characterization II-22
Analysis of Protein Through Mass Spectrometry II-22
MS and Proteins II-22
Applications of MS II-23
Problems Associated with MS II-24
Types of Analyzers or Filters II-24
Y2H, Yeast 2-Hybrid System II-25
Protein Microarrays II-26
Chip Technology II-26
Microfluidic Applications II-27
Role of Bioinformatics in Proteomics II-27
Bioinformatics Applications and Tools in Proteomics II-27
Emerging Proteomics Technologies II-29
MudPIT II-29
ICAT II-29
Phage Display Technique II-30
Advanced Proteomics Technologies: Structural Analysis Tools II-30
X-ray Crystallography II-30
Nuclear Magnetic Resonance (NMR) II-30
In silico Modelling II-31
Physicochemical Factors Constraining Metabolic Functions II-31

5. END-USE APPLICATION AREAS II-32
Proteomics in Drug and Diagnostic Discovery II-33
Proteomics and Drug Discovery II-33
Protein Microarrays: A New Tool for the Development of
Pharmaceuticals II-34
Proteomic Approaches Gain Prominence in Cancer Drug Discovery II-34
Advancements in Proteomics Bring Biomarkers into Limelight II-35

6. NEW PRODUCT SOLUTIONS/ DEVELOPMENTS II-36
Applied Biomics Introduces Global Protein Post- Translational
Modification II-36
AB SCIEX Launches New Column Chips II-36
Applied Biomics Introduces New Mass Spectrometry Service II-37
Norton Scientific Introduces Novel Specialist Applications
Development Laboratory Service II-37
Gentel Biosciences Introduces APiXTM Disease Profiling Kit II-38
Integromics Introduces OmicsHub Proteomics 2.0 II-38
Bruker Introduces amaZon Speed Ion Trap Mass Spectrometers II-39
Applied Biomics Introduces iTRAQ Service for Proteomics Research II-39
Norton Scientifc Company Introduces New Lab Support Service
for Rapid RNA/DNA and Protein Measurement II-39
Bruker Launches MALDI BiotargetTM II-40
Thermo Fisher Launches UHLPC System II-40
Kinexus Introduces Human Gene Online TranscriptoNET KnowledgeBase II-41
Bruker Launches PRIME Integrated Proteomics Solution II-42
Applied Biosystems Launches LS*LIMS Laboratory Automation
Technology for Proteomics and Genomics II-42
Kinexus Bioinformatics Introduces Online KiNET-AM Proteomics
DataBase II-42
Bruker Rolls Out CaptiveSpray Electrospray Ion Source for
Proteomics Applications II-43
Thermo Fisher Launches New Capabilities for Performing
Proteomics Workflows II-43
National Cancer Institute Introduces Clinical Proteomic Tumor
Analysis Consortium for Cancer Studies II-44
KinaSorbTM' - New Kit for Kinase Enrichment II-45

7. PRODUCT INTRODUCTIONS/INNOVATIONS IN RECENT PAST - A
PERSPECTIVE BUILDER II-46
Gentel Biosciences Unveils Gentel Proteomics Multi-SystemTM II-46
caprotec bioanalytics Introduces Innovative caproKits II-46
Gentel Biosciences Introduces SilverQuant® Simian Pathogen
Array for Health Monitoring of Laboratory Animals II-46
Gentel Biosciences Introduces SilverQuant® Human Tumor
Profiling Kits II-46
Gentel Biosciences Introduces SilverQuant® Disease Profiling Kit II-47
Gentel Biosciences Introduces SilverQuant® View Detection Kits II-47
Gentel Biosciences Launches Proteomics Multi-System II-47
New England Peptide Introduces NEPTune™ Range of Proteomics
Reagents II-48
Applied Biomics Introduces NanoLC-MS/MS Service II-48
Life Technologies Introduces Magic Sample Processor for
Epigenetics, Proteomics Sample Preparation II-49
Integromics Introduces SeqSolve™ NGS Bioinformatics Analysis
Software II-50
Thermo Fisher Scientific Unveils Software Suite for Enhanced
Workflows in Proteomics II-50
Proxeon Introduces EASY-nLC II System for Improved
Productivity in Proteomics (Denmark) II-51
Gentel Biosciences Launches Proteomics Multi-System II-51
Arrayit Discovers New Proteomic Biomarkers II-52
Kinexus Bioinformatics Launches Peptide Development Facility II-52
Bruker Daltonics Unveils ultrafleXtreme™ MALDI-TOF/TOF Mass
Spectrometer II-52
Agilent Technologies Rolls Out HPLC-Chip II-53
Applied Biosystems and MDS Introduce AB SCIEX TOF/TOF™ 5800
System II-53
Applied Biomics Extends Proteomics Service Offerings II-54
AnaSpec Introduces Keratin Antibodies II-54
caprotec bioanalytics Unveils cAMP caproKit and SAH caproKit II-54
Huzhou Saierdi Biopharmaceutical Introduces Proteomic
Fingerprint Technology Test Kit II-54

8. RECENT INDUSTRY ACTIVITY II-55
Life Technologies Enters into Partnership with Sino Biological II-55
Proteome Sciences Signs Agreement with CHDI Foundation II-55
Waters Corp. Inks Agreement with Nonlinear Dynamics II-56
BioFocus Enters into Alliance with Activiomics II-56
Great Point Partners Divests Caprion Proteomics II-56
Glaxo Smith Kline Takes Over Cellzome II-57
Emerald BioSystems Changes Name to Emerald Bio II-57
Bruker Unveils Novel Nano-Advance UHPLC System II-57
Evotec Takes Over Kinaxo Biotechnologies II-58
Kinaxo Biotechnologies and AstraZeneca Sign Agreement II-58
Gentel Biosciences Takes Over Eppendorf's SilverQuant Trademark II-58
Thermo Fisher Takes Over Fermentas International II-58
KINAXO to Collaborate with Takeda II-59
Dualsystems and Bulldog Bio Signs Exclusive Marketing Agreement II-59
Novartis Enters into Agreement with SomaLogic II-59
Sage-N Inks Exclusive Pact With the U.S. Army II-59
Proteome Sciences Inks Agreement with Moffitt Cancer Center II-60
Gentel Biosciences Enters into Agreement with Oregon Health &
Science University II-60
Evotec OAI Forms Joint Venture with MeITec to Collaborate on
Drug Discovery Services II-60

9. CORPORATE ACTIVITY IN RECENT PAST - A PERSPECTIVE BUILDER II-61
MicroBioChips Merges with Biosystems II-61
Caprion Proteomics Acquires Biomarket Unit from PPD Biomarker
Discovery Sciences II-61
ICON Enters into Strategic Alliance with Proteome Sciences II-61
Gentel Enters into Partnership with RayBiotech for
SilverQuant® Chromogenic Detection Platform II-61
Trans-Hit Biomarkers Enters into Alliance with Caprion to
Deliver Proteome-Hit Services II-62
Proteoprep Enters into License Agreement with Sigma-Aldrich II-62
Activiomics Signs Technology Agreement with UCB for Proteomics
Platform(UK/Belgium) II-63
Expression Pathology Enters into Service Partnership with
Flagship for Tissue Proteomics Development II-63
National Cancer Institute Enters into MoU with AACC in
Proteomics Sector II-63
MGL Americas and ProFACT Proteomics Team Up for Biomarker
Discovery II-64
Thermo Fisher Scientific and Luxembourg Clinical Proteomics
Unit Form Collaboration (Luxembourg) II-64
Covance Unveils Discovery and Translational Services Division II-65
Thermo Fisher Scientific Takes Over Proxeon II-65
TriLink BioTechnologies and Nacalai USA Sign Distribution
Agreement II-65
Cell Biosciences Takes Over Alpha Innotech II-65
Eurogentec to Take Over Ana Spec II-66
Merck Takes Over Bangalore Genei II-66
Cell Biosciences Takes Over Protein Forest II-66
Microsoft to Acquire Rosetta Bio Software Assets II-67
CCMB and Bio-Rad India Sign MoU II-67
SAIC-Frederick and Sensor Technologies Ink Collaboration
Agreement II-67
NuSep Signs Purchase Agreement with BioInquire II-68
Intrinsic Bioprobes Bags Contract from NCI II-68
HORIBA Jobin Yvon Acquires GenOptics II-68
Gentel Biosciences Partners with Eprogen II-68
Bruker Daltonics Installs High-Field 15 Tesla and 12 Tesla
FTMS Systems at LUMC II-69
Genedata Extends Collaboration with Roche II-69
AliX Merges with Novalyst Discovery to form NovAliX II-70
BioPike and AnaSpec Sign Agreement II-70
Sigma-Aldrich Purchases Electrophoresis Business of NextGen
Sciences II-70
Fujifilm Purchases Additional Stake in Perseus Proteomics II-71
Sigma-Aldrich Buys Seppro® Depletion Technology and 700
Antibodies II-71
Oxford Gene Technology Purchases Sense Proteomic II-72
Center for Cancer Research Acquires Waters® UPLC/MS Systems II-72

10. FOCUS ON SELECT KEY PLAYERS II-74
ActivX Biosciences, Inc. (US) II-74
Adnexus Therapeutics (US) II-74
Agilent Technologies, Inc. (US) II-74
Bio-Rad Laboratories, Inc. II-74
Bruker Daltonics, Inc. (US) II-75
Caprion Proteomics, Inc. (Canada) II-75
Digilab Genomic Solutions, Inc. (US) II-76
Dionex Corporation (US) II-76
GE Healthcare (United Kingdom) II-76
Geneva Bioinformatics S.A. (Switzerland) II-76
Hybrigenics SA (France) II-76
Life Technologies Corporation (US) II-77
Millipore Corp. (US) II-77
PerkinElmer, Inc. (US) II-78
Caliper Life Sciences (US) II-78
Shimadzu Biotech (Japan) II-78
Sigma-Aldrich Corporation (US) II-78
Thermo Fisher Scientific (US) II-79
Waters Corp. (US) II-79
Xencor Inc. (US) II-80
Zyomyx, Inc. (US) II-80

11. GLOBAL MARKET PERSPECTIVE II-81
Table 1: World Recent Past, Current & Future Analysis for
Proteomics by Geographic Region - US, Canada, Japan, Europe
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2010 through 2018
(includes corresponding Graph/Chart) II-81

Table 2: World Historic Review for Proteomics by Geographic
Region - US, Canada, Japan, Europe and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) II-82

Table 3: World 15-Year Perspective for Proteomics by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe and Rest of World Markets for Years
2004, 2011 and 2018 (includes corresponding Graph/Chart) II-83

Table 4: World Recent Past, Current & Future Analysis for
Proteomics by Segment - Expression Proteomics, Functional
Proteomics and Structural Proteomics Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2010 through 2018 (includes corresponding Graph/Chart) II-84

Table 5: World Historic Review for Proteomics by Segment -
Expression Proteomics, Functional Proteomics and Structural
Proteomics Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2004 through 2009 (includes
corresponding Graph/Chart) II-85

Table 6: World 15-Year Perspective for Proteomics by Segment -
Percentage Breakdown of Dollar Sales for Expression
Proteomics, Functional Proteomics and Structural Proteomics
Markets for Years 2004, 2011 and 2018 (includes corresponding
Graph/Chart) II-86

12. GLOSSARY OF TERMS II-87
1-D, 2-D, 3-D II-87
Atmospheric Pressure Ionisation II-87
Electrophoresis II-87
Functional Genomics II-87
High-Throughput II-87
Liquid Chromatography (LC) II-87
Mass Spectrometry (MS) II-87
Matrix-Assisted Laser Desorption Ionisation (MALDI) II-87
Nuclear Magnetic Resonance II-88
X-ray Diffraction II-88
Yeast Two-Hybrid System II-88
2D-PAGE (Two-dimensional PolyAcrylamide Gel Electrophoresis) II-88
TOF (Time of Flight) II-88
Quadrupole II-88
Q-TOF (Quadrupole Time of Flight) II-88
ESI (Electrospray Ionisation) II-88

III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
Outlook III-1
Proteomics Sample Preparation Market III-1
New Product Developments III-1
Strategic Corporate Developments III-6
Select Key Players III-9
B.Market Analytics III-14
Table 7: The US Recent Past, Current & Future Analysis for
Proteomics Market Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-14

Table 8: The US Historic Review for Proteomics Market
Analyzed with Annual Sales Figures in US$ Million for Years
2004 through 2009 (includes corresponding Graph/Chart) III-15

2. CANADA III-16
A.Market Analysis III-16
Outlook III-16
New Product Developments III-16
Strategic Corporate Development III-18
Caprion Proteomics, Inc. - A Key Player III-18
B.Market Analytics III-19
Table 9: Canadian Recent Past, Current & Future Analysis for
Proteomics Market Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-19

Table 10: Canadian Historic Review for Proteomics Market
Analyzed with Annual Sales Figures in US$ Million for Years
2004 through 2009 (includes corresponding Graph/Chart) III-20

3. JAPAN III-21
A.Market Analysis III-21
Shimadzu Biotech - A Key Player III-21
B.Market Analytics III-21
Table 11: Japanese Recent Past, Current & Future Analysis
for Proteomics Market Analyzed with Annual Sales Figures in
US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-21

Table 12: Japanese Historic Review for Proteomics Market
Analyzed with Annual Sales Figures in US$ Million for Years
2004 through 2009 (includes corresponding Graph/Chart) III-22

4. EUROPE III-23
A.Market Analysis III-23
Outlook III-23
Proteomics Research in Europe - An Overview III-23
Table 13: European Proteomics Market (2011): Percentage
Breakdown of Deployment of Proteomics Technologies in
End-Use Segments - Research and Academic Institutions,
Pharmaceutical Companies and Clinical Laboratories
(includes corresponding Graph/Chart) III-24
Protein Identification Market III-24
Protein Separation Market III-24
Market Challenges III-25
Gaining Edge in the Proteomics Industry - Player Strategies III-25
European 2DE Market - Benefiting from Recession III-26
Review of Select Markets III-26
Germany III-26
The United Kingdom III-26
New Product Developments III-27
Strategic Corporate Developments III-28
Select Key Players III-30
B.Market Analytics III-31
Table 14: European Recent Past, Current & Future Analysis
for Proteomics by Geographic Region - France, Germany, UK
and Rest of Europe Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2010 through
2018 (includes corresponding Graph/Chart) III-31

Table 15: European Historic Review for Proteomics by
Geographic Region - France, Germany, UK and Rest of Europe
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2004 through 2009 (includes
corresponding Graph/Chart) III-32

Table 16: European 15-Year Perspective for Proteomics by
Geographic Region - Percentage Breakdown of Dollar Sales for
France, Germany, UK andRest of Europe Markets for Years
2004, 2011 and 2018 (includes corresponding Graph/Chart) III-33

5. REST OF WORLD III-34
A.Market Analysis III-34
Outlook III-34
Australia III-34
India III-34
Indian Scientific Research towards Functional Genomics and
Proteomics III-34
B.Market Analytics III-35
Table 17: Rest of World Recent Past, Current & Future
Analysis for Proteomics Market Analyzed with Annual Sales
Figures in US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-35

Table 18: Rest of World Historic Review for Proteomics
Market Analyzed with Annual Sales Figures in US$ Million for
Years 2004 through 2009 (includes corresponding Graph/Chart) III-36

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 111 (including Divisions/Subsidiaries - 128)

The United States (82)
Canada (4)
Japan (3)
Europe (39)
- France (3)
- Germany (10)
- The United Kingdom (13)
- Spain (1)
- Rest of Europe (12)

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