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Cancer Diagnostics with DNA Microarrays
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Description: |
This book is the first of its kind in dealing with direct clinical application of microarray data to oncology diagnosis, with the intention of speeding and specifying diagnosis, thus resulting in better treatment for cancer patients. Replete with examples and mini-cases, the book offers cancer researchers in private, pharmacologic, and governmental institutions, bomedical statisticians, and practicing oncologists concise, thoughtfully authored guidance on the use iof microarray data and analysis as clinical tools. Some research-level readers may find certain introductory and review somewhat superficial, but these can be skipped over if necessary, and there is much useful, detailed information provided to further the understanding of the many aspects of microarray technology that can be applied to medical diagnostics in oncology. |
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Contents: |
Preface Acknowledgments 1. Introduction to DNA Microarray Technology 2. Image Analysis 3. Basic Data Analysis 4. Visualization by Reduction of Dimensionality 5. Cluster Analysis 6. Molecular Classifiers for Cancer 7. Survival Analysis 8. Meta-Analysis 9. The Design of Probes 10. Software Issues and Data Formats 11. Breast Cancer 12. Leukaemia 13. Lymphoma 14. Lung Cancer 15. Bladder Cancer 16. Colon Cancer 17. Ovarian Cancer 18. Prostate Cancer 19. Melanoma 20. Brain Tumors 21. Organ or Tissue Specific Classification 22. Sample Collection and Stability References Index
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