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Cancer Diagnostics with DNA Microarrays


Description: This book is the first of its kind in dealing with direct clinical application of microarray data to oncology diagnosis, with the intention of speeding and specifying diagnosis, thus resulting in better treatment for cancer patients. Replete with examples and mini-cases, the book offers cancer researchers in private, pharmacologic, and governmental institutions, bomedical statisticians, and practicing oncologists concise, thoughtfully authored guidance on the use iof microarray data and analysis as clinical tools. Some research-level readers may find certain introductory and review somewhat superficial, but these can be skipped over if necessary, and there is much useful, detailed information provided to further the understanding of the many aspects of microarray technology that can be applied to medical diagnostics in oncology.


Contents: Preface
Acknowledgments

1. Introduction to DNA Microarray Technology
2. Image Analysis
3. Basic Data Analysis
4. Visualization by Reduction of Dimensionality
5. Cluster Analysis
6. Molecular Classifiers for Cancer
7. Survival Analysis
8. Meta-Analysis
9. The Design of Probes
10. Software Issues and Data Formats
11. Breast Cancer
12. Leukaemia
13. Lymphoma
14. Lung Cancer
15. Bladder Cancer
16. Colon Cancer
17. Ovarian Cancer
18. Prostate Cancer
19. Melanoma
20. Brain Tumors
21. Organ or Tissue Specific Classification
22. Sample Collection and Stability

References
Index



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