 |
Printer Friendly
Printed from http://www.researchandmarkets.com/reports/349360
Neurotransmitters and Neuromodulators: Handbook of Receptors and Biological Effects, 2nd Edition
|
Description: |
Neurosciences are one of the most dynamically developing fields within life and medical sciences. This is underlined by the 2000 Nobel Prize for Medicine/Physiology that has been awarded for pioneering research in neuroactive substances. Biological effects, production, and application of these substances are of extremely high pharmaceutical and biotechnological interest. Several book reviews for the first edition stated that this handbook offers a unique combination and presentation of data on neurotransmitters and neuromodulators. The second edition is completely updated and extended with new chapters on additional substances and methods. |
|
Contents: |
Preface for the Second Edition.
Preface for the First Edition.
1 Introduction.
1.1 Neuroactive Substances.
1.1.1 Neurotransmitters.
1.1.2 Neuromodulators.
1.2 Receptors and Transporters.
1.2.1 Ionotropic Receptors.
1.2.2 Metabotropic Receptors.
1.2.3 Receptor Regulation.
1.2.4 Transporters.
1.3 Distribution and Localization of Neurotransmitters and Neuromodulators.
1.4 The Blood–Brain Barrier.
1.5 Volume Transmission and Wiring Transmission.
2 Methods.
2.1 Bio- and Radioisotope Assays.
2.2 Microdialysis and Electrochemical Detection.
2.2.1 Microdialysis.
2.2.2 Electrochemical Detection.
2.3 Chromatography.
2.3.1 Affinity Chromatography.
2.3.2 High Performance Liquid Chromatography.
2.3.3 Proteomics: Multidimensional Protein Identification Technology.
2.4 Autoradiography.
2.5 Immunohistochemical Methods.
2.6 In situ Hybridization.
2.7 Staining and Neuroanatomical Tract Tracing.
2.8 Electrophysiology.
2.8.1 In vivo Recording.
2.8.2 In vitro Recording.
2.9 Behavioral Testing.
2.9.1 Classic Conditioning.
2.9.2 Operant Conditioning.
2.9.3 Further Behavioral Tests.
3 Neurotransmitters.
3.1 Acetylcholine.
3.1.1 General Aspects and History.
3.1.2 Localization Within the Central Nervous System.
3.1.3 Biosynthesis and Degradation.
3.1.4 Receptors and Signal Transduction.
3.1.5 Biological Effects.
3.1.6 Neurological Disorders and Neurogenerative Diseases.
3.2 Dopamine.
3.2.1 General Aspects and History.
3.2.2 Differentiation and Localization of the Dopaminergic System.
3.2.3 Biosynthesis and Degradation.
3.2.4 Release, Re-uptake and Degradation.
3.2.5 Receptors and Signal Transduction.
3.2.6 Biological Effects.
3.2.7 Neurological Disorders and Neurodegenerative Diseases.
3.3 _-Amino Butyric Acid.
3.3.1 General Aspects and History.
3.3.2 Localization Within the Central Nervous System.
3.3.3 Biosynthesis and Degradation.
3.3.4 GABA Transporters.
3.3.5 Receptors and Signal Transduction.
3.3.6 Biological Effects.
3.3.7 Neurological Disorders and Neurogenerative Diseases.
3.4 Glutamate and Aspartate.
3.4.1 General Aspects and History.
3.4.2 Localization Within the Central Nervous System.
3.4.3 Biosynthesis and Degradation.
3.4.4 Transporters.
3.4.5 Receptors and Signal Transduction.
3.4.6 Biological Effects.
3.4.7 Neurological Disorders and Neurodegenerative Diseases.
3.5 Glycine.
3.5.1 General Aspects and History.
3.5.2 Localization Within the Central Nervous System.
3.5.3 Biosynthesis and Degradation.
3.5.4 Receptors and Signal Transduction.
3.5.5 Biological Effects.
3.5.6 Neurological Disorders and Neurodegenerative Diseases.
3.6 Histamine.
3.6.1 General Aspects and History.
3.6.2 Localization Within the Central Nervous System.
3.6.3 Biosynthesis and Degradation.
3.6.4 Receptors and Signal Transduction.
3.6.5 Biological Effects.
3.6.6 Neurological Disorders and Neurodegenerative Diseases.
3.7 Norepinephrine.
3.7.1 General Aspects and History.
3.7.2 Localization Within the Central Nervous System.
3.7.3 Biosynthesis and Degradation.
3.7.4 Receptors and Signal Transduction.
3.7.5 Biological Effects.
3.7.6 Neurological Disorders and Neurodegenerative Diseases.
3.8 Serotonin (5-Hydroxytryptamine).
3.8.1 General Aspects and History.
3.8.2 Localization Within the Central Nervous System.
3.8.3 Biosynthesis and Degradation.
3.8.4 Receptors and Signal Transduction.
3.8.5 Biological Effects.
3.8.6 Neurological Disorders and Neurodegenerative Diseases.
4 Neuromodulators.
4.1 Adrenocorticotropic Hormone.
4.1.1 General Aspects and History.
4.1.2 Localization Within the Central Nervous System.
4.1.3 Biosynthesis and Degradation.
4.1.4 Receptors and Signal Transduction.
4.1.5 Biological Effects.
4.1.6 Neurological Disorders and Neurodegenerative Diseases.
4.2 Anandamide (Endocannabinoids).
4.2.1 General Aspects and History.
4.2.2 Localization Within the Central Nervous System.
4.2.3 Biosynthesis and Degradation.
4.2.4 Receptors and Signal Transduction.
4.2.5 Biological Effects.
4.2.6 Neurological Disorders and Neurodegenerative Diseases.
4.3 Angiotensin.
4.3.1 General Aspects and History.
4.3.2 Localization Within the Central Nervous System.
4.3.3 Biosynthesis and Degradation.
4.3.4 Receptors and Signal Transduction.
4.3.5 Biological Effects.
4.3.6 Neurological Disorders and Neurodegenerative Diseases.
4.4 Atrial Natriuretic Factor.
4.4.1 General Aspects and History.
4.4.2 Localization Within the Central Nervous System.
4.4.3 Biosynthesis and Degradation.
4.4.4 Receptors and Signal Transduction.
4.4.5 Biological Effects.
4.4.6 Neurological Disorders and Neurodegenerative Diseases.
4.5 Bombesin and Related Neuropeptides.
4.5.1 General Aspects and History.
4.5.2 Localization Within the Central Nervous System.
4.5.3 Biosynthesis and Degradation.
4.5.4 Receptors and Signal Transduction.
4.5.5 Biological Effects.
4.6 Calcitonin and Calcitonin Gene-related Protein.
4.6.1 General Aspects and History.
4.6.2 Localization Within the Central Nervous System.
4.6.3 Biosynthesis and Degradation.
4.6.4 Receptors and Signal Transduction.
4.6.5 Biological Effects.
4.6.6 Neurological Disorders and Neurodegenerative Diseases.
4.7 Cholecystokinin.
4.7.1 General Aspects and History.
4.7.2 Localization Within the Central Nervous System.
4.7.3 Biosynthesis and Degradation.
4.7.4 Receptors and Signal Transduction.
4.7.5 Biological Effects.
4.7.6 Neurological Disorders and Neurodegenerative Diseases.
4.8 Corticotropin-releasing Factor.
4.8.1 General Aspects and History.
4.8.2 Localization Within the Central Nervous System.
4.8.3 Biosynthesis and Degradation.
4.8.4 Receptors and Signal Transduction.
4.8.5 Biological Effects.
4.8.6 Neurological Disorders and Neurodegenerative Diseases.
4.9 Dynorphin.
4.9.1 General Aspects and History.
4.9.2 Localization Within the Central Nervous System.
4.9.3 Biosynthesis and Degradation.
4.9.4 Receptors and Signal Transduction.
4.9.5 Biological Effects.
4.9.6 Neurological Disorders and Neurodegenerative Diseases.
4.10 Eicosanoids and Arachidonic Acid.
4.10.1 General and History Aspects.
4.10.2 Biosynthesis and Degradation.
4.10.3 Receptors and Signal Transduction.
4.10.4 Biological Effects.
4.10.5 Neurological Disorders and Neurodegenerative Diseases.
4.11 Endorphin.
4.11.1 General Aspects and History.
4.11.2 Localization Within the Central Nervous System.
4.11.3 Biosynthesis and Degradation.
4.11.4 Biological Effects.
4.11.5 Neurological Disorders and Neurodegenerative Diseases.
4.12 Enkephalin.
4.12.1 General Aspects and History.
4.12.2 Localization Within the Central Nervous System.
4.12.3 Biosynthesis and Degradation.
4.12.4 Receptors and Signal Transduction.
4.12.5 Biological Effects.
4.12.6 Neurological Disorders and Neurodegenerative Diseases.
4.13 Fibroblast Growth Factors.
4.13.1 General Aspects and History.
4.13.2 Localization Within the Central Nervous System.
4.13.3 Biosynthesis and Degradation.
4.13.4 Receptors and Signal Transduction.
4.13.5 Biological Effects.
4.13.6 Neurological Disorders and Neurodegenerative Diseases.
4.14 Galanin.
4.14.1 General Aspects and History.
4.14.2 Localization Within the Central Nervous System.
4.14.3 Biosynthesis and Degradation.
4.14.4 Receptors and Signal Transduction.
4.14.5 Biological Effects.
4.14.6 Neurological Disorders and Neurodegenerative Diseases.
4.15 Ghrelin.
4.15.1 General Aspects and History.
4.15.2 Localization Within the Central Nervous System.
4.15.3 Biosynthesis and Degradation.
4.15.4 Receptors and Signal Transduction.
4.15.5 Biological Effects.
4.15.6 Neurological Disorders and Neurodegenerative Diseases.
4.16 Gonadotropin-releasing Hormone.
4.16.1 General Aspects and History.
4.16.2 Localization Within the Central Nervous System.
4.16.3 Biosynthesis and Degradation.
4.16.4 Receptors and Signal Transduction.
4.16.5 Biological Effects.
4.16.6 Neurological Disorders and Neurodegenerative Diseases.
4.17 Growth Hormone-releasing Hormone.
4.17.1 General Aspects and History.
4.17.2 Localization Within the Central Nervous System.
4.17.3 Biosynthesis and Degradation.
4.17.4 Receptors and Signal Transduction.
4.17.5 Biological Effects.
4.17.6 Neurological Disorders and Neurodegenerative Diseases.
4.18 Hypocretin (Orexin).
4.18.1 General Aspects and History.
4.18.2 Localization Within the Central Nervous System.
4.18.3 Biosynthesis and Degradation.
4.18.4 Receptors and Signal Transduction.
4.18.5 Biological Effects.
4.18.6 Neurological Disorders and Neurodegenerative Diseases.
4.19 Interleukin.
4.19.1 General Aspects.
4.19.2 Localization Within the Central Nervous System.
4.19.3 Biosynthesis and Degradation.
4.19.4 Receptors and Signal Transduction.
4.19.5 Biological Effects.
4.19.6 Neurological Disorders and Neurodegenerative Diseases.
4.20 Melanin-concentrating Hormone.
4.20.1 General Aspects and History.
4.20.2 Localization Within the Central Nervous System.
4.20.3 Biosynthesis and Degradation.
4.20.4 Receptors and Signal Transduction.
4.20.5 Biological Effects.
4.20.6 Neurological Disorders and Neurodegenerative Diseases.
4.21 Melanocyte-stimulating Hormone.
4.21.1 General Aspects.
4.21.2 Localization Within the Central Nervous System.
4.21.3 Biosynthesis and Degradation.
4.21.4 Receptors and Signal Transduction.
4.21.5 Biological Effects.
4.21.6 Neurological Disorders and Neurodegenerative Diseases.
4.22 Neuropeptide Y.
4.22.1 General Aspects and History.
4.22.2 Localization Within the Central Nervous System.
4.22.3 Biosynthesis and Degradation.
4.22.4 Receptors and Signal Transduction.
4.22.5 Biological Effects.
4.22.6 Neurological Disorders and Neurodegenerative Diseases.
4.23 Neurotensin.
4.23.1 General Aspects and History.
4.23.2 Localization Within the Central Nervous System.
4.23.3 Biosynthesis and Degradation.
4.23.4 Receptors and Signal Transduction.
4.23.5 Biological Effects.
4.23.6 Neurological Disorders and Neurodegenerative Diseases.
4.24 Neurotrophins.
4.24.1 General Aspects and History.
4.24.2 Localization Within the Central Nervous System.
4.24.3 Biosynthesis and Degradation.
4.24.4 Receptors and Signal Transduction.
4.24.5 Biological Effects.
4.24.6 Neurological Disorders and Neurodegenerative Diseases.
4.25 Nitric Oxide and Carbon Monoxide.
4.25.1 General Aspects and History.
4.25.2 Localization Within the Central Nervous System.
4.25.3 Biosynthesis and Degradation.
4.25.4 Receptors and Signal Transduction.
4.25.5 Biological Functions.
4.25.6 Neurological Disorders and Neurodegenerative Diseases.
4.26 Nociceptin (Orphanin FQ).
4.26.1 General Aspects and History.
4.26.2 Localization Within the Central Nervous System.
4.26.3 Biosynthesis and Degradation.
4.26.4 Receptors and Signal Transduction.
4.26.5 Biological Effects.
4.26.6 Neurological Disorders and Neurodegenerative Diseases.
4.27 Pituitary Adenylate Cyclase-activating Polypeptide.
4.27.1 General Aspects and History.
4.27.2 Localization Within the Central Nervous System.
4.27.3 Biosynthesis and Degradation.
4.27.4 Receptors and Signal Transduction.
4.27.5 Biological Effects.
4.27.6 Neurological Disorders and Neurodegenerative Diseases.
4.28 Proopiomelanocortin.
4.28.1 General Aspects and History.
4.28.2 Localization Within the Central Nervous System.
4.28.3 Biosynthesis and Degradation.
4.28.4 Receptors and Signal Transduction.
4.28.5 Biological Effects.
4.29 Purines.
4.29.1 General Aspects.
4.29.2 Biosynthesis and Degradation.
4.29.3 Receptors and Signal Transduction.
4.29.4 Biological Effects.
4.29.5 Neurological Disorders and Neurodegenerative Diseases.
4.30 Somatostatin.
4.30.1 General Aspects and History.
4.30.2 Localization Within the Central Nervous System.
4.30.3 Biosynthesis and Degradation.
4.30.4 Receptors and Signal Transduction.
4.30.5 Biological Effects.
4.30.6 Neurological Disorders and Neurodegenerative Diseases.
4.31 Substance P and Tachykinins.
4.31.1 General Aspects and History.
4.31.2 Localization Within the Central Nervous System.
4.31.3 Biosynthesis and Degradation.
4.31.4 Receptors and Signal Transduction.
4.31.5 Biological Effects.
4.31.6 Neurological Disorders and Neurodegenerative Diseases.
4.32 Thyrotropin-releasing Hormone.
4.32.1 General Aspects and History.
4.32.2 Localization Within the Central Nervous System.
4.32.3 Biosynthesis and Degradation.
4.32.4 Receptors and Signal Transduction.
4.32.5 Biological Effects.
4.32.6 Neurological Disorders and Neurodegenerative Diseases.
4.33 The Tyr-MIF-1 Family.
4.34 Vasoactive Intestinal Polypeptide.
4.34.1 General Aspects and History.
4.34.2 Localization Within the Central Nervous System.
4.34.3 Biosynthesis and Degradation.
4.34.4 Receptors and Signal Transduction.
4.34.5 Biological Effects.
4.34.6 Neurological Disorders and Neurodegenerative Diseases.
4.35 Vasopressin and Oxytocin.
4.35.1 General Aspects and History.
4.35.2 Localization Within the Central Nervous System.
4.35.3 Biosynthesis and Degradation.
4.35.4 Receptors and Signal Transduction.
4.35.5 Biological Effects.
4.35.6 Neurological Disorders and Neurodegenerative Diseases.
4.36 Deorphanized Neuropeptides.
4.36.1 Apelin.
4.36.2 Kisspeptin/Metastin.
4.36.3 Opiod-modulating Peptides (NPFF and NPAF).
A Appendix.
A1 Amino Acids.
A2 Nucleotides.
A3 Abbreviations for Neurotransmitters and Neuromodulators.
A4 Miscellaneous Abbreviations (Enzymes and Transporters).
Subject Index. |
|
Summary: |
A complete update of the highly acclaimed handbook with data on all neurotransmitters and the majority of neuromodulators. The coverage is now even more comprehensive, with 15% more entries on neuropeptides, "classic" neurotransmitters and related substances in a clear, alphabetical format. The methodological section has been expanded by 50% and now includes color figures, plus new chapters on genomics, proteomics, databases, microarrays, MALDI-TOF, neutrophins, FGF, endocannabinoids and neuroimaging. The text provides clearly structured information on the biosynthesis and degradation, localization, receptors, signal transduction pathways, and biological effects in the central nervous system, with all substances uniformly treated for an easy comparison of data. Furthermore, introductory chapters on receptors, transporters, and the blood-brain barrier make this an indispensable tool for researchers, teachers, and advanced students, as well as a must-have for every neuroscientist. |
|
Author |
Oliver von Bohlen und Halbach gained his PhD in biology at the University of Constance, Germany. He carried out his postdoctoral training at the Medical Faculty, Charité of the Humboldt-University in Berlin (Director Professor U. Heinemann). Since 2001 he is postdoctoral fellow at the Interdisciplinary Center for Neurosciences (Director Professor K. Unsicker) at the Medical Faculty of the University of Heidelberg, Germany.
Rolf Dermietzel obtained his MD in 1970 at the Medical School Essen, Germany, where he continued his training, being appointed as Associate Professor 1976. In 1984 he started a research fellowship at the California Institute of Technology, Pasadena (supervisor Dr. J.-P. Revel) followed by a position as Visiting Professor at the Albert-Einstein College of Medicine, New York, in 1988. One year later he became Chairman of the Institute of Anatomy at the University of Regensburg, Germany, and in 1998 Chairman of the Institute of Anatomy at the University of Bochum, Germany. |
|
Ordering: |
Order Online - visit http://www.researchandmarkets.com/reports/349360
Order by Fax - using the order form below
Order By Post - print the order form below and send to
|
|
Research and Markets,
Guinness Centre,
Taylors Lane,
Dublin 8,
Ireland.
|
|
|
 |
Page 1 of 2
Printed 16/02/2012 03:28:17 |
|
Fax Order Form
To place an order via fax simply print this form, fill in the information below and
fax the completed form to
646-607-1907 (from USA) or +353 1 6849977 (from Rest of World). If you have any questions please email help@researchandmarkets.net
Order information
Please verify that the product information is correct and select the format you require.
|
|
|
|
Product Name: |
Neurotransmitters and Neuromodulators: Handbook of Receptors and Biological Effects, 2nd Edition
|
|
Web Address: |
http://www.researchandmarkets.com/reports/349360
|
|
Office Code: |
|
OC8IHINLSNNSS
|
Report formats
Please enter the quantity of the report format you require.
|
|
Format
|
Quantity
|
Price
|
|
Hard Copy
|
|
€149.00 + EUR€ 25.00 Shipping/Handling *
|
* Shipping/Handling is only charged once per order.
Contact information
Please enter all the information below in BLOCK CAPITALS.
|
|
|
First Name: |
Last Name: |
|
Email Address: |
|
|
Job Title: |
|
|
Organisation: |
|
|
Address: |
|
|
City: |
|
|
Postal/Zip Code: |
|
|
Country: |
|
|
Phone Number: |
|
|
Fax Number: |
|
|
Please fax this form to:
(646) 607-1907 or (646) 964-6609 (from USA)
+353-1-481-1716 or +353-1-653-1571 (from Rest of World)
|
|
Page 2 of 2
Printed 16/02/2012 03:28:17
|
|
Payment information
Please indicate the payment method you would like to use by selecting the appropriate
box.
|
|
|
|
|
American Express
|
|
|
Diners Club
|
|
|
Master Card
|
|
|
Visa
|
|
|
|
|
|
|
Cardholder's Name: |
|
|
|
|
Cardholder's Signature: |
|
|
|
|
Expiry Date: |
/ |
|
|
|
Card Number: |
|
|
|
|
CVV Security Code: |
|
|
|
|
Issue Date: |
/ (Diners
Club only)
|
|
|
|
|
|
|
Please post the check, accompanied by this form, to:
Research and Markets,
Guinness Centre,
Taylors Lane,
Dublin 8,
Ireland.
|
|
|
|
|
|
|
Please transfer funds to:
|
|
|
Account number: |
83313083 |
|
Sort code: |
98-53-30 |
|
Swift code: |
ULSBIE2D |
|
IBAN number: |
IE78ULSB98533083313083 |
|
Bank Address: |
Ulster Bank,
27-35 Main St,
Blackrock,
Co. Dublin,
Ireland. |
|
|
|
If you have a Marketing Code please enter it below:
|
|
|
Marketing Code: |
|
|
Please note that by ordering from Research and Markets you are agreeing to our Terms and Conditions at http://www.researchandmarkets.com/info/terms.asp
|
|
Please fax this form to:
(646) 607-1907 or (646) 964-6609 (from USA)
+353-1-481-1716 or +353-1-653-1571 (from Rest of World)
|
|
|
|
|
|
