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Advanced Life Sciences Cethromycin - Phase III Success Should Allow Me-too Market Entry and Above-consensus Growth
Datamonitor, Sep 2006, Pages: 17


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Traditionally, the treatment of respiratory infections has largely involved antibiotics from the macrolide class. Advanced Life Sciences cethromycin, along with Sanofi-Aventis Ketek, is a ketolide, a second-generation class of macrolides with activity against bacterial strains resistant to macrolides. Data from two Phase III trials in community-acquired pneumonia are expected in early 2007.

Scope of this title:
- Analyzes the potential for FDA approval and the market outlook for Advanced Life Sciences cethromycin
- We interviewed six infectious disease specialists and high-prescribing primary care physicians in the course of research

Highlights of this title:
- While there is some risk, dosing improvements over previous failed trials give cethromycin a good chance of yielding positive results in ongoing Phase III trials.
- We expect slow, steady erosion in market share of the macrolide class by the ketolides, driven by concerns over resistant strains of pathogens, but tempered by the established position of Pfizers leading macrolide, Zithromax, and the price discounts offered by its generic form.
- Recent concern over liver toxicity associated with Sanofi-Aventis Ketek, is likely to make physicians wary of cethromycin as well before its side effect profile is better known.

Reasons to order your copy:
- Understand the commercial potential for Advanced Life Sciences cethromycin, through in-depth analysis based on interviews with leading experts
- Anticipate likely changes in the future market dynamics for antibacterial agents if cethromycin were to be approved




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