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Biopharmaceutical Developments--An Emerging Technology Analysis (Technical Insights)
Frost & Sullivan, June 2005
Advances in Biotechnology Cause an Overhaul of Processes in the Pharmaceuticals Industry
Scientific developments in biotechnology have radically changed the global pharmaceuticals industry, since biopharmaceuticals can be tailored for specific medical problems in different individuals. With biotechnology, any drug can be genetically modified using cell fusion or deoxyribonucleic acid (DNA)-recombinant technologies to alter specificities for individual diseases. Some distinct advantages of biotechnology include fewer side effects and more potent effect on target cells. Pharmaceutical biotechnology is being developed further to fight cancer, viral infections, diabetes, and hepatitis as well as for developing safer and more effective antibiotics, insulins, interferons, estrogens, and human growth hormones.
This Technical Insights study provides an overview of the advances made by emerging technologies in biopharmaceuticals. The study includes detailed analyses of monoclonal antibodies, hormones and enzymes, cytokines and peptide therapeutics, vaccines and antigens, along with tissue engineering. It also provides technology challenges, market drivers and restraints as well as assesses innovations and opportunities. This research service enables companies to align their positioning strategies to benefit from these technologies.
Intense Research and Development Efforts Create a New Class of Biopharmaceuticals
Research organizations have invested vast amounts of resources in innovations in biotechnologies, which has resulted in the commercialization of new classes of biopharmaceuticals that find application in both disease therapy and prevention. Recently, biopharmaceuticals witnessed significant innovations and a robust pipeline of new biotherapeutics indicates strong growth for the biopharmaceutical industry in the short to medium term. Improvements in biotechnologies and sustained successes in the monoclonal antibody segment have enabled scientists to introduce novel categories of biopharmaceuticals that address fresh markets and target new diseases. In the future, the biopharmaceutical industry is likely to increasingly focus on products and, more particularly, on the diverse potential of monoclonal antibody products, says the analyst of this research service. Although new technologies are expected to continue to emerge, the spectrum of supportive technologies currently available is now permitting a growing pipeline of novel therapeutics. Biopharmaceutical drugs have already gained approval for use in oncology and inflammatory diseases and are gradually expected to permeate other areas of medical practice.
Advances in Gene Therapy and Genetic Engineering Present Tremendous Opportunities for Biopharmaceuticals
The mapping of the human genome has uncovered numerous new potential disease targets. Gene therapy involves the insertion of genetic materials into cells in order to repair or replace defective genes and to make the target cells more susceptible to treatment. An understanding of genomics and proteomics, along with biotechnology, has greatly spurred growth of biopharmaceutical technologies, notes the analyst. The ability to identify the exact genetic sequences to control the production of specific proteins has introduced many biopharmaceuticals for almost all applications. Biopharmaceuticals’ greatest potential lies in gene therapy and genetic engineering, which have been revolutionizing medicine with their ability to mass produce safe and more effective versions of proteins and enzymes created naturally by the human body.
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