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Advances in Medical Device Technology for Cardiovascular Applications (Technical Insights)
Frost & Sullivan, March 2005
Higher Incidence of Cardiovascular Diseases Sees Advances in Medical Devices for Cardiovascular Applications
The growing use of tobacco combined with poor nutritional habits and unhealthy lifestyles are contributing to an increase in incidence of cardiovascular diseases in the developed world. Remedies for conditions such as congestive heart failure (CHF) and atrial fibrillation (AF) are currently very limited and there is greater emphasis on finding treatments that are more successful. While significant advancements are being observed in the fields of interventional cardiology and minimally invasive surgery, pacemakers, coronary stents, implantable cardiac defibrillators, and angioplasty products are dominating the world market for cardiovascular products. Of these, the United States market is seeing the most notable innovations and developments.
This Technical Insights research service studies advances in cardiovascular medical device technologies. It provides information on organizations, companies, universities, research institutions, and government labs involved in R&D, along with their contact details. A summary of key patents is likely to give an insight into notable activities, technology trends, and major participants involved in the development and application of these technologies.
Development of Stent Technology Draws Greater Focu
Currently, some predominant technological advancements are focused on the development of stent technology. Drug-eluting stents have been highly successful and have prevented complications such as restenosis and thrombus - conditions that are associated with the use of bare metal stents. With the assurance of extremely low restenosis rates, many physicians estimate that up to one-third of surgical interventions (coronary artery bypass grafting procedures) can be avoided with the use of drug eluting stents. Also, as technology improves, physicians can better treat patients who are deemed unfit for surgery or angioplasty. Bio-absorbable stents, along with stents coated with bioengineered surfaces are, are expected to dominate the market for interventional cardiology. The opportunity to treat vulnerable plaque could add further expand the coronary stent market.
Cardiac rhythm management is a high-technology application, and advancements in this field are related to the development of easily implantable devices, that have greater longevity and better diagnostic and therapeutic capabilities. These devices are being modified to treat various comorbid conditions such as atrial fibrillation associated with heart failure. The current focus of development is on reaching lower defibrillation thresholds, which is likely to lead to conservation of energy and subsequently, enhance generator life, says the analyst of this research service. Miniaturization is also being pursued actively, with efforts aimed at reducing the generator size and volume.
Increase In Elderly Population Stimulating Demand for Cardiovascular Medical device
The majority of implants in the recent past have been developed for patients who are more than 50 years old. Globally, an aging population and their increasing need for healthcare services have created a huge demand for products that treat cardiovascular illnesses. Consequently, this stimulates the demand for cardiovascular medical devices and this growing population is expected to be a powerful driver for the advancement of medical devices for cardiovascular applications.
The highly competitive nature of the cardiac devices market has forced manufacturers to consolidate their resources through mergers and alliances. This has increased the dominance of larger companies and made it more difficult for the smaller participants to compete, says the analyst. There may be further consolidation in the future and the bigger companies with wider product mixes and more polished distribution channels are likely to enjoy better equity with the medical fraternity.
1. Executive Summary
1. Introduction
1. Introduction to Cardiovascular Diseases
2. Overview of Cardiovascular Medical Device Industry
2. Scope & Methodology
1. Scope and Segmentation of the Research Service
2. Methodology
2. Medical Devices to Treat Heart Failure
1. Technology Primer
1. Technology Primer for Electronic Therapies
2. Technology Primer for Surgical Therapies
2. Noteworthy Innovation at Key Companies Academic and Government-Related Institutions
1. Bipolar Lead to Offer Superior Handling and Stability for Left Ventricle Lead Placement--United States
2. Advances in Left Ventricular Assist Device to Treat Heart Failure--United States
3. Artificial Heart for End-Stage Heart Failure Patients--United States
4. Pacemaker Enabled With Home Monitoring of Heart Failure Patients--Germany
5. Shape Change Technology to Treat Mitral Valve Insufficiency--United States
6. CRT Device with Automated Fluid Status Monitoring
United States
7. Cardiac Support Device to Prevent Heart Remodeling--United States
8. Circulatory Assist Device for End-Stage Heart Failure--United States
9. First FDA-Approved VAD for Children--United States
10. Delivery System for Cardiac Resynchronization Therapy--United States
11. Foldable Heart Valve Means Less Invasive Surgery--Canada
3. Influential Market Factors
1. Industry Trends
2. Important Clinical Trials in Congestive Heart Failure
3. Medical Devices to Treat Cardiac Arrhythmias
1. Technology Primer
1. Technology Primer for Electronic and Ablation Therapies
2. Technology Primer for Surgical Procedures
2. Noteworthy Innovation at Key Companies Academic and Government-related Institutions
1. Laser-Based Ablation System To Treat Atrial Fibrillation--United States
2. Internal Cardioversion Catheter Combats Atrial Fibrillation-- United States
3. Hi-Intensity Focused Ultrasound for Simple and Reproducible Maze Procedure--United States
4. Minimally Invasive Device to Access Pericardial Space--United States
5. Noncontact Catheter System Maps Cardiac Arrhythmias--United States
6. Cryoablation Technique to Cure Complex Arrhythmias--United States
7. Duke Researchers Develop Novel Cardiac Telemetry System for Atrial Fibrillation--United States
8. Thinnest ICD Lead for Enhanced Cardiac Care--United States
9. Freezing Balloon to Treat Atrial Fibrillation--United States
10. Defibrillator Equipped With Wireless Data Transfer Technology--Netherlands
11. Pacing Device to Prevent AF In CHF Patients--Italy
3. Influential Market Factors
1. Industry Trends
2. Important Clinical Trials in Cardiac Rhythm Disorders
4. Medical Devices to Treat Coronary Artery Disease
1. Technology Primer
1. Technology Primer for Minimally Invasive Surgery
2. Technology Primer for Surgical Procedures
2. Noteworthy Innovation at Key Companies
Academic and Government-Related Institutions
1. Stent with Bio-Engineered Surface Combats Restenosis--Netherlands
2. A New Guidewire to Help Navigate Occluded Coronary Arteries--United States
3. Novel Distal Embolic Protection System--United States
4. Innovative Pressure Sensing Guidewire--Sweden
5. Enhanced External Counterpulsation for Myocardial Infarction--United Kingdom
6. Revitalize Ischemic Cells with Aqueous Oxygen--United States
7. Cobalt Chromium Stent to Treat CAD in Small Vessels--United States
8. Bifurcated Drug-Eluting Stent System Shows Strong Potential--United States
9. Proximal Embolic Protection System to Prevent Distal Embolization--United States
10. Unique Remote Catheterization System for Percutaneous Coronary Intervention--Israel
11. Explore Therapeutic Acoustic Energy to Treat Vascular Occlusive Diseases--United States
12. Endovascular Temperature Therapy to Treat Acute Ischemic and Inflammatory Disorders--United States
13. Ceramide-Coating Technology to Prevent Restenosis--United States
14. Absorbable Metal Stent to Enhance Natural Vessel Remodelling--Germany
3. Influential Market Factors
1. Industry Trends
2. Important Clinical Trials in Coronary Artery Disease
5. Technology Adoption Factor Analysis and Commercial Landscape
1. Technology Analysis
1. Technology Accelerators
2. Technology Roadblocks
3. Regulatory Trends
2. Venture Capital Landscape
1. Overview
2. Venture Capital Space
3. Mergers and Acquisitions
1. Overview
2. Important Mergers and Acquisitions in the Industry
6. Frost & Sullivan 2005 Science & Technology Awards
1. Technology Innovation Award
1. Award Description
2. Award Recipient
2. Technology Leadership Award
1. Award Description
2. Award Recipient
3. Product Leadership Award
1. Award Description
2. Award Recipient
7. Database of Key Industry Participants
Selected Patents & Glossary
1. Database of Key Industry Participants
1. Companies and Organizations
2. Universities and Academia
2. Selected Patents & Glossary
1. Important Patents Related to Devices for Treating CHF
2. Important Patents Related to Devices for Treating Rhythm Disorders
3. Important Patents Related to Devices for Treating CAD
8. Critical Reference Tables
1. Decision Support Database Tables
1. Population Aged 65 Years and Above (1999 -2006)
2. Hypertension Prevalence (1999-2006)
3. Incidence of Myocardial Infarction (1999-2006)
4. Coronary Heart Disease Mortality (1999-2006)
5. Number of Heart Transplants (1999-2003)
6. Number of Cardiologist (1999-2006)
7. Prevalence of Diabetes (1999-2006)
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