The world's number 1 dermatology information resource
Universally respected, Rook's Textbook of Dermatology is the most comprehensive, definitive and best-illustrated reference work for dermatologists of all levels worldwide and has been at the forefront of international dermatology publishing since first appearing in 1968.
The Ninth Edition has been radically re-engineered to match the modern day challenges faced by dermatologists. Once again it has been published as a combined digital and print resource, but with a new online platform enabling easier and faster navigation.
A common structure to describe and discuss each disorder has been adopted throughout, whilst maintaining the depth of information for which Rook is renowned. A high priority has been placed on the ease of extracting key information quickly: diagnostic algorithms and management ladders help the reader choose appropriate treatment strategies. More images than ever – over 5000 in total – aid diagnosis by displaying variations in disease manifestations according to body location, skin type and severity. The section on aesthetic dermatology has been greatly expanded with more coverage of procedures in this rapidly developing field. More comprehensive than ever, with more images, more disorders covered and faster, more dynamic and wider digital search functionality. It is an essential resource for the modern day dermatologist, whether experienced or at the beginning of a career in dermatology.
Table of Contents
List of Associate Editors x
List of Contributors xi
Preface to the Ninth Edition xxi
Preface to the First Edition xxii
Volume 1
Part 1 Foundations of Dermatology
1 History of Dermatology 1.1
Nick J. Levell
2 Structure and Function of the Skin 2.1
John A. McGrath and Jouni Uitto
3 Histopathology of the Skin: General Principles 3.1
Eduardo Calonje with a contribution from Balbir S. Bhogal (Immunofluorescence techniques)
4 Diagnosis of Skin Disease 4.1
Ian H. Coulson Emma C. Benton and Stephanie Ogden
5 Epidemiology of Skin Disease 5.1
Hywel C. Williams
6 Health Economics and Skin Disease 6.1
Matthias Augustin and Magdalene Krensel
7 Genetics and the Skin 7.1
John A. McGrath
8 Inflammation Immunology and Allergy 8.1
Martin Steinhoff
9 Photobiology 9.1
Antony R. Young
10 Cutaneous Response to Injury and Wound Healing 10.1
Edel A. O’Toole
11 Psychological and Social Impact of Long-term Dermatological Conditions 11.1
Christine Bundy and Lis Cordingley
12 Adverse Immunological Reactions to Drugs 12.1
Michael R. Ardern‐Jones
13 Topical Drug Delivery 13.1
Richard H. Guy
14 Clinical Pharmacology 14.1
Catherine H. Smith
Part 2 Management
15 Principles of Holistic Management of Skin Disease 15.1
Sam Gibbs
16 Principles of Measurement and Assessment in Dermatology 16.1
Andrew Y. Finlay
17 Principles of Evidence‐based Dermatology 17.1
Michael Bigby and Hywel C. Williams
18 Principles of Topical Therapy 18.1
John Berth‐Jones
19 Principles of Systemic Therapy 19.1
Michael J. Tidman and Catherine H. Smith
20 Principles of Skin Surgery 20.1
S. Walayat Hussain Richard J. Motley and Timothy S. Wang
21 Principles of Phototherapy 21.1
Kevin McKenna and Sally Ibbotson
22 Principles of Photodynamic Therapy 22.1
Sally Ibbotson and Kevin McKenna
23 Principles of Cutaneous Laser Therapy 23.1
Vishal Madan and Richard J. Barlow
24 Principles of Radiotherapy 24.1
Charles G. Kelly and John Frew
Part 3 Infections and Infestations
25 Viral Infections 25.1
Jane C. Sterling
26 Bacterial Infections 26.1
Roderick J. Hay and Rachael Morris‐Jones
27 Mycobacterial Infections 27.1
Victoria M. Yates and Stephen L. Walker
28 Leprosy 28.1
Diana N. J. Lockwood
Introduction to Chapters 29 and 30: Global Overview of Sexually Transmitted Infections 29.1
George R. Kinghorn and Rasha Omer
29 Syphilis and Congenital Syphilis 29.3
George R. Kinghorn and Rasha Omer
30 Other Sexually Transmitted Bacterial Diseases 30.1
George R. Kinghorn Aparna Briggs and Nadi K. Gupta
31 HIV and the Skin 31.1
Christopher B. Bunker and Vincent Piguet
32 Fungal Infections 32.1
Roderick J. Hay and H. Ruth Ashbee
33 Parasitic Diseases 33.1
Christopher Downing and Stephen Tyring
34 Arthropods 34.1
Gentiane Monsel Pascal Delaunay and Olivier Chosidow
Index
Volume 2
Part 4 Inflammatory Dermatoses
35 Psoriasis and Related Disorders 35.1
A. David Burden and Brian Kirby
36 Pityriasis Rubra Pilaris 36.1
Anthony C. Chu
37 Lichen Planus and Lichenoid Disorders 37.1
Vincent Piguet Stephen M. Breathnach and Laurence Le Cleach
38 Graft‐versus‐host Disease 38.1
Tanya N. Basu
39 Eczematous Disorders 39.1
John R. Ingram
40 Seborrhoeic Dermatitis 40.1
Sarah Wakelin
41 Atopic Eczema 41.1
Michael R. Ardern‐Jones Carsten Flohr Nick J. Reynolds and Colin A. Holden
42 Urticaria 42.1
Clive E. H. Grattan and Alexander M. Marsland
43 Recurrent Angio‐oedema without Weals 43.1
Clive E. H. Grattan and Marcus Maurer
44 Urticarial Vasculitis 44.1
Elena Borzova and Clive E. H. Grattan
45 Autoinflammatory Diseases Presenting in the Skin 45.1
Dan Lipsker Clive E. H. Grattan and Christopher R. Lovell
46 Mastocytosis 46.1
Clive E. H. Grattan and Deepti H. Radia
47 Reactive Inflammatory Erythemas 47.1
Malcolm Rustin and Rino Cerio
48 Adamantiades–Behçet Disease 48.1
Christos C. Zouboulis
49 Neutrophilic Dermatoses 49.1
Anthony D. Ormerod and Philip J. Hampton
50 Immunobullous Diseases 50.1
Enno Schmidt and Richard Groves
51 Lupus Erythematosus 51.1
Mark Goodfield Jan Dutz and Collette McCourt
52 Antiphospholipid Syndrome 52.1
Mark Goodfield and Shyamal Wahie
53 Dermatomyositis 53.1
Patrick Gordon and Daniel Creamer
54 Mixed Connective Tissue Disease 54.1
Mark Goodfield
55 Dermatological Manifestations of Rheumatoid Disease 55.1
Mark Goodfield
56 Systemic Sclerosis 56.1
Catherine H. Orteu and Christopher P. Denton
57 Morphoea and Allied Scarring and Sclerosing Inflammatory Dermatoses 57.1
Catherine H. Orteu
Part 5 Metabolic and Nutritional Disorders Affecting the Skin
58 Cutaneous Amyloidoses 58.1
Stephan Schreml
59 Cutaneous Mucinoses 59.1
Franco Rongioletti
60 Cutaneous Porphyrias 60.1
Robert P. E. Sarkany
61 Calcification of the Skin and Subcutaneous Tissue 61.1
Johnny Bourke
62 Xanthomas and Abnormalities of Lipid Metabolism and Storage 62.1
Paul D. Flynn
63 Nutritional Disorders Affecting the Skin 63.1
Derek H. Chu Melinda V. Jen and Albert C. Yan
64 Skin Disorders in Diabetes Mellitus 64.1
Johnny Bourke
Part 6 Genetic Disorders Involving the Skin
65 Inherited Disorders of Cornification 65.1
Vinzenz Oji Dieter Metze and Heiko Traupe
66 Inherited Acantholytic Disorders 66.1
Mozheh Zamiri and Colin S. Munro
67 Ectodermal Dysplasias 67.1
Peter Itin
68 Inherited Hair Disorders 68.1
Eli Sprecher
69 Genetic Defects of Nails and Nail Growth 69.1
Adam Rubin and Amy S. Paller
70 Genetic Disorders of Pigmentation 70.1
Alain Taïeb Fanny Morice‐Picard and Khaled Ezzedine
71 Genetic Blistering Diseases 71.1
John A. McGrath
72 Genetic Disorders of Collagen Elastin and Dermal Matrix 72.1
Nigel Burrows
73 Disorders Affecting Cutaneous Vasculature 73.1
Anne Dompmartin Nicole Revencu Laurence M. Boon and Miikka Vikkula
74 Genetic Disorders of Adipose Tissue 74.1
George W. M. Millington
75 Congenital Naevi and Other Developmental Abnormalities Affecting the Skin 75.1
Veronica A. Kinsler and Neil J. Sebire
76 Chromosomal Disorders 76.1
Alan D. Irvine and Jemima E. Mellerio
77 Poikiloderma Syndromes 77.1
Alan D. Irvine and Jemima E. Mellerio
78 DNA Repair Disorders with Cutaneous Features 78.1
Hiva Fassihi
79 Syndromes with Premature Ageing 79.1
Alan D. Irvine and Jemima E. Mellerio
80 Hamartoneoplastic Syndromes 80.1
Alan D. Irvine and Jemima E. Mellerio
81 Inherited Metabolic Diseases 81.1
Andrew Morris
82 Inherited Immunodeficiency 82.1
Tim Niehues and Andrew R. Gennery
Part 7 Psychological Sensory and Neurological Disorders and the Skin
83 Pruritus Prurigo and Lichen Simplex 83.1
Sonja Ständer and Malcolm Greaves
84 Mucocutaneous Pain Syndromes 84.1
Joanna M. Zakrzewska and Anthony Bewley
85 Neurological Conditions Affecting the Skin 85.1
David J. Eedy
86 Psychodermatology and Psychocutaneous Disease 86.1
Anthony Bewley and Ruth E. Taylor
Index
Volume 3
Part 8 Skin Disorders Associated with Specific Cutaneous Structures
87 Acquired Disorders of Epidermal Keratinization 87.1
Anthony C. Chu and Fernanda Teixeira
88 Acquired Pigmentary Disorders 88.1
Nanja van Geel and Reinhart Speeckaert
89 Acquired Disorders of Hair 89.1
Andrew G. Messenger Rodney D. Sinclair Paul Farrant and David A. R. de Berker
90 Acne 90.1
Alison M. Layton E. Anne Eady and Christos C. Zouboulis
91 Rosacea 91.1
Frank C. Powell
92 Hidradenitis Suppurativa 92.1
Nemesha Desai Hessel H. van der Zee and Gregor B. E. Jemec
93 Other Acquired Disorders of the Pilosebaceous Unit 93.1
Roderick J. Hay Rachael Morris‐Jones and Gregor B. E. Jemec
94 Disorders of the Sweat Glands 94.1
Ian H. Coulson and Niall J. E. Wilson
95 Acquired Disorders of the Nails and Nail Unit 95.1
David A. R. de Berker Bertrand Richert and Robert Baran
96 Acquired Disorders of Dermal Connective Tissue 96.1
Christopher R. Lovell
97 Granulomatous Disorders of the Skin 97.1
Johnny Bourke
98 Sarcoidosis 98.1
Joaquim Marcoval and Juan Mañá
99 Panniculitis 99.1
Luis Requena
100 Other Acquired Disorders of Subcutaneous Fat 100.1
Amy Y.‐Y. Chen and Amit Garg
Part 9 Vascular Disorders Involving the Skin
101 Purpura 101.1
Tabi A. Leslie
102 Cutaneous Vasculitis 102.1
Nick J. Levell and Chetan Mukhtyar
103 Dermatoses Resulting from Disorders of the Veins and Arteries 103.1
Portia C. Goldsmith
104 Ulceration Resulting from Disorders of the Veins and Arteries 104.1
Jürg Hafner
105 Disorders of the Lymphatic Vessels 105.1
Peter S. Mortimer and Kristiana Gordon
106 Flushing and Blushing 106.1
Síona Ní Raghallaigh and Frank C. Powell
Part 10 Skin Disorders Associated with Specific Sites Sex and Age
107 Dermatoses of the Scalp 107.1
Paul Farrant Megan Mowbray and Rodney D. Sinclair
108 Dermatoses of the External Ear 108.1
Cameron Kennedy
109 Dermatoses of the Eye Eyelids and Eyebrows 109.1
Valerie P. J. Saw and Jonathan N. Leonard
110 Dermatoses of the Oral Cavity and Lips 110.1
Crispian Scully
111 Dermatoses of the Male Genitalia 111.1
Christopher B. Bunker and William M. Porter
112 Dermatoses of the Female Genitalia 112.1
Fiona Lewis
113 Dermatoses of Perineal and Perianal Skin 113.1
Eleanor Mallon
114 Cutaneous Complications of Stomas and Fistulae 114.1
Calum Lyon
115 Dermatoses of Pregnancy 115.1
Samantha Vaughan Jones
116 Dermatoses of the Neonate 116.1
David G. Paige
117 Dermatoses and Haemangiomas of Infancy 117.1
Elisabeth M. Higgins and Mary T. Glover
Index
Volume 4
Part 11 Skin Disorders Caused by External Agents
118 Benign Cutaneous Adverse Reactions to Drugs 118.1
Michael R. Ardern‐Jones and Haur Yueh Lee
119 Severe Cutaneous Adverse Reactions to Drugs 119.1
Sarah Walsh Haur Yueh Lee and Daniel Creamer
120 Cutaneous Side Effects of Chemotherapy and Radiotherapy 120.1
Louise Fearfield and Janakan Natkunarajah
121 Dermatoses Induced by Illicit Drugs 121.1
Daniel Creamer and Michael Gossop
122 Dermatological Manifestations of Metal Poisoning 122.1
Rabindranath Nambi
123 Mechanical Injury to the Skin 123.1
Saqib J. Bashir and Ai‐Lean Chew
124 Pressure Injury and Pressure Ulcers 124.1
Robyn Evans Carol Ott and Madhuri Reddy
125 Cutaneous Reactions to Cold and Heat 125.1
Saqib J. Bashir and Ai‐Lean Chew
126 Burns and Heat Injury 126.1
Marc G. Jeschke
127 Cutaneous Photosensitivity Diseases 127.1
Sally Ibbotson and Robert Dawe
128 Allergic Contact Dermatitis 128.1
Mark Wilkinson and David Orton
129 Irritant Contact Dermatitis 129.1
Jonathan M. L. White
130 Occupational Dermatology 130.1
Jonathan M. L. White
131 Stings and Bites 131.1
Stephen Tyring and Christopher Downing
Part 12 Neoplastic Proliferative and Infiltrative Disorders Affecting the Skin
132 Benign Melanocytic Proliferations and Melanocytic Naevi 132.1
Irene Stefanaki Christina Antoniou and Alexander Stratigos
133 Benign Keratinocytic Acanthomas and Proliferations 133.1
Vishal Madan and John T. Lear
134 Cutaneous Cysts 134.1
John T. Lear and Vishal Madan
135 Lymphocytic Infiltrates 135.1
Fiona Child and Sean J. Whittaker
136 Cutaneous Histiocytoses 136.1
Thai Hoa Tran Elena Pope and Sheila Weitzman
137 Soft‐tissue Tumours and Tumour‐like Conditions 137.1
Eduardo Calonje
138 Tumours of Skin Appendages 138.1
Eduardo Calonje
139 Kaposi Sarcoma 139.1
Kenneth Y. Tsai
140 Cutaneous Lymphomas 140.1
Sean J. Whittaker and Fiona Child
141 Basal Cell Carcinoma 141.1
Vishal Madan and John T. Lear
142 Squamous Cell Carcinoma and its Precursors 142.1
Girish Gupta Vishal Madan and John T. Lear
143 Melanoma 143.1
Melanoma Clinicopathology 143.2
Jean Jacques Grob and Caroline Gaudy‐Marqueste
Melanoma Surgery 143.23
Kelly B. Cha Timothy M. Johnson and Alison B. Durham
Systemic Treatment of Melanoma 143.28
Reinhard Dummer and Simone M. Goldinger
144 Dermoscopy of Melanoma and Naevi 144.1
Natalia Jaimes and Ashfaq A. Marghoob
145 Merkel Cell Carcinoma 145.1
Jürgen C. Becker David Schrama and Axel zur Hausen
146 Skin Cancer in the Immunocompromised Patient 146.1
Catherine A. Harwood Jane M. McGregor and Charlotte M. Proby
Part 13 Systemic Disease and the Skin
147 Cutaneous Markers of Internal Malignancy 147.1
Lennart Emtestam and Karin Sartorius
148 The Skin and Disorders of the Haematopoietic and Immune Systems 148.1
Robert Gniadecki
149 The Skin and Endocrine Disorders 149.1
Ralf Paus
150 The Skin and Disorders of the Heart 150.1
Sonja Molin and Thomas Ruzicka
151 The Skin and Disorders of the Respiratory System 151.1
Sonja Molin and Thomas Ruzicka
152 The Skin and Disorders of the Digestive System 152.1
Sonja Molin and Thomas Ruzicka
153 The Skin and Disorders of the Kidney and Urinary Tract 153.1
Sonja Molin and Thomas Ruzicka
154 The Skin and Disorders of the Musculoskeletal System 154.1
Christopher R. Lovell
Part 14 Aesthetic Dermatology
155 Skin Ageing 155.1
Dana L. Sachs Gary Fisher and John J. Voorhees
156 Cosmeceuticals 156.1
Eubee Koo Alexandra B. Kimball and Molly Wanner
157 Soft Tissue Augmentation (Fillers) 157.1
Berthold Rzany
158 Aesthetic Uses of Botulinum Toxins 158.1
Nicholas J. Lowe
159 Chemical Peels 159.1
Chee‐Leok Goh and Joyce Teng Ee Lim
160 Lasers and Energy‐based Devices 160.1
Nazanin Saedi and Christopher B. Zachary
Index
