U.S. Growth Factors Markets

Frost & Sullivan, February 2002

Medicinal Possibilities Hold Promise of Prosperous Market

Growth factor proteins are found naturally within the body and are essential
to the growth and repair of human tissue. Recent advances in genomic

technology have enabled scientists to identify the specific genes responsible
for their creation. This has allowed for the large-scale production of growth
factors, creating a market that holds tremendous promise.

This Frost & Sullivan analysis provides a comprehensive examination of the
U.S. growth factors markets. By identifying industry drivers and evaluating
emerging challenges, this study supplies your company with a resourceful
guide to market success.

Aging Population Fuels Need for More Effective, Less Invasive Therapies

One of the greatest challenges facing the healthcare providers who treat
America’s aging population is providing access to effective therapeutics that
stimulate repair in tissues and organ systems damaged by age and disease.
Currently, there are insufficient therapies that address the underlying loss of
tissue function inherent in degenerative disorders.

Alzheimer’s disease, malignancies, trauma, autoimmune disorders, and other

similar conditions create the need for more efficient and less invasive
therapies,” says the author. “It is expected that the increase in age-related

diseases will be the most crucial driver for the growth factors industry over
the next decade.

Development of New Delivery Methods Drive Industry Evolution

Growth factors resulted from the advent of human recombinant
technologies, where biotechnology successfully mimicked the necessary
regulatory proteins for the treatment of certain ailments. Thus, new
systems are also being developed for better delivery of growth factors.
As drug discovery continues to evolve, the number of proteins that will be
discovered, sequenced, and applied to treat human diseases will increase
exponentially,” states the analyst. “Innovative delivery systems will heighten

acceptance for the use of growth factors as viable and effective therapies well
into the future.”

This Frost & Sullivan study provides an in-depth analysis of the marketplace,

offering your company the inside information necessary to take advantage of
lucrative opportunities.

Additional Information

Market Participants
Amgen, Inc.
Aurogen, Inc.
Berlex Laboratories, Inc.
Biogen, Inc.
Biomira, Inc.
Boston Life Sciences, Inc.

CelMed
Chiron Corp.
Corvas International, Inc.
CuraGen Corp.
Curis, Inc.
Cytokine PharmaSciences, Inc.
Demegen, Inc.
Genentech, Inc.
Howmedica/Stryker Corp.
Human Genome Sciences, Inc.
Immunex Corp.
Interferon Sciences, Inc.
Johnson & Johnson/Ortho-McNeil
Ligand Pharmaceuticals, Inc.
Medtronic, Inc.
NeoTherapeutics, Inc.
Nobex Corp.
Receptron, Inc.
Regeneron Pharmaceuticals, Inc.

Regenesis
Roche Diagnostics Corp.
Schering-Plough Corp.
Scios, Inc.
Sigma-Aldrich Co.
Stryker Corp.
Sulzer Biologic, Inc.
SuperGen, Inc.

Theratechnologies

Wyeth Ayerst
ZymoGenetics, Inc.

Aerospace

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Biotech

Chemicals

Conferencing

Consumer

e-Business

Environment

Food

Healthcare

Internet Security

IT

Latin America

Medical Devices

Motors

Pharmaceuticals

Power

Sensors

Smart Cards

Technical Insights

Telecom Services

Transportation

Water

Wireless

1. Executive Summary
A. Executive Summary

1. Executive Summary

2. Total Market
A. Overview

1. Introduction

2. Challenges

3. Market Drivers

4. Market Restraints

5. Market Engineering Analysis
B. Forecasts and Trends

1. Revenue Forecasts

2. Demand Analysis

3. Pricing Trends
C. Frost & Sullivan Market Engineering Awards

1. Entrepreneurial Company Award

2. Market Penetration Award

3. Product Differentiation Innovation Award

4. Strategic Alliance Innovation Award

5. Technology Innovation Award

3. Blood Growth Factors Market
A. Blood Growth Factors - Overview

1. Introduction

2. Challenges

3. Market Drivers

4. Market Restraints

5. Market Engineering Analysis
B. Erythropoietins

1. Overview

2. Demand Analysis

3. Product Analysis
C. Colony Stimulating Growth Factors

1. Overview

2. Demand Analysis

3. Product Analysis
D. Interleukins (Cytokines)

1. Overview

2. Demand Analysis

3. Product Analysis
E. Interferons

1. Overview

2. Demand Analysis

3. Product Analysis
F. Blood Growth Factors - Forecasts and Trends

1. Revenue Forecasts

2. Revenue Forecast Assumptions

3. Market and Technology Trends

4. Pricing Trends
G. Blood Growth Factors - Competitive Analysis

1. Competitive Structure

2. Market Share Analysis
H. Blood Growth Factors - Strategic Recommendations

1. Strategic Recommendations for Market Challenge 1

2. Strategic Recommendations for Market Challenge 2

4. Tissue Growth Factors Market
A. Tissue Growth Factors - Overview

1. Introduction

2. Challenges

3. Market Drivers

4. Market Restraints

5. Market Engineering Analysis
B. Wound Healing Growth Factors

1. Overview

2. Demand Analysis

3. Product Analysis
C. Neurotrophic Growth Factors

1. Overview

2. Demand Analysis

3. Product Analysis
D. Musculoskeletal Tissue Growth Factors

1. Overview

2. Demand Analysis

3. Product Analysis
E. Tissue Growth Factors - Forecasts and Trends

1. Revenue Forecasts

2. Revenue Forecast Assumptions

3. Market and Technology Trends

4. Pricing Trends
F. Tissue Growth Factors - Competitive Analysis

1. Competitive Structure

2. Market Share Analysis
G. Tissue Growth Factors - Strategic Recommendations

1. Strategic Recommendations for Market Challenge 1

2. Strategic Recommendations for Market Challenge 2

3. Strategic Recommendations for Market Challenge 4

List Of Figures

Chapter 2

Growth Factors Market: Market Challenges Ranked in Order of Impact (U.S.), 2001-2008
Growth Factors Market: Market Drivers Ranked in Order of Impact (U.S.), 2001-2008
Growth Factors Market: Market Restraints Ranked in Order of Impact (U.S.), 2001-2008
Growth Factors Market: Total Revenue Forecasts (U.S.), 1998-2008
Growth Factors Market: Revenue Forecasts by Product Type (U.S.), 1998-2008
Growth Factors Market: Demand Analysis by Condition (U.S.), 1998-2008
Growth Factors Market: Pricing (U.S.), 2001

Chapter 3

Blood Growth Factors Market: Market Challenges Ranked in Order of Impact (U.S.), 2001-2008
Blood Growth Factors Market: Market Drivers Ranked in Order of Impact (U.S.), 2001-2008
Blood Growth Factors Market: Market Restraints Ranked in Order of Impact (U.S.), 2001-2008
Blood Growth Factors Market: Erythropoietin Demand Analysis (U.S.), 1998-2008
Blood Growth Factors Market: Colony Stimulating Growth Factors and Their Primary Functions (U.S.), 2001
Blood Growth Factors Market: Colony Stimulating Factors Demand Analysis (U.S.), 1998-2008
Blood Growth Factors Market: Interleukins and Their Primary Functions (U.S.), 2001
Blood Growth Factors Market: Interleukin Demand Analysis (U.S.), 1998-2008
Blood Growth Factors Market: Interferon Demand Analysis (U.S.), 1998-2008
Blood Growth Factors Market: Interferon Product Analysis (U.S.), 2001
Blood Growth Factors Market: Total Revenue Forecasts (U.S.), 1998-2008
Blood Growth Factors Market: Total Revenue Forecasts by Product Type (U.S.), 1998-2008
Blood Growth Factors Market: Pricing (U.S.), 2001
Blood Growth Factors Market: Competitive Structure (U.S.), 2001
Blood Growth Factors Market: Market Share Trends of Major Market Participants— Erythropoietins (U.S.), 2001-2002
Blood Growth Factors Market: Market Share Trends of Major Market Participants—Colony Stimulating Growth Factors (U.S.), 2001-2002
Blood Growth Factors Market: Market Share Trends of Major Market Participants— Interleukins (U.S.), 2001-2002
Blood Growth Factors Market: Market Share Trends of Major Market Participants— Interferons (U.S.), 2001-2002

Chapter 4

Tissue Growth Factors Market: Market Challenges Ranked in Order of Impact (U.S.), 2001-2008
Tissue Growth Factors Market: Market Drivers Ranked in Order of Impact (U.S.), 2001-2008
Tissue Growth Factors Market: Market Restraints Ranked in Order of Impact (U.S.), 2001-2008
Tissue Growth Factors Market: Demand Analysis by Condition (U.S.), 1998-2008
Tissue Growth Factors Market: Wound Growth Factors—Product Analysis (U.S.), 2001
Tissue Growth Factors Market: Neurotrophic Growth Factors—Demand Analysis by Condition (U.S.), 1998-2008
Tissue Growth Factors Market: Neurotrophic Growth Factors—Product Analysis (U.S.), 2001
Tissue Growth Factors Market: Musculoskeletal Growth Factors—Demand Analysis by Condition and by Procedure (U.S.), 1998-2008
Tissue Growth Factors Market: Musculoskeletal Growth Factors—Product Analysis (U.S.), 2001
Tissue Growth Factors Market: Total Revenue Forecasts (U.S.), 1998-2008
Tissue Growth Factors Market: Revenue Forecasts by Type of Growth Factor (U.S.), 1998-2008
Tissue Growth Factors Market: Pricing (U.S.), 2001
Tissue Growth Factors Market: Competitive Structure (U.S.), 2001
Tissue Growth Factors Market: Market Share Trends of Major Market Participants—Wound Growth Factors (U.S.), 2005-2006
Tissue Growth Factors Market: Market Share Trends of Major Market Participants—Neurotrophic Growth Factors (U.S.), 2005-2006
Tissue Growth Factors Market: Market Share Trends of Major Market Participants—Musculoskeletal Growth Factors (U.S.), 2001-2002

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