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U.S. Markets for Biomaterial Applications of Hyaluronic Acid (HA)
Frost & Sullivan, September 2004
Hyaluronic Acid-based Biomaterials Pervade the Healthcare Industry
Hyaluronic acid (HA)-based biomaterials have wide-ranging applications in the healthcare industry. The materials derived from HA are being used to relieve the pain of knee osteoarthritis, in cataract surgeries, in abdominal and pelvic surgeries, and as a dermal filler to erase facial wrinkles. Moreover, an aging population, several product innovations, and underserved end-user segments are creating a huge market for HA-based biomaterials. Some existing end users include rheumatologists, ophthalmologists, plastic and reconstructive surgeons, anti-adhesive wound care specialists, and gynecologists.
This Frost & Sullivan strategic analysis service provides an overview of and an outlook for the U.S. biomaterial applications of hyaluronic acid. The study is segmented into viscosupplementation products for osteoarthritis, viscoelastic products for ophthalmic applications, facial aesthetic implants, and post-surgical anti-adhesion barriers. It enables the development of growth strategies to enhance companies’ market shares and revenue.
HA-based Biomaterials Need a Dose of Innovation to Stay Ahead
Many market segments where HA-based biomaterials have become firmly entrenched are facing increasing reimbursement pressure from Medicare and other healthcare providers. An example is the lower reimbursements for physicians for cataract surgeries, who, in turn, want reduced prices for HA-based viscoelastics. Medicare is also cutting reimbursements of viscosupplementation procedures using HA-based material for knee osteoarthritis. These market segments have not seen significant recent innovation with HA-based biomaterials. The market also needs to fight price erosion by adding value to its products.
Some market participants are already planning to develop the next generation of viscosupplements as good carriers for drug delivery. Medical device manufacturers can also fund research to unravel the mechanism of viscosupplements. Once this is done, it will boost physician confidence leading to increased use of this procedure, says the analyst. Product manufacturers and marketers are also likely to ensure that their products maintain the value-to-price ratio in order to gain wide customer appeal.
Demand Expected to be Buoyed by Aging Baby Boomers
The number of people above 65 years is expected to more than double from 35 million in 2000 to 71 million in 2020 in the United States. People in this age group will be entering a stage where the incidence of osteoarthritis, cataract, and facial wrinkles increases. HA-based biomaterials have a significant role to play in the treatment of all these afflictions. Thus, the demand for HA-based biomaterials is expected to be spurred by the aging demographics.
Since the knee osteoarthritis patient population is expected to increase by 26 percent from 15 million in 2000 to 19 million in 2010, viscosupplements can expect an escalation in demand. Apart from a huge market for osteoarthritis medication, the post-surgical anti-adhesion barrier market also carries a huge potential. Internal adhesions after abdominal surgeries can cause problems, such as bowel obstruction and pain. Due to the critical nature of these complications, surgeons are demanding anti-adhesion barriers that perform consistently, notes the analyst. Adhesion lysis surgeries are performed more frequently on those above 65 years than on younger age groups.
1. Total Hyaluronic Acid-based Biomaterials Markets
- 1. Executive Summary and Overview
- - 1. Executive Summary
- - 2. Overview
- - 3. Major Participants in this Industry
- 2. Research Segmentation
- - 1. Segmentation by Product
- - 2. Segmentation by End User
- 3. Forecasts and Trends
- - 1. Market Drivers
- - - a. Osteoarthritis Viscosupplementation
- - - b. Ophthalmic Viscoelastic Applications
- - - c. Facial Aesthetics
- - - d. Post-surgical Anti-adhesion Barriers
- - 2. Market Challenges
- - - a. Osteoarthritis Viscosupplementation
- - - b. Ophthalmic Viscoelastic Applications
- - - c. Facial Aesthetics
- - - d. Post-surgical Anti-adhesion Barrier
- - 3. Revenue Forecasts
- 4. Frost & Sullivan Market Engineering Awards
- - 1. Frost & Sullivan Award for Product Differentiation Innovation
- - 2. Frost & Sullivan Award for Entrepreneurial Company
- - 3. Frost & Sullivan Award for Product Line Strategy
- - 4. Frost & Sullivan Award for Competitive Strategy Leadership
2. Osteoarthritis Viscosupplementation Products Market
- 1. Overview
- - 1. Development
- - 2. Description
- - 3. Market Drivers
- - - a. Large Market Size
- - - b. Opportunity for Market Penetration
- - - c. Patient Appeal
- - - d. Drugs Cost More and May Have Side Effects
- - - e. Aging Baby Boomers
- - - f. More Participants Entering the Market
- - - g. Expanding Indications to other Joints
- - 4. Market Challenges and Strategies
- - - a. Reimbursement Pressure from Medicare
- - - b. Physician No-confidence
- - - c. Commoditization of the Product
- - - d. Lack of Product Differentiation
- - - e. Regulatory Environment
- - - f. Threat of Tissue-engineered Products
- 2. Osteoarthritis Viscosupplementation Forecasts and Trends
- - 1. Assumptions
- - 2. Procedure Forecast
- - 3. Pricing Forecast
- - 4. Revenue Forecast
- 3. Osteoarthritis Viscosupplementation Competitive Analysis
- - 1. Market Share Analysis
- - 2. Genzyme and Wyeth Partnership
- - 3. Fidia and Sanofi-Synthelabo Partnership
- - 4. Seikagaku and Smith & Nephew Partnership
- - 5. Anika Therapeutics and Ortho Biotech Partnership
3. Ophthalmic Viscoelastic Products Market
- 1. Overview
- - 1. Development
- - 2. Description
- - 3. Market Drivers
- - - a. Demographics of Aging Population
- - - b. Proven Necessity
- - - c. Surgeon Acceptance
- - - d. Lack of Competing Technology
- - 4. Market Challenges and Strategies
- - - a. Reimbursement Pressure from Medicare
- - - b. Commoditization
- - - c. Lack of Product Differentiation
- 2. Opthalmic Viscoelastics Forecasts and Trends
- - 1. Assumptions
- - 2. Unit Shipment Forecasts
- - 3. Pricing Forecasts
- - 4. Revenue Forecasts
- 3. Ophthalmic Viscoelastics Competitive Analysis
- - 1. Market Share Analysis
- - 2. Alcon
- - 3. Advanced Medical Optics (AMO)
- - 4. Bausch & Lomb
4. Facial Aesthetic Implants Market
- 1. Overview
- - 1. Development
- - 2. Description
- - 3. Market Drivers
- - - a. Demographics of Aging Population
- - - b. Facilitates Postponing Surgical Intervention
- - - c. Patient-friendly Procedure
- - - d. Change in Attitude of Consumers
- - 4. Market Challenges and Strategies
- - - a. The Market Constantly Demands Innovation
- - - b. The Marketers are Expected to Offer A Wide Range of Products
- - - c. Unfavorable Patient Outcomes due to Misuse by Physicians
- - - d. These Procedures are not Covered for Reimbursement
- 2. Facial Aesthetics Forecasts and Trends
- - 1. Assumptions
- - 2. Unit Shipment Forecasts
- - 3. Pricing Forecasts
- - 4. Revenue Forecasts
- 3. Facial Aesthetics Competitive Analysis
- - 1. Market Share Analysis
- - 2. Inamed Corporation
- - 3. Medicis Pharmaceutical Corporation
5. Post-surgical Anti-adhesion Barriers Market
- 1. Overview
- - 1. Development
- - 2. Description
- - 3. Market Drivers
- - - a. Critical Nature of Post-surgery Adhesions
- - - b. Ease of Use
- - - c. Lack of Competitive Technologies
- - 4. Market Challenges and Strategies
- - - a. Rigorous Regulatory Procedure
- - - b. Physicians Skepticism
- - - c. Price Pressure
- 2. Forecasts and Trends
- - 1. Assumptions
- - 2. Unit Shipment Forecasts
- - 3. Pricing Forecasts
- - 4. Revenue Forecasts
- 3. Competitive Analysis
- - 1. Market Share Analysis
- - 2. Genzyme
6. Decision Support Tables
- 1. Statistics on Asian Countries
- - 1. Australia
- - 2. China
- - 3. India
- - 4. Japan
- - 5. South Korea
List Of Figures
Chapter 2
Biomaterial Applications of Hyaluronic Acid: Market Drivers for Viscosupplementation Markets Ranked in Order of Impact (U.S.), 2004-2010
Biomaterial Applications of Hyaluronic Acid: Market Challenges for Viscosupplementation Markets Ranked in Order of Impact (U.S.), 2004-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for the Number of Knee Viscosupplementation Treatment Courses (U.S.), 2003-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for the Price of Knee Viscosupplementation Treatment Courses (U.S.), 2003-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for Revenue Generated by Knee Viscosupplementation Products (U.S.), 2003-2010
Chapter 3
Biomaterial Applications of Hyaluronic Acid: Market Drivers for Ophthalmic Viscoelastic Markets Ranked in Order of Impact (U.S.), 2004-2010
Biomaterial Applications of Hyaluronic Acid: Market Challenges for Ophthalmic Viscoelastic Markets Ranked in Order of Impact (U.S.), 2004-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for Unit Shipment of Ophthalmic Viscoelastics (U.S.), 2003-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for the Unit Price of Ophthalmic Viscoelastics (U.S.), 2003-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for Revenue Generated by Ophthalmic Viscoelastics (U.S.), 2003-2010
Chapter 4
Biomaterial Applications of Hyaluronic Acid: Market Drivers for Cosmetic Dermal Filler Markets Ranked in Order of Impact (U.S.), 2004-2010
Biomaterial Applications of Hyaluronic Acid: Market Challenges for Cosmetic Dermal Filler Markets Ranked in Order of Impact (U.S.), 2004-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for Unit Shipment of Hyaluronic Acid-based Dermal Fillers (U.S.), 2003-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for the Unit Price of Hyaluronic Acid-based Dermal Fillers (U.S.), 2003-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for Revenue Generated by Hyaluronic Acid-based Dermal Fillers (U.S.), 2003-2010
Chapter 5
Biomaterial Applications of Hyaluronic Acid: Market Drivers for Hyaluronic Acid-based Post Surgical Anti-Adhesion Barrier Markets Ranked in Order of Impact (U.S.), 2004-2010
Biomaterial Applications of Hyaluronic Acid: Market Challenges for Hyaluronic Acid-based Post Surgical Anti-Adhesion Barrier Markets Ranked in Order of Impact (U.S.), 2004-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for Unit Shipment of Hyaluronic Acid-based Anti-Adhesion Barriers (U.S.), 2003-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for the Unit Price of Hyaluronic Acid-based Anti-Adhesion Barriers (U.S.), 2003-2010
Biomaterial Applications of Hyaluronic Acid: Forecasts for Revenue Generated by Hyaluronic Acid-based Anti-Adhesion Barriers (U.S.), 2003-2010
Chapter 6
Biomaterial Applications of Hyaluronic Acid: Fast Facts on Australia
Biomaterial Applications of Hyaluronic Acid: Fast Facts on China
Biomaterial Applications of Hyaluronic Acid: Fast Facts on India
Biomaterial Applications of Hyaluronic Acid: Fast Facts on Japan
Biomaterial Applications of Hyaluronic Acid: Fast Facts on South Korea
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