Contents:

LIST OF EXHIBITS IV EXECUTIVE SUMMARY ES-1 METHODOLOGY M-1 1.0 CANADIAN PERIPHERAL VASCULAR DEVICE OVERVIEW 1 1.1 Market Overview 1 1.2 Canadian Health Care System 2 1.2.1 Health Care Provision 3 1.2.2 Health Care Funding 3 1.2.3 Health Care Expenditure 3 1.3 Market Forecast 4 1.4 Market Drivers and Limiters 9 1.4.1 Market Drivers 9 1.4.2 Market Limiters 12 1.5 Trends and Issues 15 1.5.1 Regulatory Overview 15 1.5.2 SFA Treatment by Device 16 1.5.3 Endovascular PV Physician Specialists 17 1.6 Competitive Analysis 19 2.0 PERIPHERAL VASCULAR STENT MARKET 20 2.1 Market Overview 20 2.2 Market Analysis 22 2.2.1 Market Forecast 22 2.2.1.1 Iliac Artery Stenting 29 2.2.1.2 Renal Artery Stenting 29 2.2.1.3 Carotid Artery Stenting 30 2.2.1.4 Femoral-Popliteal Artery Stenting 32 2.2.1.5 Other Stenting 32 2.2.2 Market Drivers and Limiters 34 2.2.3 Trends and Issues 35 2.2.3.1 Balloon Expanding versus Self Expanding PV Stents 35 2.2.3.2 Drug-Eluting Stents 36 2.2.3.3 New Alternative Technologies .38 2.2.3.4 Complimentary Technologies .40 2.3 Competitive Analysis 41 3.0 PTA BALLOON CATHETER MARKET 44 3.1 Market Overview 44 3.2 Market Analysis 46 3.2.1 Market Forecast 46 3.2.1.1 Standard PTA Balloon Catheter Market .55 3.2.1.2 Small PTA Balloon Catheter Market .57 3.2.1.3 Large PTA Balloon Catheter Market .61 3.2.2 Market Drivers and Limiters 62 3.2.3 Trends and Issues 64 3.2.3.1 Novel PTA Devices and Applications .64 3.3 Competitive Analysis 66 4.0 EMBOLIC PROTECTION DEVICE MARKET .68 4.1 Market Overview 68 4.2 Market Analysis 71 4.2.1 Market Forecast 71 4.2.2 Market Drivers and Limiters 74 4.2.2.1 Device Complications 75 4.2.2.2 Clinical Trials 77 4.3 Competitive Analysis 80 5.0 INFERIOR VENA CAVA FILTER MARKET 85 5.1 Market Overview 85 5.2 Market Analysis 86 5.2.1 Market Forecast 86 5.2.1.1 Permanent IVCF Market 94 5.2.1.2 Retrievable IVCF Market 94 5.2.2 Market Drivers and Limiters 96 5.3 Competitive Analysis 98 6.0 AORTIC STENT GRAFT MARKET 101 6.1 Market Overview 101 6.2 Market Analysis 105 6.2.1 Market Forecast 105 6.2.1.1 Abdominal Aortic Aneurysm 110 6.2.1.2 Thoracic Aorta 116 6.2.2 Market Drivers and Limiters 119 6.3 Competitive Analysis 121 7.0 ACCESSORY DEVICE MARKET 124 7.1 Market Overview 124 7.2 Market Analysis 125 7.2.1 Market Forecast 125 7.2.1.1 PV Diagnostic Catheters .131 7.2.1.2 PV Interventional Guidewires 131 7.2.1.3 PV Diagnostic Guidewires 132 7.2.1.4 PV Guiding Catheters 132 7.2.2 Market Drivers and Limiters 133 7.3 Competitive Analysis 134 APPENDIX A: MRG ACRONYMS AND INITIALISMS 135 MRG List of Exhibits EXECUTIVE SUMMARY Exhibit ES-1: PV Device Market, by Device, Canada, 2004 ES-1 Exhibit ES-2: PV Device Market, by Device, As a % of Total, Canada, 2003– 2009 ES-2 Exhibit ES-3: PV Stent Market, by Indication, As a % of Total, Canada, 2003– 2009 ES-3 Exhibit ES-4: PTA Balloon Catheter Market, by Type, Canada, 2003–2009 ES-4 Exhibit ES-5: Carotid Stenting Procedures and Adoption of EPDs, Canada, 2003–2009 ES-5 Exhibit ES-6: Inferior Vena Cava Filter Market, by Type, Canada, 2003–2009 ES-6 Exhibit ES-7: Endovascular Aortic Repair Procedures, by Type, Canada, 2003– 2009 ES-7 Exhibit ES-9: PV Diagnostic and Interventional Procedures, Canada, 2003– 2009 ES-8 Exhibit ES-10: Leading Competitors in the PV Market, Canada, 2005 ES-9 CHAPTER 1: CANADIAN PERIPHERAL VASCULAR DEVICE OVERVIEW Exhibit 1-1: PV Device Market, Canada (US$), 2003–2009 1 Exhibit 1-2: PV Device Market, by Type, Canada (US$), 2003–2009 (Tabular Format) 5 Exhibit 1-3: PV Device Market, by Type, Canada (CD$), 2003–2009 6 Exhibit 1-4: PV Device Market Growth, by Type, Canada, 2004–2009 7 Exhibit 1-5: PV Device Market, by Type, Canada (US$), 2003–2009 (Graphical Format) 8 Exhibit 1-6: Drivers and Limiters of the PV Device Market, Canada 9 Exhibit 1-7: Over-50s as a % of the Total Population, Canada versus United States, 2000–2025 10 Exhibit 1-8: Obesity as a Percentage of Population Aged 20–64, by Province, Canada, 1994–2001 14 Exhibit 1-9: Canadian Medical Device Approval Overview 15 Exhibit 1-10: Regulatory Status of Carotid Stents and EPDs 16 Exhibit 1-11: SFA Treatment, by Device, Canada, 2003–2009 17 Exhibit 1-12: Canadian PV Procedures, by Physician Specialty 18 Exhibit 1-13: Leading Competitors in the Canadian PV Device Market, 2005 19 CHAPTER 2: PERIPHERAL VASCULAR STENT MARKET Exhibit 2-1: PV Stent Market, Canada (US$), 2003–2009 20 Exhibit 2-2: Lower Extremity Atherosclerosis Diagnosis, Canada, 2003–2009 21 Exhibit 2-3: Lower Extremity Atherosclerosis Diagnosis, by Method, Canada, 2003 21 Exhibit 2-4: PV Stent Procedures and Units, by Indication, Canada, 2003– 2009 23 Exhibit 2-5: PV Stent Market, by Indication, Canada (US$), 2003–2009 (Tabular Format) 24 Exhibit 2-6: PV Stent Market, by Indication, Canada (CD$), 2003–2009 25 Exhibit 2-7: PV Stent Market Growth, by Indication, Canada, 2004–2009 26 Exhibit 2-8: PV Stent Units and Market Value, by Indication, As a % of Total, Canada, 2003–2009 27 Exhibit 2-9: PV Stent Market, by Indication, Canada (US$), 2003–2009 (Graphical Format) 28 Exhibit 2-10: Drivers of the PV Stent Market, Canada 34 Exhibit 2-11: Limiters of the PV Stent Market, Canada 35 Exhibit 2-12: BX and SX PV Stent Use, Segmented by Indication, Canada, 2004 36 Exhibit 2-13: Leading Competitors in the PV Stent Market, Canada, 2005 41 CHAPTER 3: PTA BALLOON CATHETER MARKET Exhibit 3-1: PTA Balloon Catheter Market, Canada (US$), 2003–2009 44 Exhibit 3-2: PTA Balloon Catheter Device Overview 45 Exhibit 3-3: PTA Balloon Catheter Procedures and Units, by Use, Canada, 2003–2009 48 Exhibit 3-4: PTA Balloon Catheter Procedures, by Type and Use, As a % of Total, Canada, 2004 49 Exhibit 3-5: PTA Balloon Catheter Procedure and Unit Growth, by Use, Canada, 2004–2009 50 Exhibit 3-6: PTA Balloon Catheter Market, by Type, Canada (US$), 2003–2009 (Tabular Format) 51 Exhibit 3-7: PTA Balloon Catheter Market, by Type, Canada (CD$), 2003–2009 52 Exhibit 3-8: PTA Balloon Catheter Market Growth, by Type, Canada, 2004– 2009 53 Exhibit 3-9: PTA Balloon Catheter Market, by Type, Canada (US$), 2003–2009 (Graphical Format) 54 Exhibit 3-10: Drivers of the PTA Balloon Catheter Market, Canada 62 Exhibit 3-11: Limiters of the PTA Balloon Catheter Market, Canada 63 Exhibit 3-12: Leading Competitors in the PTA Balloon Catheter Market, Canada, 2005 66 CHAPTER 4: EMBOLIC PROTECTION DEVICE MARKET Exhibit 4-1: EPD Market, Canada (US$), 2003–2009 68 Exhibit 4-2: Advantages and Disadvantages of EPDs, by Type 69 Exhibit 4-3: Advantages and Disadvantages of EPDs, by Type (Continued) 70 Exhibit 4-4: EPD Market and Growth, Canada (US$ and CD$), 2003–2009 73 Exhibit 4-5: Drivers of the EPD Market, Canada 74 Exhibit 4-6: Limiters of the EPD Market, Canada 75 Exhibit 4-7: Capture Efficiencies of Leading Filter Basket EPDs 76 Exhibit 4-8: Important Carotid Stenting with EPD Trial Results 78 Exhibit 4-9: Overview of Carotid Stenting with EPD Trials 79 Exhibit 4-10: Leading Competitors in the EPD Market, Canada, 2005 80 Exhibit 4-11: Overview of EPDs 83 Exhibit 4-12: Overview of EPDs (Continued) 84 CHAPTER 5: INFERIOR VENA CAVA FILTER MARKET Exhibit 5-1: IVCF Market, Canada (US$), 2003–2009 85 Exhibit 5-2: Indications for IVCF Placement 87 Exhibit 5-3: Complications Associated with IVCF Use 88 Exhibit 5-4: IVCF Market, by Type, Canada (US$), 2003–2009 (Tabular Format) 90 Exhibit 5-5: IVCF Market, by Type, Canada (CD$), 2003–2009 91 Exhibit 5-6: IVCF Market Growth, by Type, Canada, 2004–2009 92 Exhibit 5-7: IVCF Market, by Type, Canada (US$), 2003–2009 (Graphical Format) 93 Exhibit 5-8: Indicated Safe Time of Removal for Retrievable IVCFs, 2004 95 Exhibit 5-9: Drivers of the IVCF Market, Canada 96 Exhibit 5-10: Limiters of the IVCF Market, Canada 97 Exhibit 5-11: Leading Competitors in the IVCF Market, Canada, 2005 98 CHAPTER 6: AORTIC STENT GRAFT MARKET Exhibit 6-1: Aortic Stent Graft Market, Canada (US$), 2003–2009 101 Exhibit 6-2: AAA Stent Graft Device Overview, Canada, 2005 102 Exhibit 6-3: US FDA Approved AAA Stent Graft Clinical Trial Overview 103 Exhibit 6-4: Thoracic Stent Graft Device Overview, Canada, 2005 104 Exhibit 6-5: Rupture Risk of Untreated AAA 105 Exhibit 6-6: Stent Graft Procedures, by Indication, Canada, 2003–2009 106 Exhibit 6-7: Aortic Stent Graft Market, by Indication, Canada (US$), 2003– 2009 107 Exhibit 6-8: Aortic Stent Graft Market, by Indication, Canada (CD$), 2003– 2009 108 Exhibit 6-9: Aortic Stent Graft Market Growth, by Indication, Canada, 2004– 2009 109 Exhibit 6-10: AAA Procedures, by Type, Canada, 2003–2009 111 Exhibit 6-11: AAA Stent Graft Penetration into Total AAA Procedures, Canada, 2003–2009 113 Exhibit 6-12: AAA Endoleak Categories and Descriptions 115 Exhibit 6-13: Drivers of the Aortic Stent Graft Market, Canada 119 Exhibit 6-14: Limiters of the Aortic Stent Graft Market, Canada 120 Exhibit 6-15: Leading Competitors in the Canadian Aortic Stent Graft Market, by Type, 2005 121 CHAPTER 7: ACCESSORY DEVICE MARKET Exhibit 7-1: Accessory Device Market, Canada (US$), 2003–2009 124 Exhibit 7-2: PV Accessory Device Market, by Type, Canada (US$), 2003–2009 (Tabular Format) 127 Exhibit 7-3: PV Accessory Device Market, by Type, Canada (CD$), 2003–2009 128 Exhibit 7-4: PV Accessory Device Market Growth, by Type, Canada, 2004–2009 129 Exhibit 7-5: PV Accessory Device Market, by Type, Canada (US$), 2003–2009 (Graphical Format) 130 Exhibit 7-6: Drivers of the PV Accessory Device Market, Canada 133 Exhibit 7-7: Limiters of the PV Accessory Device Market, Canada 133 Exhibit 7-8: Leading Competitors in the Accessory Device Market, Canada, 2005 134