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High Throughput Screening: Redefining the Mission, 2nd Edition
Drug and Market Development Publishing, May 2001, Pages: 260


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Screening of compounds has been going on for more than forty years. Advances in genomics and combinatorial chemistry during the 1990s placed large demands on HTS and spurred rapid evolution of new technologies and modalities. Although HTS has succeeded in accelerating the generation of new lead compounds, bottlenecks in the drug discovery process have now moved downstream. New challenges abound and HTS is now being called upon to contribute in areas such as early Adme and high-content cell-based analyses.

This report, High Throughput Screening: Redefining the Mission, is the fully updated and expanded 2nd edition of our original HTS report. This Report traces the evolution of HTS, provides an in-depth look at its current status, examines scenarios for future development, and gives a thorough assessment of the relationship between pharmaceutical companies and suppliers. Detailed information on the size, structure, and future development of the markets for equipment, assays, consumables, and services is supplied. In addition, the Report describes the technologies behind the instruments and assays currently in use and still on the drawing board. Emphasis is placed on new and expanding roles for HTS in the rapidly evolving drug discovery and development processes.

Unique Benefits of this Report Include:

1. Review of the history of HTS and its current status, giving an overview of this rapidly evolving field.

2. In-depth discussion of current products and technologies, identifying their attributes, advantages, and disadvantages.

3. Thorough examination of the nature of new instrument and assay technologies, highlighting their significance to the industry.

4. Comparison of miniaturization versus microfluidic approaches to HTS, presenting the pros and cons of these technologies.

5. Overview of the changing role of HTS in big pharma, outlining potential areas of opportunity.

6. Examination of HTS products and services, detailing the competitiveness of this environment.

7. Extensive profiles of key HTS players, highlighting industry leaders and strategy insights.



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