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Hidradenitis Suppurativa Market Insight, Epidemiology And Market Forecast - 2034

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    Report

  • 207 Pages
  • August 2024
  • Region: Global
  • DelveInsight
  • ID: 5006319

Key Highlights

  • To put the market opportunity for hidradenitis suppurativa into perspective for a condition that affects roughly 1% of the population, it is clear that, with the right strategy, it has the potential to be very profitable.
  • In 2023, the total market size of hidradenitis suppurativa was nearly USD ~1,400 million in the 7MM. The largest market size was captured by the US.
  • In the 7MM, the US accounted for the highest number of prevalent cases of hidradenitis suppurativa, with nearly 2,881,900 in 2023.
  • Hidradenitis suppurativa management typically involves a multidisciplinary approach, including surgery, topical or systemic antibiotics, corticosteroids, and procedural interventions like deroofing and excision.
  • Biologics have become crucial treatment options for moderate-to-severe cases, potentially altering treatment approaches. Currently, HUMIRA (adalimumab) and COSENTYX (secukinumab) are the only biologics approved by the US FDA for treating hidradenitis suppurativa. BIMZELX (bimekizumab), as of now, is only approved in Europe for treating hidradenitis suppurativa; however, the US FDA has accepted for review the sBLA for BIMZELX in April 2024 for the treatment of hidradenitis suppurativa.
  • HUMIRA, AbbVie’s flagship product, is a classic example of maintaining a market monopoly for an extended period. However, the introduction of biosimilars has significantly affected HUMIRA’s sales in the 7MM. In Europe and Japan, HUMIRA biosimilars were launched in 2018 and 2021. In January 2023, AMJEVITA became the first HUMIRA biosimilar to be launched in the US.
  • Although BIMZELX is more effective, COSENTYX has the first-mover advantage. According to reports, COSENTYX is experiencing strong launch momentum. It is worth highlighting that BIMZELX's efficacy is differentiated to both HUMIRA and COSENTYX. Although Novartis' clearance has allowed COSENTYX some leeway in treating hidradenitis suppurativa, UCB’s BIMZELX, which yielded "incrementally better" outcomes than COSENTYX, might pose a serious threat to the medication in the near future.
  • The hidradenitis suppurativa market is experiencing rapid growth, driven by an influx of pipeline therapeutics. The diverse pipeline includes treatments targeting interleukins (such as IL-17, IL-36, and IL-1a/b), PDE4 inhibitors, JAK inhibitors, and CXCR1/CXCR2 inhibitors.
  • For moderate-to-severe and biologic experiences, many therapies, including Izokibep (ACELYRIN), Sonelokimab (MoonLake Immunotherapeutics), Povorcitinib (Incyte Corporation), Spesolimab (Boehringer Ingelheim), Lutikizumab (AbbVie), Eltrekibart (Eli Lilly) and others are being investigated.
  • Povrocitinib may become the first oral medication to enter this rapidly expanding market. The outcomes of Povrocitinib outperform those of RINVOQ.
  • Among the few top data presented on hidradenitis suppurativa at the American Academy of Dermatology 2024 conference includes Incyte Corporation’s Phase II study evaluating ruxolitinib 1.5% cream for hidradenitis suppurativa and 24-week topline results from the Phase II MIRA trial evaluating sonelokimab.
  • Since nanobodies may target many pathways and have superior tissue penetration, there is a lot of enthusiasm for nanobodies because of their potential to treat hidradenitis suppurativa. The potential for Sonelokimab to replace COSENTYX exists if Moonlake's Phase II findings are similarly replicated in Phase III.
  • Despite the considerable impact on patients' well-being, the mild segment is still untapped without any approved therapy and only two emerging therapies, namely, orismilast and ruxolitinib cream.
The " Hidradenitis Suppurativa - Market Insight, Epidemiology, and Market Forecast - 2034" report delivers an in-depth understanding of hidradenitis suppurativa, historical and forecasted epidemiology as well as the hidradenitis suppurativa market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

The hidradenitis suppurativa market report provides current treatment practices, emerging drugs, hidradenitis suppurativa share of individual therapies, and current and forecasted hidradenitis suppurativa market size from 2020 to 2034, segmented by seven major markets. The report also covers hidradenitis suppurativa treatment practices/algorithms and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.

Geography Covered

  • The United States
  • EU4 (Germany, France, Italy, and Spain) and the United Kingdom
  • Japan

Study Period: 2020-2034

Hidradenitis Suppurativa Disease Understanding and Treatment Algorithm

Hidradenitis Suppurativa Overview

Hidradenitis suppurativa is a chronic condition characterized by swollen, painful lesions occurring in the armpit, groin, anal and breast regions. It is a painful and long-term skin condition causing abscesses and scarring on the skin. Affected patients may present with acute abscesses, but the condition often progresses to a chronic state with persistent pain, sinus tract fistula formation, and scarring. It is usually associated with depression and severe overall impairment of quality of life (QoL), exceeding other skin disorders heavily impacting QoL, such as psoriasis, atopic dermatitis, alopecia, and acne.

There are several scoring systems for the assessment of disease severity of hidradenitis suppurativa, including Hurley staging, Physician’s Global Assessment (PGA), the modified Sartorius score (MSS), and hidradenitis suppurativa Severity Index (HSSI). Based on Hurley staging, the disease is characterized by three clinical stages, i.e., Hurley stages 1, 2, and 3.

Hidradenitis Suppurativa Diagnosis

The diagnosis is primarily clinical, based on symptoms reported by the patient and signs observed by the physician. No pathognomonic test exists, and biopsy is rarely required, especially in well-developed lesions. Primary diagnosis of hidradenitis suppurativa involves identification of the disease and assessment of its comorbidities. Fulfilment of three criteria is necessary for the diagnosis of hidradenitis suppurativa:

Typical lesions: deep-seated, painful nodules

Characteristic distribution: Typical anatomical predilection (i.e., axillae, groins, perineal and p

erianal regions, buttocks, infra-mammary and inter-mammary folds)

Recurrence: Chronicity and recurrence of lesions.

In certain situations, a biopsy is required to confirm the diagnosis, such as in the atypical cases of perianal Crohn's disease, tuberculous ulcer, and carcinoma. The association with spinocellular carcinoma, in case of long-term progress, is very rare.

Hidradenitis Suppurativa Treatment

The overall treatment goals for hidradenitis suppurativa include alleviating lesion-related symptoms (e.g., pain), reducing recurrence frequency and new lesion formation, and preventing disease and comorbidity progression.

Based upon the published guidelines for hidradenitis suppurativa, the first line of therapy includes topical clindamycin, oral clindamycin/rifampicin, tetracycline, and SC adalimumab. A similar approach was taken for the second-line therapies, including zinc gluconate, resorcinol, intralesional corticosteroids, infliximab, acitretin, and etretinate. Third-line therapies included colchicine, botulinum toxin, isotretinoin, dapsone, cyclosporine, and hormones. Surgical evaluated therapies included individual lesions excision, total excision of lesions surrounding hair-bearing skin, secondary intention healing, primary closure, reconstructive with skin grafting and NPWT reconstruction with flap, deroofing, carbon dioxide laser therapy, laser therapy, and intense pulsed light.

The preferred biologic agent for hidradenitis suppurativa is HUMIRA (adalimumab), as it is backed by extensive research. Other approved therapies include COSENTYX and BIMZELX to treat moderate-to-severe hidradenitis suppurativa in adults..

Hidradenitis Suppurativa Epidemiology

The hidradenitis suppurativa epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by the Total Prevalent Cases of Hidradenitis Suppurativa, Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa, Gender-Specific Prevalent Cases of Hidradenitis Suppurativa, Age-specific Prevalent Cases of Hidradenitis Suppurativa, Stage-specific Prevalent cases of Hidradenitis Suppurativa, and Treated Prevalent Cases of Hidradenitis Suppurativa in the 7MM market covering the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan from 2020 to 2034.
  • In 2023, the total prevalent cases of hidradenitis suppurativa in the 7MM were nearly 6.2 million. These cases are anticipated to increase by 2034.
  • In the 7MM, the US accounted for the highest number of diagnosed prevalent cases of hidradenitis suppurativa, with nearly 877,600 in 2023.
  • Among EU4 and the UK, Germany accounted for the highest number of diagnosed prevalent cases of hidradenitis suppurativa, whereas Spain occupied the bottom of the ladder.
  • In the US, EU4 and the UK, hidradenitis suppurativa was seen to be slightly more common in females (~75%) than males (~25%). Conversely, in Japan, males represent nearly 70% of the total cases, while females account for around 30%.
  • The age-specific data revealed that hidradenitis suppurativa was most prevalent in the age group of 30-39 years, which was nearly 26% of the total diagnosed cases of hidradenitis suppurativa in the US.
  • Among all, Hurley Stage I was observed to be most prevalent, with approximately 480,000 cases in 2023 in the US.

Hidradenitis Suppurativa Drug Chapters

The drug chapter segment of the hidradenitis suppurativa report encloses a detailed analysis of the late-stage (Phase III and Phase II) and early-stage (Phase I/II) pipeline drugs. The current key players for emerging drugs and their respective drug candidates include Incyte Corporation (Povorcitinib), Acelyrin (Izokibep), AbbVie (Upadacitinib; Lutikizumab), MoonLake Immunotherapeutics (Sonelokimab), UNION therapeutics (Orismilast), Eli Lilly (Eltrekibart), Incyte Corporation (Ruxolitinib 1.5% Cream), and others. The drug chapter also helps understand the hidradenitis suppurativa clinical trial details, expressive pharmacological action, agreements and collaborations, approval, and patent details, and the latest news and press releases.

Marketed Drugs

HUMIRA (adalimumab): AbbVie/Eisai

HUMIRA (adalimumab) is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor (TNF). In September 2015, the US FDA approved HUMIRA for the treatment of moderate-to-severe hidradenitis suppurativa in adults, and later in October 2018, for patients =12 years of age as well. The recommended dose of HUMIRA for adult patients with hidradenitis suppurativa is an initial dose of 160 mg (given in 1 day or split over 2 consecutive days), followed by 80 mg 2 weeks later. In Europe and Japan, HUMIRA biosimilars were launched in 2018 and 2021. In September 2016, AMJEVITA became the first FDA-approved biosimilar for HUMIRA. Then, in January 2023, it became the first HUMIRA biosimilar to be launched in the US.

BIMZELX (bimekizumab): UCB Biopharma

Bimekizumab is the first humanized monoclonal IgG1 antibody that potently and selectively neutralizes both IL-17A and IL-17F, two key cytokines driving inflammatory processes. In April 2024, UCB announced that the European Commission granted marketing authorization for BIMZELX for the treatment of active moderate-to-severe hidradenitis suppurativa in adults with an inadequate response to conventional systemic hidradenitis suppurativa therapy. The approval follows a positive opinion issued in March 2024 by the Committee for Medicinal Products for Human Use of the EMA. In addition, in April 2024, the US FDA accepted for review the sBLA for BIMZELX for the treatment of adults with moderate-to-severe hidradenitis suppurativa. The drug has also been filed with PMDA in Japan for treating hidradenitis suppurativa.

Emerging Drugs

Povorcitinib (INCB054707): Incyte Corporation

Povorcitinib, developed by Incyte Corporation, is a selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules to treat patients with moderate-to-severe hidradenitis suppurativa. This therapeutic molecule is administered orally. Currently, the company is investigating this molecule in three different Phase III clinical trials (STOP-HS studies) for moderate-to-severe hidradenitis suppurativa. The company expects the Phase III STOP-HS trial data in 2025. In addition, the company also anticipates the potential launch of povorcitinib for hidradenitis suppurativa by 2026-2027.

Sonelokimab (M1095): MoonLake Immunotherapeutics

Sonelokimab (M1095) is an investigational ~40 kDa humanized nanobody consisting of three VHH domains covalently linked by flexible glycine-serine spacers. Nanobodies represent a new generation of antibody-derived targeted therapies. With two domains, sonelokimab selectively binds with high affinity to IL-17A and IL-17F, thereby inhibiting the naturally occurring IL-17A/A, IL-17A/F, and IL-17F/F dimers.

The company has already completed a Phase II trial of sonelokimab for treating moderate-to-severe hidradenitis suppurativa and is currently evaluating the drug in two Phase III clinical trials. The 24-week topline results were presented at the AAD 2024 annual meeting. The initiation of this Phase III program follows the announcement in February 2024 of the successful outcome of MoonLake’s end-of-Phase II interactions with the US FDA, as well as positive feedback from the EMA, supporting MoonLake’s proposed approach for advancing its Phase III program in hidradenitis suppurativa. The Phase III VELA program is expected to enroll 800 patients across VELA-1 and VELA-2. This is the first Phase III program in hidradenitis suppurativa to use the higher clinical response level of HiSCR75 as the primary endpoint. As per the company, the topline primary endpoint readout of the Phase III VELA trial at Week 16, together with data on other endpoints, is expected as of mid-2025.

Drug Class Insight

Hidradenitis suppurativa is treated using a variety of therapeutic classes tailored to its severity. Topical treatments, including antibiotics and antiseptics, are often used for milder cases. Systemic therapies, such as oral antibiotics, hormonal treatments, and retinoids, are utilized for more extensive disease. Biologic therapies, particularly TNF-alpha inhibitors and interleukin inhibitors, are effective for moderate-to-severe hidradenitis suppurativa. Immunosuppressants like cyclosporine and methotrexate are also options.

The diverse pipeline includes treatments targeting interleukins (such as IL-17, IL-36, and IL-1a/b), PDE4 inhibitors, JAK inhibitors, and CXCR1 and CXCR2 inhibitors.

Hidradenitis Suppurativa Market Outlook

As there is no cure for hidradenitis suppurativa, early diagnosis, and treatment help prevent the disease from getting worse and forming additional scars, and the current treatment approaches depend on the severity and clinical staging of the disease. Regarding pharmacological treatment market options, the following therapies are available: topical and systemic antibiotics, corticosteroids, hormonal therapy, systemic retinoids, zinc supplements, and immunosuppressive agents, including biologics. The mainstay of medical treatment of mild disease involves antibacterial washes and topical antibiotics. Acute flares may be managed by intralesional corticosteroids and/or minor surgical procedures. Oral therapies for mild-to-moderate hidradenitis suppurativa include extended courses of broad-spectrum antibiotics and systemic retinoids. In off-label therapies, the commonly used antibiotics are clindamycin, rifampicin, and tetracycline, as these antibiotics have shown their efficacy in the studies.

Currently, the established therapies in the market include BIMZELX (bimekizumab), COSENTYX (secukinumab), and HUMIRA (adalimumab). HUMIRA was completely dominating the market until 2023, even though its composition-of-matter patent expired in December 2016 in the US; AbbVie has stronger surrounding patents stateside than in Europe, giving them more layers of defense on the biologic’s exclusivity. However, in June 2023, the European Commission approved COSENTYX, an IL-17A monoclonal antibody, for use in adults with active moderate-to-severe hidradenitis suppurativa and an inadequate response to conventional systemic hidradenitis suppurativa therapy. The drug was later approved by the US FDA in October 2023 to treat moderate-to-severe hidradenitis suppurativa in adults. Recently, in April 2024, UCB announced that the European Commission granted marketing authorization for BIMZELX for the treatment of active moderate-to-severe hidradenitis suppurativa in adults with an inadequate response to conventional systemic hidradenitis suppurativa therapy.

The emerging pipeline of hidradenitis suppurativa therapies includes promising candidates such as povorcitinib (INCB054707), Spesolimab (BI 655130), Lutikizumab, Eltrekibart, Orismilast, ruxolitinib cream, Izokibep, Sonelokimab, and others.
  • The Hidradenitis suppurativa market is currently underserved. It is anticipated that similar to rheumatoid arthritis, hidradenitis suppurativa has a sufficiently large market to support the co-existence of several blockbuster medications.
  • If the efficacy of oral drugs is largely comparable to SC injections, there may be a preference for oral therapies in this underappreciated market.
  • The US accounted for the largest market size of hidradenitis suppurativa in the 7MM, with nearly USD 1.10 billion in 2023.
  • Among EU4 and the UK, Germany accounted for the maximum market size in 2023, while Spain occupied the bottom of the ladder.
  • Patient share of overall adalimumab is also expected to decline due to the recent entry of COSENTYX and the upcoming BIMZELX.
  • In the US, by 2034, among all the therapies, the highest revenue is expected to be generated from BIMZELX.

Hidradenitis Suppurativa Drugs Uptake

This section focuses on the rate of uptake of the potential drugs expected to be launched in the market during the study period. The analysis covers hidradenitis suppurativa market uptake by drugs, patient uptake by therapies, and sales of each drug. The probability of success in the case of emerging drugs in the case of hidradenitis suppurativa is low, considering the lack of data available on proof of concept studies.

The emerging class in hidradenitis suppurativa treatment involves IL-17 inhibitors, with dual inhibition of IL-17A and IL-17F showing the most promise. Clinical data indicates that COSENTYX (secukinumab), which targets only IL-17A, is less effective than BIMZELX (bimekizumab), which inhibits both IL-17A and IL-17F. This underscores the pivotal role of IL-17 cytokines and demonstrates the potential of this class to have a strong uptake.

For mild to moderate hidradenitis suppurativa, ruxolitinib is expected to have a better uptake compared to orismilast, as ruxolitinib cream has demonstrated superior efficacy and safety.

Hidradenitis Suppurativa Pipeline Development Activities

The report provides insights into different therapeutic candidates in Phase III, Phase II, and Phase I/II stage. It also analyzes key players involved in developing targeted therapeutics.

Pipeline Development Activities

The report covers detailed information on collaborations, acquisitions and mergers, licensing, and patent details for hidradenitis suppurativa emerging therapies.

KOL Views

To keep up with current market trends, we take KOLs and SMEs' opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Some of the leaders like MD, Professor and Vice Chair of the Department of Dermatology and Director, PhD, and others. Their opinion helps to understand and validate current and emerging therapies and treatment patterns or hidradenitis suppurativa market trends. This will support the clients in potential upcoming novel treatments by identifying the overall scenario of the market and the unmet needs.

The analysts connected with 30+ KOLs to gather insights; however, interviews were conducted with 10+ KOLs in the 7MM. Centers such as the Department of Dermatology, CHA Bundang Medical Center, Department of Dermatology & Academic Wound Healing, Cardiff University, University of California, University of London, etc., were contacted. Their opinion helps understand and validate hidradenitis suppurativa epidemiology and market trends.

Qualitative Analysis

We perform qualitative and market intelligence analysis using various approaches, such as SWOT and conjoint analysis. In the SWOT analysis, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provided. These pointers are based on the analyst’s discretion and assessment of the patient burden, cost analysis, and existing and evolving treatment landscape.

The analyst analyzes multiple emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry.

In efficacy, the trial’s primary and secondary outcome measures are evaluated.

Further, the therapies’ safety is evaluated wherein the acceptability, tolerability, and adverse events are majorly observed, and it sets a clear understanding of the side effects posed by the drug in the trials.

Market Access and Reimbursement

HUMIRA (adalimumab) - a complex medication - is an expensive drug that costs about USD 7,389 for two SC kits (10 mg/0.1 mL); possessing insurance or a discount card aids the patient in paying less. Most insurance plans cover HUMIRA, but individual plans may vary in the coverage range. Insurance can lower the out-of-pocket price of HUMIRA from about USD 7,389 to approximately USD 5,000 per month. Some people who receive employer/retiree commercial prescription coverage will be eligible for a HUMIRA Complete Savings Card. The HUMIRA Complete Savings card is only available to people with private insurance coverage from their employer or to people who have purchased insurance coverage directly from insurance companies. Co-pay assistance is unavailable for people who receive prescription reimbursement through federal, state, or government-funded insurance programs.

COSENTYX Connect is a free, personalized support program for people taking or considering COSENTYX. The goal is to make the COSENTYX experience as easy, affordable, and convenient as possible and pay as little as USD 0 co-pay if eligible. COSENTYX Connect Co-Pay Program provides up to USD 16,000 annually for the cost of COSENTYX and up to USD 150 per infusion (up to USD 1,950 annually) for the cost of administration.

Scope of the Report

  • The report covers a descriptive overview of hidradenitis suppurativa, explaining its causes, signs and symptoms, pathogenesis, and currently available therapies.
  • Comprehensive insight has been provided into hidradenitis suppurativa epidemiology and treatment.
  • Additionally, an all-inclusive account of both the current and emerging therapies for hidradenitis suppurativa is provided, along with the assessment of new therapies that will have an impact on the current treatment landscape.
  • A detailed review of the hidradenitis suppurativa market, historical and forecasted, is included in the report, covering the 7MM drug outreach.
  • The report provides an edge while developing business strategies by understanding trends shaping and driving the 7MM hidradenitis suppurativa market.

Hidradenitis Suppurativa Report Insights

Hidradenitis Suppurativa Report Insights

  • Patient Population
  • Therapeutic Approaches
  • Hidradenitis Suppurativa Pipeline Analysis
  • Hidradenitis Suppurativa Market Size and Trends
  • Market Opportunities
  • Impact of Upcoming Therapies

Hidradenitis Suppurativa Report Key Strengths

  • Eleven Years Forecast
  • The 7MM Coverage
  • Hidradenitis Suppurativa Epidemiology Segmentation
  • Key Cross Competition
  • Highly Analyzed Market
  • Drugs Uptake

Hidradenitis Suppurativa Report Assessment

  • Current Treatment Practices
  • Unmet Needs
  • Pipeline Product Profiles
  • Market Attractiveness
  • Qualitative Analysis (SWOT and Conjoint Analysis)

FAQs

  • What was the hidradenitis suppurativa market share (%) distribution in 2020, and what would it look like by 2034?
  • What would be the hidradenitis suppurativa total market size as well as market size by therapies across the 7MM during the study period (2020-2034)?
  • What are the key findings about the market across the 7MM, and which country will have the largest hidradenitis suppurativa market size during the study period (2020-2034)?
  • At what CAGR, the hidradenitis suppurativa market is expected to grow at the 7MM level during the study period (2020-2034)?
  • What are the disease risks, burdens, and unmet needs of hidradenitis suppurativa?
  • What is the historical hidradenitis suppurativa patient pool in the United States, EU4 (Germany, France, Italy, and Spain) and the UK, and Japan?
  • What would be the forecasted patient pool of hidradenitis suppurativa at the 7MM level?
  • What will be the growth opportunities across the 7MM concerning the patient population of hidradenitis suppurativa?
  • Amon the 7MM, which country would have the most prevalent cases of hidradenitis suppurativa during the study period (2020-2034)?
  • How many companies are developing therapies for the treatment of hidradenitis suppurativa?
  • How many emerging therapies are in the mid-stage and late stage of development for the treatment of hidradenitis suppurativa?
  • What are the key collaborations (industry-industry, industry-academia), Mergers and acquisitions, and licensing activities related to hidradenitis suppurativa therapies?
  • What are the recent novel therapies, targets, mechanisms of action, and technologies developed to overcome the limitations of existing therapies?
  • What are the approved biosimilars for HUMIRA?
  • What are the clinical studies going on for hidradenitis suppurativa and their status?
  • What are the 7MM historical and forecasted market of hidradenitis suppurativa?

Reasons to buy

  • The report will help in developing business strategies by understanding trends shaping and driving the hidradenitis suppurativa market.
  • To understand the future market competition in the hidradenitis suppurativa market and an insightful review of the SWOT analysis of hidradenitis suppurativa.
  • Organize sales and marketing efforts by identifying the best opportunities for hidradenitis suppurativa in the US, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.
  • Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors.
  • Organize sales and marketing efforts by identifying the best opportunities for the hidradenitis suppurativa market.
  • To understand the future market competition in the hidradenitis suppurativa market.

Table of Contents

1. Key Insights2. Report Introduction
3. Hidradenitis Suppurativa Market Overview at a Glance: 7MM
3.1. Market Share by Therapies (%) Distribution of Hidradenitis Suppurativa in 2020
3.2. Market Share by Therapies (%) Distribution of Hidradenitis Suppurativa in 2034
4. Executive Summary of Hidradenitis Suppurativa5. Key Events6. Epidemiology and Market Methodology
7. Disease Overview: Hidradenitis Suppurativa
7.1. Introduction
7.2. Causes and Symptoms of Hidradenitis Suppurativa
7.3. Classification and Severity Assessment of Hidradenitis Suppurativa
7.3.1. Hurley Stages of hidradenitis suppurativa
7.3.2. Modified Sartorius Score (MSS) of hidradenitis suppurativa
7.3.3. Physician Global Assessment of Hidradenitis Suppurativa
7.3.4. Specific Severity Index of Hidradenitis Suppurativa (HSSI)
7.4. Pathophysiology of Hidradenitis Suppurativa
7.5. Genetic Basis of Hidradenitis Suppurativa
7.6. Diagnosis of Hidradenitis Suppurativa
7.6.1. Differential Diagnosis
7.7. Biomarkers of Hidradenitis Suppurativa
7.8. Risk Factors and Complications
7.9. Comorbidities
8. Treatment and Guidelines
8.1. S2k Guideline for the Treatment of Hidradenitis Suppurativa/ Acne Inversa (2024): Germany
8.2. European S1 Guideline for the Treatment of Hidradenitis Suppurativa/Acne Inversa: (2015)
8.3. North American Clinical Management Guidelines for Hidradenitis Suppurativa: (2019)
8.4. British Association of Dermatologists Guidelines for the Management of Hidradenitis Suppurativa (Acne Inversa): (2018)
8.5. Guidelines for the Management of Hidradenitis Suppurativa: Recommendations Supported by the Centre of Evidence of the French Society of Dermatology: (2021)
8.6. Hidradenitis Suppurativa/Acne Inversa: A Practical Framework for Treatment Optimization - Systematic Review and Recommendations from the Hidradenitis Suppurativa Alliance Working Group: (2018)
9. Epidemiology and Patient Population
9.1. Key Findings
9.2. Assumptions and Rationale: 7MM
9.3. Total Prevalent Cases of Hidradenitis Suppurativa in the 7MM
9.4. Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in the 7MM
9.5. The United States
9.5.1. Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in the US
9.5.2. Gender-specific Prevalent Cases of Hidradenitis Suppurativa in the US
9.5.3. Age-specific Prevalent Cases of Hidradenitis Suppurativa in the US
9.5.4. Stage-specific Prevalent Cases of Hidradenitis Suppurativa in the US
9.5.5. Total Treated Prevalent Cases of Hidradenitis Suppurativa in the US
9.6. EU4 and the UK
9.6.1. Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK
9.6.2. Gender-specific Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK
9.6.3. Age-specific Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK
9.6.4. Stage-specific Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK
9.6.5. Total Treated Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK
9.7. Japan
9.7.1. Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in Japan
9.7.2. Gender-specific Prevalent Cases of Hidradenitis Suppurativa in Japan
9.7.3. Age-specific Prevalent Cases of Hidradenitis Suppurativa in Japan
9.7.4. Stage-specific Prevalent Cases of Hidradenitis Suppurativa in Japan
9.7.5. Total Treated Prevalent Cases of Hidradenitis Suppurativa in Japan
10. Patient Journey of Hidradenitis Suppurativa11. Key Endpoints in Hidradenitis Suppurativa Clinical Trials
12. Marketed Drugs
12.1. Key Competitors
12.2. HUMIRA (adalimumab): AbbVie/Eisai
12.2.1. Product Description
12.2.2. Regulatory milestones
12.2.3. Other Developmental Activities
12.2.4. Safety and Efficacy
12.3. COSENTYX (secukinumab): Novartis
12.3.1. Product Description
12.3.2. Regulatory Milestone
12.3.3. Other Developmental Activities
12.3.4. Clinical Development
1.1.1.1. Clinical Trials Information
12.3.5. Safety and Efficacy
12.5. BIMZELX (bimekizumab): UCB Biopharma
12.5.1. Product description
12.5.2. Regulatory Milestone
12.5.3. Other developmental Activities
12.5.4. Clinical Development
12.5.4.1. Clinical Trials Information
12.5.5. Safety and efficacy
13. Emerging Drugs
13.1. Key Cross
13.2. Povorcitinib (INCB054707): Incyte Corporation
13.2.1. Product Description
13.2.2. Other Developmental Activities
13.2.3. Clinical Development
13.2.3.1. Clinical Trials Information
13.2.4. Safety and Efficacy
13.3. Izokibep: ACELYRIN
13.3.1. Product Description
13.3.2. Other Developmental Activities
13.3.3. Clinical Development
13.3.3.1. Clinical Trials Information
13.3.4. Safety and Efficacy
13.4. RINVOQ (upadacitinib): AbbVie
13.4.1. Product Description
13.4.2. Other Developmental Activities
13.4.3. Clinical Development
13.4.3.1. Clinical Trials Information
13.4.4. Safety and Efficacy
13.5. Lutikizumab (ABT-981): AbbVie
13.5.1. Product description
13.5.2. Clinical Development
13.5.2.1. Clinical Trial Information
13.5.3. Safety and Efficacy
13.6. Sonelokimab (M1095): MoonLake Immunotherapeutics
13.6.1. Product Description
13.6.2. Other Developmental Activity
13.6.3. Clinical Development
13.6.3.1. Clinical Trial Information
13.6.4. Safety and Efficacy
13.7. Spesolimab: Boehringer Ingelheim
13.7.1. Product Description
13.7.2. Clinical Development
13.7.2.1. Clinical Trials Information
13.7.3. Safety and Efficacy
13.8. Brepocitinib (PF-06700841): Priovant Therapeutics
13.8.1. Product Description
13.8.2. Clinical Development
13.8.2.1. Clinical Trial Information
13.8.3. Safety and Efficacy
13.9. Eltrekibart (LY3041658): Eli Lilly
13.9.1. Product Description
13.9.2. Clinical Development
13.9.2.1. Clinical Trial Information
13.9.3. Safety and Efficacy
13.1. Ruxolitinib 1.5% Cream: Incyte Corporation
13.10.1. Product Description
13.10.2. Other Developmental Activities
13.10.3. Clinical Development
13.10.3.1. Clinical Trial Information
13.10.4. Safety and Efficacy
13.11. SAR-444656/KT-474: Sanofi/Kymera Therapeutics
13.11.1. Product Description
13.11.2. Other Developmental Activities
13.11.3. Clinical Development
13.11.3.1. Clinical Trial Information
13.11.4. Safety and Efficacy
13.12. Orismilast: UNION Therapeutics
13.12.1. Product Description
13.12.2. Other Developmental Activities
13.12.3. Clinical Development
13.12.3.1. Clinical Trials Information
13.12.4. Safety and Efficacy
14. Hidradenitis Suppurativa: Market Analysis
14.1. Key Findings
14.2. Market Outlook
14.3. Conjoint Analysis
14.4. Key Market Forecast Assumptions
14.5. Total Market Size of Hidradenitis Suppurativa in the 7MM
14.6. United States Market Size
14.6.1. Total Market Size of Hidradenitis Suppurativa in the United States
14.6.2. Market Size of Hidradenitis Suppurativa by Therapies in the United States
14.7. EU4 and the UK Market Size
14.7.1. Total Market Size of Hidradenitis Suppurativa in EU4 and the UK
14.7.2. Market Size of Hidradenitis Suppurativa by Therapies in EU4 and the UK
14.8. Japan Market Size
14.8.1. Total Market Size of Hidradenitis Suppurativa in Japan
14.8.2. Market Size of Hidradenitis Suppurativa by Therapies in Japan
15. Market Access and Reimbursement
15.1. United States
15.1.1. HUMIRA Reimbursement Program
15.2. Co-payment in the European Countries
15.3. The National Institute for Health and Care Excellence (NICE): UK
15.4. Institute for Quality and Efficiency in Healthcare (IQWiG): Germany
15.5. Haute Autorité de Santé (HAS): France
15.6. Italian Medicines Agency (AIFA): Italy
15.7. Spanish Agency of Medicines and Medical Products (AEMPS): Spain
16. Unmet Needs17. SWOT Analysis18. KOL Views
19. Appendix
19.1. Bibliography
19.2. Report Methodology
20. Publisher Capabilities21. Disclaimer22. About the Publisher
List of Tables
Table 1: Summary of Hidradenitis Suppurativa Market and Epidemiology (2020-2034)
Table 2: Hurley Staging System
Table 3: Modified Sartorius Score of Hidradenitis Suppurativa
Table 4: Physician Global Assessment of Hidradenitis Suppurativa
Table 5: Specific Severity Index of Hidradenitis Suppurativa (HSSI)
Table 6: Differential Diagnosis of Hidradenitis Suppurativa
Table 7: Recommendations for Medical Treatment of Hidradenitis Suppurativa
Table 8: Recommendations for Surgical Treatment of Hidradenitis Suppurativa
Table 9: Total Prevalent Cases of Hidradenitis Suppurativa in the 7MM, in thousand (2020-2034)
Table 10: Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in the 7MM, in thousand (2020-2034)
Table 11: Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in the US, in thousand (2020-2034)
Table 12: Gender-specific Prevalent Cases of Hidradenitis Suppurativa in the US, in thousand (2020-2034)
Table 13: Age-specific Prevalent Cases of Hidradenitis Suppurativa in the US, in thousand (2020-2034)
Table 14: Stage-specific Prevalent Cases of Hidradenitis Suppurativa in the US, in thousand (2020-2034)
Table 15: Total Treated Prevalent Cases of Hidradenitis Suppurativa in the US, in thousand (2020-2034)
Table 16: Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK, in thousand (2020-2034)
Table 17: Gender-specific Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK, in thousand (2020-2034)
Table 18: Age-specific Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK (2020-2034)
Table 19: Stage-specific Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK, in thousand (2020-2034)
Table 20: Total Treated Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK (2020-2034)
Table 21: Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in Japan (2020-2034)
Table 22: Gender-specific Prevalent Cases of Hidradenitis Suppurativa in Japan (2020-2034)
Table 23: Age-specific Prevalent Cases of Hidradenitis Suppurativa in Japan (2020-2034)
Table 24: Stage-specific Prevalent Cases of Hidradenitis Suppurativa in Japan (2020-2034)
Table 25: Total Treated Prevalent Cases of Hidradenitis Suppurativa in Japan (2020-2034)
Table 26: Marketed Drugs Key Cross
Table 27: COSENTYX, Clinical Trial Description, 2024
Table 28: BIMZELX (bimekizumab), Clinical Trial Description, 2024
Table 29: Key Cross of Emerging Therapies
Table 30: Povorcitinib (INCB054707), Clinical Trial Description, 2024
Table 31: Izokibep, Clinical Trial Description, 2024
Table 32: RINVOQ (upadacitinib), Clinical Trial Description, 2024
Table 33: Lutikizumab (ABT-981), Clinical Trial Description, 2024
Table 34: Sonelokimab, Clinical Trial Description, 2024
Table 35: Spesolimab, Clinical Trial Description, 2024
Table 36: Brepocitinib (PF-06700841), Clinical Trial Description, 2024
Table 37: Eltrekibart (LY3041658), Clinical Trial Description, 2024
Table 38: Ruxolitinib 1.5% Cream, Clinical Trial Description, 2024
Table 39: SAR-444656/KT-474, Clinical Trial Description, 2024
Table 40: Orismilast, Clinical Trial Description, 2024
Table 41: Off-label Therapies Used in Hidradenitis Suppurativa Treatment
Table 31: Key Market Forecast Assumption of Hidradenitis Suppurativa in the United States
Table 32: Key Market Forecast Assumption of Hidradenitis Suppurativa in EU4 and the UK
Table 31: Key Market Forecast Assumption of Hidradenitis Suppurativa in Japan
Table 42: Total Market Size of Hidradenitis Suppurativa in the 7MM, USD million (2020-2034)
Table 43: Total Market Size of Hidradenitis Suppurativa in the US, USD million (2020-2034)
Table 44: Market Size of Hidradenitis Suppurativa by Therapies in the US, USD million (2020-2034)
Table 45: Total Market Size of Hidradenitis Suppurativa in EU4 and the UK, USD million (2020-2034)
Table 46: Market Size of Hidradenitis Suppurativa by Therapies in EU4 and the UK, USD million (2020-2034)
Table 47: Total Market Size of Hidradenitis Suppurativa in Japan, USD million (2020-2034)
Table 48: Market Size of Hidradenitis Suppurativa by Therapies in Japan, USD million (2020-2034)
Table 49: Co-payment in the European Countries
Table 50: NICE Assessment for Hidradenitis Suppurativa Therapy
Table 51: IQWiG Assessment for Hidradenitis Suppurativa Therapy
Table 52: HAS Assessment for Hidradenitis Suppurativa Therapy
Table 53: Market Access and Reimbursement Scenario of Adalimumab Biosimilars in France
Table 54: AIFA Assessment for Hidradenitis Suppurativa Therapy
Table 55: AEMPS Assessment for Hidradenitis Suppurativa Therapy
List of Figures
Figure 1: Disease Burden in the Patient with Hidradenitis Suppurativa
Figure 2: Stages of Hidradenitis Suppurativa
Figure 3: Pathophysiology of hidradenitis suppurativa
Figure 4: Risk Factors of hidradenitis suppurativa
Figure 5: Comorbidities in Hidradenitis Suppurativa
Figure 6: Treatment Options for Hidradenitis Suppurativa
Figure 7: Total Prevalent Cases of Hidradenitis Suppurativa in the 7MM (2020-2034)
Figure 8: Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in the 7MM (2020-2034)
Figure 9: Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in the US (2020-2034)
Figure 10: Gender-specific Prevalent Cases of Hidradenitis Suppurativa in the US (2020-2034)
Figure 11: Age-specific Prevalent Cases of Hidradenitis Suppurativa in the US (2020-2034)
Figure 12: Stage-specific Prevalent Cases of Hidradenitis Suppurativa in the US (2020-2034)
Figure 13: Total Treated Prevalent Cases of Hidradenitis Suppurativa in the US (2020-2034)
Figure 14: Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK (2020-2034)
Figure 15: Gender-specific Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK (2020-2034)
Figure 16: Age-specific Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK (2020-2034)
Figure 17: Stage-specific Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK (2020-2034)
Figure 18: Total Treated Prevalent Cases of Hidradenitis Suppurativa in EU4 and the UK (2020-2034)
Figure 19: Total Diagnosed Prevalent Cases of Hidradenitis Suppurativa in Japan (2020-2034)
Figure 20: Gender-specific Prevalent Cases of Hidradenitis Suppurativa in Japan (2020-2034)
Figure 21: Age-specific Prevalent Cases of Hidradenitis Suppurativa in Japan (2020-2034)
Figure 22: Stage-specific Prevalent Cases of Hidradenitis Suppurativa in Japan (2020-2034)
Figure 23: Total Treated Prevalent Cases of Hidradenitis Suppurativa in Japan (2020-2034)
Figure 24: Window of opportunity in Hidradenitis Suppurativa
Figure 25: HUMIRA's HiSCR response rates through Open-Label Extension (OLE) at Week 168
Figure 26: Total Market Size of Hidradenitis Suppurativa in the 7MM (2020-2034)
Figure 27: Total Market Size of Hidradenitis Suppurativa in the US (2020-2034)
Figure 28: Market size of Hidradenitis Suppurativa by Therapies in the US (2020-2034)
Figure 29: Total Market Size of Hidradenitis Suppurativa in EU4 and the UK (2020-2034)
Figure 30: Market size of Hidradenitis Suppurativa by Therapies in EU4 and the UK (2020-2034)
Figure 31: Total Market Size of Hidradenitis Suppurativa in Japan (2020-2034)
Figure 32: Market size of Hidradenitis Suppurativa by Therapies in Japan (2020-2034)

Executive Summary

Hidradenitis Suppurativa Overview

According to the National Organization of Rare Disorders, HS is a chronic condition characterized by swollen, painful lesions, occurring in the armpit, groin, anal and breast regions. It is painful and long-term skin condition causing abscesses and scarring on the skin. Affected patients may present with acute abscesses, but the condition often progresses to a chronic state with persistent pain, sinus tract fistula formation, and scarring. HS is usually associated with depression and severe overall impairment of quality of life (QoL), exceeding other skin disorders heavily impacting QoL such as psoriasis, atopic dermatitis, alopecia, and acne. HS may restrict simple movements, interfere with routine daily activities, be disfigured because of the wound healing and scarring process, and limit the ability to work.

Pain is reported as the most significant factor contributing to the impairment of QoL in patients with HS, although malodorous and staining secretions also contribute to poor self-perception, embarrassment, stunted social life, and problems with interpersonal relationships. A plethora of comorbidities including inflammatory bowel diseases, spondyloarthropathies, obesity, and metabolic syndrome, may be associated with HS, increasing the disease burden. Therefore, the availability of disease severity assessment tools that might accurately evaluate both clinical picture and patients' discomfort is important for the management of patients with HS and for driving the therapeutic strategy.

Hidradenitis Suppurativa Diagnosis

The diagnosis is primarily clinical, based on symptoms reported by the patient and signs observed by the physician. No pathognomonic test exists, and biopsy is rarely required, especially in well-developed lesions. Primary Diagnosis of HS involves identification of the disease and assessment of its comorbidities. Fulfillment of three criteria are necessary for the diagnosis of HS:


  • Typical lesions: deep-seated, painful nodules
  • Characteristic distribution: Typical anatomical predilection (i.e., axillae, groins, perineal and perianal regions, buttocks, infra-mammary and inter-mammary folds)

Recurrence: Chronicity and recurrence of lesions

Hidradenitis Suppurativa Treatment

It covers the details of conventional and current medical therapies available in the Hidradenitis Suppurativa market for the treatment of the condition. It also provides the country-wise treatment guidelines and algorithm across the United States, Europe and Japan.

The Hidradenitis Suppurativa market report gives a thorough understanding of Hidradenitis Suppurativa by including details such as disease definition, symptoms, causes, pathophysiology, and diagnosis. It also provides Hidradenitis Suppurativa treatment algorithms and treatment guidelines for Hidradenitis Suppurativa in the US, Europe, and Japan.

Hidradenitis Suppurativa Epidemiology

The Hidradenitis Suppurativa epidemiology division provide the insights about historical and current Hidradenitis Suppurativa patient pool and forecasted trend for each seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of The report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

Key Findings

The total diagnosed incident cases of Hidradenitis Suppurativa (HS) patients were found to be more in females than in males in 7MM during the study period i.e. 2017-2030.

The disease epidemiology covered in the report provides historical as well as forecasted Hidradenitis Suppurativa epidemiology [segmented as Total Prevalent Patient Population, Diagnosed Prevalent Patient Population, Age-specific Diagnosed Prevalent Patient Population, Gender-specific Diagnosed Prevalent Patient Population, Stage-Specific (Severity-specific) Prevalent Population, and Treated Prevalent Cases of HS] scenario of Hidradenitis Suppurativa in 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom), and Japan from 2017 to 2030.

Country Wise- Hidradenitis Suppurativa Epidemiology

The epidemiology segment also provides the Hidradenitis Suppurativa epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain and the United Kingdom) and Japan.

Hidradenitis Suppurativa Drug Chapters

Drug chapter segment of the Hidradenitis Suppurativa report encloses the detailed analysis of Hidradenitis Suppurativa marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the Hidradenitis Suppurativa clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.

Hidradenitis Suppurativa Marketed Drugs

Humira: AbbVie

Humira (Adalimumab) is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor (TNF). This drug was created using phage display technology resulting in an antibody with human-derived heavy and light chain variable regions and human IgG1:k constant regions. It is produced by recombinant DNA technology in a mammalian cell expression system and is purified by a process that includes specific viral inactivation and removal steps.

Hidradenitis Suppurativa Emerging Drugs

IFX-1: InflaRx

IFX-1 is a first-in-class monoclonal anti-complement factor C5a antibody, being developed by InflaRx for the treatment of patients with HS. It completely blocks biological activity and demonstrates high selectivity towards its target, C5a, in human blood. Thus, IFX-1 leaves the formation of the membrane attack complex (C5b-9) intact as an important defense mechanism, which is not the case for molecules blocking the cleavage of C5.

Cosentyx (Secukinumab): Novartis Pharmaceuticals

Cosentyx (Secukinumab) is an IL-17A monoclonal antibody that selectively binds to IL-17A and inhibits Interleukin-17A, and IL-17 promotes neutrophil activities and is marketed by Novartis. These cytokines
act on many different cell types and provide defense against different extracellular pathogens causing fungal or bacterial infections.

INCB054707: Incyte Corporation

INCB054707 is a selective JAK1 inhibitor, being developed by Incyte Corporation for the treatment of patients with Moderate-to-severe HS. This therapeutic molecule is administered by an oral route of administration. Currently, the company is investigating this molecule in the Phase II stage of development for HS.

Bimekizumab: UCB Biopharma S.P.R.L

Bimekizumab is the first humanized monoclonal IgG1 antibody that potently and selectively neutralizes both IL-17A and IL-17F, two key cytokines driving inflammatory processes. IL-17A and IL-17F are the most closely related members of the IL-17 family of cytokines.

Bermekimab (MABp1): Janssen Pharmaceutical

MABp1 is a recombinant human IgG1 monoclonal antibody specific for human interleukin-1α, initially being developed by XBiotech for the treatment of patients with HS. Last year Jannsen pharmaceutical acquired rights for this product. It is the only antibody targeting IL-1a currently in clinical development and has the potential for superior efficacy and safety compared to the current standard of care.

Product details in the report.

Hidradenitis Suppurativa Market Outlook

The Hidradenitis Suppurativa market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted Hidradenitis Suppurativa market trends by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.

This segment gives a through detail of Hidradenitis Suppurativa market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria's, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

According to the publisher, Hidradenitis Suppurativa market in the 7MM is expected to change in the study period 2017-2030. The therapeutic market of Hidradenitis Suppurativa in seven major markets is expected to generate USD 798 million in 2017 and will increase in the study period 2017-2030.

Key Findings

This section includes a glimpse of the Hidradenitis Suppurativa market in the 7MM.

The United States Market Outlook

This section provides the total Hidradenitis Suppurativa market Size and market Size by therapies in the United States.

EU-5 Countries: Market Outlook

The total Hidradenitis Suppurativa market Size and market Size by therapies in Germany, France, Italy, Spain and the United Kingdom is provided in this section.

Japan Market Outlook

The total Hidradenitis Suppurativa market Size and market Size by therapies in Japan is also mentioned.

Hidradenitis Suppurativa Drugs Uptake

This section focuses on the rate of uptake of the potential drugs recently launched in the Hidradenitis Suppurativa market or expected to get launched in the market during the study period 2017-2030. The analysis covers Hidradenitis Suppurativa market uptake by drugs; patient uptake by therapies; and sales of each drug.

This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and Size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Hidradenitis Suppurativa Pipeline Development Activities

The report provides insights into different therapeutic candidates in Phase II, and Phase III stage. It also analyses Hidradenitis Suppurativa key players involved in developing targeted therapeutics.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing and patent details for Hidradenitis Suppurativa emerging therapies.

Reimbursement Scenario in Hidradenitis Suppurativa

Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In report we take reimbursement into consideration to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.

KOL - Views

To keep up with current market trends, we take KOLs and SME's opinion working in Hidradenitis Suppurativa domain through primary research to fill the data gaps and validate our secondary research. Their opinion helps to understand and validate current and emerging therapies treatment patterns or Hidradenitis Suppurativa market trend. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the market and the unmet needs.

Competitive Intelligence Analysis

The publisher performs Competitive & Market Intelligence analysis of the Hidradenitis Suppurativa Market by using various Competitive Intelligence tools that includes - SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies etc. The inclusion of the analysis entirely depends upon the data availability.


Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Incyte Corporation
  • ACELYRIN
  • AbbVie
  • MoonLake Immunotherapeutics
  • Boehringer Ingelheim
  • Priovant Therapeutics
  • Eli Lilly
  • Incyte Corporation
  • Sanofi
  • Kymera Therapeutics
  • UNION Therapeutics