Applications of Modern Mass Spectrometry covers the latest advances in the use of mass spectrometry in scientific research. The series attempts to present readers' information on the broad range of mass spectrometry techniques and configurations, data analysis, and practical applications.
Each volume contains contributions from eminent researchers who present their findings in an easy to read format. The multidisciplinary nature of the works presented in each volume of this book series makes it a valuable reference on mass spectrometry to academic researchers and industrial R&D specialists in applied sciences, biochemistry, life sciences, and allied fields.
The first volume of the series presents 5 reviews:
- Applications of mass spectrometry for the determination of the microbial crude protein synthesis in ruminants
- Qualitative and quantitative LC-MS analysis in food proteins and peptides
- Chemometrics is a powerful and complementary tool for mass spectrometry applications in life sciences
- Recent developments of allied techniques of qualitative analysis of heavy metal ions in aqueous solutions with special reference to modern mass spectrometry
- New techniques and methods in explosive analysis
Table of Contents
Chapter 1 Applications of Mass Spectrometry for the Determination Of Microbial Crude Protein Synthesis in Ruminants
- Lizbeth E. Robles-Jimenez, Ivan Mendez Martinez, Joaquim Balcells and Manuel Gonzalez-Ronquillo
- Introduction
- Microbial Crude Protein Synthesis
- Dietary Nitrogen Fractions and Their Potential Use by Ruminants
- Methods of Directly and Indirectly Estimating Microbial Protein
- Synthesis
- Characteristics and Uses of 15N
- Common Uses of 15N
- 15N-Labelled Forage
- Ammonium Sulfate & Ammonium Chloride
- Omasal Sampling and Analysis
- Ruminal and Duodenal Samples
- Liquid-Associated and Solid-Associated Microbes in the Rumen
- Endogenous Excretion of Purine Derivatives
- Extraction of Purine Bases and Derivatives
- Extraction of Allantoin Or Allantoic Acid
- Isotope Abundance
- Rumen 15N Pool Sizes in Excess of Background Levels
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 2 Qualitative and Quantitative Lc-Ms Analysis in Food Proteins and Peptides
- Yi-Shen Zhu, Zhonghong Li and Lulu Zhao
- Introduction
- Qualitative Mehtods of Lc-Ms on Food Proteins and Peptides
- The Primary Structure and Relative Molecular Mass of Proteins and Peptides
- Intramolecular Disulfide Bonds Analysis of Proteins
- Structural Analysis of Ptms Proteins and Peptides
- Quantitative Methods of Lc-Ms on Food Proteins and Peptides
- Labeled Quantitation Methods
- Chemical Labeling Method
- Sulfhydryl Labeling Method
- Carboxyl Labeling Method
- Metabolic Labeling Method
- 15N/14N Labeling Technology
- Silac Technology
- Enzymatic Labeling Method
- Application of 18O Labeling Method in Food Protein Research
- Introduction of Multiple Reaction Monitoring (Mrm)
- Application of Mrm in Proteins and Peptides Research
- Label-Free Quantitation Method
- Application of Label-Free Quantitation Method in Food Protein Research
- Comparison of Two Approaches of Label-Free Quantitation Method
- Comparison Between Labeled Quantitation and Label-Free Quantitation Methods
- Outlook
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 3 Chemometrics As a Powerful and Complementary Tool For Mass Spectrometry Applications in Life Sciences
- Yahya Izadmanesh and Jahan B. Ghasemi
- Introduction
- Mass Spectrometry Omics Data
- Metabolomic Mass Data
- Experimental Design
- Data Preprocessing
- Noise Filtering and Baseline Correction
- Peak Detection and Deconvolution
- Normalization
- Metabolites Identification
- Resolution Algorithms
- Variable Selection
- Variable Ranking
- Variable Subset Selection
- Modeling of the Data
- Unsupervised Methods
- Supervised Methods
- Non-Linear Methods
- Model Optimization and Validation
- Proteomic Mass Data
- Genomics Mass Data
- Mass Spectrometry Imaging
- Data Pretreatment and Exploration
- Data Compression
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 4 Recent Developments of Allied Techniques of Qualitative Analysis of Heavy Metal Ions in Aqueous Solutions with Special Reference to Modern Mass Spectrometry
- Bijoy Sankar Boruah and Rajib Biswas
- Introduction
- Techniques for Sensing Heavy Metal Ion
- Colorimetric Technique
- Optical Fiber Technique
- Electrochemical Method
- Mass Spectrometry
- Future Direction
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
Chapter 5 New Techniques and Methods in Explosive Analysis Beril Anilanmert and Salih Cengiz
- Introduction
- A Concise Information on Explosives
- The Sample Treatment and Detection Techniques for Explosive
- Analysis in the Literature
- Mass Spectrometric Techniques Used in Explosive Analysis
- Analysis with Gc-Ms & Gc-Ms/Ms
- Analysis with Lc-Ms & Lc-Ms/Ms
- Use of Triple Quadrupole Ms and Hyphenated Instruments with Tof-Ms, Ion Trap
- And Orbitrap
- Direct Analysis Techniques
- Ambient Ms (Dart-Ms, Desi-Ms, and Similar Techniques) and Hyphenation of Ion
- Mobility and Ir Techniques with Ms
- On-Site Detection
- Results
- The Current Needs & Future Prospects
- List of Abbreviations
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Subject Index
Samples
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Author
- Atta-ur-Rahman
- M. Iqbal Choudhary
- Syed Ghulam Musharraf
