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Pharmaceutical Polymers 2007: Basel, Switzerland, 20-21 June 2007 - Conference Proceedings


Description: Polymer suppliers are continuously striving to produce cleaner materials with more precise specifications and increased functionality. The key, it seems, is to develop a product with a significant processing advantage to satisfy pharmaceutical formulators in scale-up. Variations in particle size, amorphousness and crystallisation can make a world of difference to the quality of a pharmaceutical polymer and, ultimately, its ability to effectively control the release of a drug.

We held our first international conference on Pharmaceutical Polymers on 20-21 June 2007 in Basel, which brought together world experts to discuss the latest techniques for the process optimisation of pharmaceutical polymers.


Contents: SESSION 1. HOT MELTING PROCESSING OF PHARMACEUITICAL SYSTEMS
Paper 1 The characterisation of solid dispersions formed via a hot-melt extrusion
G.P. Andrews, D.S. Jones & O. Abadu Diak, Queens University Belfast, UK

Paper 2 Physiochemical and drug release characteristics of Quinine and polymers prepared by hot-melt extrusion
Daniel Margetson, GlaxoSmithKline, UK

Paper 3 Hot runner systems improving injection moulding processes
Dipl Ing Hilmar Heithorst, GÜNTHER Heisskanaltechnik, GmbH, Germany

Paper 4 Polymer processing techniques for the pharmaceuitical field
Simone Maccagnan, Gimac di Maccagnan Giorgio, Italy

Paper 5 Processing silicone polymers: a foundation to creating consistent silicone systems
Marie Ange Roux, NuSil Technology, France

SESSION 2. PROCESSING OF POLYMERS FOR SOLID DOSAGE FORM APPLICATION

Paper 6 Applications of ethylcellulose polymers on extended release oral solid dosage forms
Dr. Ali R. Rajabi-Siahboomi, Colorcon, Inc, USA

Paper 7 Rheological evaluation of extrusion / spheronisation processing
Ross McGlashan, Neil MacPhail, Ian j.Hardy & Shaun Fitzpatrick, Merc Sharp & Dohme, UK

Paper 8 Fluidised hot melt granulation as a novel pharmaceuitical granulation process
Dr. G.P Andrews , Queens University Belfast, UK

SESSION 3. INDUSTRIAL ISSUES CONCERNING PROCESSING PHARMACEUITICAL POLYMERSS

Paper 9 Influence of processing parameters on regulatory compliance of pharma devices
Daniel Behrens, Ticona GmbH, Germany

Paper 10 Efficient use of polyolefins in medical devices and pharmaceutical packaging
Dr. Michael Luetke, Basell Polyolefins, Germany

Paper 11 How to ensure development time with low risk on changes
Marc Dietlin, Invibio, France

Paper 12 Leachables and extractables testing of polymer device components
Keith Scott, Rapra Technology, UK

SESSION 4. PHARMACEUTICAL POLYMERS IN DRUG DELIVERY AND RELATED ISSUES

Paper 13 Structure-property relationships in poly (lactide-co-glycolide): impact on polymer behaviour in controlled drug delivery systems
Dr. Liz Meehan, AstraZeneca, UK

Paper 14 Multiblock copolymers of PEG/PPG-synthesis, properties and potential pharmaceutical use
Nadejda V Tabakova, Svoboda V Tabakova & Vera V Mircheva, Bulgarian Academy Of Sciences, Bulgaria

Paper 15 Smart drug delivery capsule design using shape memory alloy polymers and bio-materials
Venkataramanan Soundararajan, Massachusetts Institute of Technology (MIT), USA & Shamit Shrivastava, Indian Institute of Technology, India

Paper 16 The use of PLGA as an excipient for parental depot formulations
Dr. Holger Petersen, Novartis Pharma AG, Switzerland

Paper 17 Performance of hypromellose matrices in hydro-alcoholic material
Ali R. Rajabi-Siahboomi & Marina Levina , Colorcon, Inc, USA

Paper 18 Drug loaded biomicrodwarfs using a novel biopolymeric material from Arachis hypogea sedds
Dr. N.V Satheesh Madhav, Pharmacy College, India




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