Radiotherapy is now one of the major cancer treatments. The field of accelerator and medical physics is important and growing to support high precision cancer radiotherapy. Advances in Accelerators and Medical Physics provides in-depth and comprehensive coverage of the basic concepts in x-ray therapy, electron beam therapy, particle therapy, boron neutron capture therapy, and molecular imaging and therapy. Novel technologies such as FLASH therapy and laser ion accelerator are also introduced. Each section of the book presents the current state of accelerators, irradiation methods and therapy technologies, as well as future trends in advanced research. This book will serve as a key resource for researchers and students to find all information on latest cancer radiotherapy technologies and methods.
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Table of Contents
SECTION A X-ray therapy and electron beam therapy1. Electron accelerator and beam irradiation system
2. External beam radiation therapy
3. Immobilization and patient positioning
4. Respiratory motion management
5. Radiation treatment planning (photon and electron beam therapy)
6. Dosimetric verification
7. Adaptive radiotherapy
SECTION B Particle therapy
8. Proton cyclotron accelerator and line scanning irradiation system
9. Proton synchrotron accelerator and spot scanning irradiation system
10. Carbon-ion synchrotron accelerator and raster scanning irradiation system
11. Quantum scalpel
12. Irradiation and therapy methods
13. Management of patient position and respiratory motion
14. Treatment planning
15. Dosimetric verification
16. Radiation protection
SECTION C Boron neutron capture therapy (BNCT)
17. Principle and current status
18. Proton linear accelerator and lithium target system
19. Proton linear accelerator and beryllium target system
20. Proton cyclotron accelerator and beryllium target system
21. Irradiation method and the immobilization and positioning of patients (head and neck)
22. Therapy method, irradiation method, and immobilization and positioning of patients (brain)
23. Therapy method, irradiation method, and immobilization and positioning (skin)
24. Treatment planning
25. Dosimetric verification
26. Future works
SECTION D Molecular imaging and therapy
27. Electron linear accelerator for medical radionuclide production
28. Cyclotron accelerators for the production of medical radionuclides
29. Dosimetry in therapy using radiopharmaceuticals
SECTION E Novel technologies
30. FLASH radiotherapy
31. Laser-driven ion accelerator
Authors
Toshiyuki Shirai Director, Department of Accelerator and Medical Physics, Institute for Quantum Medical Science, National Institute for Quantum Science and Technology, Chiba, Japan. Dr. Toshiyuki Shirai is the Director of the Department of Accelerator and Medical Physics at the National Institutes for Quantum and Radiological Science and Technology (QST). He received his PhD degree from the Faculty of Science, Kyoto University. After graduation, he worked in the accelerator and beam physics at the Institute for Chemical Research, Kyoto University. At QST, his research interests are in medical physics and medical accelerators for particle therapy, especially carbon-ion radiotherapy. He has served as a Councilor of the Particle Accelerator Society of Japan. Teiji Nishio Professor and Director of the Medical Physics Laboratory, Division of Health Science, Graduate School of Medicine, Osaka University, Osaka, Japan.. Dr. Teiji Nishio is Professor and Director of the Medical Physics Laboratory, Division of Health Science, Graduate School of Medicine, Osaka University, Osaka, Japan. He received his Ph.D. in Science from the Department of Physics, Graduate School of Science, Rikkyo University for his research in nuclear astrophysics. He also received his Ph.D. in Medicine from the Department of Biophysics and Medicine, Graduate School of Medicine, The University of Tokyo for his research in medical physics. So far, he has been working on research and development of proton therapy, especially, Beam On-Line PET system, which visualize the proton irradiation area, at the National Cancer Center Japan. He is currently engaged in research and education on X-ray therapy, proton therapy, and heavy particle therapy in the Medical Physics Laboratory at Osaka University. He is also a board member of the Japan Society of Medical Physics (JSMP). Kiyokazu Sato Senior Consultant, Keihin Product Operations, Toshiba Energy Systems & Solutions Co., Kanagawa, Japan. Kiyokazu Sato is the Senior Consultant of Keihin Product Operations Toshiba Energy Systems & Solutions Corporation. He is responsible for improving technologies and the quality of Keihin Product Operations which is the core factory in Toshiba for energy related equipments such as steam and hydro turbines, turbine-generators, heat exchangers, nuclear reactor internals and new energy equipment. Prior to his current role, he was the Senior Manager of Machinery and Equipment Department and in charge of designing and fabricating new energy equipment such as particle accelerators, superconducting magnets, equipment for fusion reactors, and special remote handling systems.Dr. Sato holds a PhD in Engineering for his work on heavy ion linear accelerators from Tokyo Institute of Technology, Tokyo, Japan.
