*Association of American Publishers (AAP) PROSE Award Finalist in Biomedicine and Neuroscience, 2024* Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment, Stem cell therapy for osteoarthritis, hPSC-derived RPE transplantation for the treatment of macular degeneration, and much more.
The book provides not only fundamental aspects and cultural and production methods of stem cells, but also the critical engineering aspects of stem cells such as drug screening using hepatocytes and disease treatment by transplantation of retinal pigment epithelium and cardiomyocytes which are derived from human pluripotent stem cells.
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Table of Contents
PrefaceAkon Higuchi, Yinghong Zhou and Shih-Hwa Chiou
- Introduction to stem cells
Zeyu Tian, Tao Yu, Jun Liu, Ting Wang, and Akon Higuchi
- Engineered adult stem cells: current clinical trials status of disease treatment
Pingping Han, Corey Stephan Moran, Chun Liu, Rebecca Griffiths, Yinghong Zhou, and
Saso Ivanovski
- Xeno-free culture and proliferation of hPSCs on 2D biomaterials
Ting Wang, Tao Yu, Chang-Yen Tsai, Zhao-Yu Hong, Wen-Hui Chao, Yi-Shuo Su, Suresh Kumar Subbiah, Remya Rajan Renuka, Shih-Tien Hsu, Gwo-Jang Wu, and Akon Higuchi
- Stem cell culture and differentiation in 3-D scaffolds
Yasuhiko Tabata, Idaszek Joanna, and Akon Higuchi
- Current trends and promising clinical utility of IPSC-derived MSC (iMSC)
Shih-Hwa Chiou, Alan Han Kiat Ong , Shih-Jie Chou, Ahmed Faris Aldoghachi, Jit Kai Loh, Nalini Devi Verusingam,
Yi-Ping Yang, and Yueh Chien
- Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells
Saeko Akiyama, Noriaki Saku, Shoko Miyata, Kenta Ite, Hidenori Nonaka, Masashi Toyoda, Akihide Kamiya, Tohru Kiyono, Tohru Kimura, Mureo Kasahara, and Akihiro Umezawa
- Cardiac cell sheet engineering for regenerative medicine and tissue modeling
Katsuhisa Matsuura and Tatsuya Shimizu
- Mesenchymal stem cells in osteoarthritis: The need for translation into clinical therapy
Feng Gao, Xinzhan Mao, and Xiaoxin Wu
- hPSC-derived RPE transplantation for the treatment of macular degeneration
Qian Liu, Jun Liu, and Akon Higuchi
- Universal and hypoimmunogenic pluripotent stem cells for clinical usage
Tzu-Cheng Sung, Kailibinuer Maitiruze, Jiandong Pan,
Jian Gong, Yongheng Bai, Xiaodong Pan, and Akon Higuchi
- Clinical Usage of Dental Stem Cells and Their Derived Extracellular Vesicles
Yinghong Zhou, Tian Xu, Cong Wang, Pingping Han, and Saso Ivanovski
- Vascularization of cutaneous wounds by stem cells
Motaharesadat Hosseini and Abbas Shafiee
- Application of IPSC and M?ller glia derivatives in retinal degenerative diseases
Guoge Han, Pinghui Wei, and Quanhong Han
- Pluripotent Stem Cells as a Therapy for Type 1 Diabetes
Bernard E. Tuch, Iris S. Cheng, Hoang Phuc Dang, Hui Chen, and Tim R. Dargaville
- Stem cell challenges and opportunities
Kenta Ite, Masashi Toyoda, Saeko Akiyama, Shin Enosawa, Saeko Yoshioka,
Takaaki Yukitake, Mayu Yamazaki-Inoue, Kuniko Tatsumi, Hidenori Akutsu, Hiroshi Nishina, Toru Kimura, Naoko Otani, Atsuko Nakazawa, Akinari Fukuda, Mureo Kasahara, and Akihiro Umezawa
