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European Non-Hodgkin's Lymphoma Therapeutics Markets
Frost & Sullivan, December 2007, Pages: 63
This Frost & Sullivan research service titled European Non-Hodgkin’s Lymphoma Therapeutics Markets provides drivers, restraints and revenue forecasts for this market. In this research, Frost & Sullivan's expert analysts thoroughly examine the following markets: chemotherapy and targeted therapies.
Market Overview
High Unmet Need Creates Opportunity for Novel NHL Drugs
It is estimated that about 1.75 million people worldwide are living with non-Hodgkin’s lymphoma (NHL). The risk of developing the disease increases with age, especially among the 55-75 age group. Moreover, with life expectancy levels rising across Europe, the demand for NHL drugs is set to grow. Accordingly, the European NHL therapeutics markets are set to expand from an estimated $2.2 billion in 2006 to almost $7.2 billion in 2013. NHL is a complicated disease with about 25-30 sub types. Clinical trials required for each indication makes the entry of novel drugs difficult. At present, the market is monopolised by MabThera. Although CHOP chemotherapy is the major treatment for all forms of NHL, it is highly genericised with limited prospects for revenue growth.
"The relapsing nature of NHL is impelling the need for new therapeutic options," notes the analyst of this research. "Though MabThera is very popular and has gained widespread acceptance, there still exists a high unmet need among NHL patients." Market dynamics are poised to change in the near future with the anticipated launch of many promising pipeline drugs currently in phase 3 of development. However, most research-based biotechnology firms are currently battling significant losses. Moreover, stringent clinical and regulatory hurdles could curb potential returns from biotechnology products. For such companies, difficulties in securing resources to fund clinical trials will delay the development process and extend the time to market.
Strategy of Developing Add-on Drugs Likely to Gain Success
MabThera is projected to retain its market leadership position over the next 5-6 years. Most drugs in the pipeline are being positioned as add-on combination therapies with MabThera or CHOP. The market is poised to accelerate from 2012 onwards, pushed by the numerous promising drugs currently in phase 3 development stage. Add-on drugs, in combination with the current market leader MabThera or chemotherapy, is a prospective market driver. For instance, Favrille is pinning its hopes on Favid being a block buster when approved for commercialisation.
Most oncologists are satisfied with MabThera and may not replace it with newer alternatives. Hence, combination drugs with MabThera or CHOP would gain easier acceptance among oncologists and patients. "Big pharma should look for strategic alliances or acquisition of promising pipeline drugs," advises the analyst. "Small-sized biotechnology companies should focus on research and finding a suitable marketing partner."
-1. Executive Summary
--1. Overview
---1. Overview of European Non-Hodgkin's Lymphoma Therapeutics Market
-2. Glossary of Terms
--1. List of Terms
---1. Abbreviations
-3. Research Methodology
--1. Research Scope and Objective
---1. Methodology
-4. Market Overview
--1. Introduction
---1. Disease Characteristics
---2. Epidemiology
---3. Risk Factors
---4. Symptoms
---5. Classification and Staging
---6. Major Sub Types
---7. Current Treatment Regimes
-5. Industry Challenges
--1. Industry Challenges for the European Non-Hodgkin's Lymphoma Therapeutics Market
---1. Challenges Faced by Pharmaceutical and Biotechnology Companies
-6. Total European Market for Non-Hodgkin's Lymphoma Therapeutics Market
--1. Market Drivers and Restraints
---1. Market Drivers
---2. Market Restraints
---3. Market Engineering Measurement Analysis
-7. Total Forecasts for the European Non-Hodgkin's Therapeutics Market
--1. Forecasts and Pipeline Analysis
---1. Patient Forecasts
---2. Revenue Forecasts
---3. Market Share Analysis
---4. Pipeline Analysis
-8. Strategic Recommendations for the European Non-Hodgkin's Therapeutics Market
--1. Market Engineering Recommendations
---1. Strategic Recommendations
-9. Database of Key Industry Participants
--1. Key Industry Participants
---1. Key Participants in the Non-Hodgkin's Lymphoma Market
-10. Decision Support Databases
--1. Databases for Analysis
---1. Number of Biotechnology Companies
---2. Private Investment in Biotechnology
---3. Government R&D Investment in Biotechnology
---4. Per cent of Government Investment in Biotechnology
---5. Number of Biotechnology Patents Filed at or Granted by the European Patent Office
---6. Number of Biotechnology Patents Granted by the US Patent & Trademark Office
List of Figures
Chapter 5
Total Non-Hodgkin's Lymphoma Therapeutics Market: Impact of Top Industry Challenges (Europe), 2007-2013
Chapter 6
Total Non-Hodgkin's Lymphoma Therapeutics Market: Market Drivers Ranked in Order of Impact (Europe), 2007-2013
Total Non-Hodgkin's Lymphoma Therapeutics Market: Market Restraints Ranked in Order of Impact (Europe), 2007-2013
Chapter 7
Total Non-Hodgkin's Lymphoma Therapeutics Market: Incidence and Mortality (Europe), 2003-2013
Total Non-Hodgkin's Lymphoma Therapeutics Market: Revenue Forecasts (Europe), 2003-2013
Chapter 10
Decision Support Database: Number of Biotechnology Companies (World), 1999-2006
Decision Support Database: Private Investment in Biotechnology in Million USD (World), 1999-2006
Decision Support Database: Government R&D Investment in Biotechnology in Million USD (World), 1999-2006
Decision Support Database: Per cent of Government Biotechnology Investment (World), 1999-2006
Decision Support Database: Number of Biotechnology Patents Filed at Granted by the European Patent Office (World), 1996-2000
Decision Support Database: Number of Biotech Patents granted by US Patent & Trademark Office (World), 1996-2000
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