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Organic Syntheses, Volume 99. Edition No. 1

  • Book

  • 448 Pages
  • June 2023
  • John Wiley and Sons Ltd
  • ID: 5841821
The current volume continues the tradition of the Organic Syntheses series, providing carefully checked and edited experimental procedures that describe important synthetic methods, transformations, reagents, and synthetic building blocks or intermediates with demonstrated utility in organic synthesis. These significant and interesting procedures should prove worthwhile to many synthetic chemists working in increasingly diverse areas. A trusted guide for professionals in organic and medicinal chemistry in academia, government, and industries, including pharmaceuticals, fine chemicals, agrochemicals, and biotechnological products.

Table of Contents

Chapter 1 Synthesis of [(R)-DTBM-SEGPHOS]NiCl2 for the Enantioselective Acetal Formation from N-Propanoyl-1,3-Thiazinane-2-thione and Trimethyl Orthoformate

Chapter 2 Synthesis of Alkylboronic Esters from Alkyl Iodides

Chapter 3 Preparation of N-Formylamides by Oxidative Cleavage of N-Acylaminoacids

Chapter 4 Transition-Metal-Free Synthesis of an Aryl Boronate Ester through Base-Mediated Boryl Substitution of an Aryl Halide with a Silylborane

Chapter 5 A Convenient Method for the Removal of Tetrabutylammonium Salts from Desilylation Reactions

Chapter 6 Discussion Addendum for: Asymmetric Michael Reaction of Aldehydes and Nitroalkenes

Chapter 7 Preparation of a Donor-Acceptor Stenhouse Adduct (DASA): 5-((2Z,4E)-5-(Diethylamino)-2-hydroxypenta-2,4-dien-1-ylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione

Chapter 8 Preparation of MIDA Anhydride and Reaction with Boronic Acids

Chapter 9 Discussion Addendum for: Preparation of 1,1-Difluoroallenes by Difluorovinylidenation of Carbonyl Compounds

Chapter 10 Ethoxypillar[6]arene

Chapter 11 Organocatalytic Dimerization of Succinaldehyde

Chapter 12 Synthesis of Phenanthridinones via the Palladium-Catalyzed Annulation of Benzyne

Chapter 13 Synthesis of Triphenylene via the Palladium-Catalyzed Annulation of Benzyne

Chapter 14 Synthesis of (((1R,3S,3′S)-3,3′-Diethyl-3H,3′H-1,1′-spirobi[isobenzofuran]-7,7′-diyl)bis(oxy))bis(diphenylphosphane)

Chapter 15 Discussion Addendum for: Nickel-Catalyzed Cross-Coupling of Aryl Halides with Alkyl Halides: Ethyl 4-(4-(4-methylphenylsulfonamido)-phenyl)butanoate

Chapter 16 Discussion Addendum for: Detrifluoroacetylative Diazo Group Transfer: (E)-1-Diazo-4-phenyl-3-buten-2-one

Chapter 17 Preparation of 9-Azabicyclo[3.3.1]nonane-N-oxyl (ABNO)

Chapter 18 Discussion Addendum for: Synthesis of N-Boc-N-Hydroxymethyl-L-phenylalaninal and Methyl trans-Oxazolidine-5-carboxylate, Chiral Synthons for threo-β-Amino-α-hydroxy Acids

Chapter 19 Large Scale Oxidative Cyclization of (E)-Hex-3-en-1-yl(4-Methoxyphenyl)sulfamate

Chapter 20 Synthesis of Carboxylic Acids from Benzamide Precursors Using Nickel Catalysis

Chapter 21 Stereoselective Synthesis of Dimethyl 4(S)-Allyl-N-Boc-L-glutamate and Related Congeners

Chapter 22 Discussion Addendum for: Preparation of Diisopropylammonium Bis(catecholato)cyclohexylsilicate

Chapter 23 Preparation of 1,2:5,6-Di-O-cyclohexylidene-D-mannitol and 2,3-Cyclohexylidene-D-glyceraldehyde

Chapter 24 Transformation of a N,N-Dimethylaniline N-oxide into a Tetrahydroquinoline Scaffold via a Formal Polonovski-Povarov Reaction

Index

Authors

Richmond Sarpong