Contents:

TABLE OF CONTENTS LIST OF EXHIBITS EXECUTIVE SUMMARY METHODOLOGY 1.0 THE HUMAN SPINE 1.1 Anatomy of the Human Spine 1.2 Degenerative Spinal Disorders 1.3 Deformity Spinal Disorders 1.4 Trauma/Tumor Spinal Disorders 1.5 Treatment Options 1.6 Spinal Fusion 2.0 BRAZILIAN SPINAL IMPLANT MARKET 2.1 Market Overview 2.2 Country Overview 2.2.1 Demographics & Economy 2.2.2 Health Care Environment 2.3 Market Analysis 2.3.1 Procedures 2.3.2 Market Forecast 2.3.3 Market Drivers and Limiters 2.4 Competitive Analysis 3.0 TRADITIONAL THORACOLUMBAR IMPLANT MARKET 3.1 Market Overview 3.2 Background Device Information 3.3 Market Analysis 3.3.1 Procedures 3.3.2 Market Forecast 4.0 TRADITIONAL CERVICAL IMPLANT MARKET 4.1 Market Overview 4.2 Background Device Information 4.3 Market Analysis 4.3.1 Procedures 4.3.2 Market Forecast 5.0 INTERBODY DEVICE MARKET 5.1 Market Overview 5.2 Background Device Information 5.2.2 Implant Material 5.2.3 Surgical Approach 5.3 Market Analysis 5.3.1 Procedures 5.3.2 Market Forecast 6.0 NONFUSION IMPLANT MARKET 6.1 Market Overview 6.2 Background Device Information 6.2.1 Artificial Disc Overview 6.2.2 Dynamic Stabilization Overview 6.2.3 Nuclear Disc Prosthesis Overview 6.3 Market Analysis 6.3.1 Procedures 6.3.2 Market Forecast APPENDIX A: MRG ACRONYMS AND INITIALISMS List of Exhibits EXECUTIVE SUMMARY Exhibit ES-1: Spinal Implant Market, by Segment, Brazil (US$), 2004-2010 Exhibit ES-2: Spinal Implant Market, by Market, 2005 Exhibit ES-3: Traditional Thoracolumbar Market, by Segment, Brazil (US$), 2004-2010 Exhibit ES-4: Traditional Cervical Market, by Segment, Brazil (US$), 2004- 2010 Exhibit ES-5: IBD Market, by Segment, Brazil (US$), 2004-2010 Exhibit ES-6: Nonfusion Market, by Segment, Brazil (US$), 2004-2010 Exhibit ES-7: Leading Competitors in the Spinal Implant Market, Brazil, 2005 METHODOLOGY Exhibit M-1: Currency Exchange Rates, 2005 CHAPTER 1: THE HUMAN SPINE Exhibit 1-1: Human Spine, Lateral View Exhibit 1-2: The Vertebral Bodies and Vertebral Discs of the Spine Exhibit 1-3: Function of the Spinal Column Exhibit 1-4: Instrumented Spinal Fusion Procedure Classification CHAPTER 2: BRAZILIAN SPINAL IMPLANT MARKET Exhibit 2-1: Spinal Implant Market, As a % of Total, Brazil (US$), 2004-2010 Exhibit 2-2: Country Statistics, Brazil Exhibit 2-3: Health Care Statistics, Brazil Exhibit 2-4: Instrumented Spinal Procedures, by Segment, Brazil, 2004- 2010 Exhibit 2-5: Instrumented Spinal Procedures, by Segment, as a % of Total, Brazil, 2004-2010 Exhibit 2-6: Instrumented Spinal Procedures, by Sector, Brazil, 2005 Exhibit 2-7: Instrumented Spinal Procedures, by Type and Sector, Brazil, 2005 Exhibit 2-8: Spinal Implant Market, by Segment, Brazil (US$ and R$), 2004- 2010 Exhibit 2-9: Spinal Implant Market, by Segment and as a % of Total, Brazil, 2005 Exhibit 2-10: Spinal Implant Market, by Sector, Brazil, 2005 (Tabular Format) Exhibit 2-11: Spinal Implant Market, by Sector, Brazil, 2005 (Graphical Format) Exhibit 2-12: Drivers of the Spinal Implant Market, Brazil Exhibit 2-13: Over-65 cohort, Brazil, 2000-2050 (Tabular format) Exhibit 2-14: Over-65, as a % of the Total Population, Brazil, 2000-2050 (Graphical format) Exhibit 2-15: Limiters of the Spinal Implant Market, Brazil Exhibit 2-16: Leading Competitors in Spinal Implant Market, Brazil, 2005 CHAPTER 3: TRADITIONAL THORACOLUMBAR IMPLANT MARKET Exhibit 3-1: Traditional Thoracolumbar Implant Market, Brazil (US$), 2004- 2010 Exhibit 3-2: Select Thoracolumbar Pedicle Screw Systems, by Company, 2005 Exhibit 3-3: Instrumented Thoracolumbar Fusion Procedures, by Instrumentation, Brazil, 2004-2010 Exhibit 3-4: Traditional Thoracolumbar Fusion Procedures, by Pathology, Brazil, 2004-2010 (Tabular Format) Exhibit 3-5: Traditional Thoracolumbar Fusion Procedures, by Pathology, Brazil, 2004-2010 (Graphical Format) Exhibit 3-6: Instrumented Thoracolumbar Fusion Procedures, by Sector, Brazil, 2005 Exhibit 3-7: Traditional Thoracolumbar Fusion Procedures, by Sector, Brazil, 2005 Exhibit 3-8: Traditional Thoracolumbar Implant Market, by Pathology, Brazil (US$), 2004-2010 (Tabular Format) Exhibit 3-9: Traditional Thoracolumbar Implant Market, by Pathology, Brazil (R$), 2004-2010 Exhibit 3-10: Traditional Thoracolumbar Implant Market Growth, by Pathology, Brazil, 2005-2010 Exhibit 3-11: Traditional Thoracolumbar Implant Market, by Pathology, Brazil (US$), 2004-2010 (Graphical Format) Exhibit 3-12: Traditional Thoracolumbar Implant Market, by Sector, Brazil (US$), 2005 Exhibit 3-13: Traditional Thoracolumbar Implant Market, by Sector, Brazil (R$), 2005 CHAPTER 4: TRADITIONAL CERVICAL IMPLANT MARKET Exhibit 4-1: Traditional Cervical Implant Market, by Segment, Brazil (US$), 2005 Exhibit 4-2: Select Anterior Cervical Fusion Systems, by Design, 2005 Exhibit 4-3: Instrumented Cervical Fusion Procedures, by Instrumentation, Brazil, 2004-2010 Exhibit 4-4: Traditional Cervical Fusion Procedures, by Approach, Brazil, 2004-2010 (Tabular Format) Exhibit 4-5: Traditional Cervical Fusion Procedures, by Approach, Brazil, 2004-2010 (Graphical Format) Exhibit 4-6: Instrumented Cervical Fusion Procedures, by Sector, Brazil, 2005 Exhibit 4-7: Traditional Cervical Fusion Procedures, by Sector, Brazil, 2005 Exhibit 4-8: Traditional Cervical Implant Market, by Approach, Brazil (US$), 2004-2010 (Tabular Format) Exhibit 4-9: Traditional Cervical Implant Market, by Approach, Brazil (R$), 2004-2010 Exhibit 4-10: Traditional Cervical Implant Market Growth, by Approach, Brazil, 2005-2010 Exhibit 4-11: Traditional Cervical Implant Market, by Approach, Brazil (US$), 2004-2010 (Graphical Format) Exhibit 4-12: Traditional Cervical Implant Market, by Sector, Brazil (US$), 2005 Exhibit 4-13: Traditional Cervical Implant Market, by Sector, Brazil (R$), 2005 CHAPTER 5: INTERBODY DEVICE MARKET Exhibit 5-1: IBD Device Market, by Segment, Brazil, 2005 Exhibit 5-2: IBD Classification Exhibit 5-3: Selected Nonbone Interbody Fusion Devices, 2005 Exhibit 5-4: IBD Procedures, by Type, Brazil, 2005 Exhibit 5-5: IBD Procedures, by Region of the Spine, Brazil, 2004-2010 Exhibit 5-6: Lumbar IBD Procedures, by Device, Brazil, 2004-2010 (Tabular Format) Exhibit 5-7: Lumbar IBD Procedures, by Device, as a % of Total, Brazil, 2004-2010 (Graphical Format) Exhibit 5-8: IBD Fusion Procedures, by Sector, Brazil, 2005 Exhibit 5-9: IBD Market, by Device, Brazil (US$), 2004-2010 Exhibit 5-10: IBD Market, by Device, Brazil (R$), 2004-2010 Exhibit 5-11: IBD Market Growth, by Device, Brazil, 2005-2010 Exhibit 5-12: IBD Market Value, by Device, as a % of Total, Brazil (US$), 2005 Exhibit 5-13: IBD Market, by Sector, Brazil (US$), 2005 Exhibit 5-14: IBD, by Sector, Brazil (R$), 2005 CHAPTER 6: NONFUSION IMPLANT MARKET Exhibit 6-1: Nonfusion Implant Market, by Segment, Brazil (US$), 2005 Exhibit 6-2: Primary Objectives of AD Replacement Exhibit 6-3: General Contraindications of AD Replacement Exhibit 6-4: Selected Mergers and Acquisitions in the AD Market, 2002-2005 Exhibit 6-5: Nonfusion Procedures, by Device, Brazil, 2004-2010 Exhibit 6-6: Nonfusion Procedures, by Sector, Brazil, 2005 Exhibit 6-7: ASP Comparison of Spinal Implants, by Implant Type, Brazil, 2005 Exhibit 6-8: Nonfusion Market, by Device, Brazil (US$), 2004-2010 Exhibit 6-9: Nonfusion Market, by Device, Brazil (R$), 2004-2010 Exhibit 6-10: Nonfusion Market Growth, by Device, Brazil, 2005-2010 Exhibit 6-11: Nonfusion Market, by Device, Brazil, as a % of Total, 2005- 2010 Exhibit 6-12: Nonfusion Market, by Sector, Brazil (US$), 2005 Exhibit 6-13: Nonfusion Market, by Sector, Brazil (R$), 2005