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Cancer Vaccines and Tumor Immunity
John Wiley and Sons Ltd, March 2008, Pages: 334
Cancer vaccine development has changed from a small-scale academic enterprise in to an applied science requiring a large clinical research infrastructure. In this book, a team of expert contributors take a focused look at the hot emerging area of cancer vaccines and tumor immunity. Cancer Vaccines and Tumor Immunity serves a unique role in that it presents as a continuum the basic science discoveries that have moved forward into clinical trials. It is a one-stop, concise reference for all those interested in cancer vaccines, summarizing where we have come from, demonstrating what we are currently doing, and identifying the next major advances.
-Discusses how our new and developing understanding of T-regulatory cells and autoimmunity will impact cancer vaccine design
-Offers a unique look forward into how vaccination in the context of bone marrow transplantation will open new avenues for clinical study
-Offers an exceptional presentation of how modern genomic analysis of normal and tumor tissue will help to identify the next generation of cancer vaccine targets
Author Info:
Rimas J. Orentas, PhD, is Associate Professor in the Department of Pediatrics, Section of Hematology-Oncology, and holds joint appointments in the Departments of Medicine and Microbiology and Molecular Genetics at the Medical College of Wisconsin in Milwaukee, Wisconsin.
JAMES W. HODGE, PhD, is a Senior Scientist in the Laboratory of Tumor Immunology and Biology at the National Cancer Institute in Bethesda, Maryland.
BRYON D. JOHNSON, PhD, is Associate Professor in the Department ofPediatrics, Section of Hematology-Oncology at the Medical College of Wisconsin in Milwaukee, Wisconsin.
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