RNA and DNA Editing: Molecular Mechanisms and Their Integration into Biological Systems - Market Research Reports - Research and Markets

Printer Friendly

Printed from http://www.researchandmarkets.com/reports/591845

RNA and DNA Editing: Molecular Mechanisms and Their Integration into Biological Systems

Description:

Latest discoveries in RNA and DNA editing research, with expert forecasts of the field's future directions

RNA and DNA Editing assembles a team of leading experts who present the latestdiscoveries in the field alongside the latest models and methodology. In addition,the authors set forth the many open questions and suggest routes for further investigation. Overall, the book serves as a practical guide for professionals in the field who need to understand the interrelationship of RNA and DNA editing with other chemical and biological processes.

This book is divided into four sections, providing a clear, contextual map of the field:

Diversification of the Proteome through RNA and DNA Editing discusses the occurrence of editing sites within transcriptomes and their distribution within individual RNAs in order to explore why nucleic acid sequences are edited instead of encoded genomically

Functional Coordination of RNA Editing with Other Cellular Mechanisms brings to the forefront why RNA and DNA editing is essential for cell survival and adaptation

Predictive Studies underscores the power of computational approaches in identifying novel editing sites and predicting the biological consequences of editing at these sites

Structural Approaches presents comparative structural analyses that suggest conserved protein folds and implicate, in some instances, their ancient phylogenic origins as components of editing machinery

This book not only discusses the current state of research in depth, it also gives new contributors an opportunity to express their vision. The perspectives voiced by these authors are provocative and intended to motivate discussion and inspire new experiments. Finally, this book will promote new hypotheses and models that can serve as springboards for the next generation of discoveries in the field.

Contents:

Preface.
Acknowledgements.

Contributors.

Part I: Diversification of the Proteome through RNA and DNA Editing.

Chapter 1. Diversifying Exon Code Through A-To-I RNA Editing.

Chapter 2. Antibody Gene Diversification by Aid-Catalyzed DNA Editing.

Chapter 3. Protein-Protein and RNA-Protein Interactions in U-Insertion/Deletion RNA Editing Complexes.

Chapter 4. Machinery of RNA editing in Plant Organelles.

Part II: Functional Coordination of RNA Editing With Other Cellular Mechanisms.

Chapter 5. Transfer RNA Editing Enzymes: At the Crossroads of Affinity and Specificity.

Chapter 6. A-To-I Editing as a Co-Transcriptional RNA Processing Event.

Chapter 7. Studying and Working with Ribonucleoproteins that Catalyze H/ACA Guided RNA Modification.

Chapter 8. Functional Roles of Spliceosomal SNRNA Modifications in Pre-mRNA Splicing.

Chapter 9. A Role for A-To-I Editing in Gene Silencing.

Chapter 10. biological Implications and Broader-Range Functions For Apobec-1 and Apobec-1 Complementation Factors (ACF)

Chapter 11. Antiviral Function of APOEC3 Cytidine Deaminases.

Part III: Predictive Structures.

Chapter 12. A-To-I Editing of ALU Repeats.

Chapter 13. RNA Editing in Dinoflagellates and Implications for the Evolutionary History of the Editing Machinery.

Part IV: Structural Approaches.

Chapter 14. The Box C/D RNPs: Evolutionarily Ancient Nucleotide Modification Complexes.

Chapter 15. Structural Features of the Adar Family of Enzymes and Their Substrates.

Chapter 16. Chemistry, Phylogeny, and three-Dimensional Structure of the Apobec Protein Family.

Index.

Author

Harold C. Smith, PhD, is Professor in the Department of Biochemistry and Biophysics at the University of Rochester and the founder and Chief Scientific Officer of OyaGen, a biotech company that develops drugs that target editing enzymes. Dr. Smith organized the first Gordon Research Conference on RNA Editing in 1997 and holds four patents.

Ordering:

Order Online - visit http://www.researchandmarkets.com/reports/591845

Order by Fax - using the order form below

Order By Post - print the order form below and send to

Research and Markets,
Guinness Centre,
Taylors Lane,
Dublin 8,
Ireland.

Page 1 of 2
Printed 13/02/2012 12:43:09

Fax Order Form
To place an order via fax simply print this form, fill in the information below and fax the completed form to
646-607-1907 (from USA) or +353 1 6849977 (from Rest of World). If you have any questions please email help@researchandmarkets.net

Order information
Please verify that the product information is correct and select the format you require.


Product Name:
RNA and DNA Editing: Molecular Mechanisms and Their Integration into Biological Systems
Web Address:
http://www.researchandmarkets.com/reports/591845
Office Code:
OC8IHINLSNNSS

Report formats
Please enter the quantity of the report format you require.

	Format	Quantity	Price
	Hard Copy		€136.00 + EUR€ 25.00 Shipping/Handling *

* Shipping/Handling is only charged once per order.

Contact information
Please enter all the information below in BLOCK CAPITALS.


	First Name:	Last Name:
	Email Address:
	Job Title:
	Organisation:
	Address:
	City:
	Postal/Zip Code:
	Country:
	Phone Number:
	Fax Number:

Please fax this form to:
(646) 607-1907 or (646) 964-6609 (from USA)
+353-1-481-1716 or +353-1-653-1571 (from Rest of World)

Page 2 of 2
Printed 13/02/2012 12:43:09

Payment information

Please indicate the payment method you would like to use by selecting the appropriate box.

Pay by Credit Card:

	American Express
	Diners Club
	Master Card
	Visa


Cardholder's Name:

Cardholder's Signature:

Expiry Date:	/

Card Number:

CVV Security Code:

Issue Date:	/ (Diners Club only)

Pay by Check:

Please post the check, accompanied by this form, to:

Research and Markets,
Guinness Centre,
Taylors Lane,
Dublin 8,
Ireland.

Pay by Wire Transfer:

Please transfer funds to:


Account number:	83313083
Sort code:	98-53-30
Swift code:	ULSBIE2D
IBAN number:	IE78ULSB98533083313083
Bank Address:	Ulster Bank, 27-35 Main St, Blackrock, Co. Dublin, Ireland.

If you have a Marketing Code please enter it below:
	Marketing Code:

Please note that by ordering from Research and Markets you are agreeing to our Terms and Conditions at http://www.researchandmarkets.com/info/terms.asp

Please fax this form to:
(646) 607-1907 or (646) 964-6609 (from USA)
+353-1-481-1716 or +353-1-653-1571 (from Rest of World)