Contents:

I. SCOPE AND METHODOLOGY II. REPORT SYNOPSIS 1. Introduction DNA - An Introduction Localization of DNA Composition of DNA Structure of DNA Heredity and DNA Definitions of Important Terms Legend Gene Proteins Translation Circular Proteins Inteins Molecular Chaperones Proteomics DNA Plasmid BAC Vector Insert Shotgun Sequencing Phenotype Genotype History of DNA and Genome Sequencing Discovery of DNA DNA Sequencing Sanger’s Method Maxam and Gilbert Method Pyrosequencing Method Shot Gun Sequencing Method Capillary Array Electrophoresis Technique Genome Sequencing Human Genome Project Sequencing Mitochondrial DNA Historical Perspective (1700-2007) Segmentation of DNA Sequencing Exhibit 1: Segmentation of Global DNA Sequencing Market by Methods (Automated and Non-Automated), Applications (Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics) and Instruments/Software (Instruments and Bio-informatics) 2. Global Market Analysis Exhibit 2: DNA Sequencing (2005-2012) – Global Market Analysis (Current and Future) in US$ Billion (Graphical Representation Included) Analysis by Method Automated Exhibit 3: Automated DNA Sequencing (2005-2012) – Global Market Analysis (Current and Future) by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World in US$ Billion (Graphical Representation Included) Exhibit 4: Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World Non-Automated Exhibit 5: Non-Automated DNA Sequencing (2005-2012) – Global Market Analysis (Current and Future) by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World in US$ Billion (Graphical Representation Included) Exhibit 6: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World Analysis by Application Medical Research Exhibit 7: DNA Sequencing in Medical Research (2005-2012) – Global Market Analysis (Current and Future) by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World in US$ Billion (Graphical Representation Included) Exhibit 8: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World Agriculture & Animal Husbandry Exhibit 9: DNA Sequencing in Agricultural and Animal Husbandry (2005-2012) – Global Market Analysis (Current and Future) by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World in US$ Billion (Graphical Representation Included) Exhibit 10: DNA Sequencing in Agricultural and Animal Husbandry (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World DNA Testing & Forensics Exhibit 11: DNA Sequencing in Testing and Forensics (2005-2012) – Global Market Analysis (Current and Future) by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World in US$ Billion (Graphical Representation Included) Exhibit 12: DNA Sequencing in Testing and Forensics (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World Analysis by Instruments/Software Instruments Exhibit 13: DNA Sequencing Instruments (2005-2012) – Global Market Analysis (Current and Future) by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World US$ Billion (Graphical Representation Included) Exhibit 14: DNA Sequencing Instruments (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World Bio-Informatics Exhibit 15: Bio-Informatics for DNA Sequencing (2005-2012) – Global Market Analysis (Current and Future) by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World in US$ Billion (Graphical Representation Included) Exhibit 16: Bio-Informatics for DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World Exhibit 17: List of Major Global Companies 3. Regional Market Analysis North America Exhibit 18: DNA Sequencing (2005-2012) – North American Market Analysis (Current and Future) in US$ Billion (Graphical Representation Included) Major Companies in North America 454 Life Sciences (USA) Abbott Laboratories (USA) Affymetrix, Inc. (USA) Agencourt Bioscience Corporation (USA) Agilent Technologies, Inc. (USA) Applied Biosystems Group (USA) BD Biosciences (USA) Beckman Coulter, Inc. (USA) BioTrove, Inc. (USA) Cogenics (A Division of Clinical Data) (USA) Commonwealth Biotechnologies, Inc. (USA) Crime Scene Technologies LLC (USA) DNA LandMarks, Inc. (Canada) Epicentre Biotechnologies (USA) Gene Logic, Inc. (USA) Gen-Probe, Inc. (USA) Helicos BioSciences Corporation (USA) Illumina, Inc. (USA) Integrated DNA Technologies, Inc. (USA) Invitrogen, Inc. (USA) Luminex Molecular Diagnostics (Canada) Nimblegen Systems, Inc. (USA) PrimmBiotech, Inc. (USA) Promega Corp. (USA) Sequetech Corp. (USA) Third Wave Technologies, Inc. (USA) Analysis by Method Automated Exhibit 19: Automated DNA Sequencing (2005-2012) –North American Market Analysis (Current and Future) by Geographic Region for the United States and Canada in US$ Billion (Graphical Representation Included) Exhibit 20: Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value by Geographic Region for the United States and Canada (Graphical Representation Included) Non-Automated Exhibit 21: Non-Automated DNA Sequencing (2005-2012) –North American Market Analysis (Current and Future) by Geographic Region for the United States and Canada in US$ Billion (Graphical Representation Included) Exhibit 22: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of the North American Market Value by Geographic Region for the United States and Canada (Graphical Representation Included) Analysis by Application Medical Research Exhibit 23: DNA Sequencing in Medical Research (2005-2012) –North American Market Analysis (Current and Future) by Geographic Region for the United States and Canada in US$ Billion (Graphical Representation Included) Exhibit 24: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value by Geographic Region for the United States and Canada (Graphical Representation Included) Agriculture & Animal Husbandry Exhibit 25: DNA Sequencing in Agriculture & Animal Husbandry (2005-2012) – North American Market Analysis (Current and Future) by Geographic Region for the United States and Canada in US$ Billion (Graphical Representation Included) Exhibit 26: DNA Sequencing Agriculture & Animal Husbandry (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value by Geographic Region for the United States and Canada (Graphical Representation Included) DNA Testing & Forensics Exhibit 27: DNA Sequencing in Testing and Forensics (2005-2012) –North American Market Analysis (Current and Future) by Geographic Region for the United States and Canada in US$ Billion (Graphical Representation Included) Exhibit 28: DNA Sequencing Testing and Forensics (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value by Geographic Region for the United States and Canada (Graphical Representation Included) Analysis by Instruments/Software Instruments Exhibit 29: DNA Sequencing Instruments (2005-2012) –North American Market Analysis (Current and Future) by Geographic Region for the United States and Canada in US$ Billion (Graphical Representation Included) Exhibit 30: DNA Sequencing Instruments (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value by Geographic Region for the United States and Canada (Graphical Representation Included) Bio-Informatics Exhibit 31: DNA Sequencing in Bio-Informatics (2005-2012) –North American Market Analysis (Current and Future) by Geographic Region for the United States and Canada in US$ Billion (Graphical Representation Included) Exhibit 32: DNA Sequencing in Bio-Informatics (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value by Geographic Region for the United States and Canada (Graphical Representation Included) Europe Exhibit 33: DNA Sequencing (2005-2012) – European Market Analysis (Current and Future) in US$ Billion (Graphical Representation Included) Major Companies in Europe Advalytix AG (Germany) bioMérieux SA (France) Biotage AB (Sweden) Cytocell Technologies Ltd. (UK) Dako A/S (Denmark) DNAVision SA (Belgium) Eppendorf AG (Germany) Eurofins Medigenomix GmbH (Germany) Exiqon A/S (Denmark) Febit Biotech GmbH (Germany) Geneart AG (Germany) Kreatech Holding B.V (The Netherlands) Microsynth AG (Switzerland) MilleGen SA (France) MWG Biotech AG (Germany) Qiagen NV (The Netherlands) Tepnel Life Sciences plc (UK) Wellcome Trust Sanger Institute (The) (UK) Analysis by Method Automated DNA Sequencing Exhibit 34: Automated DNA Sequencing (2005-2012) – European Market Analysis (Current and Future) by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included) Exhibit 35: Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe Non-Automated DNA Sequencing Exhibit 36: Non-Automated DNA Sequencing (2005-2012) – European Market Analysis (Current and Future) by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included) Exhibit 37: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe Analysis by Application Medical Research Exhibit 38: DNA Sequencing in Medical Research (2005-2012) – European Market Analysis (Current and Future) by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included) Exhibit 39: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe Agriculture & Animal Husbandry Exhibit 40: DNA Sequencing in Agriculture & Animal Husbandry (2005-2012) – European Market Analysis (Current and Future) by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included) Exhibit 41: DNA Sequencing Agriculture & Animal Husbandry (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe DNA Testing & Forensics Exhibit 42: DNA Sequencing in Testing and Forensics (2005-2012) – European Market Analysis (Current and Future) by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included) Exhibit 43: DNA Sequencing in Testing and Forensics (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe Analysis by Instruments/Software Instruments Exhibit 44: DNA Sequencing Instruments (2005-2012) –European Market Analysis (Current and Future) by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included) Exhibit 45: DNA Sequencing Instruments (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe Bio-Informatics Exhibit 46: DNA Sequencing in Bio-Informatics (2005-2012) –European Market Analysis (Current and Future) by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included) Exhibit 47: DNA Sequencing in Bio-informatics (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Geographic Region for Germany, UK, France, Switzerland and Rest of Europe Asia-Pacific Exhibit 48: DNA Sequencing (2005-2012) – Asia-Pacific Market Analysis (Current and Future) in US$ Billion (Graphical Representation Included) Major Companies in Asia-Pacific AgriGen Biotech Pty Ltd. (Australia) Avestha Gengraine Technologies Pvt. Ltd. (India) BGI Life Tech Co., Ltd. (China) Bioneer, Inc. (South Korea) Genetic Technologies Limited (Australia) GeneWorks Pty. Ltd. (Australia) GVK BIO (India) Ocimum Biosolutions Ltd. (India) Research Biolabs Pte Ltd. (Singapore) Sangon Biological Engineering Technology & Services Co., Ltd. (China) Saturn Biotech Ltd. (Australia) Analysis by Method Automated DNA Sequencing Exhibit 49: Automated DNA Sequencing (2005-2012) –Asia-Pacific Market Analysis (Current and Future) by Geographic Region for Australia, China, India and Rest of Asia-Pacific in US$ Million (Graphical Representation Included) Exhibit 50: Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Geographic Region for Australia, China, India and Rest of Asia-Pacific Non-Automated DNA Sequencing Exhibit 51: Non-Automated DNA Sequencing (2005-2012) –Asia-Pacific Market Analysis (Current and Future) by Geographic Region for Australia, China, India and Rest of Asia-Pacific in US$ Million (Graphical Representation Included) Exhibit 52: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Geographic Region for Australia, China, India and Rest of Asia-Pacific Analysis by Application Medical Research Exhibit 53: DNA Sequencing in Medical Research (2005-2012) – Asia-Pacific Market Analysis (Current and Future) by Geographic Region for Australia, China, India and Rest of Asia-Pacific in US$ Million (Graphical Representation Included) Exhibit 54: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Geographic Region for Australia, China, India and Rest of Asia-Pacific Agriculture & Animal Husbandry Exhibit 55: DNA Sequencing in Agriculture & Animal Husbandry (2005-2012) – Asia-Pacific Market Analysis (Current and Future) by Geographic Region for Australia, China, ndia and Rest of Asia-Pacific in US$ Million (Graphical Representation Included) Exhibit 56: DNA Sequencing Agriculture & Animal Husbandry (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Geographic Region for Australia, China, India and Rest of Asia-Pacific DNA Testing & Forensics Exhibit 57: DNA Sequencing in Testing and Forensics (2005-2012) – Asia-Pacific Market Analysis (Current and Future) by Geographic Region for Australia, China, India and Rest of Asia-Pacific in US$ Million (Graphical Representation Included) Exhibit 58: DNA Sequencing in Testing and Forensics (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Geographic Region for Australia, China, India and Rest of Asia-Pacific Analysis by Instruments/Software Instruments Exhibit 59: DNA Sequencing Instruments (2005-2012) – Asia-Pacific Market Analysis (Current and Future) by Geographic Region for Australia, China, India and Rest of Asia-Pacific in US$ Billion (Graphical Representation Included) Exhibit 60: DNA Sequencing Instruments (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Geographic Region for Australia, China, India and Rest of Asia-Pacific Bio-Informatics Exhibit 61: DNA Sequencing in Bio-Informatics (2005-2012) – Asia-Pacific Market Analysis (Current and Future) by Geographic Region for Australia, China, India and Rest of Asia-Pacific in US$ Million (Graphical Representation Included) Exhibit 62: DNA Sequencing in Bio-Informatics (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Geographic Region for Australia, China, India and Rest of Asia-Pacific Japan Exhibit 63: DNA Sequencing (2005-2012) – Japanese Market Analysis (Current and Future) in US$ Billion (Graphical Representation Included) Major Companies in Japan Hokkaido System Science Co., Ltd. Shimadzu Corporation Rest of World Exhibit 64: DNA Sequencing (2005-2012) – Rest of World Market Analysis (Current and Future) in US$ Billion (Graphical Representation Included) Major companies in Rest of World Hy Laboratories Ltd. (Israel) Inqaba Biotechnical Industries (Pty) Ltd. (South Africa) III. PRODUCT/TECHNOLOGY RESEARCH 1. Introduction Replication of DNA Protein Synthesis and DNA Isolation and Amplification of DNA Gel electrophoresis of DNA Sequencing DNA Polymerase Chain Reaction – Xeroxing DNA The Principle behind PCR The Technique Explained Optimizing the PCR Variations on the Basic PCR Technique Allele-Specific PCR Assembly PCR Asymmetric PCR Colony PCR Helicase-dependent Amplification Hot-start PCR Intersequence Specific (ISSR) PCR Inverse PCR Ligation-Mediated PCR Methylation Specific PCR Multiplex Ligation-dependent Probe Amplification (MLPA) Multiplex-PCR Nested PCR Quantitative PCR RT-PCR TAIL-PCR Touchdown PCR Electrophoretic Techniques Properties and Applications of Supporting Media Paper Electrophoresis Cellulose Acetate Electrophoresis Thin Layer Electrophoresis Gel Electrophoresis Types of Electrophoretic Techniques High Voltage Electrophoresis Continuous Electrophoresis Discontinuous (Disc) Electrophoresis Immunoelectrophoresis Isoelectric Focusing Two-dimensional Gel Electrophoresis Pulsed Field Gel Electrophoresis (PFGE) Isotachphoresis DNA Sequencing Growth Trends – Global Markets Exhibit 65: Global Market for DNA Sequencing: Geographic Regions (Japan, Rest of World, Asia-Pacific, Europe and North America) Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included) DNA Sequencing – Methods and Technologies DNA Sequencing Basics Fragment Sequencing Sequence Assembly Database Processing Genotyping and Linkage Analysis Traditional Methods The Four Best Known DNA Sequencing Techniques Sanger Method and its Most Important Variants (Enzymatic Methods) Sanger DNA Sequencing Simulation Chain-Termination Method Maxam and Gilbert Method Dye-Terminator Sequencing Pyrosequencing Principle of Pyrosequencing Strengths of Pyrosequencing Protocols for DNA Sequencing Bst-catalyzed Radiolabeled DNA Sequencing Radiolabeled Sequencing Gel Preparation, Loading and Electrophoresis Taq-Polymerase Catalyzed Cycle Sequencing Using Fluorescent-Labeled Dye Primers Taq-Polymerase Catalyzed Cycle Sequencing Using Fluorescent-Labeled Dye Terminator Reactions Fluorescent-Labeled Sequencing Gel Preparation, Pre-Electrophoresis, Sample Loading, Electrophoresis, Data Collection, and Analysis on the ABI 373A DNA Sequencer Double-Stranded Sequencing of cDNA Clones Containing Long Poly(A) Tails Using Anchored Poly(Dt) Primers cDNA Sequencing Based on PCR and Random Shotgun Cloning DNA Sequencing- Service Providing Methods Basic DNA Sequencing Standard DNA Sequencing Ready-Run DNA Sequencing Direct PCR DNA Sequencing Special DNA Sequencing Services TA Clone DNA Sequencing Confirmation DNA Sequencing FDA Quality DNA Sequencing Mutation Discovery DNA Sequencing SNP Discovery DNA Sequencing Introduction to Shotgun Sequencing Method Involved in Shotgun Sequencing Working Procedure Importance of Whole Genome Shotgun Sequencing Latest Developments and Sophistications in the Field of Shotgun Sequencing 2. DNA Sequencing Methods Growth Trends - Global DNA Sequencing by Methods Exhibit 66: Global Market for DNA Sequencing: Methods (Automated and Non-Automated) Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included) Automated Growth Trends - Global Market for Automated DNA Sequencing Exhibit 67: Global Market for Automated DNA Sequencing : Geographic Regions (Japan, Rest of World, Asia-Pacific, Europe and North America) Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included) Automated Sequencing Cycle Sequencing Technique Principle of DNA Sequencing Denaturation Annealing Extension Molecule Separation Detection on an Automated Sequencer Asembling the Sequenced Parts of a Gene Automated Sequencer Automated Sequencing with Fluorescent Dyes Need for Automated Sequencing Refinements in Automation Waste Minimization Procedure Advantages Disadvantages Automated Sequencing Gel Automated DNA Sequencing Guidelines Host Strain Recommendations General Information about Templates DNA Isolation Kits GC Rich Templates Non-Automated Growth Trends – Global Market for Non-Automated DNA Sequencing Exhibit 68: Global Market for Non-Automated DNA Sequencing : Geographic Regions (Japan, Rest of World, Asia-Pacific, Europe and North America) Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included) 3. DNA Sequencing Applications Growth Trends – Global Market for DNA Sequencing by Applications Exhibit 69: Global Market for DNA Sequencing: Applications (DNA Testing/ Forensics, Agriculture/Animal Husbandry and Medical Research) Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included) Medical Research Growth Trends – Global Market for DNA Sequencing in Medical Research Exhibit 70: Global Market for DNA Sequencing in Medical Research: Geographic Regions (Japan, Rest of World, Asia-Pacific, Europe and North America) Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included) DNA Sequencing in Medical Research Discovering a Drug Understanding the Mechanism of a Disease What are Genetic Disorders? Identification of Target for Aiming Drug Discovery Role of Functional Genomics in Drug Discovery Target Validation Applications of DNA Sequencing Drug Discovery and Development–The Cost Angle Genotyping and SNPs High-Throughput Genotyping Technology Implications of Drug Discovery and Deveopment Proteomics Pharmacogenomics Benefits of Pharmacogenomics More Powerful Medicines Better, Safer Drugs - The First Time More Accurate Methods of Determining Appropriate Drug Dosages Advanced Screening for Disease Better Vaccines Improvements in the Drug Discovery and Approval Process Decrease in the Overall Cost of Health Care Developments in Pharmacogenomics Pharmacogenomics Holds Tremendous Potential Sequencing the Pieces of Pharmacogenomics and Drug Development Impact of Pharmacogenomics on Clinical Trials More Effective Pharmaceuticals Genetic Testing, Therapy Pharmacogenomics for Today Pharmacogenomics for Lung Cancer Pharmacogenomics – Finding the Competitive Edge for Genetic Variation Field of Molecular Diagnostics Agriculture & Animal Husbandry Growth Trends – Global Market for DNA Sequencing in Agriculture and Animal Husbandry Exhibit 71: Global Market for DNA Sequencing in Agriculture & Animal Husbandry: Geographic Regions (Rest of World, Asia-Pacific, Japan, Europe and North America) Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included) Genomics and Biotechnology in Agricultural Industry DNA Sequencing in Animal Husbandry Introduction Advantages of DNA-based Products DNA Sequencing in Cattle DNA Markers to Improve Milk Production in Cattle DNA Sequencing of Cattle Disease Agents Sequencing of Microbes that Cause Leptospirosis Transgenic Animals Animal Welfare and the Environment The use of Transgenic Animals to Improve Health of Human Beings Domestic Animal Genomics Bovine Genome Sequencing Project Genome Project Promises a Beef Production Revolution The Effect of Genetics and Genomics in Improving Beef Quality Effect of Breeding on Beef Quality Monogenic Inheritance of Beef Quality: The Double Muscling Character Polygenic Inheritance of Beef Quality Trans-Tasman Super Cow Sheep Genomics The Kangaroo Genome Use of Marsupials in Comparative Genomics The Kangaroo Genome Project Poultry Gene Expression Profiling and the Discovery of Functional Genomics of Poultry DNA Sequencing of an Avian Septicemic strain of Eschrichia coli New Developments in Poultry Breeding Sequencing of the Chicken Genome Use of Genetic Information in Breeding Programs Genomics – Poultry Breeding and the Poultry Industry Horse Genome Sequence Equine Herpesvirus-1 Neurological Disease (EHV-1) DNA Sequencing in Pig Uses of a Genome Map Application of DNA Sequencing in the Field of Aquaculture Introduction and Overview Development of Potential Brood Stock and Steps to Improve Application of Transgenic Technology in Aquaculture Development Vital statistics of DNA Sequencing in Intensive Aquaculture Benefits Derived by Using DNA Sequencing in the Field of Mariculture Application of Transgenic Fish to Better Understand the Various Aspects of Environment Commercial Culturing of Transgenic Fish Application of transgenic Fish as Model Animal in environmental Toxicology Deriving Vitamin C from Transgenic Fish Use of Aplysia Sequencing in Various Scientific Fields as Model Organism Culturing of Shrimp Genome Study of Population Genetics of the Cave Shrimp Typhlatya DNA Testing & Forensics Growth Trends – Global Market for DNA Sequencing in Testing and Forensics Exhibit 72: Global Market for DNA Sequencing in Testing and Forensics : Geographic Regions (Japan, Rest of World, Asia-Pacific, Europe and North America) Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included) DNA Sequencing and its Application in Forensics Introduction and Overview Methods Adopted in Forensic Identification DNA Sequencing Considered an Effective Means of Detecting Lineage and Parenthood Application of DNA Technologies in Forensic Investigations Polymerase Chain Reaction Analysis Short Tandem Repeat (STR) Technology Mitochondrial DNA Analysis to Analyze Matrilineal Lineage Y-Chromosome an Important Indicator of Patrilineal Linage DNA Forensics Databases Concerns Pertaining to DNA Data Banking Advantages of DNA Forensics Effectiveness of DNA Fingerprinting Application of DNA Fingerprinting in Human Health Studies Benefits of DNA Fingerprints Statistical Viewpoint of Interpretation of DNA Matching Relevance of Forensic Archaeology in the Study of Forensics DNA Forensics and Crime Relating the Biological Evidence to Solve Criminal Cases Advantages of Maintaining DNA Databases of Arrested Criminals Requirements to Meet the Challenges of Bio-Terrorism Trends Set by Forensic Anthropology in Crime Control Identification and Treatment of Genetically Inherited Disorders Identification of Individuals Function of Microbial Forensics Benefits Attributed to the Use of Microbial Forensics Varied Function of Forensic Entomology Urban Stored Products Forensics Medico Legal Forensics Entomology Characteristics of Forensic Pathology DNA Testing Introduction Strongholds and Constraints of DNA Testing Exquisite Sensitivity Application to any Body Tissue DNA Stability vis-à-vis Proteins DNA Polymorphims Tandemly Repeated DNA Variability in Restriction Sites Techniques for DNA Testing Single Location DNA Fingerprinting Multi-Positional DNA Fingerprinting Applications of DNA Testing 4. DNA Sequencing Instruments/Software Growth Trends – Global Market for DNA Sequencing by Instruments/Software Exhibit 73: Global Market for DNA Sequencing: Instruments/Software (Instruments and Bio-Informatics) Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included) Instruments Growth Trends – Global Market for DNA Sequencing Instruments Exhibit 74: Global Market for DNA Sequencing Instruments : Geographic Regions (Japan, Rest of World, Asia-Pacific, Europe and North America) Ranked by Projected CAGR for 2005 through 2012 (Graphical Representation Included) DNA Sequencer Concept of DNA Microarray Technology Principle and Role in Molecular Diagnostics Relation Between Probes and Array Development Process of Target Labelling in Co-ordination with Detection Systems Prospective Application of DNA Microarray in Veterinary Diagnostics Various Applications of DNA Microarrays Gene Expression Profiling of mRNA Comparative Genomic Hybridization (CGH) SNP Detection Arrays Chromatin Immuno Precipitation (chIP) Studies Types of Microarrays Spotted Microarrays Oligonucleotide Microarrays Genotyping Microarrays Micro Fluidic Devices Reagents Used in the Sequencing of DNA Functions and Uses of DNA Synthesizer Applications Bio-Informatics Growth Trends – Global Market for DNA Sequencing in Bio-Informatics Exhibit 75: Global Market for DNA Sequencing in Bio-Informatics: Geographic Regions (Japan, Asia-Pacific, Rest of World, Europe and North America) Ranked by Projected CAGR for 2005 through 2012 Bio-Informatics Divisions Data Generation Database Organisation Data Examination Data Association Integrated Data Analysis Database Analysis Drug Discovery and Bio-informatics DNA Sequencing - Research and Development DNA Mapping Chromosome Walking DNA Sequencing in Microbiology Introduction Achievements Highly Developed Sequencing Technologies and Their Influence in Microbiology DNA Sequencing in Probiotics Identification of Probiotic Microorganisms in PCR-Based Analysis Sequencing and Sequence Analysis Molecular Based Approaches to Soil Microbiology Deciphering of the Microorganisms Advancements in Molecular Diagnostic Techniques Genetic Amplification Manufacturing of Highly Potent Antibiotics and Vaccinations Possible Developments Genome Sequencing in Microbes Genome shotgun Sequencing of the Sargasso Sea Community Sequencing Program Understanding of Human Biology and Disease Microbial Genome Sequencing Understanding of Microbial Pathogenesis Screening for Virulence Genes Human Genome Project Prokaryotes and Eukaryotes Chromosomes Genome Eukaryotic Genome C-Value Paradox Origin of HGP Genome Sequencing Goals of HGP Outcome of HGP Ethical Issues Functional Genomics History of HGP Mapping the Genome from a Human Perspective Assembly of Human Genome Research Sequence Functional Characteristics DNA Sequencing Sets its Sights on the Future Human Genome Human DNA Sequence Human Genome Sequence Variation IV. MARKET DYNAMICS 1. Market Overview Purpose of DNA Sequencing Global Market Analysis Exhibit 76: DNA Sequencing (2005-2012) – Global Market Analysis (Current and Future) by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World in US$ Billion (Graphical Representation Included) Exhibit 77: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Geographic Region for North America, Europe, Asia-Pacific, Japan and Rest of World (Graphical Representation Included) Global Market Analysis by Segmentation Analysis by Method Exhibit 78: DNA Sequencing (2005-2012) – Global Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Billion (Graphical Representation Included) Exhibit 79: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Method for Automated and Non-Automated (Graphical Representation Included) Non-Automated Methods Exhibit 80: Non-Automated DNA Sequencing (2005-2012) - Global Market Analysis (Current & Future) by Methods for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Billion (Graphical Representation Included) Exhibit 81: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Method for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 82: DNA Sequencing (2005-2012) – Global Market Analysis (Current and Future) by Application for Medical Research, Agriculture / Animal Husbandry and DNA Testing/Forensics in US$ Billion (Graphical Representation Included) Exhibit 83: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Application for Medical Research, Agriculture / Animal Husbandry and DNA Testing / Forensics (Graphical Representation Included) Medical Research Applications Exhibit 84: DNA Sequencing in Medical Research (2005-2012) - Global Market Analysis (Current and Future) by Application for Molecular Diagnostics, Pharmacogenomics and Proteomics in US$ Billion (Graphical Representation Included) Exhibit 85: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Application for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 86: DNA Sequencing (2005-2012) – Global Market Analysis (Current and Future) by Instruments/Software for Instruments and Bioinformatics in US$ Billion (Graphical Representation Included) Exhibit 87: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Global Market Value by Instruments/Software for Instruments and Bioinformatics (Graphical Representation Included) DNA Sequencing Instruments Exhibit 88: DNA Sequencing Instruments (2005-2012) – Global Market Analysis (Current & Future) by DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Billion (Graphical Representation Included) Exhibit 89: DNA Sequencing Instruments (2005, 2009 and 2012) – Percentage Breakdown of Global Instruments Market Value by DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) 2. Major Global Companies in DNA Sequencing Industry 454 Life Sciences (USA) Abbott Laboratories (USA) Advalytix AG (Germany) Affymetrix, Inc. (USA) Agencourt Bioscience Corporation (USA) Agilent Technologies (USA) AgriGen Biotech Pty Ltd. (Australia) Applied Biosystems Group (USA) Avestha Gengraine Technologies Pvt. Ltd. (India) BD Biosciences (USA) Beckman Coulter, Inc. (USA) BGI Life Tech Co., Ltd. (China) bioMérieux SA (France) Bioneer, Inc. (South Korea) Biotage AB (Sweden) BioTrove, Inc. (USA) Cogenics (A Division of Clinical Data) (USA) Commonwealth Biotechnologies, Inc. (USA) Crime Scene Technologies LLC (USA) Cytocell Technologies Ltd. (UK) Dako A/S (Denmark) DNA LandMarks, Inc. (Canada) DNAVision SA (Belgium) Epicentre Biotechnologies (USA) Eppendorf AG (Germany) Eurofins Medigenomix GmbH (Germany) Exiqon A/S (Denmark) Febit Biotech GmbH (Germany) Gene Logic, Inc. (USA) Geneart AG (Germany) Genetic Technologies Limited (Australia) GeneWorks Pty. Ltd. (Australia) Gen-Probe, Inc. (USA) GVK BIO (India) Helicos BioSciences Corporation (USA) Hokkaido System Science Co., Ltd. (Japan) Hy Laboratories Ltd. (Israel) Illumina, Inc. (USA) Integrated DNA Technologies, Inc. (USA) Invitrogen, Inc. (USA) Inqaba Biotechnical Industries (Pty) Ltd. (South Africa) Kreatech Holding B.V (The Netherlands) Luminex Molecular Diagnostics (Canada) Microsynth AG (Switzerland) MilleGen SA (France) MWG Biotech AG (Germany) Nimblegen Systems, Inc. (USA) Ocimum Biosolutions Ltd. (India) PrimmBiotech, Inc. (USA) Promega Corp. (USA) Qiagen NV (The Netherlands) Research Biolabs Pte Ltd. (Singapore) Sangon Biological Engineering Technology & Services Co., Ltd. (China) Saturn Biotech Ltd. (Australia) Sequetech Corp. (USA) Shimadzu Corp. (Japan) Tepnel Life Sciences plc (UK) Third Wave Technologies, Inc. (USA) Wellcome Trust Sanger Institute (The) (UK) 3. Major Activities in DNA Sequencing Industry OncoMethylome Sciences Offers DNA Profiling Services under Collaboration to Abbott Oncology Compounds Affymetrix Signs Agreement to Acquire USB Corporation Agencourt® Genomic Services to use Applied Biosystems’ SOLiD System in New DNA Sequencing Services Febit in association with Prognosys Biosciences Integrates Latest DNA Sequencing and Microarray Technology Agilent Technologies and BioNanomatrix Combine Technologies for Designing a New Genetic Analysis System Applied Biosystems to Co-develop Applications using Olink’s Proximity Ligation Assay (PLA) Technology BioTrove to Supply OpenArray™ Technology to OncoMethylome Sciences Roche Purchases Entire Stake in 454 Life Sciences Cellectis Associates with Bayer CropScience for the Application of Meganuclease Technology in Plants… Cytogenix Join Hands with Eurogentec for the Development of Syndna™ … Syngenta Collaborates with Biotrove for Enhanced Seed Breeding Employing Genomics Technology … BioServe Signs an Agreement with SeraCare to Acquire Genomics… GATC Biotech Develops Novel DNA Sequencing Technique… Agencourt Enters into Alliance with Affymetrix Clinical Services Lab and NuGEN Technologies for Enhancing the Automated Clinical Whole Blood Sample Expression Profiling… Cambridge Antibody Technology Enters into Alliance with Philochem for the Application of DNA-Encoded Libraries… Clinical Data and Epigenetic Join Hands to offer DNA Methylamine Services… UC-Davis School of Medicine Employs Biotrove’s Openarray™ Technology to Discover the Genetic Variation Association with Common Disease in Humans… Genencor Enters into an Agreement with Integrated Genomics to License Ergo System… Cepheid Purchases Stake in Sangtec for Strengthening R&D and Manufacturing Facility Geneservice Purchases DNA Sequencing Facility Located at Biochemistry Department, University of Oxford SanAir Technologies Incorporates DNA Sequencing Technology for the Identification of Dangerous Microbes… Applied Biosystems and Eagle Collaborate to advance the Single Molecule Detection Device MWG Biotech Purchases Eurofins Medigenomix for Rapid DNA Sequencing Service… bioMérieux Inc., Buys Bacterial Barcodes Inc., the Patent Holder of Pioneering Genotyping Technology Bio-Rad Join Hands with Integrated DNA Technologies for Developing RNAi Tool Sets… Cellectis Receives License to Employ Lexicon Genetics' Isogenic DNA Technology Globally…. Applied Biosystems Acquires Agencourt Personal Genomics… Beckman Coulter Acquires In Vitro Diagnostics Product Licenses to Roche’s Portfolio of Real-Time Polymerase Chain Reaction Patents Geneservice Ltd., Receives Credit as one of the Top-Three Dna Sequencing Suppliers to The Medical Research Council… Antibodies By Design Partners with Japan’s Kazusa DNA Research Institute for Developing Antibody Series Reveo in Association with University of Washington Develops Cost-Effective DNA Sequencing Technology… LGC Acquires Berlin Based AGOWA… 4. Major Product Innovations/Launches in DNA Sequencing Industry Sigma-Aldrich Introduces Imprint™ Kit Based on Bisulfite DNA Modification Technology Applied Biosystems Introduces SOLiD™ System, the New Era DNA Sequencing Platform Roche NimbleGen Introduces 4-plex Gene Expression Arrays and Services Spartan Bioscience Unveils The Spartan DX, the High-tech PCR DNA Analyzer Applied Biosystems Unveils Novel Variant Reporter™ Software for Biomedical Researchers Chromatin Attains Novel Patents for Plant Mini-Chromosome Technology ABI Introduces SOLiD Gene Sequencer Agilent Technologies Introduces High-Capacity Enrichment, Intact Protein Chips DNA Sequencing Kit from Baseclear Agilent Technologies Launches 8-Plex High-Density Microarrays Decode Unveils a New DNA-Based Test for Evaluating the Threat Associated with Type 2 Diabetes AGOWA Unveils Advanced DNA Extraction Kits Applied Biosystems Launches PCR Amplification Kit Perfect for Application With Old, Damaged DNA Samples New DNA chip for Ashkenazi Jewish diseases Transgenomic’s novel DNA Mutation Detection Kits for Application in Whole Primer Fluorescent Capillary Electrophoresis Norgen Biotek Releases Kit for Simultaneous Purification of RNA, DNA, and Proteins from Single Sample Abbott Unveils the Novel DNA Tests (CE-Marked) in Europe Gene Codes Introduce Advanced Version of Sequencher Applied Biosystems Launches Novel Methyl Primer Express® Software Nugen Technologies Designs Novel Products for cDNA Studies and mRNA Amplification Celera’s CE Mark a New Real Time PCR HCV Genotyping Test to be marketed in the EU Beckman Coulter Launches Agencourt® FormaPure™ System Now Improved ELISA Assays in just 18 weeks Velocity11 Launches Novel Microplate Sealing Films Vandalia Research Introduces Solution for Custom DNA Amplification based on PCR… Qiagen Unveils Novel Bisulfite Kit for Application in DNA Methylation Analysis… 454 Life Sciences and Roche Diagnostics Launch Advanced Range of Genome Sequencer 20™ System Biotage Introduces Novel Range of Advanced Solutions Incorporating the Pyrosequencing® platforms SoftGenetics Incorporates Novel Feature Mutation Surveyor Software… Solexa Unveils the New Genome Analysis System for DNA Sequencing, Expression Profiling, RNA Analysis 5. Regional Market Analysis A. North America Analysis by Geographic Region Exhibit 90: DNA Sequencing (2005-2012) –North American Market Analysis (Current and Future) by Geographic Region for the United States and Canada in US$ Billion (Graphical Representation Included) Exhibit 91: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value by Geographic Region for the United States and Canada (Graphical Representation Included) Exhibit 92: List of Major Companies in North America Analysis by Method Exhibit 93: DNA Sequencing (2005-2012) –North American Market Analysis (Current and Future) by Method for (Automated and Non-Automated ) in US$ Billion (Graphical Representation Included) Exhibit 94: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 95: Non-Automated DNA Sequencing (2005-2012) –North American Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Billion (Graphical Representation Included) Exhibit 96: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 97: DNA Sequencing (2005-2012) –North American Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Billion (Graphical Representation Included) Exhibit 98: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics Analysis by Medical Research Application Exhibit 99: DNA Sequencing in Medical Research (2005-2012) – North American Market Analysis by Application (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Billion (Graphical Representation Included) Exhibit 100: DNA Sequencing (2006, 2009 and 2012) - Percentage Breakdown of North American Market Value by Application in Medical Research for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 101: DNA Sequencing (2005-2012) –North American Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Billion (Graphical Representation Included) Exhibit 102: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of North American Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 103: DNA Sequencing Instruments (2005-2012) – North American Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Billion (Graphical Representation Included) Exhibit 104: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of North American Market Value Instruments for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) A1. The United States Exhibit 105: DNA Sequencing (2005-2012) –United States Market Analysis (Current and Future) in US$ Billion (Graphical Representation Included) Analysis by Method Exhibit 106: DNA Sequencing (2005-2012) –United States Market Analysis (Current and Future) by Method for (Automated and Non-Automated) in US$ Billion (Graphical Representation Included) Exhibit 107: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of United States Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 108: Non-Auotmated DNA Sequencing (2005-2012) –United States Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Billion (Graphical Representation Included) Exhibit 109: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of United States Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Applications Exhibit 110: DNA Sequencing (2005-2012) –United States Market Analysis (Current and Future) by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics in US$ Billion (Graphical Representation Included) Exhibit 111: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of United States Market Value by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics Analysis by Medical Research Application Exhibit 112: DNA Sequencing in Medical Research (2005-2012) – United States Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Billion (Graphical Representation Included) Exhibit 113: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of United States Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 114: DNA Sequencing (2005-2012) –United States Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Billion (Graphical Representation Included) Exhibit 115: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of United States Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 116: DNA Sequencing Instruments (2005-2012) – United States Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Billion (Graphical Representation Included) Exhibit 117: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of United States Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) A2. Canada Exhibit 118: DNA Sequencing (2005-2012) –Canadian Market Analysis (Current and Future) in US$ Million (Graphical Representation Included) Analysis by Method Exhibit 119: DNA Sequencing (2005-2012) – Canadian Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 120: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Canadian Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated DNA Sequencing Exhibit 121: Non-Automated DNA Sequencing (2005-2012) – Canadian Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 122: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Canadian Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 123: DNA Sequencing (2005-2012) – Canadian Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 124: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Canadian Market Value by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics (Graphical Representation Included) Analysis by Medical Research Exhibit 125: DNA Sequencing in Medical Research (2005-2012) – Canadian Market Analysis by Application (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 126: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Canadian Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 127: DNA Sequencing (2005-2012) – Canadian Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 128: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Canadian Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 129: DNA Sequencing Instruments (2005-2012) – Canadian Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 130: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of Canadian Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) B. EUROPE Analysis by Geographic Region Exhibit 131: DNA Sequencing (2005-2012) –European Market Analysis (Current and Future) by Geographic Region for Germany, United Kingdom, France, Switzerland and Rest of Europe in US$ Billion (Graphical Representation Included) Exhibit 132: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Geographic Region for Germany, United Kingdom, France, Switzerland and Rest of Europe Exhibit 133: List of Major Companies in Europe Analysis by Method Exhibit 134: DNA Sequencing (2005-2012) –European Market Analysis (Current and Future) by Method for (Automated and Non-Automated ) in US$ Billion (Graphical Representation Included) Exhibit 135: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method of DNA Sequencing Exhibit 136: Non-Automated DNA Sequencing (2005-2012) – European Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 137: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of European Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 138: DNA Sequencing (2005-2012) – European Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Billion (Graphical Representation Included) Exhibit 139: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics (Graphical Representation Included) Analysis by Medical Research Exhibit 140: DNA Sequencing in Medical Research (2005-2012) – European Market Analysis by Application (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Billion (Graphical Representation Included) Exhibit 141: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of European Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 142: DNA Sequencing (2005-2012) – European Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Billion (Graphical Representation Included) Exhibit 143: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of European Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 144: DNA Sequencing Instruments (2005-2012) – European Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Billion (Graphical Representation Included) Exhibit 145: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of European Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) B1. Germany German Market Analysis Exhibit 146: DNA Sequencing (2005-2010) –German Market Analysis (Current & Future) in US$ Million (Graphical Representation Included) Analysis by Method Exhibit 147: DNA Sequencing (2005-2012) –German Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 148: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of German Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 149: Non-Automated DNA Sequencing (2005-2012) – German Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 150: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of German Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 151: DNA Sequencing (2005-2012) – German Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 152: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of German Market Value by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics (Graphical Representation Included) Analysis by Medical Research Exhibit 153: DNA Sequencing in Medical Research (2005-2012) – German Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 154: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of German Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 155: DNA Sequencing (2005-2012) – German Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 156: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of German Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 157: DNA Sequencing Instruments (2005-2012) – German Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 158: DNA Sequencing Instruments (2006, 2009 and 2012) – Percentage Breakdown of German Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) B2. The United Kingdom United Kingdom Market Analysis Exhibit 159: DNA Sequencing (2005-2010) –United Kingdom Market Analysis (Current & Future) in US$ Million (Graphical Representation Included) Analysis by Method Exhibit 160: DNA Sequencing (2005-2012) – United Kingdom Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 161: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of United Kingdom Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 162: Non-Automated DNA Sequencing (2005-2012) –United Kingdom Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 163: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of United Kingdom Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 164: DNA Sequencing (2005-2012) –United Kingdom Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 165: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of United Kingdom Market Value by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics (Graphical Representation Included) Analysis by Medical Research Exhibit 166: DNA Sequencing in Medical Research (2005-2012) –United Kingdom Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 167: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of United Kingdom Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 168: DNA Sequencing (2005-2012) –United Kingdom Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 169: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of United Kingdom Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 170: DNA Sequencing Instruments (2005-2012) –United Kingdom Market Analysis (Current and Future) Instruments for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 171: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of United Kingdom Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) B3. France French Market Analysis Exhibit 172: DNA Sequencing (2005-2010) –French Market Analysis (Current & Future) in US$ Million (Graphical Representation Included) Analysis by Method Exhibit 173: DNA Sequencing (2005-2012) – French Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 174: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of French Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 175: Non-Automated DNA Sequencing (2005-2012) – French Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 176: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of French Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 177: DNA Sequencing (2005-2012) – French Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 178: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of French Market Value by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics (Graphical Representation Included) Analysis by Medical Research Exhibit 179: DNA Sequencing in Medical Research (2005-2012) – French Market Analysis by Application (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 180: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of French Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 181: DNA Sequencing (2005-2012) – French Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 182: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of French Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 183: DNA Sequencing Instruments (2005-2012) – French Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 184: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of French Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) B4. Switzerland Swiss Market Analysis Exhibit 185: DNA Sequencing (2005-2010) – Swiss Market Analysis (Current & Future) in US$ Million (Graphical Representation Included) Analysis by Method Exhibit 186: DNA Sequencing (2005-2012) – Swiss Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 187: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Swiss Market Value by Method for Automated and Non-Automated. Analysis by Non-Automated Method Exhibit 188: Non-Automated DNA Sequencing (2005-2012) – Swiss Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 189: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Swiss Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 190: DNA Sequencing (2005-2012) – Swiss Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 191: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Swiss Market Value by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics Analysis by Medical Research Applications Exhibit 192: DNA Sequencing in Medical Research (2005-2012) – Swiss Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 193: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Swiss Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 194: DNA Sequencing (2005-2012) – Swiss Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 195: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Swiss Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 196: DNA Sequencing Instruments (2005-2012) – Swiss Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 197: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of Swiss Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) B5. Rest of Europe Rest of Europe Market Analysis Exhibit 198: DNA Sequencing (2005-2010) – Rest of Europe Market Analysis (Current & Future) in US$ Million (Graphical Representation Included) Analysis by Method Exhibit 199: DNA Sequencing (2005-2012) – Rest of Europe Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 200: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of Europe Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 201: Non-Automated DNA Sequencing (2005-2012) – Rest of Europe Market Analysis (Current and Future) by Method for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 202: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of Europe Market Value by Method for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 203: DNA Sequencing (2005-2012) – Rest of Europe Market Analysis (Current and Future) by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 204: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of Europe Market Value by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics Analysis by Medical Research Application Exhibit 205: DNA Sequencing in Medical Research (2005-2012) – Rest of Europe Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 206: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Rest of Europe Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 207: DNA Sequencing (2005-2012) – Rest of Europe Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 208: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of Europe Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 209: DNA Sequencing Instruments (2005-2012) – Rest of Europe Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 210: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of Rest of Europe Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) C. ASIA-PACIFIC Analysis by Geographic Region Exhibit 211: DNA Sequencing (2005-2012) –Asia-Pacific Market Analysis (Current and Future) by Geographic Region for Australia, China, India and Rest of Asia in US$ Billion (Graphical Representation Included) Exhibit 212: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Geographic Region for Australia, China, India and Rest of Asia (Graphical Representation Included) Exhibit 213: List of Major Companies in Asia-Pacific Analysis by Method Exhibit 214: DNA Sequencing (2005-2012) – Asia-Pacific Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Billion (Graphical Representation Included) Exhibit 215: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 216: Non-Automated DNA Sequencing (2005-2012) – Asia-Pacific Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 217: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 218: DNA Sequencing (2005-2012) – Asia-Pacific Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Billion (Graphical Representation Included) Exhibit 219: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics (Graphical Representation Included) Analysis by Medical Research Exhibit 220: DNA Sequencing in Medical Research (2005-2012) – Asia-Pacific Market Analysis by Application (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 221: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 222: DNA Sequencing (2005-2012) – Asia-Pacific Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Billion (Graphical Representation Included) Exhibit 223: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Asia-Pacific Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 224: DNA Sequencing Instruments (2005-2012) – Asia-Pacific Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Billion (Graphical Representation Included) Exhibit 225: DNA Sequencing (2006, 2009 and 2012) - Percentage Breakdown of Asia-Pacific Market Value by Instruments for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) C1. Australia Australian Market Analysis Exhibit 226: DNA Sequencing (2005-2010) –Australian Market Analysis (Current & Future) in US$ Million (Graphical Representation Included) Analysis by Method Exhibit 227: DNA Sequencing (2005-2012) – Australian Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 228: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Australian Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 229: Non-Automated DNA Sequencing (2005-2012) – Australian Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 230: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Australian Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 231: DNA Sequencing (2005-2012) – Australian Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 232: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Australian Market Value by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics Analysis by Medical Research Exhibit 233: DNA Sequencing in Medical Research (2005-2012) – Australian Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 234: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Australian Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 235: DNA Sequencing (2005-2012) – Australian Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 236: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Australian Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 237: DNA Sequencing Instruments (2005-2012) – Australian Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 238: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of Australian Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) C2. China Chinese Market Analysis Exhibit 239: DNA Sequencing (2005-2010) – Chinese Market Analysis (Current & Future) in US$ Million (Graphical Representation Included) Analysis by Method Exhibit 240: DNA Sequencing (2005-2012) – Chinese Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 241: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Chinese Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 242: Non-Automated DNA Sequencing (2005-2012) – Chinese Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million Exhibit 243: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Chinese Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other Analysis by Application Exhibit 244: DNA Sequencing (2005-2012) – Chinese Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 245: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Chinese Market Value by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics Analysis by Medical Research Exhibit 246: DNA Sequencing in Medical Research (2005-2012) – Chinese Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 247: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Chinese Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 248: DNA Sequencing (2005-2012) – Chinese Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 249: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Chinese Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 250: DNA Sequencing Instruments (2005-2012) – Chinese Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 251: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of Chinese Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) C3. India Indian Market Analysis Exhibit 252: DNA Sequencing (2005-2010) – Indian Market Analysis (Current & Future) in US$ Million (Graphical Representation Included) Analysis by Method Exhibit 253: DNA Sequencing (2005-2012) – Indian Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 254: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Indian Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 255: Non-Automated DNA Sequencing (2005-2012) – Indian Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 256: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Indian Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 257: DNA Sequencing (2005-2012) – Indian Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 258: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Indian Market Value by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics Analysis by Medical Research Exhibit 259: DNA Sequencing in Medical Research (2005-2012) – Indian Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 260: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Indian Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 261: DNA Sequencing (2005-2012) – Indian Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 262: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Indian Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 263: DNA Sequencing Instruments (2005-2012) – Indian Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 264: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of Indian Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) C4. Rest of Asia-Pacific Rest of Asia-Pacific Market Analysis Exhibit 265: DNA Sequencing (2005-2010) – Rest of Asia-Pacific Market Analysis (Current & Future) in US$ Million (Graphical Representation Included) Analysis by Method Exhibit 266: DNA Sequencing (2005-2012) – Rest of Asia-Pacific Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 267: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of Asia-Pacific Market Value by Method for Automated and Non-Automated (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 268: Non-Automated DNA Sequencing (2005-2012) – Rest of Asia-Pacific Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 269: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of Asia-Pacific Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 270: DNA Sequencing (2005-2012) – Rest of Asia-Pacific Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 271: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of Asia-Pacific Market Value by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics Analysis by Medical Research Exhibit 272: DNA Sequencing in Medical Research (2005-2012) – Rest of Asia-Pacific Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 273: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Rest of Asia-Pacific Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 274: DNA Sequencing (2005-2012) – Rest of Asia-Pacific Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 275: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of Asia-Pacific Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 276: DNA Sequencing Instruments (2005-2012) – Rest of Asia-Pacific Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 277: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of Rest of Asia-Pacific Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) D. Japan Japanese Market Analysis Exhibit 278: DNA Sequencing (2005-2012) – Japanese Market Analysis (Current and Future) in US$ Million (Graphical Representation Included) Exhibit 279: List of Major Companies in Japan Analysis by Method Exhibit 280: DNA Sequencing (2005-2012) – Japanese Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Million (Graphical Representation Included) Exhibit 281: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Japanese Market Value by Method for Automated and Non-Automated (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 282: Non-Automated DNA Sequencing (2005-2012) – Japanese Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 283: Non-Autoamted DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Japanese Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 284: DNA Sequencing (2005-2012) – Japanese Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Million (Graphical Representation Included) Exhibit 285: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Japanese Market Value by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics (Graphical Representation Included) Analysis by Medical Research Exhibit 286: DNA Sequencing in Medical Research (2005-2012) – Japanese Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 287: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Japanese Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 288: DNA Sequencing (2005-2012) – Japanese Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio-Informatics in US$ Million (Graphical Representation Included) Exhibit 289: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Japanese Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 290: DNA Sequencing Instruments (2005-2012) – Japanese Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 291: DNA Sequencing Instruments (2006, 2009 and 2012) – Percentage Breakdown of Japanese Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) E. REST OF WORLD Rest of World Market Analysis Exhibit 292: DNA Sequencing (2005-2012) – Rest of World Market Analysis (Current and Future) in US$ Billion (Graphical Representation Included) Exhibit 293: List of Companies in Rest of World Analysis by Method Exhibit 294: DNA Sequencing (2005-2012) – Rest of World Market Analysis (Current and Future) by Method for Automated and Non-Automated in US$ Billion (Graphical Representation Included) Exhibit 295: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of World Market Value by Method for Automated and Non-Automated. (Graphical Representation Included) Analysis by Non-Automated Method Exhibit 296: Non-Automated DNA Sequencing (2005-2012) – Rest of World Market Analysis (Current and Future) for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other in US$ Million (Graphical Representation Included) Exhibit 297: Non-Automated DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of World Market Value for Sanger’s, Maxam-Gilbert, Pyrosequencing and Other (Graphical Representation Included) Analysis by Application Exhibit 298: DNA Sequencing (2005-2012) – Rest of World Market Analysis (Current and Future) by Application for Medical Research, Agriculture & Animal Husbandry and DNA Testing & Forensics in US$ Billion (Graphical Representation Included) Exhibit 299: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of World Market Value by Application for Medical Research, Agriculture and Animal Husbandry and DNA Testing & Forensics (Graphical Representation Included) Analysis by Medical Research Exhibit 300: DNA Sequencing in Medical Research (2005-2012) – Rest of World Market Analysis (Current and Future) for Proteomics, Pharmacogenomics and Molecular Diagnostics in US$ Million (Graphical Representation Included) Exhibit 301: DNA Sequencing in Medical Research (2006, 2009 and 2012) – Percentage Breakdown of Rest of World Market Value for Proteomics, Pharmacogenomics and Molecular Diagnostics (Graphical Representation Included) Analysis by Instruments/Software Exhibit 302: DNA Sequencing (2005-2012) – Rest of World Market Analysis (Current and Future) by Instruments/Software for Instruments and Bio Informatics in US$ Billion (Graphical Representation Included) Exhibit 303: DNA Sequencing (2006, 2009 and 2012) – Percentage Breakdown of Rest of World Market Value by Instruments/Software for Instruments and Bio-Informatics (Graphical Representation Included) Analysis by Instruments Exhibit 304: DNA Sequencing Instruments (2005-2012) – Rest of World Market Analysis (Current and Future) for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology in US$ Million (Graphical Representation Included) Exhibit 305: DNA Sequencing Instruments (2006, 2009 and 2012) - Percentage Breakdown of Rest of World Market Value for DNA Sequencers, DNA Sequencing Kits, DNA Synthesizers and Microarray Technology (Graphical Representation Included) 6. DNA Sequencing - The Industry Outlook V. CORPORATE DIRECTORY

Companies Mentioned

454 Life Sciences (USA) Abbott Laboratories (USA) Advalytix AG (Germany) Affymetrix, Inc. (USA) Agencourt Bioscience Corporation (USA) Agilent Technologies (USA) AgriGen Biotech Pty Ltd. (Australia) Applied Biosystems Group (USA) Avestha Gengraine Technologies Pvt. Ltd. (India) BD Biosciences (USA) Beckman Coulter, Inc. (USA) BGI Life Tech Co., Ltd. (China) bioMérieux SA (France) Bioneer, Inc. (South Korea) Biotage AB (Sweden) BioTrove, Inc. (USA) Cogenics (A Division of Clinical Data) (USA) Commonwealth Biotechnologies, Inc. (USA) Crime Scene Technologies LLC (USA) Cytocell Technologies Ltd. (UK) Dako A/S (Denmark) DNA LandMarks, Inc. (Canada) DNAVision SA (Belgium) Epicentre Biotechnologies (USA) Eppendorf AG (Germany) Eurofins Medigenomix GmbH (Germany) Exiqon A/S (Denmark) Febit Biotech GmbH (Germany) Gene Logic, Inc. (USA) Geneart AG (Germany) Genetic Technologies Limited (Australia) GeneWorks Pty. Ltd. (Australia) Gen-Probe, Inc. (USA) GVK BIO (India) Helicos BioSciences Corporation (USA) Hokkaido System Science Co., Ltd. (Japan) Hy Laboratories Ltd. (Israel) Illumina, Inc. (USA) Integrated DNA Technologies, Inc. (USA) Invitrogen, Inc. (USA) Inqaba Biotechnical Industries (Pty) Ltd. (South Africa) Kreatech Holding B.V (The Netherlands) Luminex Molecular Diagnostics (Canada) Microsynth AG (Switzerland) MilleGen SA (France) MWG Biotech AG (Germany) Nimblegen Systems, Inc. (USA) Ocimum Biosolutions Ltd. (India) PrimmBiotech, Inc. (USA) Promega Corp. (USA) Qiagen NV (The Netherlands) Research Biolabs Pte Ltd. (Singapore) Sangon Biological Engineering Technology & Services Co., Ltd. (China) Saturn Biotech Ltd. (Australia) Sequetech Corp. (USA) Shimadzu Corp. (Japan) Tepnel Life Sciences plc (UK) Third Wave Technologies, Inc. (USA) Wellcome Trust Sanger Institute (The) (UK)