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Primary Myelofibrosis Market Report and Forecast 2024-2032

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    Report

  • 180 Pages
  • February 2024
  • Region: Global
  • Expert Market Research
  • ID: 5941121

Primary Myelofibrosis Market Outlook

The Primary Myelofibrosis market size was valued at USD 877.43 million in 2023, driven by increasing development of novel therapies. The market size is anticipated to grow at a CAGR of 5.7 % during the forecast period of 2024-2032 to achieve a value of USD 1438.9 million by 2032.

Primary Myelofibrosis: Introduction

Primary Myelofibrosis (PMF) is a rare bone marrow disorder characterized by the excessive production of fibrous scar tissue, which impedes the bone marrow's ability to produce normal blood cells. It leads to severe anemia, weakness, and an enlarged spleen. PMF is part of a group of diseases known as myeloproliferative disorders and can occur on its own or evolve from other related conditions. Symptoms often include fatigue, weight loss, and bone pain.

Key Trends in the Primary Myelofibrosis Market

There's a growing focus on the development of novel therapies, including targeted treatments and JAK inhibitors, which have shown promise in managing symptoms and improving the quality of life for patients with PMF. The FDA's approval of drugs like ruxolitinib has set a precedent for the development of more such targeted therapies.

The market is witnessing an increase in research activities and clinical trials aimed at understanding the pathophysiology of PMF better and developing new treatment modalities. Pharmaceutical companies and research institutions are investing in the discovery of biomarkers and novel drug candidates.

There's a growing emphasis on the early diagnosis of PMF, which is crucial for effective management of the disease. Healthcare professionals are increasingly adopting comprehensive diagnostic approaches, including advanced genetic testing, which helps in the precise classification of myeloproliferative disorders and tailoring of treatment strategies.

The availability and accessibility of advanced treatments for PMF vary significantly across different regions. High-income countries are more likely to have access to the latest therapies and clinical trials, while patients in low and middle-income countries face challenges related to the availability and affordability of treatment.

Patient advocacy groups are becoming more prominent, providing essential support and resources for individuals with PMF. These organizations also play a crucial role in raising awareness, promoting research, and influencing healthcare policies related to PMF.

There's a trend towards personalized or precision medicine in treating PMF, where treatment is tailored based on the individual patient's genetic makeup, disease characteristics, and other personal factors. This approach aims to improve treatment outcomes and reduce side effects.

Primary Myelofibrosis Market Segmentation

Market Breakup by Type

  • Spinocerebellar Primary Myelofibrosiss
  • Primary Myelofibrosis-Telangiectasia
  • Episodic Primary Myelofibrosis
  • Others

Market Breakup by Services

  • Treatment
  • Diagnosis

Market Breakup by Dosage Forms

  • Solid
  • Liquids
  • Others

Market Breakup by Age

  • Adult
  • Child
  • Geriatric

Market Breakup by End User

  • Hospitals
  • Clinics
  • Others

Market Breakup by Region

  • United States
  • EU-4 and the United Kingdom
  • Germany
  • France
  • Italy
  • Spain
  • United Kingdom
  • Japan

Primary Myelofibrosis Market Overview

North America, particularly the United States, leads in research and treatment options for PMF. The region benefits from advanced healthcare infrastructure, a strong focus on innovative drug development, and active patient advocacy groups. There's also a high awareness of PMF and its treatment options, supported by robust healthcare policies and investment in healthcare.

Europe demonstrates a strong commitment to healthcare and research, with numerous centers specializing in the treatment of myeloproliferative disorders like PMF. The region benefits from well-established healthcare systems and substantial government and private investment in medical research. European countries also adhere to stringent regulations ensuring the safety and efficacy of PMF treatments.

Japan is experiencing growth in the PMF market, driven by improving healthcare systems, rising healthcare expenditure, and an increasing awareness of the disorder. Country is investing in healthcare infrastructure and showing interest in advanced treatments. However, access to specialized care and novel treatments may vary significantly within the region.

Primary Myelofibrosis Market: Competitor Landscape

The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players.
  • Bristol-Myers Squibb Company
  • Amneal Pharmaceuticals, Inc.
  • CTI BioPharma Corp
  • Actuate Therapeutics Inc.
  • Pfizer Inc.
  • Galecto
  • Incyte Corporation
  • AbbVie Inc.
  • GlaxoSmithKline plc
  • Imago BioSciences
  • Sanofi
  • F. Hoffmann-La Roche Ltd
  • Mylan NV
  • Hikma Pharmaceuticals PLC
  • Bayer AG


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Table of Contents

1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage - Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Primary Myelofibrosis Overview
3.1 Guidelines and Stages
3.2 Pathophysiology
3.3 Screening and Diagnosis
3.4 Treatment Pathway
4 Patient Profile
4.1 Patient Profile Overview
4.2 Patient Psychology and Emotional Impact Factors
4.3 Risk Assessment and Treatment Success Rate
5 Primary Myelofibrosis Epidemiology Analysis - 7MM
5.1 7MM Epidemiology Scenario Overview (2017-2032)
5.2 United States Primary Myelofibrosis Epidemiology Forecast (2017-2032)
5.3 EU-4 and United Kingdom Primary Myelofibrosis Epidemiology Forecast (2017-2032)
5.3.1 Germany Primary Myelofibrosis Epidemiology Forecast (2017-2032)
5.3.2 France Primary Myelofibrosis Epidemiology Forecast (2017-2032)
5.3.3 Italy Primary Myelofibrosis Epidemiology Forecast (2017-2032)
5.3.4 Spain Primary Myelofibrosis Epidemiology Forecast (2017-2032)
5.3.5 United Kingdom Primary Myelofibrosis Epidemiology Forecast (2017-2032)
5.4 Japan Primary Myelofibrosis Epidemiology Forecast (2017-2032)
6 Primary Myelofibrosis Market Overview - 7MM
6.1 Primary Myelofibrosis Market Historical Value (2017-2023)
6.2 Primary Myelofibrosis Market Forecast Value (2024-2032)
7 Primary Myelofibrosis Market Landscape - 7MM
7.1 Primary Myelofibrosis Developers Landscape
7.1.1 Analysis by Year of Establishment
7.1.2 Analysis by Company Size
7.1.3 Analysis by Region
7.2 Primary Myelofibrosis Product Landscape
7.2.1 Analysis by Products
7.2.2 Analysis by Indications
7.2.3 Analysis by Route of Administration
8 Primary Myelofibrosis Challenges and Unmet Needs
8.1 Treatment Pathway Challenges
8.2 Compliance and Drop-Out Analysis
8.3 Awareness and Prevention Gaps
9 Cost of Treatment
10 Primary Myelofibrosis Market Dynamics
10.1 Market Drivers and Constraints
10.2 SWOT Analysis
10.3 Porter’s Five Forces Model
10.4 Key Demand Indicators
10.5 Key Price Indicators
10.6 Industry Events, Initiatives, and Trends
10.7 Value Chain Analysis
11 Primary Myelofibrosis Market Segmentation - 7MM
11.1 Primary Myelofibrosis Market by Type
11.1.1 Market Overview
11.1.2 Spinocerebellar Primary Myelofibrosis
11.1.3 Primary Myelofibrosis-Telangiectasia
11.1.4 Episodic Primary Myelofibrosis
11.1.5 Others
11.2 Primary Myelofibrosis Market by Services
11.2.1 Market Overview
11.2.2 Treatment
11.2.3 Diagnosis
11.3 Primary Myelofibrosis Market by Dosage Forms
11.3.1 Market Overview
11.3.2 Solid
11.3.3 Liquid
11.3.4 Others
11.4 Primary Myelofibrosis Market by Age
11.4.1 Market Overview
11.4.2 Children
11.4.3 Adult
11.4.4 Geriatric
11.5 Primary Myelofibrosis Market by End User
11.5.1 Market Overview
11.5.2 Hospitals
11.5.3 Clinics
11.5.4 Others
11.6 Primary Myelofibrosis Market by Region
11.6.1 Market Overview
11.6.2 United States
11.6.3 EU-4 and the United Kingdom
11.6.3.1 Germany
11.6.3.2 France
11.6.3.3 Italy
11.6.3.4 Spain
11.6.3.5 United Kingdom
11.6.4 Japan
12 United States Primary Myelofibrosis Market
12.1 Primary Myelofibrosis Market Historical Value (2017-2023)
12.2 Primary Myelofibrosis Market Forecast Value (2024-2032)
12.3 Primary Myelofibrosis Market by Disease Type
12.4 Primary Myelofibrosis Market by Treatment Type
13 EU-4 and United Kingdom Primary Myelofibrosis Market
13.1 Primary Myelofibrosis Market Historical Value (2017-2023)
13.2 Primary Myelofibrosis Market Forecast Value (2024-2032)
13.3 Germany Primary Myelofibrosis Market Overview
13.3.1 Primary Myelofibrosis Market by Disease Type
13.3.2 Primary Myelofibrosis Market by Treatment Type
13.4 France Primary Myelofibrosis Market Overview
13.4.1 Primary Myelofibrosis Market by Disease Type
13.4.2 Primary Myelofibrosis Market by Treatment Type
13.5 Italy Primary Myelofibrosis Market Overview
13.5.1 Primary Myelofibrosis Market by Disease Type
13.5.2 Primary Myelofibrosis Market by Treatment Type
13.6 Spain Primary Myelofibrosis Market Overview
13.6.1 Primary Myelofibrosis Market by Disease Type
13.6.2 Primary Myelofibrosis Market by Treatment Type
13.7 United Kingdom Primary Myelofibrosis Market Overview
13.7.1 Primary Myelofibrosis Market by Disease Type
13.7.2 Primary Myelofibrosis Market by Treatment Type
14 Japan Primary Myelofibrosis Market
14.1 Primary Myelofibrosis Market Historical Value (2017-2023)
14.2 Primary Myelofibrosis Market Forecast Value (2024-2032)
14.2.1 Primary Myelofibrosis Market by Disease Type
14.2.2 Primary Myelofibrosis Market by Treatment Type
15 Patent Analysis
15.1 Analysis by Type of Patent
15.2 Analysis by Publication year
15.3 Analysis by Issuing Authority
15.4 Analysis by Patent Age
15.5 Analysis by CPC Analysis
15.6 Analysis by Patent Valuation
15.7 Analysis by Key Players
16 Grants Analysis
16.1 Analysis by year
16.2 Analysis by Amount Awarded
16.3 Analysis by Issuing Authority
16.4 Analysis by Grant Application
16.5 Analysis by Funding Institute
16.6 Analysis by NIH Departments
16.7 Analysis by Recipient Organization
17 Clinical Trials Analysis
17.1 Analysis by Trial Registration Year
17.2 Analysis by Trial Status
17.3 Analysis by Trial Phase
17.4 Analysis by Therapeutic Area
17.5 Analysis by Geography
18 Funding Analysis
18.1 Analysis by Funding Instances
18.2 Analysis by Type of Funding
18.3 Analysis by Funding Amount
18.4 Analysis by Leading Players
18.5 Analysis by Leading Investors
18.6 Analysis by Geography
19 Partnership and Collaborations Analysis
19.1 Analysis by Partnership Instances
19.2 Analysis by Type of Partnership
19.3 Analysis by Leading Players
19.4 Analysis by Geography
20 Supplier Landscape
20.1 Bristol-Myers Squibb Company
20.1.1 Financial Analysis
20.1.2 Product Portfolio
20.1.3 Demographic Reach and Achievements
20.1.4 Mergers and Acquisition
20.1.5 Certifications
20.2 Amneal Pharmaceuticals, Inc.
20.2.1 Financial Analysis
20.2.2 Product Portfolio
20.2.3 Demographic Reach and Achievements
20.2.4 Mergers and Acquisition
20.2.5 Certifications
20.3 CTI BioPharma Corp
20.3.1 Financial Analysis
20.3.2 Product Portfolio
20.3.3 Demographic Reach and Achievements
20.3.4 Mergers and Acquisition
20.3.5 Certifications
20.4 Actuate Inc.
20.4.1 Financial Analysis
20.4.2 Product Portfolio
20.4.3 Demographic Reach and Achievements
20.4.4 Mergers and Acquisition
20.4.5 Certifications
20.5 Pfizer Inc.
20.5.1 Financial Analysis
20.5.2 Product Portfolio
20.5.3 Demographic Reach and Achievements
20.5.4 Mergers and Acquisition
20.5.5 Certifications
20.6 Galecto
20.6.1 Financial Analysis
20.6.2 Product Portfolio
20.6.3 Demographic Reach and Achievements
20.6.4 Mergers and Acquisition
20.6.5 Certifications
20.7 Incyte Corporation
20.7.1 Financial Analysis
20.7.2 Product Portfolio
20.7.3 Demographic Reach and Achievements
20.7.4 Mergers and Acquisition
20.7.5 Certifications
20.8 AbbVie Inc.
20.8.1 Financial Analysis
20.8.2 Product Portfolio
20.8.3 Demographic Reach and Achievements
20.8.4 Mergers and Acquisition
20.8.5 Certifications
20.9 GlaxoSmithKline plc
20.9.1 Financial Analysis
20.9.2 Product Portfolio
20.9.3 Demographic Reach and Achievements
20.9.4 Mergers and Acquisition
20.9.5 Certifications
20.10 Imago BioSciences
20.10.1 Financial Analysis
20.10.2 Product Portfolio
20.10.3 Demographic Reach and Achievements
20.10.4 Mergers and Acquisition
20.10.5 Certifications
20.11 Sanofi
20.11.1 Financial Analysis
20.11.2 Product Portfolio
20.11.3 Demographic Reach and Achievements
20.11.4 Mergers and Acquisition
20.11.5 Certifications
20.12 F. Hoffmann-La Roche Ltd
20.12.1 Financial Analysis
20.12.2 Product Portfolio
20.12.3 Demographic Reach and Achievements
20.12.4 Mergers and Acquisition
20.12.5 Certifications
20.13 Mylan NV
20.13.1 Financial Analysis
20.13.2 Product Portfolio
20.13.3 Demographic Reach and Achievements
20.13.4 Mergers and Acquisition
20.13.5 Certifications
20.14 Hikma Pharmaceuticals PLC
20.14.1 Financial Analysis
20.14.2 Product Portfolio
20.14.3 Demographic Reach and Achievements
20.14.4 Mergers and Acquisition
20.14.5 Certifications
20.15 Bayer AG
20.15.1 Financial Analysis
20.15.2 Product Portfolio
20.15.3 Demographic Reach and Achievements
20.15.4 Mergers and Acquisition
20.15.5 Certifications
21 Primary Myelofibrosis Market - Distribution Model (Additional Insight)
21.1 Overview
21.2 Potential Distributors
21.3 Key Parameters for Distribution Partner Assessment
22 Key Opinion Leaders (KOL) Insights (Additional Insight)
23 Company Competitiveness Analysis (Additional Insight)
23.1 Very Small Companies
23.2 Small Companies
23.3 Mid-Sized Companies
23.4 Large Companies
23.5 Very Large Companies
24 Payment Methods (Additional Insight)
24.1 Government Funded
24.2 Private Insurance
24.3 Out-of-Pocket
*Additional insights provided are customisable as per client requirements.

Companies Mentioned

  • Bristol-Myers Squibb Company
  • Amneal Pharmaceuticals Inc.
  • CTI BioPharma Corp
  • Actuate Inc.
  • Pfizer Inc.
  • Galecto Incyte Corporation
  • AbbVie Inc.
  • GlaxoSmithKline plc
  • Imago BioSciences
  • Sanofi
  • F. Hoffmann-La Roche Ltd
  • Mylan NV
  • Hikma Pharmaceuticals PLC
  • Bayer AG

Methodology

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Table Information