+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)

Morphea and Related Disorders

  • Book

  • March 2024
  • Bentham Science Publishers Ltd
  • ID: 5960302
Morphea and Related Disorders is a comprehensive reference on morphea. The book covers the subject in 20 chapters. The book starts with a detailed introduction and history of the morphea and its various classifications systems. Next, the book progresses into epidemiology, predisposing factors and pathogenic mechanisms, followed by histopathology for morphea diagnosis and a detailed review of clinical presentations.

Subsequent chapters cover associated diseases and extracutaneous manifestations, medical investigations, treatment guidelines and special topics (Idiopathic atrophoderma of Pasini and Pierini, Linear atrophoderma of Moulin, Parry-Romberg syndrome, Lichen sclerosus, pediatric morphea and eosinophilic fasciitis).

Key Features

The most detailed reference book on morphea
Easy and simple language for readers
Chapter synopsis at the beginning of each chapter
Learning points at the end of the chapter
More than 100 high resolution colored photographs
Information boxes and tables to enhance readability.
Covers basic knowledge on morphea, including pathogenesis, clinical presentations, and classification
Includes guidelines for professionals
Includes chapters on special topics for advanced readers

Morphea and Related Disorders is the definitive reference book for medical students, residents, instructors, and physicians.

Readership

Medical students, instructors, and physicians (dermatologists, rheumatologists, and general physicians)

Table of Contents

CHAPTER 1 INTRODUCTION AND HISTORY
  • Tasleem Arif
  • INTRODUCTION
  • HISTORY
  • REFERENCES
CHAPTER 2 CLASSIFICATION
  • Tasleem Arif and Marwa Sami
  • INTRODUCTION
  • CLASSIFICATION BY O’ LEARY ET AL.
  • Morphea
  • Localized
  • Other Types
  • Linear
  • Localized Forms Associated with Hemiatrophy
  • CLASSIFICATION OF LOCALIZED SCLERODERMA BY RODNAN ET AL (1979)
  • Morphea
  • Linear Scleroderma
  • MODIFIED AMERICAN RHEUMATISM ASSOCIATION (ARA) CLASSIFICATION
  • FOR LOCALIZED SCLERODERMA
  • CLASSIFICATION OF MORPHEA BY PETERSON ET AL.
  • Plaque Morphea
  • Morphea en Plaque
  • Guttate Morphea
  • Atrophoderma of Pasini and Pierini
  • Keloid Morphea
  • Lichen Sclerosus (LS)
  • Generalized Morphea
  • Bullous Morphea
  • Linear Morphea
  • Linear Morphea (Linear Scleroderma)
  • En Coup de Sabre
  • Progressive Hemifacial Atrophy
  • Deep Morphea
  • Subcutaneous Morphea
  • Eosinophilic Fasciitis
  • Morphea Profunda
  • Disabling Pansclerotic Morphea of Children
  • CLASSIFICATION OF MORPHEA BY EUROPEAN PEDIATRIC RHEUMATOLOGY
  • SOCIETY
  • Circumscribed Morphea
  • Generalized Morphea
  • Linear Morphea
  • Pansclerotic Morphea
  • Mixed Morphea
  • CLASSIFICATION OF MORPHEA BY GERMAN DERMATOLOGICAL SOCIETY
  • Limited Type of Localized Scleroderma
  • Generalized Type of Localized Scleroderma
  • Linear Type of Localized Scleroderma
  • Deep Type of Localized Scleroderma
  • UPDATED CLASSIFICATION OF MORPHEA BY GERMAN DERMATOLOGICAL
  • SOCIETY
  • HOLISTIC CLASSIFICATION OF MORPHEA AND RELATED DISORDERS
  • REFERENCES
CHAPTER 3 EPIDEMIOLOGY
  • Parvaiz Anwar and Tasleem Arif
  • INTRODUCTION
  • MAGNITUDE OF MORPHEA AS PUBLIC HEALTH PROBLEM
  • AGE OF INVOLVEMENT
  • CLINICAL ASPECTS OF MORPHEA VERSUS AGE GROUP
  • GENDER CONSIDERATIONS OF MORPHEA
  • RACIAL PREDISPOSITION
  • MORBIDITY
  • REFERENCES
CHAPTER 4 PREDISPOSING FACTORS
  • Sabha Mushtaq and Tasleem Arif
  • INTRODUCTION
  • GENETIC FACTORS
  • EXTERNAL FACTORS
  • Trauma
  • Infection
  • Vaccination
  • Drugs & Chemicals
  • Radiation
  • Malignancy
  • Thyroid Dysfunction
  • Pregnancy
  • Autoimmunity
  • REFERENCES
CHAPTER 5 PATHOGENESIS
  • Mohammad Adil and Tasleem Arif
  • INTRODUCTION
  • GENETIC FACTORS
  • MICROCHIMERISM
  • EPIGENETIC FACTORS
  • AUTOANTIBODIES
  • EXTRINSIC FACTORS
  • Trauma
  • Radiation
  • Infections
  • Drugs
  • VASCULAR FACTORS
  • ROLE OF EPIDERMIS
  • Keratinocytes
  • Epidermal-dermal Signalling
  • THE IMMUNE RESPONSE
  • Innate Immunity
  • Acquired Immunity
  • ROLE OF MESENCHYME & FIBROBLASTS
  • ROLE OF DENDRITIC CELLS
  • ROLE OF INSULIN-LIKE GROWTH FACTOR-1 (IGF-1)
  • MORPHEA SUBTYPES AND PATHOGENESIS
  • DISTINCTIVENESS OF PATHOGENESIS OF MORPHEA IN CHILDREN
  • DIFFERENCES IN THE PATHOGENESIS OF MORPHEA AND SSC
  • REFERENCES
CHAPTER 6 HISTOPATHOLOGY
  • Muazzez Çigdem Oba and Ovgu Aydin Ulgen
  • INTRODUCTION
  • REPORTING OF THE HISTOPATHOLOGICAL FINDINGS
  • Hematoxylin and Eosin Stain (H&E)
  • Special Stains
  • Immunohistochemistry
  • Direct Immunofluorescence
  • Specific Histopathological Signs
  • HISTOLOGIC VARIANTS OF MORPHEA
  • Classical Morphea, Early Stage
  • Classical Morphea, Late Stage
  • Superficial Morphea
  • Bullous Morphea
  • CLINICAL VARIANTS OF MORPHEA WITH SPECIAL HISTOPATHOLOGICAL
  • FEATURES
  • Morphea Profunda
  • Nodular Morphea
  • En Coup De Sabre Morphea
  • Idiopathic Atrophoderma of Pasini-Pierini
  • DIFFERENTIAL DIAGNOSIS
  • REFERENCES
CHAPTER 7 CLINICAL PRESENTATION
  • Ömer Kutlu and Tasleem Arif
  • INTRODUCTION
  • CIRCUMSCRIBED MORPHEA
  • Superficial Variant of Circumscribed Morphea
  • Deep Variant of Circumscribed Morphea
  • LINEAR MORPHEA
  • The Trunk/Limb Variant
  • En Coup De Sabre
  • GENERALIZED MORPHEA
  • PANSCLEROTIC MORPHEA
  • MIXED MORPHEA
  • OTHER CLINICAL TYPES OF MORPHEA
  • Guttate Morphea
  • Keloidal morphea
  • Bullous Morphea
  • REFERENCES
CHAPTER 8 DIFFERENTIAL DIAGNOSIS
  • Shazia Jeelani and Tasleem Arif
  • INTRODUCTION
  • DIFFERENTIAL DIAGNOSIS OF GENERALISED MORPHEA
  • Systemic Sclerosis
  • DIFFERENTIAL DIAGNOSIS OF CIRCUMSCRIBED MORPHEA
  • Early Stage Circumscribed Morphea
  • Interstitial Mycosis Fungoides (IMF)
  • Acquired Port Wine Stain (APWS)
  • Granuloma Annulare (GA)
  • Subcutaneous Variant of Sweet's Syndrome
  • Interstitial Granulomatous Dermatitis (IGD)
  • Erythema Migrans
  • Erythema Nodosum Migrans
  • Annular Lichenoid Dermatitis of Youth
  • Hypertrophic Scars or Keloids
  • Connective Tissue Nevi
  • Sclerotic/Atrophic Stages
  • Idiopathic Atrophoderma of Pasini and Pierini
  • Lipodermatosclerosis (LDS)
  • Dermatofibrosarcoma Protuberans (DFSP)
  • Radiation Fibrosis Syndrome (RFS)
  • Reflex Sympathetic Dystrophy (RSD)
  • Scleromyxedema (SCX)
  • Diabetic Cheiroarthropathy
  • Carcinoid Syndrome
  • Porphyria Cutanea Tarda (PCT)
  • Nephrogenic Systemic Fibrosis (NSF)
  • Pretibial Myxedema
  • Morpheaform Basal Cell Carcinoma
  • Scleredema
  • Anetoderma
  • Stiff Skin Syndrome
  • Restrictive Dermopathy
  • DIFFERENTIAL DIAGNOSIS ACCORDING TO THE PIGMENTARY CHANGES
  • Fixed Drug Eruption (FDE)
  • Macular Lichen Planus
  • Vitiligo
  • Lichen Sclerosus
  • DIFFERENTIAL DIAGNOSIS OF LINEAR MORPHEA
  • Linear Atrophoderma of Moulin (LAM)
  • Linear Form of Cutaneous Lupus Erythematosus (CLE)
  • Melorheostosis
  • DIFFERENTIAL DIAGNOSIS OF DEEP MORPHEA
  • Subcutaneous Panniculitis-like T-cell Lymphoma
  • Lipoatrophic Panniculitis
  • Localized Lipodystrophy
  • MORPHEA AS DIFFERENTIAL DIAGNOSIS OF SYSTEMIC DISORDERS
  • Eosinophilic Fasciitis (EF)

Author

  • Tasleem Arif