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Degradation Rate of Bioresorbable Materials


Description: Bioresorbable materials could be employed to provide significant advances in drug delivery systems and medical implants. The rate of material degradation is critical to performance of both implants and the controlled release of drugs. Degradation rate of bioresorbable materials: prediction and evaluation addresses the practicalities of this subject in detail. The first section provides an overview of bioresorbable materials and the biological environment. Degradation mechanisms are reviewed in the second section in the book, followed by bioresorption test methods in the third part. The fourth section discusses factors influencing bioresorption; finally clinical applications are reviewed.


Contents:
Part 1 Introduction: An overview of bioresorbable materials
- The biological environment for bioresorbable materials.
Part 2 Degradation mechanisms: Synthetic bioresorbable polymers
- Natural bioresorbable polymers
- Bioresorbable ceramics.
Part 3 Bioresorption test methods: In-vitro physicochemical test methods to evaluate bioresorbability
- In-vitro biological test methods to evaluate bioresorbability
- In-vivo test methods to evaluate bioresorbability
- Modelling of the degradation processes for bioresorbable polymers.
Part 4 Factors influencing bioresorption: Influence of processing, sterilisation and storage on bioresorbability
- Influence of porous structure on bioresorbability: Tissue engineering scaffolds
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Part 5 Clinical application: Influence of clinical application on bioresorbability: Host response
- Scaffold and implant design: Considerations relating to characterization of biodegradibility and bioresorbability
- Drug release from bioresorbable materials.


Author Dr Fraser Buchanan is a Senior Lecturer in the School of Mechanical and Aerospace Engineering at Queens University Belfast. He is highly regarded for his expertise in developing and testing synthetic biomaterials.


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