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Delivering Drugs by Inhalation - Emerging Therapeutic Opportunities


Description: Advances in drug formulation and inhalation device design are creating new opportunities for inhaled drug delivery as an alternative to oral and parenteral delivery methods. Much of the interest in pulmonary delivery of systemic drug therapies is focused on chronic diseases and refractory conditions – aliments that require frequent drug administration for a protracted period of time. The role of device design and development in defining and driving emerging opportunities in this sector cannot be overstated. Nebulizers, metered dose inhalers (MDIs), and dry powder inhalers (DPIs) have each found a niche in the quest for optimal treatment and convenient use. While nebulizers have evolved relatively independently of the drug formulations they deliver, the current generation of MDIs and DPIs have been developed or tailored for the specific pharmaceutical being delivered, resulting in improved performance. Several of the emerging drug products covered in this report will have a significant impact in the therapeutic markets they target, improving patient compliance and effectively changing the way important illnesses and conditions are treated.

Market Data
The study presents qualitative and quantitative data and information on key market measures and benchmarks:
-Inhaled Drug Delivery Market Segment size and AGR
-Device-Pharma Alliance Activity and Deal Structure
-Inhaled Drug Economic Factors
-Strategic Positioning Factors
-Industry Structure & Competitive Landscape
-Combination Product Design Parameters
-Third-party Stakeholders Market Participant Profiles
-Market Dynamics & Sensitivities
-Competitive Risks
-Proprietary Technology Assessment
-Self-Administration Compliance Factors
-Technology Risk Factors
-Regulatory Risk Factors

Forecasts and Projections cover the Period 2008-2011

Methodology:

Research methodology is based on primary research in the form of in-depth interviews with key market participants, technology developers, distributors, industry experts, and market influencers, a list that includes regulatory officials, industry trade groups, and materials standards organizations.

Primary data is evaluated and normalized against secondary sources including trade journal articles, technical literature, industry publications, company data sheets and published information, and statistical data from government agencies and trade associations.

Forecasts and projections of market demand and future market activity are derived using standard modeling and statistical techniques


Contents: Executive Summary

Inhaled Drug Delivery Market Dynamics
- Portrait of an Evolving Market
- Established Therapeutic Targets
- Emerging Therapies
- Demographics and Growth
- Competing Technologies
- Market Drivers
- Factors Limiting Growth

Inhalation Technology
- Drug Formulations
- Inhaler Designs
- Dry Powder Inhalers
- Metered Dose Inhalers
- Nebulizers
- Performance Factors
- Bioavailability
- Dose Reproducibility
- Active Compound Stability
- Commercial Devices
- Development-Stage Devices
- Combination Products
- Emerging Device Technologies

Inhaled Drugs – Development-stage Product Candidates
- Anaphylaxis
- Cardiovascular Medicine
- Hereditary Diseases
- Immunology
- Infectious Diseases
- Metabolic
- Growth Deficiencies
- Osteoporosis
- Neurology
- Antipsychotics
- Migraine
- Parkinson’s
- Oncology
- Pain Management
- Respiratory
- Sexual Health

Market Factors
- Device Packaging
- Regulatory Issues
- Patient Compliance
- The Role of CMOs/CSOs
- Healthcare Economics

Company Profiles
- Detailed Profiles of Market Sector Participants


Companies Mentioned -3M -Akela Pharma -Alexza -Alkermes -AstraZeneca -Boehringer Ingelheim -Chiesi Farmaceutici -Direct Haler A/S -GlaxoSmithKline -Hovione -MAP Pharmaceuticals -MannKind Corporation -Meda -Microdose Technologies -Nektar Therapeutics -Novartis -Omron -Oriel Therapeutics -PARI Pharma -Respirics -Sepracor -Teva -Vectura -Viatris -YM Bioscience


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