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Drugs of Tomorrow 2000: Lung Cancer - New Partners For Old Regimens


Description: The pharmacological treatment of lung cancer has been dominated by the platinum analogs for over a decade and with no immediate replacements in sight, they are expected to play a core role in ling cancer management for the foreseeable future. However, this is not to say that the lung cancer market will stagnate over the next seven years. With the emergence of innovative, lower toxicity agents, treatment outcomes for patients with lung cancer look set to improve dramatically. With new treatments poised to take the market by storm. Drugs of Tomorrow 2000: Lung Cancer provides a detailed examination of the current lung cancer pipeline activities in 7 major pharmaceutical markets, together with in-depth analysis of the most promising classes and drugs in development to 2007 enabling you to competitively position your products, strengthen your marketing strategy and market penetration, expose potential threats to your business and target R&D resources more effectively.


Contents:
Introduction to Datamonitor


About Healthcare


TABLE OF CONTENTS


EXECUTIVE SUMMARY


Report summary


Introduction


Patient potential in lung cancer


Unmet needs in lung cancer


Investors in lung cancer


Class focus


Future market leaders


R&D opportunities in lung cancer






DISEASE OVERVIEW


Definition of lung cancer


NSCLC


SCLC



Classification of lung cancer


Disease type


Staging for lung cancer


Performance status


Age at diagnosis


Prognostic factors


Classification of pipeline products


Cytotoxic therapies: an overview


Alkylating agents


Antimetabolites


Vinka alkaloids


Other cytotoxics


Angiogenesis inhibitors


Immunotherapies


Gene therapies


Clinical endpoints in lung cancer


Survival


Toxicity


Quality of life


Response rates


Multiple end points


Unmet needs in lung cancer


Extended disease-free survival


Reduced toxicity


Metastatic disease


Second line therapy


Older patients


Screening


Prevention






LUNG CANCER PIPELINE ANALYSIS



Pipeline analysis by development strategy


Key drug discovery strategies in lung cancer


Key R&D protocol strategies in lung cancer


Key drug delivery strategies in lung cancer


Key licensing strategies in lung cancer


Pipeline analysis by class


Pipeline analysis by region


Pipeline analysis by company type


Pipeline analysis by individual company


DRUG ANALYSIS



Cytotoxics


Multitargeted antifolate (Alimta)


Tirazone (tirapazamine)


SPI-77


Troxacitabine


Pivanex


DA-125


XR5000



CP 358,774


Decitabine


ILX-295501


DX-8951f


Irofulven (MGI-114)



Angiogenesis inhibitors


Neovastat


Prinomastat


Marimastat


SU5416


Iressa



Immunotherapies


Mitumomab


rhuMAb-VEGF


SRL 172


Recombinant interferon beta


BLP25



Gene therapies


ISIS 3521


SCH 58500


RPR/INGN 201


Genasense



Others


RSR13


Incel (biricodar)



Key phase I development projects



Research developments


TheraFab


NC381


Recently discontinued projects


BMS 182751


BAY 12 9566






COMPARATIVE ANALYSIS



Comparison by class


Survival


Toxicity


Elderly patients


Refractory/relapsed disease


Marketing strength


Comparative analysis of cytotoxics


Comparison of disease-free survival in cytotoxics


Comparison of toxicity in cytotoxics


Comparison of cytotoxics in elderly patients


Comparison of cytotoxics in refractory/relapsed disease


Comparison of marketing strength in cytotoxics


Comparative analysis of antiangiogenic agents


Comparison of disease-free survival in antiangiogenic agents


Comparison of toxicity in antiangiogenic agents


Comparison of performance of antiangiogenic in elderly patients


Comparison of antiangiogenic agents in refractory/relapsed disease


Comparison of marketing strength in antiangiogenic agents


Comparative analysis of immunotherapies


Comparison of disease-free survival in immunotherapies


Comparison of toxicity in immunotherapies


Comparison of immunotherapies in elderly patients


Comparison of immunotherapies in refractory/relapsed disease


Comparison of marketing strength in immunotherapies






FUTURE FOCUS IN LUNG CANCER



Future trends in the incidence and prevalence of lung cancer


Prospective drug launches in lung cancer


Launch forecast methodology


Forecast launches in lung cancer from 2000 to 2007


Market forecasts, 2000-2007


Forecast methodology


Lung cancer market forecast, 2000-2007


Lung cancer drug class forecast, 2000- 2007


Key R&D product forecasts






APPENDIX


Clinical trial data bibliography


Forecasting drug launches


Global highest stage of development


Reclassification of development phases



List of tables


List of figures







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