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Drugs of Tomorrow 2001: Cancer Overview


Description: Drugs of Tomorrow 2001: Cancer Overview provides a comprehensive analysis of the current cancer market. The report focuses on the oncology market as a whole, looking at growth factors, class dominance and R&D focus. An in-depth analysis of the cancer pipeline by disease target examines current drugs in development and the key investors in the area for the principal tumor types (breast, brain, colorectal, head and neck, leukemia, lung, ovarian, pancreatic and prostate cancers). areas, with increasing year-on-year sales, the oncology market is becoming an increasingly important area for focus within the pharmaceutical sector. Whilst oncology does not represent the largest segment of the global pharmaceutical market, increasing incidence of the disease, combined with significant sales potential for drugs indicated for cancer ensures that it remains one of the most attractive areas for R&D investment. Cancer offers rich rewards for new and developing therapies,


Contents:
Report summary


Introduction


Future trends in the prevalence of cancer


Unmet needs in cancer


Investors in cancer


Market share


Disease and class focus


Future market leaders in cancer


R&D opportunities in cancer






CHAPTER 1 THERAPEUTIC CLASS REVIEW


Introduction


Expansion in the cancer market


Therapeutic class review


Defining the cancer market


Cytotoxic therapies


Hormonal therapies


Innovatives therapies



Adjunct therapies


Cancer market segmentation by drug class


Cytotoxics review


Hormonals review


Adjuncts review


Innovatives review


R&D spend and R&D Portfolio size


Investment in Oncology R&D


Therapeutic Focus


Investment in licensing activity in oncology R&D






PIPELINE OVERVIEW



Analysis of the cancer pipeline by drug class


Analysis of the breast cancer pipeline


Analysis of the prostate cancer pipeline


Analysis of the lung cancer pipeline


Analysis of the colorectal cancer pipeline


Analysis of the leukemia pipeline


Analysis of the ovarian cancer pipeline


Analysis of the brain cancer pipeline


Analysis of the pancreatic cancer pipeline


Analysis of the head and neck cancer pipeline






DRUG ANALYSIS



Introduction


Drugs in late stage development for breast cancer


Faslodex


IMC-C225


Gemzar


Theratope


Evista


Drugs in late stage development for prostate cancer


Cetrotide


Provenge


Abarelix


Iressa


Drugs in late stage development for lung cancer


Mitumomab


rhuMAb-VEGF


ISIS 3521


Alimta



Drugs in late stage development for colorectal cancer


Eniluracil (776C85)


SU5416


Thalomid (thalidomide)


Iressa


Gastrimmune


Rubitecan


Drugs in late stage development for leukemia


Glivec (STI 571)


Campath (alemtuzumab)


Nelarabine (GW506U78)


Rituxan (rituximab)


Drugs in late-stage development for ovarian cancer


ZD0473


Rubitecan


Taxotere


Drugs in late stage development for brain cancer


Gliadel wafer


Xcytrin


Cotara



Drugs in late stage development for pancreatic cancer


Irofulven


Avicine


Rubitecan


Drugs in late stage development for Head and Neck cancer


Photofrin


Targretin


IMC-C225


Foscan






KEY INVESTORS IN CANCER R&D


Overview


Cancer players investment in R&D


AstraZeneca


Genentech


Phamacia corporation


BMS


Schering-Plough






FUTURE FOCUS



Future trends in prevalence of cancer


Forecast methodology


Trends in the cancer market to 2007


Expansion of existing classes: cytotoxics and monoclonal antibodies


Increase in the prevalence of cancer


New drug classes: angiogenesis inhibitors and gene therapies


Global cost containment measures


Reformation of Medicare


Patent expiries


Awareness campaigns


Disease management


Increasing participation of older adults in clinical trials


Market forecasts for key cancer types


Breast cancer forecast launches and key drug sales


Forecast drug launches in breast cancer


Forecast sales of the leading pipeline drugs for breast cancer


Prostate cancer forecast launches and key drug sales


Forecast drug launches in prostate cancer






Forecast sales of the leading pipeline drugs for prostate cancer


Lung cancer forecast launches and key drug sales


Forecast drug launches in lung cancer


Forecast sales of the leading pipeline drugs for lung cancer


Colorectal cancer forecast launches and key drug sales


Forecast drug launches in colorectal cancer


Forecast sales of the leading pipeline drugs for colorectal cancer


Leukemia forecast launches and key drug sales


Forecast drug launches in leukemia



Forecast sales of the leading pipeline drugs for leukemia


Ovarian cancer forecast launches and key drug sales


Forecast drug launches in ovarian cancer


Forecast sales of the leading pipeline drugs for ovarian cancer


Brain cancer forecast launches and key drug sales


Forecast drug launches in brain cancer


Forecast sales of the leading pipeline drugs for brain cancer


Pancreatic cancer forecast launches and key drug sales


Forecast launches in pancreatic cancer


Forecast sales of the leading pipeline drugs for pancreatic cancer


Head and neck cancer forecast launches and key drug sales


Forecast launches in head and neck cancer


Forecast sales of the leading pipeline drugs for head and neck cancer






APPENDICES


Research program methodology


SPRINT databases


SPRINT R&D;


Primary Research


Quantification of Data Reliability


Strategic Issues and Opinion Surveys


References







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