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Anti-hypertensives: Patent Defense Strategies - Combating Generic Competition Through Lifecycle Management
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Description: |
It is evident that patents provide an incentive for pharmaceutical companies to invest in research and development (R&D), since they enable companies to recoup the money spent during the development and launch of a new product. However, once patents expire, generic competition tends to result in a dramatic decline in the sales of the branded product and, therefore, companies are developing increasingly sophisticated strategies for defending and competing against generic competition. This brief will focus on the effect of patent expiries, both past and future, on the anti-hypertensives market since this is the largest pharmaceutical market in terms of value and constitutes a crucial component of the portfolio of the leading cardiovascular companies. However, although the brief concentrates on the anti-hypertensives market, which is already highly genericized and currently facing another major round of patent expiries, many of the principles outlined can be applied to other markets. |
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Contents: |
EXECUTIVE SUMMARY
INTRODUCTION
THE IMPORTANCE OF LIFECYCLE MANAGEMENT
THE ANTI-HYPERTENSIVES MARKET
Overview of the market
A core component of a cardiovascular portfolio
The need for lifecycle management in the anti-hypertensives market
Recent, ongoing and future patent expiries in the anti-hypertensives market
Defending against generic competition
Planning and implementation of defense strategies
Additional indications
Competitive pricing
Launch of a generic product
New formulations
Pediatric extensions
Portfolio management
Regulatory benefits
Litigation
Case studies
Bayer's Adalat (nifedipine): a successful model of lifecycle management
Andrx's diltiazem: inventing round Cardizem's patent
Bristol-Myers Squibb's Capoten (captopril): unable to compete following patent expiry
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Anti-hypertensives: Patent Defense Strategies - Combating Generic Competition Through Lifecycle Management
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