Contents:

Brief history of the medical applications of plasticised PVC PVC-P formulation - PVC raw material -- Suspension polymerisation -- Emulsion polymerisation -- Mass or bulk polymerisation - Additives -- Plasticiser -- Other additives - PVC-P formulation -- Selection of plasticiser -- PVC-P compounding Properties of PVC-P - Mechanical properties - Low-temperature properties - Electrical properties - Surface properties - Permanence properties PVC-P as a biomaterial - Introduction - Advantages of PVC-P - Disadvantages - PVC-P as a blood-contacting biomaterial - Other applications of PVC-P as a biomaterial Blood compatibility of PVC-P - Introduction - Blood-biomaterial interactions - Factors influencing blood response to PVC-P -- PVC formulation -- Selection of plasticiser -- Plasticiser concentration -- Plasticiser surface level -- Plasticiser surface distribution -- Surface modification -- Nature of application as devices -- Blood nature and evaluation procedures - Plasticiser migration and regulation -- DEHP migration and extraction -- Toxicity of DEHP -- Alternatives to DEHP -- Alternatives to PVC-P as ablood-contacting biomaterial -- New development of PVC-P biomaterials -- Summary Modification of PVC-P surface for improved blood compatibility - Physical treatment - Chemical treatment - Biological treatment Future perspectives - Environmental and health concerns and regulatory issues -- Sterilisation - Market needs -- Market for PVC -- Market for PVC medical devices - Emerging technology

Author

Dr Xiaobin Zhao obtained his BSc in Polymer Chemistry and MSc in Biomaterial Science in Nanjing University, China and PhD in Bioengineering Unit, University of Strathclyde in Glasgow. He was an associate of Scottish Network International (SNI) and has been working in the UK biomaterial industry since 1998. Dr Zhao is the inventor of Double X-Linking Technology (DXL TM) for Mentor. He is a UK Chartered Scientist and Chemist. He is a Fellow of Royal Society of Chemistry, Professional Member of Institute of Materials in UK and Society for Biomaterial in USA. He has published more than 45 scientific papers, book chapters and gained numbers of patents on his name world widely. He holds visiting professorship in University of Strathclyde and Visiting Professorship in Lanzhou University in China. Currently he is visiting Professor in Strathclyde University and Director of UK China Research Academy of Bioactive Molecules and Materials.