Contents:

Executive Summary 1. Overview of the Global Allergy Medications Market 1.1 Allergies as a Medical Condition 1.1.1 Types of Allergies 1.1.2 Signs and Symptoms 1.1.3 Physiological Response Table 1-1. Gell & Coombs Classification of Allergic Reactions 1.1.4 Prevalence Table 1-2. Global Prevalence of Allergies 1.2 Medical Treatment of Allergies 1.2.1 Prescription Medications: Current Usage & Unmet Needs Table 1-3. Leading Prescription Allergy Medications 1.2.1.1 U.S. Table 1-4. U.S. DTC Advertising for Leading Rx and OTC Allergy Medications 2008 1.2.1.2 Europe 1.2.1.3 Japan 1.2.1.4 ROW 1.2.2 Non-Prescription Products: Current Usage & Unmet Needs Table 1-5. Leading OTC Allergy Medications 1.2.2.1 U.S. 1.2.2.2 Europe 1.2.2.3 Japan 1.2.2.4 ROW 2 Global Allergy Medications Market Forecast 2008 - 2013 2.1 Rx Allergy Medications Market 2.1.1 Rx Allergy Drug Market Forecast by Product 2.1.1.1 Growth Drivers Table 2-1. Rx Allergy Drug Market Forecast 2008 – 2013 by Product in $Million 2.1.1.2 Market Restraints Table 2-2. U.S. Patent Expirations of Leading Prescription Allergy Drugs 2.1.2 Rx Allergy Drug Market Forecast by Region Table 2-3. Rx Allergy Drug Market Forecast, 2008 – 2013 by Region in $ Million 2.1.3 Rx Allergy Drug Market Forecast by Product Class Table 2-4. Rx Allergy Drug Market Forecast, 2008 – 2013 by Product Class in $ Million Table 2-5. Rx Allergy Drug Market Product Segments Share, 2008 vs. 2013 Figure 2-1. Rx Allergy Drug Market Product Segments Share, 2008 Figure 2-2. Rx Allergy Drug Market Product Segments Share, 2013 2.2 OTC Allergy Drug Market 2.2.1 OTC Allergy Drug Market Forecast by Product Table 2-6. OTC Allergy Drug Market Forecast, 2008 – 2013 by Product in $Million 2.2.2 Growth Drivers 2.2.3 Market Restraints 2.2.4 OTC Allergy Drug Market Forecast by Region Table 2-7. OTC Allergy Drug Market Forecast, 2008 – 2013 by Region in $ Million 2.2.5 OTC Allergy Drug Market Forecast by Product Class Table 2-8. OTC Allergy Drug Market Forecast, 2008 – 2013 by Product Class in $ Million 2.3 Rx & OTC Allergy Drug Market 2.3.1 Rx & OTC Allergy Drug Market Forecast by Leading Manufacturers Table 2-9. RX & OTC Allergy Drug* Sales of Leading Manufacturers, 2008 – 2013 in $Million 2.3.2 Rx & OTC Allergy Drug Market Share of Leading Drug Manufacturers Table 2-10. Rx & OTC Market Shares of Leading Allergy Drug Manufacturers, 2008 vs. 2013 Figure 2-3. Rx & OTC Market Shares of Top Allergy Drug Manufacturers, 2008 Figure 2-4. Rx & OTC Market Shares of Top Allergy Drug Manufacturers, 2013 3. Allergy Drug Development: New Molecular Entities Table 3-1. Key Characteristics of NMEs, Generics and Indication Expansions 3.1 All Allergy Drug Developers Position 3.1.1 Challenges in Allergy Drug Development Table 3-2. All Allergy Drug Developers Product Position Overview 3.2 Key Products Under Development Figure 3-1. Allergy Compounds Tested by Phase of Development 3.2.1 Antihistamines 3.2.1.1 Physiology and Mechanism of Action 3.2.1.2 Leading Antihistamine Allergy Drug Candidates Table 3-3. Antihistamine Developers Product Position 3.2.2 Corticosteroids 3.2.2.1 Physiology and Mechanism of Action 3.2.2.2 Leading Corticosteroid Allergy Drug Candidates Table 3-4. Corticosteroid Developers Product Position 3.2.3 Mast Cell Inhibitors 3.2.3.1 Physiology and Mechanism of Action Figure 3-2. The Role of Mast Cells in Allergy Response 3.2.3.2 Leading Mast Cell Inhibitor Allergy Drug Candidates Table 3-5. Mast Cell Inhibitors Developers Product Position 3.2.4 Allergy Immunotherapy 3.2.4.1 Physiology and Mechanism of Action 3.2.4.2 Leading Immunotherapy Allergy Drug Candidates Table 3-6. Immunotherapy Developers Product Position 3.2.5 Vaccines 3.2.5.1 Physiology and Mechanism of Action Figure 3-3. Production of TH2 Cytokines 3.2.5.2 Leading Allergy Vaccine Candidates Table 3-7. Vaccine Developers Product Position 3.2.6 Other Types of Allergy Drugs 3.2.6.1 Physiology and Mechanism of Action 3.2.6.2 Other Leading Allergy Candidates Table 3-8. Other Allergy Drug Developers Product Position 3.3 Global Market Forecast for New Allergy Drugs, 2008 - 2013 3.3.1 New Allergy Drug Market Forecast: Total and Segment Market Table 3-9. Sales of New Allergy Drugs by Segment, 2008 – 2013 Figure 3-4. Market Shares of New Allergy Drugs by Segment, 2013 3.3.2 Growth Drivers 3.3.2.1 The Importance of Patents 3.3.3 Market Restraints 4. Allergy Drug Development: Indication Expansion 4.1 Indication Expansion for New Usage Table 4-1. Selected Recent Allergy Drug Indication Expansions, U.S. 4.1.1 The Economic Benefits of Indication Expansion Table 4-2. U.S. R&D Expenditure for New Medicines by the Pharma-Industry 4.1.2 Challenges in Allergy Drug Indication Expansion Figure 4-1. Cost and Time Savings of Indication Expansions 4.2 Key Products Under Development 4.2.1 Database of Allergy Indication Expansion Initiatives by Company Table 4-3. Selected Allergy Drug Indication Expansion Trials 4.2.2 Leading Areas of R&D Activity 4.2.2.1 Clarinex 4.2.2.2 Nasonex 4.2.2.3 Patanase 4.2.2.4 Singulair 4.2.2.5 Veramyst 4.2.2.6 Xolair 4.2.2.7 Xyzal 4.3 Global Market Forecast for Allergy Drug Indication Expansions Table 4-4. Sales of Allergy Drug Indication Expansions, 2008 – 2013 in $ Million Table 4-5. Product Market Share of Allergy Drug Indication Expansions, 2009 vs. 2013 Figure 4-2. Product Market Share of Allergy Drug Indication Expansions, 2009 Figure 4-3. Product Market Share of Allergy Drug Indication Expansions, 2013 4.3.1 Growth Drivers 4.3.2 Market Restraints 5. Allergy Drug Development: Basic Research 5.1 Basic Research Group & Activity Table 5-1. Leading Organizations & Details for Basic Allergy Research 5.1.1 Challenges in Basic Allergy Research Figure 5-1. National Institutes of Health Research Budget by Disease Area, Fiscal 2008 5.2 Key Areas of Investigation Table 5-2. Recent Basic Research in the Field of Allergies 5.3 Unanswered Questions 6. Strategic Alliances for Allergy Drug Development 6.1 Types of Strategic Alliances Figure 6-1. Comparison of Selected Deal Types 6.2 Current Strategic Alliances for Allergy Drug Development Table 6-1. Ongoing Strategic Alliances for Allergy Drug Development 7. Activities of the Leading Allergy Drug Developers Common Research Item: 1) Table: Product Profile: 2) R&D Strength and Capabilities 3) Marketed Allergy Drugs 4) Allergy Drug Pipeline 5) Table: Profile 7.1 Alcon Research 7.2 Allergy Therapeutics 7.3 AstraZeneca 7.4 GlaxoSmithKline 7.5 Johnson & Johnson 7.6 Meda AB 7.7 Merck 7.8 Novartis 7.9 Sanofi-Aventis 7.10 Schering-Plough 7.11 Sepracor 7.12 UCB Pharma 8. Total Allergy Drug Market: Forecasts & Directions Table 8-1. Total Allergy Drug Sales by Segment, 2008 – 2013 in $Million Figure 8-1. Total Allergy Drug Sales Growth by Segment, 2008 – 2013 Figure 8-2. Allergy Drug Market Share by Segment, 2008 Figure 8-3. Allergy Drug Market Share by Segment, 2013 9. Other Top Companies with Allergy Projects Table 9-1. Other Top Companies with Late Stage Allergy Projects Table 9-2. Other Top Companies with Early Stage Allergy Projects 10. Database of Allergy Drug Developers