This research study is about drug delivery systems. It provides readers with relevant information, insights and analysis. This important medical opportunity is assessed in terms of technical and business areas. The participating companies are mapped to show where they fit in the industry landscape. This study reviews the kinds of drug delivery systems that are being used by pharma, biotech or medical device companies.
The report discusses the broad range of drug delivery systems, the technical advances and the applications that drug makers might use. Key advances include orally dissolving tablets and filmstrips, needle- and needle-free injection systems, transdermal patches, transmucosal delivery, RNAi, drug-coated stents, PEG, nanotechnology, liposomes, monoclonal antibodies, gene delivery, and implants, which all contribute to the many ways that drugs or therapies can be delivered. Drug delivery systems are reviewed in terms of approaches used for delivering drugs targeting major diseases including cardiovascular, cancer, asthma, diabetes, and the central nervous system among others.
This market study shows that drug delivery technologies can help drug makers overcome some of their big challenges. The drug industry continues to see the commercial demise of major branded drugs that reach their patent expiration date. Billions of dollars in revenues are lost to generic drug makers each year. The technology can be used as part of a ‘line extension’ strategy to extend the commercial life of their profitable products. Drug delivery can help ‘rescue’ drug projects with technical challenges by using a customized delivery system.
This report discusses the above topics with interesting and useful findings. The study estimates that the US drug delivery market value might reach nearly $85 billion by 2010. The research includes over 235 key alliances and M&As through 2006. This study uses 29 figures and tables to illustrate the findings or trends. The profiles about companies important to the expanding drug delivery market include detailed information about their business and technical activities.
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About This Report
Drug Delivery Systems: Some Definitions
Drug Delivery Systems: What They Can Do
Highlights of Pharma Issues Driving the Need for Drug
Declining Pharmaceutical Industry Productivity
Patent Expirations and Declining Branded Drug Sales
Pharmas Use Patent Extension Strategies
Many Pharmas Will Seek Partners for Drug Delivery
New Crop of Drugs Will Reach the Market in Near
Limited Pharma Resources: Its Difficult to Invent
Every Drug Needs a Drug Delivery System
Key Motivators for Developing Drug Delivery Systems
Genomics, Proteomics and Targeted Therapies
Protein and Peptide Drugs
Expanding Knowledge About Disease Mechanisms
Commercial and Technical Challenges of Drug Delivery
Market is Diverse and Dynamic
An Expanding Industry
Companies Migrating to Become Specialty or Generic
A Market Snapshot
The Pharma Industry Wants Drug Delivery Systems
Changing Business Models
2.Drug Delivery Technology Developments
Delivery by Controlled Release Approaches
Oral Drug Delivery
New Formulations and Packaging
Orally Disintegrating Tablets (ODTs)
Orally Disintegrating Film Strips (ODFs)
Enhancing Drug Bioavailability or Solubility
Injection Drug Delivery
Drug Delivery by Implantable Infusion Pump
Drug Delivery to Specific Organs
Lung Drug Delivery
Drug Delivery via the Nose
Delivery to the Cardiovascular System
Delivery to the Gastrointestinal Tract
Delivery to the Urogenital Tract
Drug Delivery into the Eye
Drug Delivery by Transdermal Methods
Drug Delivery to Mucosal Membranes
Targeting Selected Disease Sites
Drug Delivery by Polymers and Proteins
Drug Delivery by Small Particles
Drug Delivery by Liposomes
Drug Delivery by Heat-Activated Liposomes
Drug Delivery by Microparticles
Drug Delivery by Modified Blood Cells
Drug Delivery by Nanoparticles
Viral Vectors for Gene Delivery
Non-Viral Vectors for Gene Delivery
3.Survey of Changing DDS Developments
Protein Drug Delivery
Developments in Polyethylene Glycol (PEG)
Drug Delivery to the Eye
Analyst Opinion: Next Generation Companies
4.Recent Strategic Alliances and M&As
Alliance Analysis: Deals Through 2006
Summaries of Drug Delivery Alliance Deals
5.Drug Delivery Systems Market Forecast
The US Drug Delivery Market
A Large Market
New Innovations Help Drugs Work Better
Demand for Less Invasive Drugs and Treatments
Pharmaceutical Firms Can Differentiate Products
The US Drug Delivery Market, 2005-2010E
Market Segments Defined by Route of Administration
Oral Delivery Segment
Injectable Delivery Segment
Injection Devices Delivery Segment
Inhaled Delivery Segment
Inhaler Devices Segment
Transdermal Delivery Segment
Implant Delivery Segment
Transmucosal Delivery Segment
Therapeutic Antibodies Segment
Therapeutic & Cancer Vaccine Segment
Targeted Therapy/Delivery Segment
Other Delivery Segment
Market Shares of the US Drug Delivery Market, 2005
Market Map: DDS Companies by Technology Categories
6.Patent Litigation Examples
University of Alabama v. Nektar Therapeutics
IVAX, Teva Pharmaceutical Industries Ltd., et al v.
Johnson & Johnson v. Boston Scientific
Chiron Corporation v. Corus Pharma, Inc.
Novartis Pharmaceuticals Corp., et al v. Sun
Pharmaceutical Industries Ltd.
GlaxoSmithKline Plc v. Par Pharmaceutical Companies,
Inc. (Kali Laboratories, Inc.)
Santarus, Inc. v. TAP Pharmaceutical Products, Inc.
Travanti Pharma Inc. v. IOMED
7.Drug Delivery With Nanotechnology
Companies Using Nanotechnology for Drug Delivery
Selected Nanotech R&D Companies
Activities of Selected Drug Delivery Companies
Abgenix, Inc. (Amgen)
Alnylam Pharmaceuticals, Inc.
Cima Laboratories (Cephalon)
NanoMed Pharmaceuticals, Inc.
Nastech Pharmaceutical Company, Inc.
Noven Pharmaceuticals, Inc.
Palatin Technologies, Inc.
Raven Biotechnologies, Inc.
Sanofi Pasteur SA (Vaccines)
Sirna Therapeutics, Inc.
Sontra Medical Corporation
Watson Pharmaceuticals, Inc.
Appendix A: Top Drug Delivery Companies
Appendix B: Drug Delivery Industry Websites
Pharmaceutical Industry Sites
Government Office Sites
Industry News Sites
Appendix C: Glossary of Terms
About the Publisher and Authors
About Takeda Pacific
About the Authors
List of Tables
Table 1. Drug Delivery Systems Market in US, 2005-2010
Table 2. Survey Results: Emerging Drug Delivery
Table 3. Previous Survey Results: Top New DDS Technologies
Table 4. DDS Technology Review
Table 5. Strategic Alliance and M&A Analysis, 2004 through
Table 6. Alliances in 2006
Table 7. Alliances in 2005
Table 8. Alliances in 2004
Table 9. Drug Delivery Market in the US by Segments, 2005-
Table 10. US DDS Market Revenues by Share, 2005 and 2010E
Table 11. Competing DDS Companies by Technology Categories
Table 12. Examples of Drug Delivery Litigations
Table 13. Drug Delivery Companies Using Nanotechnology
Table 14. The Top Drug Delivery Companies by Total Revenues
List of Illustrations
Figure 1. Drug Delivery Systems Market in the US, 2005-2010
Figure 2. Controlled Release Drug Delivery System
Figure 3. The Oral Drug Delivery Route
Figure 4. Products Featuring Orally Disintegrating Film
Figure 5. Injection Drug Delivery by Needle Size
Figure 6. Implantable Insulin Delivery System
Figure 7. Inserting a Needle for Bone Marrow Infusion
Figure 8. Airway Delivery by Nektar
Figure 9. Close-up of Drug Delivery Mechanism to the Lung
Figure 10. Two Leading Drug-Coated Stents
Figure 11. Urogenital Drug Delivery For Men
Figure 12. Drug Delivery Mechanism for a Transdermal Patch
Figure 13. The DOT Matrix Patch by Noven
Figure 14. Drug Delivery Market in the US by Segments, 2005-
Figure 15. US DDS Market Revenues by Share, 2005 and 2010E
-Abgenix, Inc. (Amgen)
-Alnylam Pharmaceuticals, Inc.
-Cima Laboratories (Cephalon)
-NanoMed Pharmaceuticals, Inc.
-Nastech Pharmaceutical Company, Inc.
-Noven Pharmaceuticals, Inc.
-Palatin Technologies, Inc.
-Raven Biotechnologies, Inc.
-Sanofi Pasteur SA (Vaccines)
-Sirna Therapeutics, Inc.
-Sontra Medical Corporation
-Watson Pharmaceuticals, Inc.