|
|
 |
|
Viewing report
|
|
|
|
Nuclear Receptors: Key Targets for New Pharmaceuticals
Drug and Market Development Publishing, Oct 2003, Pages: 160
The current market for nuclear receptor targeted drugs is estimated to be 10-15% of the $400 billion global pharmaceutical market.
Nuclear receptors are a family of proteins involved in key metabolic processes with great potential as targets for the treatment of significant diseases such as cancer, coronary heart disease, and diabetes. Collectively these diseases represent a large market for prescription drugs worldwide. The nuclear receptor family contains a large group of transcription factors, with 49 members presently identified in the human genome. Nuclear receptors are attractive targets for drug discovery because those that have been discovered thus far have proved to be 'druggable', in other words, their activity can be modulated by small molecules.
The contents of this report are as follows:
This Nuclear Receptors Market Analysis Report describes the key members of the nuclear receptor family and discusses their potential as drug targets. In addition, the Report provides an overview of nuclear receptor physiology, highlighting the potential of each receptor as a target for pharmaceutical development
Market Opportunities
-Development of a new generation of nuclear receptor targeting drugs using the information gained from this large family of transcription factors.
- Targeting underserved markets through the development of pharmaceuticals that change the activity of orphan receptors.
- Development of highly selective therapeutics designed to alter the tissue specific expression of nuclear receptor regulated genes.
Key Reasons to Buy this report:
- Discover the commercial potential of nuclear receptors through an assessment of the current and potential market for drugs targeting major diseases such as cancer, diabetes, and obesity.
- Gain an understanding of nuclear receptor controlled pathways and how the modulation of these pathways forms a target for rational drug design with an overview of what is known about each receptor and how they impact disease processes.
- Discover the impact of nuclear receptors on drug development via an in-depth analysis of recent discoveries and applications.
- Learn about the potential of nuclear receptors as drug targets from reliable and thought-provoking interviews with authorities involved in this industry.
- Focus on the primary companies engaged in nuclear receptors with in-depth profiles of their technologies, financial and partnering activities, pipelines, and more.
Customers who bought this item also bought
Novel Targets in Drug Discovery
Transmembrane Transporters: High Sales, High Potential as Drug Targets
Kinases: Advanced Strategies and Multiple Targets for Drug Discovery
Preclinical Cancer Therapeutics 2007: Decoding Next Generation Drug Targets for Market Success
Proteases as Drug Targets: Technologies and Opportunities for Drug Discovery
Patents in the Postgenomic Era: Proprietary Drug Targets and Therapies
Rheumatoid arthritis: Emerging drug discovery targets and therapeutic candidates
Phosphatases: Emerging Role in Signal Transduction, Human Therapeutics, & As Drug Targets
|
|
|
|
