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On-Chip Pretreatment of Whole Blood by Using MEMS Technology - Product Image

On-Chip Pretreatment of Whole Blood by Using MEMS Technology

  • Published: January 2012
  • Region: Global
  • Bentham Science Publishers Ltd

Microfabrication technology has stimulated a plurality of lab-on-a-chip research and development efforts aimed at enabling biomedical researchers and health care practitioners to manipulate and analyze complex biological fluids at the nano and microliter scale. On-chip pretreatment of whole blood is one of the hottest topics in lab-on-a-chip research since whole blood has been regarded as the most important clinical sample. Various microfluidic chips for blood sample pretreatment, such as plasma isolation, cells separation, cells lysis, gene or protein purification, etc., are described in this e-book. These microchips are designed and fabricated by MEMS technology. Original clinical samples, such as whole blood, which could be directly pre-treated on the microfluidic chips, can increase diagnostic capacity significantly by enabling rapid, point-of-care chemical analysis requiring only nanoliter sample and reagent volumes, thereby reducing cost and turn-around time. This e-book is a valuable reference for readers interested in this specific clinical application of advanced MEMS technology.

Foreword i
Preface ii
List of Contributors iii
CHAPTERS
1. Introduction of Microfluidic Chips Targeting Whole Blood Pretreatment 3
Xing Chen, Dafu Cui and Jian Chen
2. Microfluidic Chips for Plasma Isolation from Whole Blood 8
Xing Chen, Dafu Cui and Jian Chen
3. Microfluidic Chips for Blood Cell Separation 30
Xing Chen, Dafu Cui and Jian Chen
4. Microfluidic Devices Targeting Blood Cell Lysis 64
Xing Chen, Dafu Cui and Jian Chen
5. Microfluidic Chips for DNA Extraction and Purification 84
Xing Chen, Dafu Cui and Jian Chen
6. Integrated Microfluidic Chips for Whole Blood Pretreatment 110
Xing Chen, Dafu Cui and Jian Chen
Index 117

Editor: Xing Chen

Note: Product cover images may vary from those shown

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