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Strategic Development of Neural Stem & Progenitor Cell Products - 2013 Update Product Image

Strategic Development of Neural Stem & Progenitor Cell Products - 2013 Update

  • ID: 698314
  • November 2013
  • Region: Global
  • 113 Pages
  • BioInformant

Neurogenesis is the process by which neurons are created. This process is most active during pre-natal development when neurogenesis is responsible for populating the growing brain. Neural stem cells (NSCs) are the self-renewing, multipotent cells that differentiate into the main phenotypes of the nervous system. These cell types include neurons, astrocytes, and oligodendrocytes. Neural progenitor cells (NPCs) are the progeny of stem cell division that normally undergo a limited number of replication cycles in vivo.

The terms neuronal and neural also need to be defined. Technically speaking, “neuronal” means “pertaining to neurons," and “neural” means “pertaining to nerves, which are the cordlike bundles of fibers made up of neurons.” Since both terms ultimately are descriptive of neurons, the scientific community uses the terms "neuronal" and "neural" interchangeably. The complexity of this issue is explored from a strategic perspective within this report.

In particular, when naming products, companies are advised to use the term “neural” rather than “neuronal,” both in reference to stem cells and progenitor READ MORE >

I. BACKGROUND

A. Language and Definitions
1. Neurogenesis
2. Neuronal vs. Neural
3. Neural Stem Cells vs. Neural Progenitor Cells
B. Brief History
C. Regulation of Neural Stem & Progenitor Cells
1. In vitro Regulation
2. In vivo Regulation
D. Product Background

II. APPLICATIONS

A. Basic Research
1. Developmental Biology
2. Adult Biology
B. Drug Discovery Applications
C. Drug Delivery Applications
D. Neural Toxicology Assessment
E. Neural Transplantation
F. Brain Tumor Research

III. APPLICATION PRIORITIES

A. Overall
1. Cell-Based Therapies
2. Standardized Neural Toxicology Assays
B. Breakdown of Neural Stem Cell Research by Disorder
C. By Segment
1. Academic
2. Biotech
3. Pharma

IV. PATENTS

A. Key Neural Stem and Progenitor Cell Patents
B. Additional US Patents
C Additional European Patents

V. MARKET TREND ANALYSIS

A. Clinical Trial Analysis
1. Frequency by Year
2. Geographical Breakdown
B. Grant Rate Analysis
1. Historical Analysis
2. Future 5-Year Projection
C. Patent Rate Analysis
D. Scientific Publication Rate Analysis
1. Historical Data
2. Future 5-Year Projections
3. NSC Research Frequency Relative to Other Stem Cell Types
E. Geographical Analysis: Domestic vs. International Status
1. Number of NSC Labs, by Region of World
2. Percent of Total NSC-Specific Research Funding, by Region of World

VI. MARKET SIZE

A. Definition: NSC Product Market
B. Experimental Approach
C. NSC Research Products
1. Market Size
2. 5-Year Market Projections
D. NSC Therapy Market
1. Market Size
2. 5-Year Market Projections

VII. COMPETITORS: LEADING SUPPLIERS OF NEURAL STEM CELL PRODUCTS

A. EMD Millipore
B. STEMCELL Technologies
C. AlphaGenix, Inc.
D. R&D Systems
E. Cell Applications
F. SA Biosciences
G. ScienCell
H. Neuromics
I. Amaxa
J. Life Technologies
K. Sigma Aldrich
L. StemCells, Inc.
M. Lonza
N. BD Biosciences

VIII. LEADING PHARMACEUTICAL COMPANIES DEVELOPING NEURAL STEM CELL THERAPIES

A. Neuralstem, Inc
B. NeuroNova AB
C. NeuroGeneration

IX. BREAKDOWN OF STEM CELL RESEARCH ACTIVITY BY CELL TYPE

X. POTENTIAL END-USERS OF NEURAL STEM CELL PRODUCTS

A. Academic Labs
B. Private Labs
C. Commercial Labs
D. Government Labs

XI. PRODUCT IDEAS & SUGGESTIONS

A. Product Categories
1. Neural Stem Cell Lines & Neural Tissues
2. Neural Stem Cell Kits
3. Media: Maintenance, Differentiation, Expansion, & Freezing Medium
4. Growth Factors
5. Markers for Neural Stem Cells & Differentiated Progeny
6. PCR Arrays
7. Nucleofection Tools
8. Neural Toxicity Assessment
B. Product Suggestions
1. Neural Toxicity Assessment Products
2. Species-Specific Opportunities
3. Areas of Underdeveloped Competition
4. NSCs Derived from Novel Sources
5. Novelty Cells Types, such as Neural Rosette Cells (R-NSCs)

XII. SCIENTIST PANEL: DETAILED END-USER SURVEY

A. Survey Overview
B. Characterization of Market Survey Respondents
1. Geographic Distribution of Respondents
2. Respondent Breakdown by Industry Affiliation
3. Breakdown of Respondents by Duration of NSC Research Activity
C. Survey Findings
1. General Scope
2. Comparison of Providers / Brand Preferences
3. Marketing Assessment
D. Terms Used in Online Product Search

XIII. CONCLUSIONS

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