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R&D Productivity - The State of Research and Development in the Biopharmaceutical Industry Product Image

R&D Productivity - The State of Research and Development in the Biopharmaceutical Industry

  • Published: April 2013
  • Region: Global
  • 71 Pages
  • CBR Pharma Insights

As blockbusters go off patent and the pool of marketed products supporting pharmaceutical Research & Development (R&D) decline, questions about the future of R&D in the pharmaceutical and biotech industry arise. Where will funding come from? Is spend decreasing? If spend is decreasing, what impact is this having on R&D? What can be done to encourage innovation in the biotech and pharmaceutical industry? Is the biotech model of R&D better for innovation than the traditional pharmaceutical model?

Gauging the overall growth of R&D in the pharmaceutical and biotech industry proves challenging in regards to stipulating the appropriate definition of variables by which this is measured. Public companies may release overall expenses, yet allocations to specific products or franchises may be more difficult to assess. On a related note, information may be available about specific research projects and molecules under development, yet tying those back to the overall R&D expenses can also be challenging. To that end, we are focused on general estimations in this report which address a high level analysis of the overall industry and a basic formulaic approach to READ MORE >

1. Executive Summary

2. Current Picture of Research and Development
- Key issues affecting the industry’s R&D efforts
- A review of the industry pipeline
- - Near term and future outlook
- Pipeline by phase of development
- - Is the industry pipeline addressing global needs?
- Pipeline by therapeutic area and, more specifically, indication
- - The convergence of Biotechnology and Pharmaceuticals to Biopharmaceuticals
- Pipeline’s molecule mix
- Do traditional pharmaceutical companies still exist?
- - Status of Top companies
- Approvals by year and by sponsor (Established vs. Emerging companies)
- Trends in R&D spend
- - Is R&D spend decreasing?
- Review of Top companies R&D spend
- - R&D spend by phase of development
- Probability of success rates on several levels: overall clinical approval, phase transition, and therapeutic area.
- - How have overall clinical approval rates changed over time?

3. R&D Productivity
- Components of R&D productivity: efficiency and effectiveness
- Variables that influence productivity
- Industry efforts to improve productivity
- - Collaboration
- Companies are going beyond their own four walls to cut costs, mitigate risk, and inspire innovation.
- - Outsourcing
- CROs take on a greater role
- - Consideration of Key Stakeholders
- What roles do Physicians, Payers, Patients, and Shareholders play in R&D?
- - Innovation
- Featuring Biotech Incubators

4. Company Pipeline Snapshots (15 companies included)
- Pipeline views on a company by company basis.
- - Views may include core therapeutic areas, compound origination, molecule type, and new molecular entities.
- Trends in R&D spend

5. References

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