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In-Vitro Toxicology/ Toxicity Testing Market by Industry, Technology, Applications & Method - Global Forecast to 2018 - Product Image Special Offer Sale Banner

In-Vitro Toxicology/ Toxicity Testing Market by Industry, Technology, Applications & Method - Global Forecast to 2018

  • Published: April 2014
  • Region: Global
  • 246 Pages
  • Markets and Markets
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The global in-vitro toxicology testing market is estimated to reach $17,227 million by 2018 at a CAGR of 13.5% during the forecast period 2013–2018.

FEATURED COMPANIES

  • Alere, Inc.
  • Bioreliance, Inc.
  • Catalent
  • Covance, Inc.
  • Cyprotex
  • Eurofins Scientific
  • MORE

'In-Vitro Toxicology/ Toxicity Testing Market by Industry (Diagnostic, Pharmaceutical, Cosmetics, Chemical), Technology (Cell Culture, HTS, Omics), Applications (Systemic, Dermal, Ocular), Method (Cellular Assay, Ex vivo, In Silico) - Global Forecast to 2018'

Attributed to the support offered by the European government, the in vitro toxicology testing market in Europe was the largest in 2013 and is expected to hold the same stance by 2018.

There has been a substantial rise in the costs to develop a new pharmaceutical product in recent years. This is specially observed when a new compound enters animal testing and clinical trials. The use of animals in experimentation is becoming dearer, primarily due to the costs involved in breeding and acquisition of animals, due to the complexity of procedures involved in the in vivo testing, and several other ethical issues including concerns for animal welfare. Moreover the rates of drug attrition have also risen in recent years due to lesser availability of data on the toxicity profiles of the candidates that are under development process.

To counteract these issues there has been a rise in the development of in vitro methods READ MORE >

1 Introduction
1.1 Objectives Of The Study
1.2 Report Description
1.3 Markets Covered
1.4 Stakeholders
1.5 Market Scope
1.6 Research Methodology
1.6.1 Market Size Estimation & Data Triangulation
1.6.2 Key Data Points From Secondary Sources
1.6.3 Key Data Points From Primary Sources
1.6.4 Assumptions

2 Executive Summary

3 Premium Insights
3.1 Market Size
3.2 Market Dynamics
3.3 In-Vitro Toxicity Testing Market Size Snapshot
3.4 In-Vitro Toxicity Testing, Geographic Analysis By Industry
3.5 In-Vitro Toxicity Testing Market Size, By Technology
3.6 In-Vitro Toxicity Testing Market Size, By Method
3.7 In-Vitro Toxicity Testing Market, By Application

4 Market Overview
4.1 Introduction
4.2 Market Segmentation
4.3 Market Dynamics
4.3.1 Drivers
4.3.1.1 Dearth Of Publicly Accessible Databases to Facilitate The Use Of In Vitro Test Methods
4.3.1.2 New and Promising Technologies to Propel Market
4.3.1.3 Technological Advancements and Shifting Focus to Innovative Approaches Of 3d Cell Cultures Are Driving The Cell Culture Technology Market
4.3.1.4 Opposition to Animal Testing Will Help Shift The Focus to In Vitro Testing
4.3.2 Restraints
4.3.2.1 Technological Disadvantages Associated With In Vitro Tests Limit Their Use
4.3.2.2 In Vitro Models Cannot Detect Autoimmunity and Immunostimulation
4.3.2.3 Predictive Ability Of In Vitro Testing Leads to Decreasing Adoption Of These Tests
4.3.3 Opportunities
4.3.3.1 The Toxicology In The 21st Century (Tox21) Program
4.3.3.2 Increasing Drug Discovery and Innovation and Modernization in The Market
4.3.3.3 Growing Demand For In Vitro Toxicology in The European Market
4.3.4 Threats
4.3.4.1 Reluctance Of Regulatory Authorities to Consider Alternate Methods For Proving Safety and Efficacy
4.4 Burning Issues
4.4.1 Validation Of New In Vitro Methods
4.4.2 Differences in Opinion Between The U.S. and Eu Regulatory Authorities
4.5 Winning Imperatives
4.5.1 3d Human Hepatocyte Models to Boost The In Vitro Testing Market

5 By Industry
5.1 Introduction
5.2 Diagnostics
5.2.1 Diagnostics, By Type
5.2.1.1 Forensics
5.2.1.2 Drug Abuse & Workplace Drug Testing
5.2.2 Diagnostics, By Sample
5.2.2.1 Urine Screening
5.2.2.2 Alcohol Screening
5.2.2.3 Oral Fluid Screening
5.2.2.4 Hair Screening
5.2.2.5 Others
5.3 Cosmetics & Household Products
5.4 Pharmaceutical Industry
5.5 Chemicals Industry
5.6 Food Industry

6 By Technology
6.1 Introduction
6.1.1 Cell Culture Technology
6.1.1.1 Primary Monolayer and Three-Dimensional Cell Cultures
6.1.2 High Throughput Technologies
6.1.2.1 High Throughput Toxicity Testing
6.1.2.2 The Epa Toxcast Program
6.1.3 Molecular Imaging Technologies
6.1.3.1 Molecular Imaging Technologies
6.1.3.2 High Content Imaging Technologies
6.1.4 Omics Technologies
6.1.4.1 Genomics
6.1.4.2 Toxicogenomics
6.1.4.3 Proteomics
6.1.4.4 Metabolomics

7 By Application
7.1 Introduction
7.2 Systemic Toxicity
7.3 Dermal Toxicity
7.4 Ocular Toxicity
7.5 Endocrine Disruption (Reproductive/Developmental Toxicity)
7.6 Others (Admet, Organ-Specific Toxicity, Drug-Drug Interactions, Target/Pathway Assays, & Ecotoxicity)
7.6.1 Admet (Pharmacokinetics & Metabolism Testing)
7.6.2 Organ-Specific Toxicity
7.6.3 Drug-Drug Interactions
7.6.4 Target/Pathway Assays
7.6.5 Ecotoxicity

8 By Method
8.1 Introduction
8.2 Cellular Assays
8.3 Biochemical Assays
8.4 In Silico Methods
8.5 Ex Vivo Models

9 Geographic Analysis
9.1 Introduction
9.2 Europe
9.3 North America
9.4 Asia
9.5 Rest Of The World (ROW)

10 Competitive Landscape
10.1 Introduction
10.2 Competitive Landscape, 2011-March 2014
10.3 New Product Launches
10.4 Mergers & Acquisitions
10.5 Agreements, Partnerships & Collaborations
10.6 Expansions
10.7 Other Developments

11 Company Profiles (Business Overview, Products & Services, Key Strategy, Recent Developments, Mnm View)*
11.1 Agilent Technologies, Inc.
11.2 Alere, Inc.
11.3 Bio-Rad Laboratories, Inc.
11.4 Bioreliance, Inc. (A Subsidiary Of Sigma-Aldrich Corporation)
11.5 Catalent
11.6 Charles River Laboratories International, Inc.
11.7 Covance, Inc.
11.8 Cyprotex
11.9 Eurofins Scientific
11.1 GE Healthcare
11.11 Life Technologies Corporation (Thermo Fisher Scientific)
11.12 Quest Diagnostics

*Details On Products & Services, Key Strategy, & Recent Developments Might Not Be Captured in Case Of Unlisted Companies.

List Of Tables

Table 1 In-Vitro Toxicology/Toxicity Testing, By Geography, 2011-2013 ($Million)
Table 2 Global Market, By Industry, 2011–2018 ($Million)
Table 3 Global Market For Diagnostics Industry, By Type, 2011–2018 ($Million)
Table 4 In Vitro Toxicology Testing Market For Diagnostics Industry, By Geography, 2011–2018 ($Million)
Table 5 Market For Forensics, By Geography, 2011–2018 ($Million)
Table 6 Market For Drug Abuse & Workplace Drug Testing, By Geography, 2011–2018 ($Million)
Table 7 Market For Diagnostics Industry, By Sample, 2011–2018 ($Million)
Table 8 Urine Sample Testing Market, By Geography, 2011–2018 ($Million)
Table 9 Alcohol Sample Testing Market, By Geography, 2011–2018 ($Million)
Table 10 Oral Sample Testing Market, By Geography, 2011–2018 ($Million)
Table 11 Hair Sample Testing Market, By Geography, 2011–2018 ($Million)
Table 12 Others Sample Testing Market, By Geography, 2011–2018 ($Million)
Table 13 In Vitro Toxicology Testing Market For Cosmetics & Household Industry, By Geography, 2011–2018 ($Million)
Table 14 In Vitro Toxicology Testing Market For Pharmaceutical Industry, By Geography, 2011–2018 ($Million)
Table 15 In Vitro Toxicology Testing Market For Chemical Industry, By Geography, 2011–2018 ($Million)
Table 16 Market For Food Industry, By Geography, 2011–2018 ($Million)
Table 17 Global In Vitro Toxicology Testing Market, By Technology, 2011–2018 ($Million)
Table 18 Market For Cell Culture Technology, By Geography, 2011–2018 ($Million)
Table 19 Global Market For Cell Culture Technology, By Industry, 2011–2018 ($Million)
Table 20 In Vitro Toxicology Testing Market For High Throughput Technology, By Geography, 2011–2018 ($Million)
Table 21 Global Market For High Throughput Technology, By Industry, 2011–2018 ($Million)
Table 22 Market For Molecular Imaging Technology, By Geography, 2011–2018 ($Million)
Table 23 Global Market For Molecular Imaging Technology, By Industry, 2011–2018 ($Million)
Table 24 Market For Omics Technologies, By Geography, 2011–2018 ($Million)
Table 25 Global Market For Omics Technologies, By Industry, 2011–2018 ($Million)
Table 26 Global Market, By Application, 2011–2018 ($Million)
Table 27 In Vitro Toxicity Testing Market For Systemic Toxicology, By Geography, 2011–2018 ($Million)
Table 28 Market For Dermal Toxicology, By Geography, 2011–2018 ($ Million)
Table 29 Market For Ocular Toxicology, By Geography, 2011–2018 ($Million)
Table 30 Market For Endocrine Disruption, By Geography, 2011–2018 ($Million)
Table 31 Market For Other Applications, By Geography, 2011–2018 ($Million)
Table 32 Market, By Method, 2011–2018 ($Million)
Table 33 Primary Cell Culture Advantages & Limitations
Table 34 In Vitro Toxicity Testing Market For Cellular Assays, By Geography, 2011–2018 ($Million)
Table 35 In Vitro Toxicity Testing Market For Biochemical Assays, By Geography, 2011–2018 ($Million)
Table 36 In Vitro Toxicity Testing Market For In Silico Methods, By Geography, 2011–2018 ($Million)
Table 37 In Vitro Toxicity Testing Market For Ex Vivo Methods, By Geography, 2011–2018 ($Million)
Table 38 In Vitro Toxicology Market, By Geography, 2011–2018 ($Million)
Table 39 Europe: Market, By Industry, 2011–2018 ($Million)
Table 40 Europe: Market For Diagnostics Industry, By Sample, 2011–2018 ($Million)
Table 41 Europe: Market For Diagnostics Industry, By Type, 2011–2018 ($Million)
Table 42 Europe: Market, By Technology, 2011–2018 ($Million)
Table 43 Europe: Market, By Method, 2011–2018 ($Million)
Table 44 Europe: Market, By Application, 2011–2018 ($Million)
Table 45 North America: Market, By Industry, 2011–2018 ($Million)
Table 46 North America: Market For Diagnostics Industry, By Sample, 2011–2018 ($Million)
Table 47 North America: In Vitro Toxicology Testing Market For Diagnostics Industry, By Type, 2011–2018 ($Million)
Table 48 North America: Market, By Technology, 2011–2018 ($Million)
Table 49 North America: Market, By Method, 2011–2018 ($Million)
Table 50 North America: Market, By Application, 2011–2018 ($Million)
Table 51 Asia: Market, By Industry, 2011–2018 ($Million)
Table 52 Asia: Market For Diagnostics Industry, By Sample, 2011–2018 ($Million)
Table 53 Asia: Market For Diagnostics Industry, By Type, 2011–2018 ($Million)
Table 54 Asia: Market, By Technology, 2011–2018 ($Million)
Table 55 Asia: Market, By Method, 2011–2018 ($Million)
Table 56 Asia: Market, By Application, 2011–2018 ($Million)
Table 57 ROW: Market, By Industry, 2011–2018 ($Million)
Table 58 ROW: Market For Diagnostics Industry, By Sample, 2011–2018 ($Million)
Table 59 ROW: Market For Diagnostics Industry, By Type, 2011–2018 ($Million)
Table 60 ROW: Market, By Technology, 2011–2018 ($Million)
Table 61 ROW: Market, By Method, 2011–2018 ($Million)
Table 62 ROW: Market, By Application, 2011–2018 ($Million)
Table 63 New Product Launches, 2011–2014
Table 64 Mergers & Acquisitions, 2011–2014
Table 65 Agreements, Partnerships, & Collaborations, 2011–2014
Table 66 Expansions, 2011–2014
Table 67 Other Developments, 2011–2014

List Of Figures

Figure 1 Market Crackdown & Data Triangulation
Figure 2 Market Forecasting Model
Figure 3 In Vitro Toxicology Testing, By Industry, 2013 ($Million)
Figure 4 Global Market, By Technology, 2013 ($Million)
Figure 5 Market Size, ($Million)
Figure 6 Market Dynamics
Figure 7 Market Size Snapshot, 2013 ($Million)
Figure 8 Geographic Analysis, By Industry, 2013 ($Million)
Figure 9 Global Market Size, By Technology, 2013 ($Million)
Figure 10 Global Market Size, By Method, 2013 ($Million)
Figure 11 Opportunity Matrix: Global Market, By Application, 2013
Figure 12 Market Crackdown & Data Triangulation
Figure 13 Global Market, By Industry,2013 ($Million)
Figure 14 Global Market, By Technology, 2013 Vs 2018 ($Million)
Figure 15 Primary Cell Cultures Advantages & Disadvantages
Figure 16 High Throughput Technology Advantages & Disadvantages
Figure 17 Molecular Imaging Technologies Advantages & Disadvantages
Figure 18 High Content Imaging Technologies Advantages & Disadvantages
Figure 19 Genomics Advantages & Disadvantages
Figure 20 Proteomics Advantages & Disadvantages
Figure 21 Metabolomics Advantages & Disadvantages
Figure 22 Global Market, By Application, 2013 ($Million)
Figure 23 Opportunity Matrix: Global Market, By Method, 2013
Figure 24 In Vitro Toxicology Testing Market, By Geography, 2013
Figure 25 Key Growth Strategies, 2011–March 2014

The global market of in-vitro toxicology testing is subdivided into industry, technology, method, application and geography. On the basis of industry, the market is further segmented into diagnostics, pharmaceuticals, chemicals, cosmetics, and food. Diagnostics is further categorized into sample and type. The largest market share was captured by the pharmaceutical industry, whereas cosmetics industry was the fastest growing industry with a double digit CAGR. The prime factor contributing to the growth of pharmaceutical industry has been the attention towards the detection of toxicity during earlier stages of development.

On the basis of technology, the global market of in vitro toxicology testing is divided into cell culture, high throughput screening, cellular imaging, and omics technologies. Cell culture technology will witness the maximum growth rate in the coming years.

The methods considered for the study are cellular assays, biochemical assays, ex vivo and in silico. Cellular assays market is estimated to grow at a double digit CAGR during the forecast period (2013–2018). Cellular assays can predict the biological properties of potential drug compounds. These assays can also detect and measure cell viability, functionality and growth.

Under the applications, the market is segmented into systemic toxicity, dermal toxicity, ocular toxicity, endocrine disruption (reproductive & developmental toxicity) and others. Systemic toxicity testing was the largest segment in 2013. The increasing focus on detection of toxicity in earlier stages of development is leading to persistent requirement for human cell-based in vitro models for cardiotoxicity and liver toxicity testing which are the major reasons for drug attrition.

Europe commanded the largest share of the global market in 2013. This is attributed to the support provided by the European government for anti-animal testing laws. The government has further put ban on the production and sale of all animal tested cosmetics across the continent.

The market will be driven by increasing acceptance of in-vitro toxicology testing methods as alternatives to in vivo toxicology testing. The new technologies in the in vitro testing market help in investigating the adverse effects of environmental agents in a more mechanistic and time saving manner. Organizations such as REACH foresee that more results of in vitro and in silico methods will be included in risk assessment which will promote the use of in vitro methods for toxicology testing.

The market is dominated by Agilent Technologies (U.S.), Alere, Inc. (U.S.), Bio-Rad (U.S.), Catalent Pharma Solutions (U.S.), Charles River Laboratories (U.S.), Covance (U.S.), Cyprotex (U.K.), Eurofins Scientific, Inc (U.S.), GE Healthcare (U.K.), Life Technologies Corporation (Thermo Fisher Scientific) (U.S.), and Quest Diagnostics (U.S.).

- Agilent Technologies, Inc.
- Alere, Inc.
- Bio-Rad Laboratories, Inc.
- Bioreliance, Inc.
- Catalent
- Charles River Laboratories International, Inc.
- Covance, Inc.
- Cyprotex
- Eurofins Scientific
- GE Healthcare
- Life Technologies Corporation
- Quest Diagnostics

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