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Anti-Adhesion Products - Global Strategic Business Report Product Image

Anti-Adhesion Products - Global Strategic Business Report

  • Published: October 2012
  • Region: Global
  • 214 Pages
  • Global Industry Analysts, Inc

This report analyzes the worldwide markets for Anti-Adhesion Products in US$ Million by the following three major End-Use Segments: General/Abdominal Surgery, Pelvic/Gynecological Surgery, and Other Surgical Procedures. The report provides separate comprehensive analytics for US, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2010 through 2018. The report profiles 25 companies including many key and niche players such as Angiotech Pharmaceuticals, Inc., Anika Therapeutics, Inc., Anika Therapeutics S.R.L., Baxter International, Inc., Ethicon, Inc., Genzyme Corporation, Covidien, FzioMed, Inc., Integra LifeSciences Corporation, LifeCell Corporation, MAST Biosurgery AG, and Pathfinder Cell Therapy, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain.

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ANTI-ADHESION PRODUCTS

A GLOBAL STRATEGIC BUSINESS REPORT

CONTENTS

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-2
Quantitative Techniques & Analytics I-3
Product Definitions and Scope of Study I-3
Adhesion I-3
Anti-Adhesion Products I-3
End-Use Market Segmentation I-3
General/Abdominal Surgery I-3
Pelvic/Gynecological Surgery I-4
Other Surgical Procedures I-4

II. Executive Summary

1. MARKET OVERVIEW II-1
Post-Surgical Adhesion Prevention: A Growing Market II-1
Market Dynamics II-1
US - The Leader All the Way II-1
Market Determinants II-2
Clinicians and Healthcare Systems: Major Growth Determiners II-2
Global Market for Anti-Adhesion Products - Fast Facts II-3
Incidence of Adhesions - A Quick Note II-4
Table 1: Worldwide Incidence of Post Surgical Adhesions by
Surgical Procedure: 2011 II-4

Table 2: Worldwide Incidence of Post Surgical Adhesions
Associated Complications: 2011 II-4
New Product Development Continues to Keep Momentum II-5
New Products to Intensify Sales and Competition II-5
Table 3: Key Materials Used in Anti-Adhesion Products
(2011): Percentage Breakdown of Use by Material Type
(includes corresponding Graph/Chart) II-5
SpineShield to Ease Chances of Post-surgical Fibrosis II-6
Research and Developments II-6
NUS Unearth Role of PLA2 Inhibitor Peptide in Preventing
Post-Surgical Adhesions II-6
Growth Restraints II-6
Lack of Awareness II-6
Less Competitive Market II-6
Escalating Healthcare Cost II-7
Competition II-7
Table 4: Leading Players in the Global Anti-Adhesion Products
Market (2011): Percentage Breakdown of Revenues for Ethicon,
Genzyme, Covidien and Others (includes corresponding
Graph/Chart) II-7

2. ADVANCED WOUND CARE TECHNOLOGIES - AN OVERVIEW OF THE LARGER
MARKET II-8
Advanced Wound Closure Market II-8
Wound Closure Market over the Years II-8
Surgical Securement Market Undergoes Paradigm Shift II-9
Table 5: Global Securement Products Market (2011):
Percentage Breakdown of Market Share by Category (includes
corresponding Graph/Chart) II-9

3. PRODUCT OVERVIEW II-10
Adhesion II-10
Mechanism of Adhesion Formation II-10
Causes of Adhesions II-10
Related Complications II-10
Symptoms of Adhesion II-10
Preventive Techniques II-11
Anti-Adhesion Products II-11
Properties of an Ideal Anti-Adhesion Product II-11
Types of Adhesion Barriers II-12
Barrier Agents II-12
Oxidized Regenerated Cellulose II-12
Expanded Polytetrafluoroethylene (ePTFE) II-12
Some of the Most Widely Used Liquid Anti-Adhesion Products II-12
Crystalloids II-12
Dextran II-13
Icodextrin Solution II-13
Hyaluronic Acid II-13
Market Segmentation II-13
General/Abdominal Surgery II-13
Pelvic/Gynecological Surgery II-14
Other Surgical Procedures II-14
Review of Select Anti-Adhesion Products Available II-14
Seprafilm™ II-14
Sepracoat® II-14
HEINEGEL II-14
Heinefilm II-14
REPEL-CV II-15
INCERT®-S II-15
Interceed™ II-15
PRECLUDE™ II-15

4. PRODUCT INTRODUCTIONS/APPROVALS II-16
FzioMed Obtains CE Mark Approval for DYNAVISC® Adhesion
Barrier Gel II-16
Innocoll Receives European Approval for CollaGUARD® II-16
SyntheMed Obtains CE Mark Approval for REPEL-GYN II-16
Magen Introduces SpineShield Anti-Adhesion Product II-17
SyntheMed Obtains Brazilian Regulatory Approval for REPEL-CVTM II-17
SyntheMed Receives FDA Approval for REPEL-CV Adhesion Barrier
for Use in Pediatric Surgery II-17
SyntheMed Receives FDA Approval for Sinus Shield II-18

5. RECENT INDUSTRY ACTIVITY II-19
Innocoll Inks Licensing and Distribution Agreement with Flynn
Pharma and Inresa Arzneimittel II-19
Pergamum Concludes Patient Recruitment for Phase II Study of
PXL01 II-19
Sanofi-Aventis Takes Over Genzyme II-19
SyntheMed Merges with Pathfinder II-20
Dalton Pharma Services Signs Agreement with AdeTherapeutics II-20
Pioneer Pharma and Innocoll Sign License and Distribution
Agreement II-20
Teijin Pharma Intends to Commence Clinical Trial on Anti-
adhesion Gel II-20
Angiotech Pharma Takes over Haemacure II-21
Green Cross Forges Licensing Agreement with FAB/Anika
Therapeutics to Launch Hyalobarrier™ II-21
FzioMed Launches Oxiplex® Adhesion Barrier Gel for Spine
Surgery in South America and Asia II-21

6. CORPORATE ACTIVITY IN RECENT PAST - A PERSPECTIVE BUILDER II-22
Anika Therapeutics Takes Over Fidia Advanced Biopolymers II-22
Angiotech Pharmaceuticals and Baxter International Sign Agreement II-22
Covidien Introduces Sprayshield™ in Europe II-22

7. FOCUS ON SELECT GLOBAL PLAYERS II-23
Angiotech Pharmaceuticals, Inc. (Canada) II-23
Anika Therapeutics, Inc (US) II-23
Anika Therapeutics S.R.L. (Italy) II-23
Baxter International, Inc. (US) II-23
Ethicon, Inc. (US) II-24
Genzyme Corporation (US) II-24
Covidien (Ireland) II-24
FzioMed, Inc. (US) II-25
Integra LifeSciences Corporation (US) II-25
LifeCell Corporation (US) II-25
MAST Biosurgery AG (Switzerland) II-26
Pathfinder Cell Therapy, Inc. (US) II-26

8. GLOBAL MARKET PERSPECTIVE II-27
Table 6: World Recent Past, Current & Future Analysis for
Anti-Adhesion Products by Geographic Region - US, Europe, and
Rest of World Markets Independently Analyzed with Annual
Revenue Figures in US$ Million for Years 2010 through 2018
(includes corresponding Graph/Chart) II-27

Table 7: World Historic Review for Anti-Adhesion Products by
Geographic Region - US, Europe, and Rest of World Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) II-28

Table 8: World 15-Year Perspective for Anti-Adhesion Products
by Geographic Region - Percentage Breakdown of Annual Revenues
for US, Europe, and Rest of World Markets for Years 2004, 2011 &
2018 (includes corresponding Graph/Chart) II-29

Table 9: World Recent Past, Current & Future Analysis for
Anti-Adhesion Products in General/Abdominal Surgery by
Geographic Region - US, Europe, and Rest of World Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) II-30

Table 10: World Historic Review for Anti-Adhesion Products in
General/Abdominal Surgery by Geographic Region - US, Europe,
and Rest of World Markets Independently Analyzed with Annual
Revenue Figures in US$ Million for Years 2004 through 2009
(includes corresponding Graph/Chart) II-31

Table 11: World 15-Year Perspective for Anti-Adhesion Products
in General/Abdominal Surgery by Geographic Region - Percentage
Breakdown of Annual Revenues for US, Europe, and Rest of World
Markets for Years 2004, 2011 & 2018 (includes corresponding
Graph/Chart) II-32

Table 12: World Recent Past, Current & Future Analysis for
Anti-Adhesion Products in Pelvic/Gynecological Surgery by
Geographic Region - US, Europe, and Rest of World Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) II-33

Table 13: World Historic Review for Anti-Adhesion Products in
Pelvic/Gynecological Surgery by Geographic Region - US,
Europe, and Rest of World Markets Independently Analyzed with
Annual Revenue Figures in US$ Million for Years 2004 through
2009 (includes corresponding Graph/Chart) II-34

Table 14: World 15-Year Perspective for Anti-Adhesion Products
in Pelvic/Gynecological Surgery by Geographic Region -
Percentage Breakdown of Annual Revenues for US, Europe, and
Rest of World Markets for Years 2004, 2011 & 2018 (includes
corresponding Graph/Chart) II-35

Table 15: World Recent Past, Current & Future Analysis for
Anti-Adhesion Products in Other Surgical Procedures by
Geographic Region - US, Europe, and Rest of World Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) II-36

Table 16: World Historic Review for Anti-Adhesion Products in
Other Surgical Procedures Surgery by Geographic Region - US,
Europe, and Rest of World Markets Independently Analyzed with
Annual Revenue Figures in US$ Million for Years 2004 through
2009 (includes corresponding Graph/Chart) II-37

Table 17: World 15-Year Perspective for Anti-Adhesion Products
in Other Surgical Procedures by Geographic Region - Percentage
Breakdown of Annual Revenues for US, Europe, and Rest of World
Markets for Years 2004, 2011 & 2018 (includes corresponding
Graph/Chart) II-38

III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
Overview III-1
Growth Drivers III-1
Aging Population: A Major Growth Driver III-1
List of Select Anti-adhesion Products Marketed in the US
by Company, Composition and Indication III-2
List of Select Anti-adhesion Products Marketed in
Countries Other than the US by Company, Composition and
Indication III-2
Product Innovations/Approvals III-2
Strategic Corporate Developments III-3
Key Players III-6
B.Market Analytics III-9
Table 18: US Recent Past, Current & Future Analysis for
Anti-Adhesion Products by Application Area -
General/Abdominal Surgery, Pelvic/Gynecological Surgery, and
Other Application Markets Independently Analyzed with Annual
Revenue Figures in US$ Million for Years 2010 through 2018
(includes corresponding Graph/Chart) III-9

Table 19: US Historic Review for Anti-Adhesion Products by
Application Area -General/Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) III-10

Table 20: US 15-Year Perspective for Anti-Adhesion Products
by Application Area - Percentage Breakdown of Annual
Revenues for General/Abdominal Surgery, Pelvic/Gynecological
Surgery, and Other Application Markets for 2004, 2011 & 2018
(includes corresponding Graph/Chart) III-11

2. EUROPE III-12
A.Market Analysis III-12
Current and Future Analysis III-12
Rising Awareness to Buoy Market Growth amid Crisis-Driven
Spending Cuts III-12
European Advanced Wound Care Technologies Market - An Overview III-12
Product Approvals/Launches III-13
Key Players III-14
B.Market Analytics III-15
Table 21: European Recent Past, Current & Future Analysis
for Anti-Adhesion Products by Geographic Region - France,
Germany, Italy, UK, Spain and Rest of Europe Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-15

Table 22: European Historic Review for Anti-Adhesion
Products by Geographic Region - France, Germany, Italy, UK,
Spain and Rest of Europe Markets Independently Analyzed with
Annual Revenue Figures in US$ Million for Years 2004 through
2009 (includes corresponding Graph/Chart) III-16

Table 23: European 15-Year Perspective for Anti-Adhesion
Products by Geographic Region - Percentage Breakdown of
Annual Revenues for France, Germany, Italy, UK, Spain and
Rest of Europe Markets for Years 2004, 2011 & 2018 (includes
corresponding Graph/Chart) III-17

Table 24: European Recent Past, Current & Future Analysis
for Anti-Adhesion Products by Application Area -
General/Abdominal Surgery, Pelvic/Gynecological Surgery, and
Other Application Markets Independently Analyzed with Annual
Revenue Figures in US$ Million for Years 2010 through 2018
(includes corresponding Graph/Chart) III-18

Table 25: European Historic Review for Anti-Adhesion
Products by Application Area - General/Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) III-19

Table 26: European 15-Year Perspective for Anti-Adhesion
Products by Application Area - Percentage Breakdown of
Annual Revenues for General/Abdominal Surgery, Pelvic/
Gynecological Surgery, and Other Application Markets for
2004, 2011 & 2018 (includes corresponding Graph/Chart) III-20

2a. FRANCE III-21
Market Analysis III-21
Table 27: French Recent Past, Current & Future Analysis for
Anti-Adhesion Products by Application Area -
General/Abdominal Surgery, Pelvic/ Gynecological Surgery,
and Other Application Markets Independently Analyzed with
Annual Revenue Figures in US$ Million for Years 2010 through
2018 (includes corresponding Graph/Chart) III-21

Table 28: French Historic Review for Anti-Adhesion Products
by Application Area - General/Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) III-22

Table 29: French 15-Year Perspective for Anti-Adhesion
Products by Application Area - Percentage Breakdown of
Annual Revenues for General/Abdominal Surgery, Pelvic/
Gynecological Surgery, and Other Application Markets for
2004, 2011 & 2018 (includes corresponding Graph/Chart) III-23

2b. GERMANY III-24
Market Analysis III-24
Table 30: German Recent Past, Current & Future Analysis for
Anti-Adhesion Products by Application Area -
General/Abdominal Surgery, Pelvic/Gynecological Surgery, and
Other Application Markets Independently Analyzed with Annual
Revenue Figures in US$ Million for Years 2010 through 2018
(includes corresponding Graph/Chart) III-24

Table 31: German Historic Review for Anti-Adhesion Products
by Application Area - General/Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) III-25

Table 32: German 15-Year Perspective for Anti-Adhesion
Products by Application Area - Percentage Breakdown of
Annual Revenues for General/Abdominal Surgery, Pelvic/
Gynecological Surgery, and Other Application Markets for
2004, 2011 & 2018 (includes corresponding Graph/Chart) III-26

2c. ITALY III-27
A.Market Analysis III-27
Current and Future Analysis III-27
Key Player III-27
B.Market Analytics III-28
Table 33: Italian Recent Past, Current & Future Analysis for
Anti-Adhesion Products by Application Area -
General/Abdominal Surgery, Pelvic/Gynecological Surgery, and
Other Application Markets Independently Analyzed with Annual
Revenue Figures in US$ Million for Years 2010 through 2018
(includes corresponding Graph/Chart) III-28

Table 34: Italian Historic Review for Anti-Adhesion Products
by Application Area - General/Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) III-29

Table 35: Italian 15-Year Perspective for Anti-Adhesion
Products by Application Area - Percentage Breakdown of
Annual Revenues for General/Abdominal Surgery, Pelvic/
Gynecological Surgery, and Other Application Markets for
2004, 2011 & 2018 (includes corresponding Graph/Chart) III-30

2d. THE UNITED KINGDOM III-31
A.Market Analysis III-31
Current and Future Analysis III-31
Strategic Corporate Development III-31
B.Market Analytics III-32
Table 36: UK Recent Past, Current & Future Analysis for
Anti-Adhesion Products by Application Area -
General/Abdominal Surgery, Pelvic/ Gynecological Surgery,
and Other Application Markets Independently Analyzed with
Annual Revenue Figures in US$ Million for Years 2010 through
2018 (includes corresponding Graph/Chart) III-32

Table 37: UK Historic Review for Anti-Adhesion Products by
Application Area - General/Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) III-33

Table 38: UK 15-Year Perspective for Anti-Adhesion Products
by Application Area - Percentage Breakdown of Annual
Revenues for General/Abdominal Surgery, Pelvic/Gynecological
Surgery, and Other Application Markets for 2004, 2011 & 2018
(includes corresponding Graph/Chart) III-34

2e. SPAIN III-35
Market Analysis III-35
Table 39: Spanish Recent Past, Current & Future Analysis for
Anti-Adhesion Products by Application Area -
General/Abdominal Surgery, Pelvic/ Gynecological Surgery,
and Other Application Markets Independently Analyzed with
Annual Revenue Figures in US$ Million for Years 2010 through
2018 (includes corresponding Graph/Chart) III-35

Table 40: Spanish Historic Review for Anti-Adhesion Products
by Application Area - General/Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) III-36

Table 41: Spanish 15-Year Perspective for Anti-Adhesion
Products by Application Area - Percentage Breakdown of
Annual Revenues for General/ Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
for 2004, 2011 & 2018 (includes corresponding Graph/Chart) III-37

2f. REST OF EUROPE III-38
A.Market Analysis III-38
Current and Future Analysis III-38
Strategic Corporate Development III-38
B.Market Analytics III-39
Table 42: Rest of Europe Recent Past, Current & Future
Analysis for Anti-Adhesion Products by Application Area -
General/Abdominal Surgery, Pelvic/Gynecological Surgery, and
Other Application Markets Independently Analyzed with Annual
Revenue Figures in US$ Million for Years 2010 through 2018
(includes corresponding Graph/Chart) III-39

Table 43: Rest of Europe Historic Review for Anti-Adhesion
Products by Application Area - General/Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) III-40

Table 44: Rest of Europe 15-Year Perspective for
Anti-Adhesion Products by Application Area - Percentage
Breakdown of Annual Revenues for General/Abdominal Surgery,
Pelvic/ Gynecological Surgery, and Other Application Markets
for 2004, 2011 & 2018 (includes corresponding Graph/Chart) III-41

3. REST OF WORLD III-42
A.Market Analysis III-42
Current & Future Analysis III-42
Product Approval III-42
Strategic Corporate Developments III-42
Key Player III-43
B.Market Analytics III-44
Table 45: Rest of World Recent Past, Current & Future
Analysis for Anti-Adhesion Products by Application Area -
General/Abdominal Surgery, Pelvic/ Gynecological Surgery,
and Other Application Markets Independently Analyzed with
Annual Revenue Figures in US$ Million for Years 2010 through
2018 (includes corresponding Graph/Chart) III-44

Table 46: Rest of World Historic Review for Anti-Adhesion
Products by Application Area - General/ Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
Independently Analyzed with Annual Revenue Figures in US$
Million for Years 2004 through 2009 (includes corresponding
Graph/Chart) III-45

Table 47: Rest of World 15-Year Perspective for
Anti-Adhesion Products by Application Area - Percentage
Breakdown of Annual Revenues for General/Abdominal Surgery,
Pelvic/Gynecological Surgery, and Other Application Markets
for 2004, 2011 & 2018 (includes corresponding Graph/Chart) III-46

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 25 (including Divisions/Subsidiaries - 34)

The United States (13)
Canada (2)
Japan (2)
Europe (16)
- Germany (4)
- The United Kingdom (3)
- Italy (2)
- Rest of Europe (4)
Asia-Pacific (Excluding Japan) (3)
Middle-East (1)

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