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Frontiers in Anti-infective Drug Discovery Volume 1 - Product Image

Frontiers in Anti-infective Drug Discovery Volume 1

  • Published: January 2010
  • Region: Global
  • Bentham Science Publishers Ltd

“Frontiers in Anti-Infective Drug Discovery” is an Ebook series devoted to publishing the latest and the most important advances in Anti-Infective drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Infective drug design and discovery. Each volume is devoted to the major advances in Anti-Infective drug design and discovery. The Ebook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Volume 1
Contents
Preface i
Contributors ii
Strategies for Effective Naked-DNA Vaccination Against Infectious Diseases
Pieranna Chiarella, Emanuela Massi, Mariangela De Robertis, Vito M. Fazio
and Emanuela Signori
1

Light Activated Compounds as Patented Antimicrobial Agents
David A. Phoenix and Frederick Harris
17
Proteases and Kinases: Attractive Targets for Combating Infectious Diseases
Mona Arabshahi, Usha Bughani, Surya N. Vangapandu, Ritu Aneja,
Ramesh Chandra, Daniel Kalman and Harish Joshi
49
Antibacterial Therapy in the Elderly
Ayman M. Noreddin and Walid F. El-Khatib
70
SARS Coronavirus Anti-Infectives
Tommy R. Tong
83
Probiotics as Drugs Against Human Gastrointestinal Pathogens
Yolanda Sanz, Inmaculada Nadal and Ester Sánchez
107
Insights into the Treatment of Helicobacter pylori Infection
Campo Salvatore Maria Antonio, Hassan Cesare, Burza Maria Antonietta,
Ridola Lorenzo, Cristofari Francesca, Morini Sergio and Zullo Angelo
124
Inhibitors of Bacterial Efflux Pumps as Adjuvants in Antibacterial Therapy
and Diagnostic Tools for Detection of Resistance by Efflux
Françoise Van Bambeke, Jean-Marie Pagès and Ving J. Lee
138
Drugs Candidates in Advanced Clinical Trials Against Tuberculosis
Marcus Vinícius Nora de Souza, Marcelle de Lima Ferreira and
Raoni Schroeder B. Gonçalves
176
Drug Effects on Drug Targets: Inhibition of Enzymes by Neuroleptics,
Antimycotics, Antibiotics and Other Drugs on Human Pathogenic Amoebas
and their Anti-Proliferative Effects
Raúl N. Ondarza
202
Macrophage Inflammatory Protein 1 and CCR5 as Potential Therapeutic
Targets for HIV Infection and Acquired Immunodeficiency Syndrome
Tsuyoshi Kasama, Ryo Takahashi, Michihito Sato and Kuninobu Wakabayashi
227
Small-Molecule Inhibitors of Raf for Treatment of Malignant Diseases
Li Li, Shuhong Wu, Wei Guo and Bingliang Fang
238
Tigecycline: A New Treatment Choice Against Acinetobacter baumannii
Virginia Bosó-Ribelles, Eva Romá-Sánchez, Jorge Carmena, Cristina Cáceres
and Daniel Bautista
251
Cefepime and its Role in Pediatric Infections
Sukhbir K. Shahid
261
Antibacterial Properties of Organosulfur Anti-Infectives: A Review of
Patent Literature 1999-2009
Monika I. Konaklieva and Balbina J. Plotkin
269
A Review of the Carbapenems in Clinical Use and Clinical Trials
Tze Shien Lo, Justin M. Welch, Augusto M. Alonto and
Eileen Anne R. Vicaldo-Alonto
279
Anti-Infective Quinone Derivatives of Recent Patents
Junko Koyama
294
Targets and Patented Drugs for Chemotherapy of Chagas Disease
Vilma G. Duschak and Alicia S. Couto
323
Recent Patents on Development of Nucleic Acid-Based Antiviral Drugs
against Seasonal and Pandemic Influenza Virus Infections
Edward G. Saravolac and Jonathan P. Wong
409
Author Index 426

Editors: Dr. Atta-ur-Rahman; Dr. M. Iqbal Choudhary

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